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cost of illness (2) 2
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1. Understanding patient perspectives on communication about the cost of cancer care: A review of the literature
by Hofstatter, Erin W
Journal of Oncology Practice, ISSN 1554-7477, 07/2010, Volume 6, Issue 4, pp. 188 - 192
Patient-physician communication about cost when making treatment decisions has been promoted as a potential solution to the rising cost of oncologic care and... 
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2. Full Text Advances in the diagnosis of hereditary kidney cancer: Initial results of a multigene panel test
by Nguyen, Kevin A and Syed, Jamil S and Espenschied, Carin R and LaDuca, Holly and Bhagat, Ansh M and Suarez‐Sarmiento, Alfredo and O'Rourke, Timothy K and Brierley, Karina L and Hofstatter, Erin W and Shuch, Brian
Cancer, ISSN 0008-543X, 11/2017, Volume 123, Issue 22, pp. 4363 - 4371
BACKGROUND Panel testing has been recently introduced to evaluate hereditary cancer; however, limited information is available regarding its use in kidney... 
early diagnosis | hereditary | kidney neoplasms | neoplastic syndromes | genetic testing | age of onset | PREDISPOSES | AMERICAN-COLLEGE | RISK | MEDICAL GENETICS | LYNCH SYNDROME | BREAST | MELANOMA | ONCOLOGY | COLORECTAL-CANCER | MUTATION | CARCINOMA | Early Detection of Cancer - trends | Genetic Predisposition to Disease | Kidney Neoplasms - genetics | Early Detection of Cancer - methods | Humans | Middle Aged | Transcriptome | Neoplastic Syndromes, Hereditary - diagnosis | Male | Proto-Oncogene Proteins - genetics | DNA Mutational Analysis - methods | Kidney Neoplasms - diagnosis | Tumor Suppressor Proteins - genetics | Adult | Female | Neoplastic Syndromes, Hereditary - genetics | Retrospective Studies | Genetic Testing - trends | Usage | Cancer patients | Diagnosis | Panel analysis | Health aspects | Kidney cancer | Tuberous sclerosis 2 protein | Microphthalmia-associated transcription factor | Mesenchyme | Genes | Disorders | Tuberous sclerosis | Homology | Histology | Regression analysis | Multivariate analysis | Patients | Genetic screening | c-Met protein | Fumarate hydratase | TSC2 protein | Genetic counseling | Genetics | Mutation | Age | Cancer | Kidney transplantation
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3. Understanding patients' attitudes toward communication about the cost of cancer care
by Bullock, Andrea J and Hofstatter, Erin W and Yushak, Melinda L and Buss, Mary K
Journal of Oncology Practice, ISSN 1554-7477, 07/2012, Volume 8, Issue 4, pp. e50 - e58
Recent publications have promoted physician-patient communication on cost as a means of decreasing overall spending and minimizing patients' financial burden... 
Decision Making | Drug Costs | Neoplasms - economics | Medicare | United States | Humans | Middle Aged | Cost of Illness | Male | Physician-Patient Relations | Health Knowledge, Attitudes, Practice | Neoplasms - drug therapy | Young Adult | Health Care Costs | Medical Oncology - economics | Aged, 80 and over | Adult | Female | Surveys and Questionnaires | Aged | Medicaid | Insurance, Health
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4. Full Text Use of Endocrine Therapy for Breast Cancer Risk Reduction: ASCO Clinical Practice Guideline Update
by Visvanathan, Kala and Fabian, Carol J and Bantug, Elissa and Brewster, Abenaa M and Davidson, Nancy E and DeCensi, Andrea and Floyd, Justin D and Garber, Judy E and Hofstatter, Erin W and Khan, Seema A and Katapodi, Maria C and Pruthi, Sandhya and Raab, Rachal and Runowicz, Carolyn D and Somerfield, Mark R
Journal of Clinical Oncology, ISSN 0732-183X, 11/2019, Volume 37, Issue 33, pp. 3152 - 3165
PURPOSE To update the ASCO guideline on pharmacologic interventions for breast cancer risk reduction and provide guidance on clinical issues that arise when... 
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5. Full Text Relationship between complete pathologic response to neoadjuvant chemotherapy and survival in triple-negative breast cancer
by Hatzis, Christos and Symmans, W. Fraser and Zhang, Ya and Gould, Rebekah E and Moulder, Stacy L and Hunt, Kelly K and Abu-Khalaf, Maysa and Hofstatter, Erin W and Lannin, Donald and Chagpar, Anees B and Pusztai, Lajos
Clinical Cancer Research, ISSN 1078-0432, 01/2016, Volume 22, Issue 1, pp. 26 - 33
Purpose: Pathologic complete response (pCR) to neoadjuvant chemotherapy reflects the cytotoxic efficacy of a drug, but patient survival is influenced by many... 
TRIAL | WEEKLY PACLITAXEL | PREOPERATIVE CHEMOTHERAPY | EPIRUBICIN | THERAPY | COMPLETE REMISSION | ONCOLOGY | DOXORUBICIN | OPEN-LABEL | BURDEN | ADJUVANT TRASTUZUMAB | Prognosis | Follow-Up Studies | Humans | Middle Aged | Kaplan-Meier Estimate | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Treatment Outcome | Combined Modality Therapy | Triple Negative Breast Neoplasms - mortality | Triple Negative Breast Neoplasms - drug therapy | Biomarkers, Tumor | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Survival Analysis | Triple Negative Breast Neoplasms - pathology | Adult | Female | Neoadjuvant Therapy | Aged | Neoplasm Staging | Odds Ratio
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6. Full Text Advances in the diagnosis of hereditary kidney cancer: Initial results of a multigene panel test
: Multigene Panel Test for Kidney Cancer
by Nguyen, Kevin A and Syed, Jamil S and Espenschied, Carin R and LaDuca, Holly and Bhagat, Ansh M and Suarez-Sarmiento, Alfredo and O'Rourke, Timothy K and Brierley, Karina L and Hofstatter, Erin W and Shuch, Brian
Cancer, ISSN 0008-543X, 11/2017, Volume 123, Issue 22, pp. 4363 - 4371
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7. Full Text State of the Art in Imaging and Chemoprevention for High-Risk Patients
by Hofstatter, Erin W and Andrejeva, Liva and Chagpar, Anees B
Current Breast Cancer Reports, ISSN 1943-4588, 6/2013, Volume 5, Issue 2, pp. 125 - 133
Recent developments in breast imaging technology and chemoprevention clinical trials have provided promising new options for patients at increased risk of... 
Breast cancer risk | Chemoprevention | Oncology | Internal Medicine | Breast mammography with tomosynthesis | Tamoxifen | Exemestane | Breast ultrasonography | Breast cancer prevention | Medicine & Public Health | Raloxifene | Breast MRI | Surgical Oncology | Breast cancer screening | Antimitotic agents | Prevention | Medical colleges | Care and treatment | Diagnostic imaging | Antineoplastic agents | Health aspects | Medical imaging equipment | Cancer
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8. Impact of financial burden of cancer on survivors' quality of life
by Fenn, Kathleen M and Evans, Suzanne B and McCorkle, Ruth and DiGiovanna, Michael P and Pusztai, Lajos and Sanft, Tara and Hofstatter, Erin W and Killelea, Brigid K and Tish Knobf, M and Lannin, Donald R and Abu-Khalaf, Maysa and Horowitz, Nina R and Chagpar, Anees B
Journal of Oncology Practice, ISSN 1554-7477, 09/2014, Volume 10, Issue 5, pp. 332 - 338
Little is known about the relationship between the financial burden of cancer and the physical and emotional health of cancer survivors. We examined the... 
Multivariate Analysis | Neoplasms - economics | United States | Humans | Middle Aged | Survivors | Cost of Illness | Male | Antineoplastic Agents - therapeutic use | Neoplasms - psychology | Antineoplastic Agents - economics | Regression Analysis | Health Surveys | Quality of Life | Female | Aged
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9. Full Text Uptake of exemestane chemoprevention in postmenopausal women at increased risk for breast cancer
by Aktasa, Bilge and Sorkinb, Mia and Pusztaia, Lajos and Hofstattera, Erin W
European Journal of Cancer Prevention, ISSN 0959-8278, 2016, Volume 25, Issue 1, pp. 3 - 8
Despite their efficacy, uptake of selective estrogen receptor modulators for breast cancer chemoprevention remains low. Exemestane, an aromatase inhibitor, has... 
Exemestan | Breast cancer chemoprevention | aromatase inhibitors | Postmenopausal women | Chemoprevention uptake | TAMOXIFEN USE | PHARMACOLOGICAL INTERVENTIONS | exemestane | SURGICAL ADJUVANT BREAST | postmenopausal women | breast cancer chemoprevention | chemoprevention uptake | PRIMARY-CARE | ONCOLOGY | RANDOMIZED PHASE-II | CLINICAL-PRACTICE GUIDELINE | BOWEL PROJECT P-1 | STEROIDAL AROMATASE INHIBITOR | AMERICAN SOCIETY | PREVENTION TRIAL | Prognosis | Follow-Up Studies | Risk Assessment | Humans | Middle Aged | Breast Neoplasms - prevention & control | Carcinoma, Intraductal, Noninfiltrating - pathology | Selective Estrogen Receptor Modulators - therapeutic use | Breast Neoplasms - pathology | Postmenopause | Carcinoma, Ductal, Breast - pathology | Female | Aged | Androstadienes - therapeutic use | Carcinoma, Ductal, Breast - prevention & control | Retrospective Studies | Neoplasm Staging | Carcinoma, Intraductal, Noninfiltrating - prevention & control | Review | Breast Cancer
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10. Full Text Single-arm, neoadjuvant, phase II trial of pertuzumab and trastuzumab administered concomitantly with weekly paclitaxel followed by 5-fluoruracil, epirubicin, and cyclophosphamide (FEC) for stage I–III HER2-positive breast cancer
by Foldi, Julia and Mougalian, Sarah and Silber, Andrea and Lannin, Donald and Killelea, Brigid and Chagpar, Anees and Horowitz, Nina and Frederick, Courtney and Rispoli, Lawrence and Burrello, Trisha and Abu-Khalaf, Maysa and Sabbath, Kert and Sanft, Tara and Brandt, Debra S and Hofstatter, Erin W and Hatzis, Christos and DiGiovanna, Michael P and Pusztai, Lajos
Breast Cancer Research and Treatment, ISSN 0167-6806, 6/2018, Volume 169, Issue 2, pp. 333 - 340
The purpose of this two-cohort Phase II trial was to estimate the pathologic complete response (pCR: ypT0/is ypN0) rate when trastuzumab plus pertuzumab are... 
Neoadjuvant therapy | HER-2-positive | Medicine & Public Health | Pertuzumab | Pathological complete response | Oncology | Breast cancer | Trastuzumab | MULTICENTER | OPEN-LABEL | COMBINATION | PLUS TRASTUZUMAB | CHEMOTHERAPY | ADJUVANT TRASTUZUMAB | LAPATINIB | THERAPY | ONCOLOGY | CLINICAL-TRIALS | CONCURRENT | Cyclophosphamide - administration & dosage | Receptor, ErbB-2 - genetics | Humans | Middle Aged | Epirubicin - administration & dosage | Cyclophosphamide - adverse effects | Drug-Related Side Effects and Adverse Reactions - pathology | Antibodies, Monoclonal, Humanized - administration & dosage | Fluorouracil - administration & dosage | Fluorouracil - adverse effects | Adult | Female | Paclitaxel - administration & dosage | Taxoids - adverse effects | Breast Neoplasms - epidemiology | Antibodies, Monoclonal, Humanized - adverse effects | Paclitaxel - adverse effects | Trastuzumab - adverse effects | Trastuzumab - administration & dosage | Breast Neoplasms - drug therapy | Taxoids - administration & dosage | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Neoadjuvant Therapy - adverse effects | Bridged-Ring Compounds - adverse effects | Bridged-Ring Compounds - administration & dosage | Drug-Related Side Effects and Adverse Reactions - classification | Epirubicin - adverse effects | Anthracyclines | Cyclophosphamide | Analysis | Adjuvant treatment | Clinical trials | Product development | Health aspects | Cancer
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11. Full Text Patient preferences regarding incidental genomic findings discovered during tumor profiling
by Yushak, Melinda L and Han, Gang and Bouberhan, Sara and Epstein, Lianne and DiGiovanna, Michael P and Mougalian, Sarah S and Sanft, Tara B and Abu‐Khalaf, Maysa M and Chung, Gina G and Stein, Stacey M and Goldberg, Sarah B and Pusztai, Lajos and Hofstatter, Erin W
Cancer, ISSN 0008-543X, 05/2016, Volume 122, Issue 10, pp. 1588 - 1597
BACKGROUND During the process of tumor profiling, there is the potential to detect germline variants. To the authors' knowledge, there currently is no accepted... 
genome | genomics | disclosure | questionnaire | incidental findings | germline mutation | ACMG RECOMMENDATIONS | RETURN | ONCOLOGY | GENETICS | CLINICAL EXOME | ATTITUDES | Cross-Sectional Studies | Humans | Middle Aged | Male | Neoplasms - psychology | Disclosure | Neoplasms - genetics | Aged, 80 and over | Germ-Line Mutation | Adult | Surveys and Questionnaires | Aged | Neoplasms - pathology | Cohort Studies | Patient Preference - psychology | Prevention | Research | Diagnosis | Gene mutations | Genomics | Cancer
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12. Full Text Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice
by Burga, Laura N and Hu, Hai and Juvekar, Ashish and Tung, Nadine M and Troyan, Susan L and Hofstatter, Erin W and Wulf, Gerburg M
Breast Cancer Research, ISSN 1465-5411, 03/2011, Volume 13, Issue 2, pp. R30 - R30
Introduction: Women who carry a BRCA1 mutation typically develop "triple-negative" breast cancers (TNBC), defined by the absence of estrogen receptor (ER),... 
STEM-CELLS | GENE | MODELS | ONCOLOGY | MUTATION CARRIERS | SPORADIC BREAST-CANCER | PROLIFERATION | BINDING-SITES | TUMORS | TUMORIGENESIS | ERLOTINIB | Erlotinib Hydrochloride | Receptors, Estrogen - metabolism | Epithelial Cells - metabolism | Humans | Retinal Dehydrogenase - metabolism | Mammary Neoplasms, Experimental - metabolism | Breast - metabolism | Mammary Neoplasms, Experimental - genetics | Genes, p53 | Receptor, Epidermal Growth Factor - metabolism | RNA Interference | Isoenzymes - metabolism | BRCA1 Protein - metabolism | Female | Genes, BRCA1 | Mammary Neoplasms, Experimental - prevention & control | Breast - cytology | Mice, Inbred C57BL | Cells, Cultured | Epidermal Growth Factor - metabolism | Mice, Knockout | Animals | Mammary Glands, Animal - metabolism | Cell Transformation, Neoplastic | Mammary Tumor Virus, Mouse | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Protein Kinase Inhibitors - pharmacology | Quinazolines - pharmacology | Prevention | BRCA mutations | Breast cancer | Genetic aspects | Research | Health aspects | Risk factors
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13. Full Text Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability
by Lam, Prudence B and Burga, Laura N and Wu, Bryan P and Hofstatter, Erin W and Lu, Kun Ping and Wulf, Gerburg M
Molecular Cancer, ISSN 1476-4598, 12/2008, Volume 7, Issue 1, pp. 91 - 91
Overexpression of HER-2/Neu occurs in about 25-30% of breast cancer patients and is indicative of poor prognosis. While Her2/Neu overexpression is primarily a... 
TRANSCRIPTIONAL ACTIVITY | THERAPY | TUMOR PROGRESSION | ONCOLOGY | CYCLIN D1 | PHOSPHORYLATION | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROSTATE-CANCER | SQUAMOUS-CELL CARCINOMA | MONOCLONAL-ANTIBODY | MTOR INHIBITOR | Immunohistochemistry | Transcription, Genetic - drug effects | Peptidylprolyl Isomerase - deficiency | Antibodies, Monoclonal - pharmacology | Humans | Receptor, ErbB-2 - metabolism | Peptidylprolyl Isomerase - antagonists & inhibitors | NIMA-Interacting Peptidylprolyl Isomerase | Down-Regulation - drug effects | Sirolimus - pharmacology | Antibodies, Monoclonal, Humanized | Breast Neoplasms - enzymology | Breast Neoplasms - genetics | Protein Processing, Post-Translational - drug effects | Breast Neoplasms - pathology | Protein Stability - drug effects | Cell Line, Tumor | Peptidylprolyl Isomerase - metabolism | Cell Proliferation - drug effects | Peptidylprolyl Isomerase - genetics | Proteasome Inhibitors | Trastuzumab | Prognosis | Breast cancer | Genetic aspects | Research | Gene expression | Health aspects | Oncogenes
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14. Full Text Patient preferences regarding incidental genomic findings discovered during tumor profiling
: Patient Preferences and Tumor Profiling
by Yushak, Melinda L and Han, Gang and Bouberhan, Sara and Epstein, Lianne and DiGiovanna, Michael P and Mougalian, Sarah S and Sanft, Tara B and Abu-Khalaf, Maysa M and Chung, Gina G and Stein, Stacey M and Goldberg, Sarah B and Pusztai, Lajos and Hofstatter, Erin W
Cancer, ISSN 0008-543X, 05/2016, Volume 122, Issue 10, pp. 1588 - 1597
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15. Full Text The Number of Lymph Nodes Dissected in Breast Cancer Patients Influences the Accuracy of Prognosis
by Wiznia, Lauren E and Wiznia, Lauren E and Lannin, Donald R and Lannin, Donald R and Evans, Suzanne B and Evans, Suzanne B and Hofstatter, Erin W and Hofstatter, Erin W and Horowitz, Nina R and Horowitz, Nina R and Killelea, Brigid K and Killelea, Brigid K and Tsangaris, Theodore N and Tsangaris, Theodore N and Chagpar, Anees B and Chagpar, Anees B
Annals of Surgical Oncology, ISSN 1068-9265, 2/2014, Volume 21, Issue 2, pp. 389 - 394
Recent trials have suggested that axillary node dissection may not be warranted in some breast cancer patients with one to two positive nodes. Given that lymph... 
Oncology | Medicine & Public Health | Surgical Oncology | Surgery | TRIAL | SURVIVAL | SURGERY | WOMEN | ONCOLOGY | BIOPSY | NO AXILLARY DISSECTION | FOLLOW-UP | RATIO | RADICAL-MASTECTOMY | CARCINOMA | Breast Neoplasms - surgery | Lymph Nodes - pathology | Prognosis | Follow-Up Studies | Lymph Nodes - surgery | Humans | Middle Aged | Male | Survival Rate | Lymph Node Excision - mortality | Young Adult | Breast Neoplasms - pathology | Adolescent | Aged, 80 and over | Adult | Breast Neoplasms - mortality | Female | Aged | Neoplasm Staging | Cohort Studies | Medical colleges | Cancer patients | Breast cancer | Health aspects | Analysis
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16. Full Text PALB2 mutations in familial breast and pancreatic cancer
by Hofstatter, Erin W and Domchek, Susan M and Miron, Alexander and Garber, Judy and Wang, Molin and Componeschi, Kathryn and Boghossian, Leigh and Miron, Penelope L and Nathanson, Katherine L and Tung, Nadine
Familial Cancer, ISSN 1389-9600, 6/2011, Volume 10, Issue 2, pp. 225 - 231
PALB2 (Partner And Localizer of BRCA2) binds to and co-localizes with BRCA2 in DNA repair. Germline mutations in PALB2 have been identified in approximately... 
Human Genetics | Biomedicine | Pancreatic cancer | Cancer Research | Breast cancer | BRCA2 | Epidemiology | PALB2 | Biomedicine general | ELECTROPHORESIS | ONCOLOGY | BRCA2-INTERACTING PROTEIN | GENES | GENETICS & HEREDITY | Genetic Predisposition to Disease | Breast Neoplasms - genetics | Humans | Middle Aged | Tumor Suppressor Proteins - genetics | Adult | Female | Pancreatic Neoplasms - genetics | Aged | Mutation | Nuclear Proteins - genetics | Fanconi Anemia Complementation Group N Protein
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17. Full Text Increased epigenetic age in normal breast tissue from luminal breast cancer patients
by Hofstatter, Erin W and Horvath, Steve and Dalela, Disha and Gupta, Piyush and Chagpar, Anees B and Wali, Vikram B and Bossuyt, Veerle and Storniolo, Anna Maria and Hatzis, Christos and Patwardhan, Gauri and Von Wahlde, Marie-Kristin and Butler, Meghan and Epstein, Lianne and Stavris, Karen and Sturrock, Tracy and Au, Alexander and Kwei, Stephanie and Pusztai, Lajos
Clinical Epigenetics, ISSN 1868-7075, 08/2018, Volume 10, Issue 1, pp. 112 - 11
Background: Age is one of the most important risk factors for developing breast cancer. However, age-related changes in normal breast tissue that potentially... 
Epigenomics | Humans | Biomarkers | Breast | DNA methylation | Epigenetics | Breast neoplasms | Genome | Multivariate analysis | Smoking | DNA METHYLATION AGE | ONCOLOGY | CLOCK | Epigenetic inheritance | Cancer patients | Patient outcomes | Analysis | Breast cancer | Research | Methylation | Health aspects | Mortality | Data processing | Arthritis | Genomes | Risk factors | DNA microarrays | Womens health | Surgery | Aging | Age | Deoxyribonucleic acid--DNA
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18. Full Text The benefit and burden of cancer screening in Li-fraumeni syndrome: A case report
by Jhaveri, Ami P and Bale, Allen and Lovick, Niki and Zuckerman, Kaye and Deshpande, Hari and Rath, Kristina and Schwartz, Peter and Hofstatter, Erin W
Yale Journal of Biology and Medicine, ISSN 0044-0086, 06/2015, Volume 88, Issue 2, p. 181
Li-Fraumeni syndrome is a rare cancer predisposition syndrome classically associated with remarkably early onset of cancer in families with a typical spectrum... 
Case report | Genetic counseling | TP53 | Cancer | Cancer screening | Li-Fraumeni syndrome | Li-Fraumeni Syndrome - genetics | Neoplasms, Multiple Primary - therapy | Genetic Predisposition to Disease - genetics | Li-Fraumeni Syndrome - therapy | Neoplasms, Multiple Primary - genetics | Early Detection of Cancer - methods | Humans | Female | Treatment Outcome | Li-Fraumeni Syndrome - diagnosis | Child | Neoplasms, Multiple Primary - diagnosis
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19. Full Text Influence of a 21-Gene Recurrence Score Assay on Chemotherapy Delivery in Breast Cancer
by Rutter, Charles E and Yao, Xiaopan and Mancini, Brandon R and Aminawung, Jenerius A and Chagpar, Anees B and Saglam, Ozlen and Hofstatter, Erin W and Abu-Khalaf, Maysa and Gross, Cary P and Evans, Suzanne B
Clinical Breast Cancer, ISSN 1526-8209, 2016, Volume 16, Issue 1, pp. 59 - 62
Micro-Abstract The results of the Oncotype DX assay help direct chemotherapy usage for breast cancer. However, its influence in the decision-making process is... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Recurrence | Oncotype | Chemotherapy | Score | Adjuvant | IMPACT | ONCOLOGY | RECOMMENDATIONS | GENE-EXPRESSION | RISK | Humans | Middle Aged | Gene Expression Profiling - methods | Antineoplastic Agents - therapeutic use | Breast Neoplasms - drug therapy | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Chemotherapy, Adjuvant - methods | Aged, 80 and over | Adult | Female | Neoplasm Recurrence, Local - genetics | Aged | Retrospective Studies
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