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Proteomics, ISSN 1615-9853, 05/2013, Volume 13, Issue 9, pp. 1519 - 1527
The aspartyl protease BACE 1 cleaves neuregulin 1 and is involved in myelination and is a candidate drug target for A lzheimer's disease, where it acts as the... 
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 01/2015, Volume 96, Issue 1, pp. 136 - 146
Journal Article
by Schormair, Barbara and Zhao, Chen and Bell, Steven and Bell, Robert K and Tilch, Erik and Salminen, Aaro V and Pütz, Benno and Dauvilliers, Yves and Stefani, Ambra and Högl, Birgit and Poewe, Werner and Kemlink, David and Sonka, Karel and Bachmann, Cornelius G and Paulus, Walter and Trenkwalder, Claudia and Oertel, Wolfgang H and Hornyak, Magdolna and Teder-Laving, Maris and Metspalu, Andres and Hadjigeorgiou, Georgios M and Polo, Olli and Fietze, Ingo and Ross, Owen A and Wszolek, Zbigniew and Butterworth, Adam S and Soranzo, Nicole and Ouwehand, Willem H and Roberts, David J and Danesh, John and Allen, Richard P and Earley, Christopher J and Ondo, William G and Xiong, Lan and Montplaisir, Jacques and Gan-Or, Ziv and Perola, Markus and Vodicka, Pavel and Dina, Christian and Franke, Andre and Tittmann, Lukas and Stewart, Alexandre F R and Shah, Svati H and Gieger, Christian and Peters, Annette and Rouleau, Guy A and Berger, Klaus and Oexle, Konrad and Di Angelantonio, Emanuele and Hinds, David A and Müller-Myhsok, Bertram and Winkelmann, Juliane and Balkau, B and Ducimetière, P and Eschwège, E and Rancière, F and Alhenc-Gelas, F and Gallois, Y and Girault, A and Fumeron, F and Marre, M and Roussel, R and Bonnet, F and Bonnefond, A and Cauchi, S and Froguel, P and Cogneau, J and Born, C and Caces, E and Cailleau, M and Lantieri, O and Moreau, JG and Rakotozafy, F and Tichet, J and Vol, S and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bryc, Katarzyna and Elson, Sarah L and Fontanillas, Pierre and Furlotte, Nicholas A and Hromatka, Bethann S and Huber, Karen E and Kleinman, Aaron and Litterman, Nadia K and McIntyre, Matthew H and Mountain, Joanna L and Northover, Carrie AM and Pitts, Steven J and Sathirapongsasuti, J Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tian, Chao and Tung, Joyce Y and Vacic, Vladimir and Wilson, Catherine H and Collaboration 23andMe Res Team and DESIR Study Grp and DESIR study group and 23andMe Research Team
The Lancet Neurology, ISSN 1474-4422, 11/2017, Volume 16, Issue 11, pp. 898 - 907
Journal Article
by Hogl, B
JAMA NEUROLOGY, ISSN 2168-6149, 04/2017, Volume 74, Issue 4, pp. 387 - 388
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e21337
Regulated intramembrane proteolysis of the amyloid precursor protein (APP) by the protease activities alpha-, beta-and gamma-secretase controls the generation... 
BETA-SECRETASE | ALPHA-SECRETASE | REGULATED INTRAMEMBRANE PROTEOLYSIS | ALZHEIMERS-DISEASE | FAMILY-MEMBERS | BIOLOGY | TRANSMEMBRANE DOMAIN | CELL-ADHESION | DEFICIENT MICE | HIPPOCAMPAL-NEURONS | CHONDROITIN SULFATE GLYCOSAMINOGLYCAN | Amyloid Precursor Protein Secretases - genetics | Amyloid beta-Protein Precursor - chemistry | Humans | Molecular Sequence Data | Gene Knockdown Techniques | Membrane Proteins - deficiency | Nerve Tissue Proteins - chemistry | Arginine | Amyloid beta-Protein Precursor - metabolism | HEK293 Cells | Membrane Proteins - metabolism | Neurons - metabolism | Binding Sites | Amino Acid Sequence | Membrane Proteins - genetics | ADAM Proteins - deficiency | ADAM10 Protein | Nerve Tissue Proteins - metabolism | ADAM Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Animals | Valine | Aspartic Acid Endopeptidases - metabolism | Amyloid Precursor Protein Secretases - deficiency | Cell Line, Tumor | Protein Binding | Mice | ADAM Proteins - genetics | Cell culture | Peptides | Antibodies | Amino acids | Homology | Nervous system | Biochemistry | Leucine | Proteins | Neurotoxicity | Proteolysis | Precursors | Cleavage | Alzheimer's disease | Enzymes | b-Site APP cleaving enzyme 1 | Alanine | Cytokines | Neurons | RNA-mediated interference | Mass spectroscopy | Ribonucleic acid--RNA | Amyloid precursor protein | N-Terminus | Cell lines | Biomarkers | β-Amyloid | Alzheimers disease | Mass spectrometry | Secretase | RNA | Ribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e71836
Journal Article
Lancet Neurology, The, ISSN 1474-4422, 2013, Volume 12, Issue 12, pp. 1141 - 1150
Journal Article