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Journal of Molecular Biology, ISSN 0022-2836, 2019
The genus Aspergillus is ubiquitous in the environment and contains a number of species, primarily A. fumigatus, that cause mold-associated disease in humans.... 
Aspergillus | pathogenesis | innate immunity | mycology | host defense
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 05/2019, Volume 20, Issue 5, pp. 559 - 559
The C-type lectin receptor-Syk (spleen tyrosine kinase) adaptor CARD9 facilitates protective antifungal immunity within the central nervous system (CNS), as... 
INFLAMMATORY MONOCYTES | ACTIVATION | SUSCEPTIBILITY | ASPARTYL PROTEINASES | CENTRAL-NERVOUS-SYSTEM | IMMUNOLOGY | ASTROCYTES | CELL | HOST PROTECTION | DEFICIENCY | FUNGAL-INFECTIONS | Candidiasis - genetics | Microglia - metabolism | Brain - microbiology | Inflammasomes - metabolism | Chemokine CXCL1 - genetics | Interleukin-1beta - genetics | Candidiasis - microbiology | CARD Signaling Adaptor Proteins - genetics | Host-Pathogen Interactions - immunology | Brain - metabolism | CARD Signaling Adaptor Proteins - metabolism | Microglia - immunology | Interleukin-1beta - metabolism | Candida albicans - physiology | Neutrophils - microbiology | Candidiasis - immunology | Chemokine CXCL1 - metabolism | Cytokines - genetics | Microglia - microbiology | Neutrophils - metabolism | Cytokines - immunology | Neutrophil Infiltration - immunology | CARD Signaling Adaptor Proteins - immunology | Cytokines - metabolism | Neutrophils - immunology | Interleukin-1beta - immunology | Mice, Transgenic | Candida albicans - immunology | Neutrophil Infiltration - genetics | Inflammasomes - genetics | Mice, Knockout | Chemokine CXCL1 - immunology | Animals | Inflammasomes - immunology | Brain - immunology | Spleen | Tyrosine | Pathogens | Fungicides | CXCR2 protein | Gene regulation | Neutrophils | Central nervous system | Leukocytes (neutrophilic) | Kinases | IL-1β | Immunity | Microglia | Recruitment | Fungi | Clonal deletion | Fungal diseases | Interleukin 1 | Mycotoxins | Deletion | Syk protein | c-Fos protein | Protein-tyrosine kinase | Chemokines
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 04/2015, Volume 17, Issue 4, pp. 421 - 423
Vaccines are needed to combat the global rise in fungal diseases. In this issue of , identify calnexin as a target of antigen-specific CD4 T cell responses... 
MICROBIOLOGY | STAPHYLOCOCCUS-AUREUS | MICE | VIROLOGY | PARASITOLOGY | CD4-Positive T-Lymphocytes - immunology | Epitopes - immunology | Ascomycota - immunology | Animals | Calnexin - immunology | Antigens, Fungal - immunology | Cell Proliferation - drug effects | CD4-Positive T-Lymphocytes - drug effects | Mycoses | Vaccines | Antigenic determinants
Journal Article
ILAR journal, ISSN 1084-2020, 12/2018, Volume 59, Issue 1, pp. 40 - 50
Over 60% of NIH extramural funding involves animal models, and approximately 80% to 90% of these are mouse models of human disease. It is critical to... 
Journal Article
PLoS Pathogens, ISSN 1553-7366, 07/2015, Volume 11, Issue 7
  Two functional microbial reporters have been used to distinguish active invasion from phagocytic uptake.\n The feasibility of these genetic manipulations... 
Flow cytometry | Dyes | Mortality | Physiology | Parasites | Immune system
Journal Article
Current Opinion in Infectious Diseases, ISSN 0951-7375, 08/2017, Volume 30, Issue 4, pp. 364 - 371
Journal Article
Journal of Immunological Methods, ISSN 0022-1759, 08/2014, Volume 410, pp. 100 - 112
Journal Article
Journal Article
Journal Article