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Neuro-oncology, ISSN 1522-8517, 07/2019, Volume 21, Issue 9, pp. 1089 - 1090
Journal Article
JNCCN Journal of the National Comprehensive Cancer Network, ISSN 1540-1405, 05/2018, Volume 16, Issue 5S, pp. 642 - 645
The 2016 WHO Classification of Tumors of the Central Nervous System integrated molecular biomarkers into the classifications of malignant gliomas. Several... 
PHASE-III TRIAL | ORGANIZATION | ADJUVANT PROCARBAZINE | OLIGODENDROGLIOMA | ONCOLOGY | GENOMIC ANALYSIS | CLASSIFICATION | MUTATIONS | RADIOTHERAPY | CHEMOTHERAPY | TEMOZOLOMIDE
Journal Article
Science, ISSN 0036-8075, 07/2017, Volume 357, Issue 6349, pp. 409 - 413
The genomes of cancers deficient in mismatch repair contain exceptionally high numbers of somatic mutations. In a proof-of-concept study, we previously showed... 
CELL LUNG-CANCER | SURVIVAL | COLORECTAL CARCINOMAS | RECEIVING NIVOLUMAB | IMMUNOTHERAPY | MICROSATELLITE INSTABILITY | MULTIDISCIPLINARY SCIENCES | LONG-TERM SAFETY | NEOANTIGENS | CHECKPOINT BLOCKADE | LYMPHOCYTES | Neoplastic Syndromes, Hereditary - immunology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Neoplastic Syndromes, Hereditary - mortality | Young Adult | Colorectal Neoplasms - therapy | Brain Neoplasms - immunology | DNA Mismatch Repair | Aged, 80 and over | Adult | Female | Neoplastic Syndromes, Hereditary - genetics | Brain Neoplasms - mortality | Biomarkers, Tumor - antagonists & inhibitors | Colorectal Neoplasms - mortality | Antibodies, Monoclonal, Humanized - therapeutic use | Antigens, Neoplasm - immunology | Brain Neoplasms - genetics | Disease-Free Survival | Colorectal Neoplasms - immunology | Cell Cycle Checkpoints - drug effects | Brain Neoplasms - therapy | Neoplastic Syndromes, Hereditary - therapy | T-Lymphocytes - immunology | Aged | Mutation | Programmed Cell Death 1 Receptor - immunology | Colorectal cancer | Genetic aspects | Nucleotide sequencing | Health aspects | DNA repair | Methods | Tumors | DNA sequencing | Yeast | PD-1 protein | Antibodies | Clinical trials | Genomes | Functional analysis | Lymphocytes T | Patients | Survival | Colon cancer | Immune checkpoint | Immunotherapy | Mismatch repair | Pancreatic cancer | Biomarkers | Bioindicators | Colon | Solid tumors | Genetic recombination | Repair | Cancer | Apoptosis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2015, Volume 112, Issue 31, pp. 9704 - 9709
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi166 - vi166
Abstract BACKGROUND H3F3A mutations define the entity of Diffuse Midline Glioma, which was added to the WHO 2016 classification. There have been several... 
Journal Article
Nature, ISSN 0028-0836, 08/2018, Volume 560, Issue 7718, pp. 387 - 391
B cell receptor (BCR) signalling has emerged as a therapeutic target in B cell lymphomas, but inhibiting this pathway in diffuse large B cell lymphoma (DLBCL)... 
PATHOGENESIS | SURVIVAL | B-CELL LYMPHOMA | INHIBITION | MULTIDISCIPLINARY SCIENCES | KINASE | GENE-EXPRESSION | IBRUTINIB | TARGETS | REQUIRES | SUBGROUPS | Pyrazoles - therapeutic use | TOR Serine-Threonine Kinases - metabolism | Humans | Toll-Like Receptor 9 - genetics | NF-kappa B - metabolism | Lymphoma, Large B-Cell, Diffuse - metabolism | Receptors, Antigen, B-Cell - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | Drug Design | Female | Tumor Cells, Cultured | Pyrazoles - pharmacology | Lymphoma, Large B-Cell, Diffuse - pathology | Carcinogenesis - genetics | Myeloid Differentiation Factor 88 - genetics | Receptors, Antigen, B-Cell - antagonists & inhibitors | Signal Transduction - genetics | Pyrimidines - pharmacology | CRISPR-Cas Systems - genetics | Xenograft Model Antitumor Assays | Multiprotein Complexes - chemistry | Animals | Signal Transduction - drug effects | Biopsy | Pyrimidines - therapeutic use | Proteomics | Receptors, Antigen, B-Cell - genetics | Mice | Mutation | Toll-Like Receptor 9 - metabolism | Lymphoma, Large B-Cell, Diffuse - genetics | Myeloid Differentiation Factor 88 - metabolism | Lymphomas | Genetic aspects | B cells | Health aspects | TOR protein | Protein kinase C | Toxicity | Genomes | B-cell receptor | Kinases | Gene sequencing | Proteins | Signal transduction | Dependence | Toll-like receptors | CRISPR | NF-κB protein | Therapeutic applications | Autoantigens | Gene expression | Lymphoma | Bruton's tyrosine kinase | TLR9 protein | Signaling | Inhibitors | Lymphocytes B | Cell lines | Bcl-10 protein | MyD88 protein | Syk protein | Scientific imaging | Mass spectrometry | Cancer | Tumors | B-cell lymphoma | Life Sciences | Immunology
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 5/2019, Volume 143, Issue 1, pp. 87 - 93
H3 K27 mutations, most commonly in H3F3A, are common in diffuse midline glioma. The exact frequency of these mutations in adults with gliomas in the midline... 
Neurology | Medicine & Public Health | Glioma | IDH1 | Oncology | Diffuse midline glioma | H3 K27M | ONCOLOGY | CLINICAL NEUROLOGY | Immunohistochemistry | Genetic aspects | Adults | Gliomas | Analysis | Cerebellum | Pons | Mesencephalon | Magnetic resonance imaging | Brain tumors | Mutation | Survival | Patients | Tumors | Clinical Study
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 15_suppl, pp. e14038 - e14038
Journal Article
Oncotarget, ISSN 1949-2553, 2011, Volume 2, Issue 10, pp. 739 - 751
Tumor necrosis factor-α (TNF-α) has been discussed as a potential anticancer agent for many years, however initial enthusiasm about its clinical use as a... 
Chemotherapy | Drug combinations | Oncotarget | TNF | Cancer | Tumor Necrosis Factor-alpha - therapeutic use | Antineoplastic Agents - therapeutic use | Humans | Neoplasms - drug therapy
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. TPS3164 - TPS3164
Journal Article
Science Translational Medicine, ISSN 1946-6234, 02/2014, Volume 6, Issue 224, pp. 224ra24 - 224ra24
The development of noninvasive methods to detect and monitor tumors continues to be a major challenge in oncology. We used digital polymerase chain... 
Humans | Middle Aged | Male | Young Adult | Neoplasm Metastasis | Neoplasms - blood | DNA, Neoplasm - blood | Neoplasms - genetics | Aged, 80 and over | Adult | Female | Aged | Neoplasms - pathology | MEDICINE, RESEARCH & EXPERIMENTAL | CELL BIOLOGY | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 15_suppl, pp. TPS2621 - TPS2621
Journal Article
Journal Article