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Genome-wide association study identifies 74 loci associated with educational attainment
Nature: international weekly journal of science, ISSN 0028-0836, 05/2016, Volume 533, Issue 7604, pp. 539 - 542
textabstractEducational attainment is strongly influenced by social and other environmental factors, but genetic factors are estimated to account for at least...
ACHIEVEMENT | TRAITS | MULTIDISCIPLINARY SCIENCES | HERITABILITY | Genome-Wide Association Study | Gene Expression Regulation - genetics | Humans | Molecular Sequence Annotation | Computational Biology | Fetus - metabolism | United Kingdom | Cognition | Educational Status | Bipolar Disorder - genetics | Gene-Environment Interaction | Brain - metabolism | Schizophrenia - genetics | Polymorphism, Single Nucleotide - genetics | Alzheimer Disease - genetics | Quantitative trait loci | Academic achievement | Genome-wide association studies | Genetic aspects | Observations | Studies | Genomes | Gene expression | Genes | Educational attainment | Meta-analysis | Quantitative Finance | Samhällsvetenskap | Biological Sciences | Social Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
ACHIEVEMENT | TRAITS | MULTIDISCIPLINARY SCIENCES | HERITABILITY | Genome-Wide Association Study | Gene Expression Regulation - genetics | Humans | Molecular Sequence Annotation | Computational Biology | Fetus - metabolism | United Kingdom | Cognition | Educational Status | Bipolar Disorder - genetics | Gene-Environment Interaction | Brain - metabolism | Schizophrenia - genetics | Polymorphism, Single Nucleotide - genetics | Alzheimer Disease - genetics | Quantitative trait loci | Academic achievement | Genome-wide association studies | Genetic aspects | Observations | Studies | Genomes | Gene expression | Genes | Educational attainment | Meta-analysis | Quantitative Finance | Samhällsvetenskap | Biological Sciences | Social Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
Journal Article
Science, ISSN 0036-8075, 6/2013, Volume 340, Issue 6139, pp. 1467 - 1471
A genome-wide association study (GWAS) of educational attainment was conducted in a discovery sample of 101,069 individuals and a replication sample of 25,490....
Medical research | Phenotypes | Psychology | REPORTS | Personality traits | Genetic research | Research facilities | Genetics | Epidemiology | Research universities | Educational attainment | MULTIDISCIPLINARY SCIENCES | LOCI | ENVIRONMENT | Genome-Wide Association Study | Endophenotypes | Humans | Female | Male | Cognition | Educational Status | Polymorphism, Single Nucleotide | Genetic Loci | Multifactorial Inheritance | Academic achievement | Genetic aspects | Research | Single nucleotide polymorphisms | Genetic variation | Genomics | Science education | Medical and Health Sciences | Medicin och hälsovetenskap
Medical research | Phenotypes | Psychology | REPORTS | Personality traits | Genetic research | Research facilities | Genetics | Epidemiology | Research universities | Educational attainment | MULTIDISCIPLINARY SCIENCES | LOCI | ENVIRONMENT | Genome-Wide Association Study | Endophenotypes | Humans | Female | Male | Cognition | Educational Status | Polymorphism, Single Nucleotide | Genetic Loci | Multifactorial Inheritance | Academic achievement | Genetic aspects | Research | Single nucleotide polymorphisms | Genetic variation | Genomics | Science education | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Nature Genetics, ISSN 1061-4036, 2018, Volume 50, Issue 8, pp. 1112 - 1121
Here we conducted a large-scale genetic association analysis of educational attainment in a sample of approximately 1.1 million individuals and identify 1,271...
INTELLIGENCE | HUMAN TRAITS | HUMAN BRAIN | METAANALYSIS | GWAS | STATISTICS | GENETICS & HEREDITY | POPULATIONS | LOCI | MAPPING CAUSAL VARIANTS | HERITABILITY | Humans | Middle Aged | Male | Educational Status | Multifactorial Inheritance | Phenotype | Aged, 80 and over | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Cohort Studies | Cell interaction | Genome-wide association studies | Usage | Analysis | Multifactorial traits | Research | Health education | Brain | Phenotypes | Dosage compensation | Sample size | Cognitive ability | Association analysis | Genomes | Single-nucleotide polymorphism | Gene expression | Estimates | Environmental effects | Educational attainment | Meta-analysis | Consortia | Education | Genetic analysis | Heritability | Basic Medicine | Medical Genetics | Medicinsk genetik | Biological Sciences | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Natural Sciences
INTELLIGENCE | HUMAN TRAITS | HUMAN BRAIN | METAANALYSIS | GWAS | STATISTICS | GENETICS & HEREDITY | POPULATIONS | LOCI | MAPPING CAUSAL VARIANTS | HERITABILITY | Humans | Middle Aged | Male | Educational Status | Multifactorial Inheritance | Phenotype | Aged, 80 and over | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Cohort Studies | Cell interaction | Genome-wide association studies | Usage | Analysis | Multifactorial traits | Research | Health education | Brain | Phenotypes | Dosage compensation | Sample size | Cognitive ability | Association analysis | Genomes | Single-nucleotide polymorphism | Gene expression | Estimates | Environmental effects | Educational attainment | Meta-analysis | Consortia | Education | Genetic analysis | Heritability | Basic Medicine | Medical Genetics | Medicinsk genetik | Biological Sciences | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Natural Sciences
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2098 - 16
textabstractGeneral cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine...
COMMON VARIANTS | METAANALYSIS | REACTION-TIME | PROCESSING SPEED | MULTIDISCIPLINARY SCIENCES | INTELLIGENCE DIFFERENCES | SCHIZOPHRENIA | DCDC2 | DISCOVERY | GENOME-WIDE ASSOCIATION | REVEALS | Multifactorial Inheritance - genetics | Genetic Predisposition to Disease | Humans | Middle Aged | Genetic Loci - genetics | Neurodegenerative Diseases - genetics | Neurodevelopmental Disorders - genetics | Reaction Time - genetics | Young Adult | Mental Disorders - genetics | Adolescent | Aged, 80 and over | Cognition - physiology | Polymorphism, Single Nucleotide - genetics | Adult | Aged | Hypertension | Brain | Cognitive ability | Genomes | Gene expression | Neurodevelopmental disorders | Loci | Consortia | Illnesses | Mathematical analysis | Reaction time | Heritability | Gene loci | Polygenic inheritance | brain cortex | Medical and Health Sciences | Medicin och hälsovetenskap | major clinical study | osteoarthritis | Article | heart infarction | Klinisk medicin | lung cancer | identification method | longevity | grip strength | angina pectoris | genetic correlation | human | major depression | Neurologi | cognition | data set | aged | brain | gene locus | Clinical Medicine | Neurology | genome | vision | genetic analysis | controlled study | response time | adolescent | nervous system disorder | adult | hypertension | gene expression
COMMON VARIANTS | METAANALYSIS | REACTION-TIME | PROCESSING SPEED | MULTIDISCIPLINARY SCIENCES | INTELLIGENCE DIFFERENCES | SCHIZOPHRENIA | DCDC2 | DISCOVERY | GENOME-WIDE ASSOCIATION | REVEALS | Multifactorial Inheritance - genetics | Genetic Predisposition to Disease | Humans | Middle Aged | Genetic Loci - genetics | Neurodegenerative Diseases - genetics | Neurodevelopmental Disorders - genetics | Reaction Time - genetics | Young Adult | Mental Disorders - genetics | Adolescent | Aged, 80 and over | Cognition - physiology | Polymorphism, Single Nucleotide - genetics | Adult | Aged | Hypertension | Brain | Cognitive ability | Genomes | Gene expression | Neurodevelopmental disorders | Loci | Consortia | Illnesses | Mathematical analysis | Reaction time | Heritability | Gene loci | Polygenic inheritance | brain cortex | Medical and Health Sciences | Medicin och hälsovetenskap | major clinical study | osteoarthritis | Article | heart infarction | Klinisk medicin | lung cancer | identification method | longevity | grip strength | angina pectoris | genetic correlation | human | major depression | Neurologi | cognition | data set | aged | brain | gene locus | Clinical Medicine | Neurology | genome | vision | genetic analysis | controlled study | response time | adolescent | nervous system disorder | adult | hypertension | gene expression
Journal Article
PROCEEDINGS OF THE YORKSHIRE GEOLOGICAL SOCIETY, ISSN 0044-0604, 05/2013, Volume 59, pp. 219 - 219
Journal Article
Nature communications, ISSN 2041-1723, 05/2019, Volume 10, Issue 1, pp. 2068 - 5
Christina M. Lill, who contributed to analysis of data, was inadvertently omitted from the author list in the originally published version of this article....
Cognitive ability
Cognitive ability
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2016, Volume 48, Issue 6, pp. 624 - 633
textabstractVery few genetic variants have been associated with depression and neuroticism, likely because of limitations on sample size in previous studies....
PERSONALITY | COMMON VARIANTS | HUMAN HEIGHT | METAANALYSIS | DISEASE | GENETICS & HEREDITY | RISK | MAJOR DEPRESSION | HAPPINESS | HERITABILITY | RESOURCE | Neuroticism | Genome-Wide Association Study | Phenotype | Humans | Bayes Theorem | Anxiety Disorders - genetics | Polymorphism, Single Nucleotide | Depression - genetics | Genome-wide association studies | Genetic variation | Depression, Mental | Genetic aspects | Identification and classification | Methods | Risk factors | Studies | Psychological aspects | Consortia | Social sciences | Quality control | Personality | Genomes | Behavior | Mental depression | Statistics | Epidemiology | Meta-analysis | Quantitative Finance
PERSONALITY | COMMON VARIANTS | HUMAN HEIGHT | METAANALYSIS | DISEASE | GENETICS & HEREDITY | RISK | MAJOR DEPRESSION | HAPPINESS | HERITABILITY | RESOURCE | Neuroticism | Genome-Wide Association Study | Phenotype | Humans | Bayes Theorem | Anxiety Disorders - genetics | Polymorphism, Single Nucleotide | Depression - genetics | Genome-wide association studies | Genetic variation | Depression, Mental | Genetic aspects | Identification and classification | Methods | Risk factors | Studies | Psychological aspects | Consortia | Social sciences | Quality control | Personality | Genomes | Behavior | Mental depression | Statistics | Epidemiology | Meta-analysis | Quantitative Finance
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2018, Volume 50, Issue 10, pp. 1412 - +
High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood...
CARDIOVASCULAR-DISEASE RISK | UK BIOBANK | METAANALYSIS | VARIANTS | RARE | HYPERALDOSTERONISM | COMMON | HEALTH
CARDIOVASCULAR-DISEASE RISK | UK BIOBANK | METAANALYSIS | VARIANTS | RARE | HYPERALDOSTERONISM | COMMON | HEALTH