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Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2015, Volume 10, Issue 12, p. e0144737
Mitochondrial large-conductance Ca2+-sensitive potassium (mBKCa) channels are involved in myocardial ischemic preconditioning. Their role in sildenafil-induced... 
ISCHEMIA-REPERFUSION INJURY | BKCA CHANNELS | SMOOTH-MUSCLE | ACTIVATION | MECHANISM | HUMAN BLADDER | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | CA2+-ACTIVATED K+ CHANNELS | NITRIC-OXIDE | INDUCED RELAXATION | Sildenafil Citrate - pharmacology | Mitochondria, Heart - metabolism | Rats, Wistar | Calcium - metabolism | Myocardial Reperfusion Injury - complications | Body Weight - drug effects | Male | Myocardium - pathology | Cardiotonic Agents - pharmacology | Mitochondria, Heart - drug effects | Myocardial Reperfusion Injury - physiopathology | Myocardial Infarction - complications | Myocardial Reperfusion Injury - pathology | Animals | Cyclic GMP - metabolism | Myocardial Infarction - pathology | Myocardium - metabolism | Potassium Channels, Calcium-Activated - metabolism | Myocardial Infarction - physiopathology | Hemodynamics - drug effects | Carbazoles - pharmacology | Potassium Channel Blockers - pharmacology | Heart | Protein kinase G | Potassium conductance | Kinases | Channels | Mitochondria | Reperfusion | Ischemia | Rodents | Cyclic GMP | Enzyme-linked immunosorbent assay | Calcium channels | Rats | Data processing | Potassium channels | Variance analysis | Calcium (mitochondrial) | Resistance | Protein kinase | Calcium conductance | Pentobarbital | Nitric oxide | Conductance | Sildenafil | Circulatory system | Hemodynamics | In vitro methods and tests | Potassium | Preconditioning
Journal Article
PLoS ONE, ISSN 1932-6203, 2016, Volume 11, Issue 3, p. e0151025
Morphine induces myocardial preconditioning (M-PC) via activation of mitochondrial large conductance Ca2+-sensitive potassium (mKCa) channels. An upstream... 
ISCHEMIA-REPERFUSION INJURY | INFARCT SIZE | ACTIVATION | GENERATING FREE-RADICALS | PATHWAY | TRIGGERS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | RAT-HEART | CARDIOPROTECTION | K-ATP-CHANNELS | Rats, Wistar | Cyclosporine - pharmacology | Male | Mitochondrial Membrane Transport Proteins - physiology | Isoquinolines - pharmacology | Reperfusion | STAT3 Transcription Factor - physiology | Myocardial Infarction - pathology | STAT3 Transcription Factor - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Mitochondrial Membrane Transport Proteins - metabolism | Atractyloside - pharmacology | Cardiotonic Agents - pharmacology | Random Allocation | Sulfonamides - pharmacology | Myocardial Ischemia - pathology | Myocytes, Cardiac - pathology | Cyclic AMP-Dependent Protein Kinases - physiology | Animals | Myocytes, Cardiac - drug effects | Energy Metabolism | Signal Transduction - drug effects | Myocytes, Cardiac - metabolism | Ischemic Preconditioning, Myocardial - methods | Myocardial Infarction - prevention & control | In Vitro Techniques | Morphine - therapeutic use | Prevention | Usage | Transcription factors | Physiological aspects | Morphine | Genetic aspects | Research | Cardiovascular diseases | Risk factors | Protein kinase A | Heart | Intravenous administration | Potassium conductance | Mitochondrial DNA | Proteins | Signal transduction | Ischemia | Bioenergetics | Physiology | Inhibition | Free radicals | Upstream | Rats | Calcium (mitochondrial) | Resistance | Ostomy | Hospitals | Inhibitors | Calcium conductance | Conductance | Anesthesiology | Preconditioning | Mitochondrial permeability transition pore | Cyclosporins | Membrane permeability | Myocardial ischemia | Activation | Kinases | Experiments | Channels | Rodents | Calcium channels | Stat3 protein | Cardiomyocytes | Pharmacology | Potassium channels | Permeability | Signaling | Size reduction | Coronary vessels | In vivo methods and tests | MPTP | Laboratory animals | Potassium | Veins & arteries
Journal Article
ANALYTICAL CHEMISTRY, ISSN 0003-2700, 08/2019, Volume 91, Issue 15, pp. 9490 - 9499
An understanding of what happens to therapeutic antibodies in vivo after subcutaneous injection is of high interest. Therefore, we applied the open flow... 
OXIDATION | QUALITY ATTRIBUTES | CHEMISTRY, ANALYTICAL | MONOCLONAL-ANTIBODY | DEAMIDATION | QUANTIFICATION | Biological properties | Immunoglobulins | Peptides | Antibodies | Workflow | Mass spectroscopy | Injection | Biological samples | Desalination | Streptavidin | Monoclonal antibodies | Beads | Mass spectrometry | Quality management
Journal Article
The Lancet, ISSN 0140-6736, 04/2019, Volume 393, Issue 10180, pp. 1483 - 1485
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 04/2014, Volume 171, Issue 8, pp. 2067 - 2079
Journal Article
PLoS ONE, ISSN 1932-6203, 2018, Volume 13, Issue 11, p. e0207384
Journal Article