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The Journal of rheumatology, ISSN 0315-162X, 04/2019
The genetic component of ankylosing spondylitis (AS) development is ~90%. Of the known heritability, ~20% is explained by HLA-B27, and 113 identified... 
Journal Article
The Journal of Rheumatology, ISSN 0315-162X, 04/2019, p. jrheum.181209
OBJECTIVEThe genetic component of ankylosing spondylitis (AS) development is ~90%. Of the known heritability, ~20% is explained by HLA-B27, and 113 identified... 
Index Medicus
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2016
Abstract Sex is an important determinant of cardiovascular risk, and men generally develop cardiovascular disease (CVD) earlier than women. Increased levels of... 
Cardiovascular
Journal Article
by Lange, Leslie A and Lange, Ethan M and Lange, Christoph and Hu, Youna and Zhang, Qunyuan and Zhang, Ji and Zhang, He and Xue, Chenyi and Schmidt, Ellen M and Tang, Hua and Tang, Zheng-Zheng and Bizon, Chris and Smith, Nicholas L and Smith, Joshua D and Smith, Albert V and Turner, Emily H and Jun, Goo and Kang, Hyun Min and Peloso, Gina and Auer, Paul L and Auer, Paul and Li, Kuo-ping and Li, Mingyao and Li, Yun and Li, Bingshan and Li, Dalin and Flannick, Jason and Fuchsberger, Christian and Gaulton, Kyle and Lindgren, Cecilia and Locke, Adam and Manning, Alisa and Sim, Xueling and Rivas, Manuel A and Holmen, Oddgeir L and Gottesman, Omri and Lu, Yingchang and Ruderfer, Douglas and Stahl, Eli A and Duan, Qing and Durda, Peter and Durda, J. Peter and Jiao, Shuo and Isaacs, Aaron and Hofman, Albert and Bis, Joshua C and Bis, Joshua and Correa, Adolfo and Griswold, Michael E and Jakobsdottir, Johanna and Schreiner, Pamela and Schreiner, Pamela J and Feitosa, Mary F and Huffman, Jennifer E and Crosby, Jacy and Wassel, Chrstina L and Wassel, Christina L and Do, Ron and Franceschini, Nora and Martin, Lisa and Martin, Lisa W and Martin, Thomas R and Robinson, Jennifer G and Assimes, Themistocles L and Crosslin, David R and Rosenthal, Elisabeth A and Tsai, Michael Y and Tsai, Michael and Rieder, Mark J and Farlow, Deborah N and Folsom, Aaron R and Lumley, Thomas and Fox, Ervin R and Fox, Caroline S and Fox, P. Keolu and Fox, Ervin and Carlson, Christopher S and Peters, Ulrike and Jackson, Rebecca D and Jackson, Rebecca and van Duijn, Cornelia M and Uitterlinden, André G and Levy, Daniel and Rotter, Jerome I and Taylor, Herman A and Taylor, Kira C and Taylor, Kent and Gudnason, Vilmundur and Siscovick, David S and Fornage, Myriam and Borecki, Ingrid B and Hayward, Caroline and Rudan, Igor and Chen, Wei-Min and Chen, Y. Eugene and Chen, Donna T and Chen, Ida Y and Bottinger, Erwin P and Loos, Ruth J.F and Sætrom, Pål and ... and NHLBI Grand Opportunity Exome Sequ and NHLBI Grand Opportunity Exome Sequencing Project and Genomik, diabetes och endokrinologi and Lund University and Genomics, Diabetes and Endocrinology and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 233 - 245
Journal Article
by McCarthy, Shane and Das, Sayantan and Kretzschmar, Warren and Delaneau, Olivier and Wood, Anew R and Teumer, Alexander and Kang, Hyun Min and Fuchsberger, Christian and Danecek, Petr and Sharp, Kevin and Luo, Yang and Sidorel, Carlo and Kwong, Alan and Timpson, Nicholas and Koskinen, Seppo and Vrieze, Scott and Scott, Laura J and Zhang, He and Mahajan, Anubha and Veldink, Jan and Peters, Ulrike and Pato, Carlos and van Duijn, Cornelia M and Gillies, Christopher E and Gandin, Ilaria and Mezzavilla, Massimo and Gilly, Arthur and Cocca, Massimiliano and Traglia, Michela and Angius, Anea and Barrett, Jeffrey C and Boomsma, Dorrett and Branham, Kari and Breen, Gerome and Brummett, Chad M and Busonero, Fabio and Campbell, Harry and Chan, Anew and Che, Sai and Chew, Emily and Collins, Francis S and Corbin, Laura J and Smith, George Davey and Dedoussis, George and Dorr, Marcus and Farmaki, Aliki-Eleni and Ferrucci, Luigi and Forer, Lukas and Fraser, Ross M and Gabriel, Stacey and Levy, Shawn and Groop, Leif and Harrison, Tabitha and Hattersley, Anew and Holmen, Oddgeir L and Hveem, Kristian and Kretzler, Matthias and Lee, James C and McGue, Matt and Meitinger, Thomas and Melzer, David and Min, Josine L and Mohlke, Karen L and Vincent, John B and Nauck, Matthias and Nickerson, Deborah and Palotie, Aarno and Pato, Michele and Pirastu, Nicola and McInnis, Melvin and Richards, J. Brent and Sala, Cinzia and Salomaa, Veikko and Schlessinger, David and Schoenherr, Sebastian and Slagboom, P. Eline and Small, Kerrin and Spector, Timothy and Stambolian, Dwight and Tuke, Marcus and Tuomilehto, Jaakko and van den Berg, Leonard H and Van Rheenen, Wouter and Volker, Uwe and Wijmenga, Cisca and Toniolo, Daniela and Zeggini, Eleftheria and Gasparini, Paolo and Sampson, Matthew G and Wilson, James F and Frayling, Timothy and de Bakker, Paul I. W and Swertz, Morris A and McCarroll, Steven and Kooperberg, Charles and Dekker, Annelot and Altshuler, David and Willer, Cristen and Iacono, William and Ripatti, Samuli and ... and Haplotype Reference Consortium and the Haplotype Reference Consortium and Genomik, diabetes och endokrinologi and Lund University and Genomics, Diabetes and Endocrinology and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
Nature Genetics, ISSN 1061-4036, 10/2016, Volume 48, Issue 10, pp. 1279 - 1283
Journal Article
by Mahajan, Anubha and Go, Min Jin and Zhang, Weihua and Below, Jennifer E and Gaulton, Kyle J and Ferreira, Teresa and Horikoshi, Momoko and Johnson, Anew D and Ng, Maggie C. Y and Prokopenko, Inga and Saleheen, Danish and Wang, Xu and Zeggini, Eleftheria and Abecasis, Goncalo R and Adair, Linda S and Almgren, Peter and Atalay, Mustafa and Aung, Tin and Baldassarre, Damiano and Balkau, Beverley and Bao, Yuqian and Barnett, Anthony H and Barroso, Ines and Basit, Abdul and Been, Latonya F and Beilby, John and Bell, Graeme I and Benediktsson, Rafn and Bergman, Richard N and Boehm, Bernhard O and Boerwinkle, Eric and Bonnycastle, Lori L and Burtt, Noël and Cai, Qiuyin and Campbell, Harry and Carey, Jason and Cauchi, Stephane and Caulfield, Mark and Chan, Juliana C. N and Chang, Li-Ching and Chang, Tien-Jyun and Chang, Yi-Cheng and Charpentier, Guillaume and Chen, Chien-Hsiun and Chen, Han and Chen, Yuan-Tsong and Chia, Kee-Seng and Chidambaram, Manickam and Chines, Peter S and Cho, Nam H and Cho, Young Min and Chuang, Lee-Ming and Collins, Francis S and Cornelis, Marilyn C and Couper, David J and Crenshaw, Anew T and van Dam, Rob M and Danesh, John and Das, Debashish and de Faire, Ulf and Dedoussis, George and Deloukas, Panos and Dimas, Antigone S and Dina, Christian and Doney, Alex S. F and Donnelly, Peter J and Dorkhan, Mozhgan and van Duijn, Cornelia and Dupuis, Josée and Edkins, Sarah and Elliott, Paul and Emilsson, Valur and Erbel, Raimund and Eriksson, Johan G and Escobedo, Jorge and Esko, Tonu and Eury, Elodie and Florez, Jose C and Fontanillas, Pierre and Forouhi, Nita G and Forsen, Tom and Fox, Caroline and Fraser, Ross M and Frayling, Timothy M and Froguel, Philippe and Frossard, Philippe and Gao, Yutang and Gertow, Karl and Gieger, Christian and Gigante, Bruna and Grallert, Harald and Grant, George B and Groop, Leif C and Groves, Christopher J and Grundberg, Elin and Guiducci, Candace and Hamsten, Anders and Han, Bok-Ghee and Hara, Kazuo and Hassanali, Neelam and ... and South Asian Type Diabet SAT2D Cons and DIAbet Genetics Replication & Meta and Mexican Amer Type 2 Diabet MAT2D C and Asian Genetic Epidemiology Network and Type 2 Diabet Genetic Exploration and South Asian Type 2 Diabetes (SAT2D) Consortium and Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium and Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium and DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium and Mexican American Type 2 Diabetes (MAT2D) Consortium and Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Molekylär medicin and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 3, pp. 234 - 244
Journal Article
by Webb, Thomas R., PhD and Erdmann, Jeanette, PhD and Stirrups, Kathleen E., PhD and Stitziel, Nathan O., MD, PhD and Masca, Nicholas G.D., PhD and Jansen, Henning, MD and Kanoni, Stavroula, PhD and Nelson, Christopher P., PhD and Ferrario, Paola G., PhD and König, Inke R., PhD and Eicher, John D., PhD and Johnson, Andrew D., PhD and Hamby, Stephen E., PhD and Betsholtz, Christer, PhD and Ruusalepp, Arno, MD, PhD and Franzén, Oscar, PhD and Schadt, Eric E., MD, PhD and Björkegren, Johan L.M., MD, PhD and Weeke, Peter E., MD, PhD and Auer, Paul L., PhD and Schick, Ursula M., PhD and Lu, Yingchang, MD, PhD and Zhang, He, PhD and Dube, Marie-Pierre, PhD and Goel, Anuj, MSc and Farrall, Martin, MD and Peloso, Gina M., PhD and Won, Hong-Hee, PhD and Do, Ron, PhD and van Iperen, Erik, MSc and Kruppa, Jochen, PhD and Mahajan, Anubha, PhD and Scott, Robert A., PhD and Willenborg, Christina, PhD and Braund, Peter S., PhD and van Capelleveen, Julian C., MD and Doney, Alex S.F., MD, PhD and Donnelly, Louise A., PhD and Asselta, Rosanna, PhD and Merlini, Pier A., MD and Duga, Stefano, PhD and Marziliano, Nicola, PhD and Denny, Josh C., MD, MS and Shaffer, Christian, BS and El-Mokhtari, Nour Eddine, MD and Franke, Andre, PhD and Heilmann, Stefanie, PhD and Hengstenberg, Christian, MD and Hoffmann, Per, PhD and Holmen, Oddgeir L., MD and Hveem, Kristian, MD, PhD and Jansson, Jan-Håkan, MD, PhD and Jöckel, Karl-Heinz, PhD and Kessler, Thorsten, MD and Kriebel, Jennifer, PhD and Laugwitz, Karl L., MD and Marouli, Eirini, MSc and Martinelli, Nicola, MD, PhD and McCarthy, Mark I., MD and Van Zuydam, Natalie R., PhD and Meisinger, Christa, MD, MPH and Esko, Tõnu, PhD and Mihailov, Evelin, MSc and Escher, Stefan A., PhD and Alver, Maris, MSc and Moebus, Susanne, PhD and Morris, Andrew D., MD and Virtamo, Jarma, MD, PhD and Nikpay, Majid, PhD and Olivieri, Oliviero, MD and Provost, Sylvie, MSc and AlQarawi, Alaa, BSc and Robertson, Neil R., MSc and Akinsansya, Karen O., PhD and Reilly, Dermot F., PhD and Vogt, Thomas F., PhD and Yin, Wu, PhD and Asselbergs, Folkert W., MD, PhD and Kooperberg, Charles, PhD and Jackson, Rebecca D., MD and Stahl, Eli, PhD and Müller-Nurasyid, Martina, PhD and Strauch, Konstantin, PhD and Varga, Tibor V., PhD and Waldenberger, Melanie, PhD and Zeng, Lingyao, MSc and Chowdhury, Rajiv, MD, PhD and Salomaa, Veikko, MD, PhD and Ford, Ian, PhD and Jukema, J. Wouter, MD, PhD and Amouyel, Philippe, MD, PhD and Kontto, Jukka, MSSc and Nordestgaard, Børge G., MD, DMSc and Ferrières, Jean, MD and Saleheen, Danish, MBBS, PhD and Sattar, Naveed, PhD and Surendran, Praveen, PhD and Wagner, Aline, MD, PhD and Young, Robin, PhD and Howson, Joanna M.M., PhD and ... and Wellcome Trust Case Control and MORGAM Investigators and Myocardial Infarction Genetics and Wellcome Trust Case Control Consortium and Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Medicin
Journal of the American College of Cardiology, ISSN 0735-1097, 2017, Volume 69, Issue 7, pp. 823 - 836
Abstract Background Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show... 
Cardiovascular | Internal Medicine | expression quantitative trait loci | genetics | genome-wide association | single nucleotide polymorphism | cholesteryl ester transfer protein | SR-BI | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | CETP MASS | SUSCEPTIBILITY | RISK | PHOSPHOLIPASE A | VARIANT | SCAVENGER RECEPTOR | ABDOMINAL AORTIC-ANEURYSM | Genome-Wide Association Study | Gene Frequency | Humans | Coronary Artery Disease - genetics | Female | Male | Coronary Artery Disease - epidemiology | Genetic Pleiotropy | Polymorphism, Single Nucleotide | Genetic Loci | Odds Ratio | Case-Control Studies | Coronary heart disease | Analysis | Genealogy | Cardiovascular disease | Genomes | Metabolism | Gene expression | Blood | Risk factors | Studies | Celiac disease | Lipoproteins | Coronary vessels | Rheumatoid arthritis | Quality control | Calcification | Diabetes | Bioinformatics | Index Medicus | Abridged Index Medicus | LD, linkage disequilibrium | CETP, cholesteryl ester transfer protein | eQTL, expression quantitative trait locus | CAD, coronary artery disease | GWAS, genome-wide association study | BMI, body mass index | SNP, single nucleotide polymorphism | HDL, high-density lipoprotein | LDL, low-density lipoprotein | Original Investigation | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Kardiologi | Medical Genetics | Medicinsk genetik | Clinical Medicine | Cardiac and Cardiovascular Systems | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Marouli, Eirini and Graff, Mariaelisa and Medina-Gomez, Carolina and Lo, Ken Sin and Wood, Anew R and Kjaer, Troels R and Fine, Rebecca S and Lu, Yingchang and Schurmann, Claudia and Highland, Heather M and Rüeger, Sina and Thorleifsson, Gudmar and Justice, Anne E and Lamparter, David and Stirrups, Kathleen E and Turcot, Valérie and Young, Kristin L and Winkler, Thomas W and Esko, Tõnu and Karaderi, Tugce and Locke, Adam E and Masca, Nicholas G. D and Ng, Maggie C. Y and Mudgal, Poorva and Rivas, Manuel A and Vedantam, Sailaja and Mahajan, Anubha and Guo, Xiuqing and Abecasis, Goncalo and Aben, Katja K and Adair, Linda S and Alam, Dewan S and Albrecht, Eva and Allin, Kristine H and Allison, Matthew and Amouyel, Philippe and Appel, Emil V and Arveiler, Dominique and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Banas, Bernhard and Bang, Lia E and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bonnycastle, Lori L and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Burt, Amber A and Butterworth, Adam S and Carey, David J and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Cocca, Massimiliano and Collins, Francis S and Cook, James P and Corley, Janie and Galbany, Jordi Corominas and Cox, Amanda J and Cuellar-Partida, Gabriel and Danesh, John and Davies, Gail and de Bakker, Paul I. W and de Borst, Gert J and de Denus, Simon and de Groot, Mark C. H and de Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and den Hollander, Anneke I and Dennis, Joe G and Di Angelantonio, Emanuele and nos, Fotios and Du, Mengmeng and Dunning, Alison M and Easton, Douglas F and Ebeling, Tapani and Edwards, Todd L and Ellinor, Patrick T and Elliott, Paul and Evangelou, Evangelos and Farmaki, Aliki-Eleni and Faul, Jessica D and ... and EPIC-CVD Consortium and GoT2D Genes Consortium and MAGIC Investigators and Global Lipids Genetics Consortium and EPIC-InterAct Consortium and ReproGen Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium and The EPIC-InterAct Consortium and CHD Exome+ Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2017, Volume 542, Issue 7640, pp. 186 - 190
Journal Article
by Gaulton, Kyle J and Ferreira, Teresa and Lee, Yeji and Raimondo, Anne and Mägi, Reedik and Reschen, Michael E and Mahajan, Anubha and Locke, Adam and Rayner, N. William and Robertson, Neil and Scott, Robert A and Prokopenko, Inga and Scott, Laura J and Green, Todd and Sparso, Thomas and Thuillier, Dorothee and Yengo, Loic and Grallert, Harald and Wahl, Simone and Frånberg, Mattias and Strawbridge, Rona J and Kestler, Hans and Chheda, Himanshu and Eisele, Lewin and Gustafsson, Stefan and Steinthorsdottir, Valgerdur and Thorleifsson, Gudmar and Qi, Lu and Karssen, Lennart C and van Leeuwen, Elisabeth M and Willems, Sara M and Li, Man and Chen, Han and Fuchsberger, Christian and Kwan, Phoenix and Ma, Clement and Linderman, Michael and Lu, Yingchang and Thomsen, Soren K and Rundle, Jana K and Beer, Nicola L and van de Bunt, Martijn and Chalisey, Anil and Kang, Hyun Min and Voight, Benjamin F and Abecasis, Gonçalo R and Almgren, Peter and Baldassarre, Damiano and Balkau, Beverley and Benediktsson, Rafn and Blüher, Matthias and Boeing, Heiner and Bonnycastle, Lori L and Bottinger, Erwin P and Burtt, Noël P and Carey, Jason and Charpentier, Guillaume and Chines, Peter S and Cornelis, Marilyn C and Couper, David J and Crenshaw, Anew T and van Dam, Rob M and Doney, Alex S. F and Dorkhan, Mozhgan and Edkins, Sarah and Eriksson, Johan G and Esko, Tonu and Eury, Elodie and Fadista, João and Flannick, Jason and Fontanillas, Pierre and Fox, Caroline and Franks, Paul W and Gertow, Karl and Gieger, Christian and Gigante, Bruna and Gottesman, Omri and Grant, George B and Grarup, Niels and Groves, Christopher J and Hassinen, Maija and Have, Christian T and Herder, Christian and Holmen, Oddgeir L and Hreidarsson, Astradur B and Humphries, Steve E and Hunter, David J and Jackson, Anne U and Jonsson, Anna and Jørgensen, Marit E and Jørgensen, Torben and Kao, Wen-Hong L and Kerrison, Nicola D and Kinnunen, Leena and Klopp, Norman and Kong, Augustine and Kovacs, Peter and Kraft, Peter and Kravic, Jasmina and Langford, Cordelia and ... and DIAbet Genetics Replication Meta-A and the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium and Numerisk analys och datalogi (NADA) and Naturvetenskapliga fakulteten and Stockholms universitet and Science for Life Laboratory (SciLifeLab)
Nature genetics, ISSN 1061-4036, 2015, Volume 47, Issue 12, pp. 1415 - +
Journal Article