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The New England Journal of Medicine, ISSN 0028-4793, 03/2019, Volume 380, Issue 11, pp. 1076 - 1079
Current tools in the field of human genetics can reliably estimate both the intended and the adverse effects of modifying a therapeutic target to guide the... 
MEDICINE, GENERAL & INTERNAL | Human Genetics | Cholesterol, LDL | Dicarboxylic Acids | Fatty Acids | Drug Development | Humans | Drugs | Decision making | Therapeutic applications | Cardiovascular disease | Drug development | Low density lipoprotein | Cholesterol | Confidence intervals | Side effects | Acids | Genetics | Diabetes | Health risk assessment | Statins | Index Medicus | Abridged Index Medicus
Journal Article
European Heart Journal, ISSN 0195-668X, 07/2019
Journal Article
Nature Reviews Cardiology, ISSN 1759-5002, 04/2019, Volume 16, Issue 4, pp. 197 - 198
LDL cholesterol is an important contributor to the risk of coronary heart disease, and its measurement is central to evaluating the effects of lipid-modifying... 
CARDIAC & CARDIOVASCULAR SYSTEMS | Measurement | Complications and side effects | Hypercholesterolemia | Cholesterol, LDL | Development and progression | Health aspects | Coronary heart disease | Risk factors | Cardiovascular disease | Low density lipoprotein | Statins | Cholesterol
Journal Article
Clinical Chemistry, ISSN 0009-9147, 03/2019, Volume 65, Issue 3, pp. 363 - 366
[...]disease-GRS associations with a biomarker may represent a consequence of disease, akin to the conventional epidemiological phenomenon of "reverse... 
MEDICAL LABORATORY TECHNOLOGY | Phenotypes | Prostate-specific antigen | Phenotypic variations | Cardiovascular disease | Epidemiology | Studies | Disease prevention | Genetic variance | Pleiotropy | Biomarkers | Bioindicators | Prostate cancer | Prostate | Genotypes | Cancer
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2019, Volume 73, Issue 4, pp. 477 - 487
Cholesteryl ester transfer protein (CETP) facilitates exchange of triglycerides and cholesteryl ester between high-density lipoprotein (HDL) and apolipoprotein... 
cardiovascular disease | CETP | CETP inhibitor | randomized trial | Mendelian randomization | LDL cholesterol | HDL cholesterol
Journal Article
CLINICAL CHEMISTRY, ISSN 0009-9147, 08/2019, Volume 65, Issue 8, pp. 1042 - 1050
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2/2019, Volume 73, Issue 4, pp. 477 - 487
Journal Article
International Journal of Epidemiology, ISSN 0300-5771, 06/2019, Volume 48, Issue 3, pp. 830 - 833
Journal Article
by Swerdlow, Daniel I, Dr and Preiss, David, Dr and Kuchenbaecker, Karoline B, MSc and Holmes, Michael V, PhD and Engmann, Jorgen E L, MSc and Shah, Tina, PhD and Sofat, Reecha, MD and Stender, Stefan, MD and Johnson, Paul C D, PhD and Scott, Robert A, PhD and Leusink, Maarten, MSc and Verweij, Niek, MD and Sharp, Stephen J, MSc and Guo, Yiran, PhD and Giambartolomei, Claudia, MSc and Chung, Christina, MSc and Peasey, Anne, PhD and Amuzu, Antoinette, MSc and Li, KaWah, MSc and Palmen, Jutta, MSc and Howard, Philip, MSc and Cooper, Jackie A, MSc and Drenos, Fotios, PhD and Li, Yun R, BSc and Lowe, Gordon, Prof and Gallacher, John, PhD and Stewart, Marlene C W, PhD and Tzoulaki, Ioanna, PhD and Buxbaum, Sarah G, PhD and van der A, Daphne L, PhD and Forouhi, Nita G, MRCP and Onland-Moret, N Charlotte, PhD and van der Schouw, Yvonne T, Prof and Schnabel, Renate B, MD and Hubacek, Jaroslav A, PhD and Kubinova, Ruzena, MD and Baceviciene, Migle, MD and Tamosiunas, Abdonas, Prof and Pajak, Andrzej, Prof and Topor-Madry, Romanvan, MD and Stepaniak, Urszula, PhD and Malyutina, Sofia, Prof and Baldassarre, Damiano, PhD and Sennblad, Bengt, PhD and Tremoli, Elena, Prof and de Faire, Ulf, Prof and Veglia, Fabrizio, PhD and Ford, Ian, Prof and Jukema, J Wouter, Prof and Westendorp, Rudi G J, Prof and de Borst, Gert Jan, MD and de Jong, Pim A, MD and Algra, Ale, Prof and Spiering, Wilko, MD and der Zee, Anke H Maitland-van, PhD and Klungel, Olaf H, PharmD and de Boer, Anthonius, Prof and Doevendans, Pieter A, Prof and Eaton, Charles B, Prof and Robinson, Jennifer G, Prof and Duggan, David, PhD and Kjekshus, John, Prof and Downs, John R, MD and Gotto, Antonio M, MD and Keech, Anthony C, MD and Marchioli, Roberto, MD and Tognoni, Gianni, MD and Sever, Peter S, Prof and Poulter, Neil R, Prof and Waters, David D, MD and Pedersen, Terje R, MD and Amarenco, Pierre, MD and Nakamura, Haruo, MD and McMurray, John J V, Prof and Lewsey, James D, PhD and Chasman, Daniel I, PhD and Ridker, Paul M, MD and Maggioni, Aldo P, Prof and Tavazzi, Luigi, Prof and Ray, Kausik K, Prof and Seshasai, Sreenivasa Rao Kondapally, MD and Manson, JoAnn E, Prof and Price, Jackie F, MD and Whincup, Peter H, Prof and Morris, Richard W, Prof and Lawlor, Debbie A, Prof and Smith, George Davey, Prof and Ben-Shlomo, Yoav, Prof and Schreiner, Pamela J, Prof and Fornage, Myriam, Prof and Siscovick, David S, Prof and Cushman, Mary, MD and Kumari, Meena, PhD and Wareham, Nick J, Prof and Verschuren, W M Monique, PhD and Redline, Susan, Prof and Patel, Sanjay R, MD and Whittaker, John C, Prof and Hamsten, Anders, Prof and Delaney, Joseph A, PhD and ... and MAGIC Consortium and InterAct Consortium and DIAGRAM Consortium
The Lancet, ISSN 0140-6736, 01/2015, Volume 385, Issue 9965, pp. 351 - 361
Journal Article
The Lancet Diabetes & Endocrinology, ISSN 2213-8587, 12/2018, Volume 6, Issue 12, pp. 922 - 922
Journal Article
International journal of epidemiology, ISSN 0300-5771, 01/2019, Volume 48, Issue 3, pp. 978 - 993
Quantitative molecular data from urine are rare in epidemiology and genetics. NMR spectroscopy could provide these data in high throughput, and it has already... 
Index Medicus
Journal Article
Atherosclerosis, ISSN 0021-9150, 09/2016, Volume 254, p. 35
BACKGROUND AND AIMS: Type 2 diabetes (T2D), low-density lipoprotein-cholesterol (LDL-c), body mass index (BMI), blood pressure and smoking are established risk... 
Journal Article
American Journal of Kidney Diseases, ISSN 0272-6386, 02/2018, Volume 71, Issue 2, pp. 149 - 153
Journal Article
Lancet, The, ISSN 0140-6736, 2011, Volume 378, Issue 9791, pp. 584 - 594
Journal Article