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Biochemical Journal, ISSN 0264-6021, 06/2005, Volume 388, Issue 2, pp. 393 - 406
The Grb proteins (growth factor receptor-bound proteins) Grb7, Grb10 and Grb14 constitute a family of structurally related multidomain adapters with diverse... 
Cell signalling | Type II diabetes | Tyrosine kinase | Cell growth | Adapter protein | adapter protein | SRC HOMOLOGY 2 | SILVER-RUSSELL-SYNDROME | CANDIDATE GENE REGION | GROWTH-FACTOR-RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | tyrosine kinase | cell growth | ADAPTER PROTEIN GRB10 | SH2 DOMAIN PROTEINS | cell signalling | PLECKSTRIN HOMOLOGY | FOCAL ADHESION KINASE | FACTOR-I RECEPTOR | Protein Structure, Tertiary | Proteins - physiology | Genetic Predisposition to Disease | Insulin - physiology | Humans | Gene Expression Regulation | Structure-Activity Relationship | Amino Acid Motifs | Animals | GRB10 Adaptor Protein | Protein Isoforms | Protein Conformation | Proteins - chemistry | PI3K, phosphoinositide 3-kinase | SRS, Silver–Russell syndrome | MEK1, MAP kinase | BPS, between the PH and SH2 (domains) | Review | IGFR, IGF-I receptor | IRS, IR substrate | PDGF(-BB), platelet-derived growth factor(-BB) | UTR, untranslated region | RA, Ras-association | VEGF(R2), vascular endothelial growth factor (receptor 2) | Meg, maternally expressed gene | GIGYF protein, Grb10 interacting GYF protein | IUP, intrinsically unstructured protein | TZD, thiazolidinedione | ZIP, PKCζ-interacting protein | Erk, extracellular-signal-regulated kinase | IR, insulin receptor | Grb, growth factor receptor-bound protein | FGF(R), fibroblast growth factor receptor | GST, glutathione S-transferase | FAK, focal adhesion kinase | Shc, Src homology collagen | EGF(R), epidermal growth factor (receptor) | GM, Grbs and Mig | PDK-1, 3′-phosphoinositide-dependent kinase 1 | siRNA, small interfering RNA | PH, pleckstrin homology | PKCζ, protein kinase Cζ | APS, adapter protein with PH and SH2 domains | SH2, Src homology 2 | IGF-I, type I insulin-like growth factor | GK, Goto-Kakizaki | (m)UPD7, (maternal) uniparental disomy of chromosome 7 | MAPK, mitogen-activated protein kinase | Erk kinase | Nedd4, neuronal precursor cell-expressed developmentally down-regulated | PTP, protein tyrosine phosphatase
Journal Article
Endocrinology, ISSN 0013-7227, 03/2018, Volume 159, Issue 3, pp. 1339 - 1351
Grb10 is an adaptor-type signaling protein most highly expressed in tissues involved in insulin action and glucose metabolism, such as muscle, pancreas, and... 
HYPERTROPHY | DISRUPTION | PHOSPHORYLATION | INSULIN-RESISTANCE | IN-VIVO | ENDOCRINOLOGY & METABOLISM | SENSITIVITY | RECEPTOR | EXPRESSION | SKELETAL ACTIN GENE | TRANSGENIC MICE | Phenotypes | Muscles | Homeostasis | AKT protein | Recombinase | Glucose | Metabolism | Insulin | Ablation | Cre recombinase | Flox | Proteins | Glucose metabolism | Signaling | Clonal deletion | Actin | Deletion | Metabolic pathways | Pancreas
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 08/2009, Volume 94, Issue 8, pp. 3101 - 3101
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 08/2009, Volume 94, Issue 8, pp. 3101 - 3101
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 11/2014, Volume 229, Issue 11, pp. 1753 - 1764
Grb10 is an intracellular adaptor protein which binds directly to several growth factor receptors, including those for insulin and insulin‐like growth factor... 
INSULIN-RECEPTOR | PHYSIOLOGY | ADHESION MOLECULE | GENE | MYOGENESIS | SATELLITE CELLS | MICE | DNA-SYNTHESIS | EXPRESSION | ADULT SKELETAL-MUSCLE | GROWTH-FACTOR-I | CELL BIOLOGY | Muscle Cells - drug effects | Protein Transport - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | Muscle Fibers, Skeletal - metabolism | RNA, Messenger - metabolism | Cell Differentiation - genetics | Myoblasts, Skeletal - cytology | Gene Deletion | GRB10 Adaptor Protein - metabolism | Cell Membrane - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cell Membrane - drug effects | Biomarkers - metabolism | CD56 Antigen - metabolism | Insulin - pharmacology | Cell Separation | Mice, Inbred C57BL | RNA, Messenger - genetics | Satellite Cells, Skeletal Muscle - cytology | Cells, Cultured | Muscle Cells - metabolism | Satellite Cells, Skeletal Muscle - metabolism | Myoblasts, Skeletal - enzymology | GRB10 Adaptor Protein - genetics | Muscle Cells - cytology | Gene Expression Regulation - drug effects | Satellite Cells, Skeletal Muscle - drug effects | Animals | MAP Kinase Signaling System - drug effects | Cell Differentiation - drug effects | Glucose - metabolism | Cell Proliferation - drug effects | Mice | Cell Cycle - drug effects | Myoblasts, Skeletal - drug effects | Myogenin - metabolism | Glucose metabolism | Physiological aspects | Cell membranes | Glucose | Cell differentiation | Dextrose | Protein binding | Index Medicus
Journal Article
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 08/2007, Volume 27, Issue 16, pp. 5871 - 5886
The Grb10 adapter protein is capable of interacting with a variety of receptor tyrosine kinases, including, notably, the insulin receptor. Biochemical and cell... 
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 09/2009, Volume 23, Issue 9, pp. 1406 - 1414
Growth factor receptor bound (Grb)10 and Grb14 are closely related adaptor proteins that bind directly to the insulin receptor (IR) and regulate... 
ADAPTER PROTEIN GRB10 | TRANSLOCATION | DISRUPTION | INHIBITION | GENE | IN-VIVO | ENDOCRINOLOGY & METABOLISM | RESISTANCE | SENSITIVITY | RECEPTOR | DEGRADATION
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