1999, JAERI-data/code, Volume 99-002., iv, 59
Book
Nature Genetics, ISSN 1061-4036, 04/2012, Volume 44, Issue 4, pp. 376 - 378
By exome sequencing, we found de novo SMARCB1 mutations in two of five individuals with typical Coffin-Siris syndrome (CSS), a rare autosomal dominant anomaly...
SCHWANNOMATOSIS | SMARCB1 | GENE | CANCER | GENETICS & HEREDITY | Face - abnormalities | Humans | Micrognathism - genetics | Cells, Cultured | Male | DNA Copy Number Variations - genetics | Mutation, Missense | Neck - abnormalities | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Sequence Analysis, DNA | Chromosomal Proteins, Non-Histone - genetics | Intellectual Disability - genetics | Exome | SMARCB1 Protein | Hand Deformities, Congenital - genetics | Female | Nuclear Proteins - genetics | DNA Helicases - genetics | Abnormalities, Multiple - genetics | Physiological aspects | Chromatin | Genetic aspects | Research | Gene mutations | Coffin-Siris syndrome | Proteins | Science | Genetics | Mutation
SCHWANNOMATOSIS | SMARCB1 | GENE | CANCER | GENETICS & HEREDITY | Face - abnormalities | Humans | Micrognathism - genetics | Cells, Cultured | Male | DNA Copy Number Variations - genetics | Mutation, Missense | Neck - abnormalities | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Sequence Analysis, DNA | Chromosomal Proteins, Non-Histone - genetics | Intellectual Disability - genetics | Exome | SMARCB1 Protein | Hand Deformities, Congenital - genetics | Female | Nuclear Proteins - genetics | DNA Helicases - genetics | Abnormalities, Multiple - genetics | Physiological aspects | Chromatin | Genetic aspects | Research | Gene mutations | Coffin-Siris syndrome | Proteins | Science | Genetics | Mutation
Journal Article
Macromolecular Rapid Communications, ISSN 1022-1336, 12/2019, Volume 40, Issue 23, pp. 1900464 - n/a
Stimuli‐responsive smart materials are a key to the realization of next‐generation medical technologies. Among them, the temperature‐responsive polymer...
thermoresponsive polymers | fast cell detachment | volume expansion | microfibers
thermoresponsive polymers | fast cell detachment | volume expansion | microfibers
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2013, Volume 36, Issue 2, pp. 215 - 221
Photodynamic therapy (PDT) induces selective cell death of neoplastic tissue and connecting vasculature by combining photosensitizers with light. Here we...
talaporfin sodium | apoptosis | glioma | necrosis | photodynamic therapy | Photodynamic therapy | Glioma | Talaporfin sodium | Apoptosis | Necrosis | PATHWAYS | ACTIVATION | MOUSE-TUMOR MODEL | LYSOSOMAL PHOTODAMAGE | PHARMACOLOGY & PHARMACY | L-ASPARTYL CHLORIN-E6 | CANCER | Porphyrins - administration & dosage | Cytochromes c - metabolism | Humans | Brain Neoplasms - pathology | Caspase 3 - metabolism | Necrosis - metabolism | Mitochondria - metabolism | Antineoplastic Agents - administration & dosage | Mitochondria - drug effects | Brain Neoplasms - drug therapy | Necrosis - pathology | Photochemotherapy | Brain Neoplasms - metabolism | Glioma - metabolism | Necrosis - chemically induced | Photosensitizing Agents - administration & dosage | DNA Fragmentation | Glioma - pathology | Cell Line, Tumor | Cell Death - drug effects | Glioma - drug therapy
talaporfin sodium | apoptosis | glioma | necrosis | photodynamic therapy | Photodynamic therapy | Glioma | Talaporfin sodium | Apoptosis | Necrosis | PATHWAYS | ACTIVATION | MOUSE-TUMOR MODEL | LYSOSOMAL PHOTODAMAGE | PHARMACOLOGY & PHARMACY | L-ASPARTYL CHLORIN-E6 | CANCER | Porphyrins - administration & dosage | Cytochromes c - metabolism | Humans | Brain Neoplasms - pathology | Caspase 3 - metabolism | Necrosis - metabolism | Mitochondria - metabolism | Antineoplastic Agents - administration & dosage | Mitochondria - drug effects | Brain Neoplasms - drug therapy | Necrosis - pathology | Photochemotherapy | Brain Neoplasms - metabolism | Glioma - metabolism | Necrosis - chemically induced | Photosensitizing Agents - administration & dosage | DNA Fragmentation | Glioma - pathology | Cell Line, Tumor | Cell Death - drug effects | Glioma - drug therapy
Journal Article
American Journal of Medical Genetics Part A, ISSN 1552-4825, 06/2013, Volume 161, Issue 6, pp. 1221 - 1237
Mutations in the components of the SWItch/sucrose nonfermentable (SWI/SNF)‐like chromatin remodeling complex have recently been reported to cause Coffin–Siris...
SMARCE1 | SMARCB1 | intellectual disability (ID) | SWI/SNF complex | Coffin–Siris syndrome | ARID1A | SMARCA2 | ARID1B | Nicolaides–Baraitser syndrome | SMARCA4 | Intellectual disability (ID) | Coffin-Siris syndrome | Nicolaides-Baraitser syndrome | DELINEATION | CHROMATIN-REMODELING COMPLEX | GENETICS & HEREDITY | Genetic Association Studies | Face - abnormalities | Humans | Micrognathism - genetics | Hypotrichosis - genetics | Chromatin Assembly and Disassembly - genetics | Foot Deformities, Congenital - genetics | Male | Neck - abnormalities | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Syndrome | Chromosomal Proteins, Non-Histone - genetics | Intellectual Disability - genetics | SMARCB1 Protein | Hand Deformities, Congenital - genetics | Facies | Female | Mutation | Nuclear Proteins - genetics | DNA Helicases - genetics | Abnormalities, Multiple - genetics | Body height
SMARCE1 | SMARCB1 | intellectual disability (ID) | SWI/SNF complex | Coffin–Siris syndrome | ARID1A | SMARCA2 | ARID1B | Nicolaides–Baraitser syndrome | SMARCA4 | Intellectual disability (ID) | Coffin-Siris syndrome | Nicolaides-Baraitser syndrome | DELINEATION | CHROMATIN-REMODELING COMPLEX | GENETICS & HEREDITY | Genetic Association Studies | Face - abnormalities | Humans | Micrognathism - genetics | Hypotrichosis - genetics | Chromatin Assembly and Disassembly - genetics | Foot Deformities, Congenital - genetics | Male | Neck - abnormalities | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Syndrome | Chromosomal Proteins, Non-Histone - genetics | Intellectual Disability - genetics | SMARCB1 Protein | Hand Deformities, Congenital - genetics | Facies | Female | Mutation | Nuclear Proteins - genetics | DNA Helicases - genetics | Abnormalities, Multiple - genetics | Body height
Journal Article
Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, 1/2018, Volume 144, Issue 1, pp. 109 - 115
The pituitary production of human chorionic gonadotropin (hCG) can cause false-positive results during or after germ cell tumor (GCT) treatment. Because...
Medicine & Public Health | Hematology | False positive | Pituitary hCG | Oncology | Cancer Research | Internal Medicine | Testicular germ cell tumor | hCG | ONCOLOGY | MEN | NONPREGNANT WOMEN | BETA | Luteinizing Hormone - blood | Pituitary Gland - metabolism | Humans | Middle Aged | False Positive Reactions | Neoplasms, Germ Cell and Embryonal - blood | Young Adult | Testosterone - administration & dosage | Reagent Kits, Diagnostic | Chorionic Gonadotropin - blood | Immunoassay - methods | Adult | Aged | Retrospective Studies | Testicular Neoplasms - blood | Testosterone | Glycoproteins | Chorionic gonadotropin | Tumors
Medicine & Public Health | Hematology | False positive | Pituitary hCG | Oncology | Cancer Research | Internal Medicine | Testicular germ cell tumor | hCG | ONCOLOGY | MEN | NONPREGNANT WOMEN | BETA | Luteinizing Hormone - blood | Pituitary Gland - metabolism | Humans | Middle Aged | False Positive Reactions | Neoplasms, Germ Cell and Embryonal - blood | Young Adult | Testosterone - administration & dosage | Reagent Kits, Diagnostic | Chorionic Gonadotropin - blood | Immunoassay - methods | Adult | Aged | Retrospective Studies | Testicular Neoplasms - blood | Testosterone | Glycoproteins | Chorionic gonadotropin | Tumors
Journal Article
Scientific Reports, ISSN 2045-2322, 09/2016, Volume 6, p. 33861
We identified drug seeds for treating Huntington's disease (HD) by combining in vitro single molecule fluorescence spectroscopy, in silico molecular docking...
NEURAL STEM-CELLS | REPAIR | RNA | TRANSPORTERS | INTERACTS | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | EXPANSION | BINDING PROTEIN | REPEATS | AGGREGATION | Fluorescence spectroscopy | Huntingtons disease | Spectroscopy | Animal models | Angiotensin III | Oligopeptides | Light scattering | DNA damage | Body weight | Motor task performance | Huntington's disease | DNA repair | Molecular modelling | Histidine | Life span | Angiotensin
NEURAL STEM-CELLS | REPAIR | RNA | TRANSPORTERS | INTERACTS | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | EXPANSION | BINDING PROTEIN | REPEATS | AGGREGATION | Fluorescence spectroscopy | Huntingtons disease | Spectroscopy | Animal models | Angiotensin III | Oligopeptides | Light scattering | DNA damage | Body weight | Motor task performance | Huntington's disease | DNA repair | Molecular modelling | Histidine | Life span | Angiotensin
Journal Article
Plant Production Science, ISSN 1343-943X, 01/2007, Volume 10, Issue 3, pp. 322 - 328
Stomatal conductance (g s ) is an important trait responsible for the genotypic difference in gas diffusion for photosynthesis and transpiration in rice (Oryza...
Rice (Oryza sativa L.) | Specific stomatal conductance | Stomatal density | Rice diverse research set of germplasm (RDRS) | Stomatal conductance | Stomatal length | stomatal conductance | FREQUENCIES | JAPONICA | AGRONOMY | YIELD | VARIETIES | WHEAT | TRANSPIRATION | rice (Oryza sativa L.) | specific stomata] conductance | INDICA | TEMPERATURE | stomatal density | stomatal length | rice diverse research set of germplasm (RDRS) | LEAF GAS-EXCHANGE | PHOTOSYNTHESIS
Rice (Oryza sativa L.) | Specific stomatal conductance | Stomatal density | Rice diverse research set of germplasm (RDRS) | Stomatal conductance | Stomatal length | stomatal conductance | FREQUENCIES | JAPONICA | AGRONOMY | YIELD | VARIETIES | WHEAT | TRANSPIRATION | rice (Oryza sativa L.) | specific stomata] conductance | INDICA | TEMPERATURE | stomatal density | stomatal length | rice diverse research set of germplasm (RDRS) | LEAF GAS-EXCHANGE | PHOTOSYNTHESIS
Journal Article
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, ISSN 0031-6903, 08/2017, Volume 137, Issue 8, pp. 999 - 1003
Several case studies have reported a possible drug interaction between warfarin and tramadol where tramadol coadministration enhanced the antithrombotic...
tramadol | PHARMACOLOGY & PHARMACY | prothrombin time-international normalized ratio | risk factor | drug interaction | warfarin | Glomerular Filtration Rate | Cardiovascular Diseases - drug therapy | Humans | Middle Aged | Prothrombin Time | Risk Factors | Tramadol - pharmacology | Logistic Models | Male | Warfarin - administration & dosage | Warfarin - pharmacology | Drug Synergism | International Normalized Ratio | Fibrinolytic Agents - pharmacology | Drug Interactions | Tramadol - administration & dosage | Aged, 80 and over | Female | Aged | Fibrinolytic Agents - administration & dosage | Drug Therapy, Combination | Serum Albumin - metabolism
tramadol | PHARMACOLOGY & PHARMACY | prothrombin time-international normalized ratio | risk factor | drug interaction | warfarin | Glomerular Filtration Rate | Cardiovascular Diseases - drug therapy | Humans | Middle Aged | Prothrombin Time | Risk Factors | Tramadol - pharmacology | Logistic Models | Male | Warfarin - administration & dosage | Warfarin - pharmacology | Drug Synergism | International Normalized Ratio | Fibrinolytic Agents - pharmacology | Drug Interactions | Tramadol - administration & dosage | Aged, 80 and over | Female | Aged | Fibrinolytic Agents - administration & dosage | Drug Therapy, Combination | Serum Albumin - metabolism
Journal Article
Yakugaku Zasshi, ISSN 0031-6903, 2017, Volume 137, Issue 8, pp. 999 - 1003
Journal Article
Acute Medicine & Surgery, ISSN 2052-8817, 01/2017, Volume 4, Issue 1, pp. 57 - 67
Aim In Japan, trauma surgery training remains insufficient, and on‐the‐job training has become increasingly difficult because of the decreasing number of...
self‐assessment of confidence levels (SACL) | half‐year follow‐up | educational seminar for trauma surgery | cadaver | skills retention | Seminars | Ostomy | Skills | Surgery | Questionnaires | Emergency medical care | Anesthesiology | Neurosurgery | Endoscopy | Retention | Trauma
self‐assessment of confidence levels (SACL) | half‐year follow‐up | educational seminar for trauma surgery | cadaver | skills retention | Seminars | Ostomy | Skills | Surgery | Questionnaires | Emergency medical care | Anesthesiology | Neurosurgery | Endoscopy | Retention | Trauma
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 2013, Volume 36, Issue 2, pp. 215 - 221
Photodynamic therapy (PDT) induces selective cell death of neoplastic tissue and connecting vasculature by combining photosensitizers with light. Here we...
Journal Article
Acute Medicine & Surgery, ISSN 2052-8817, 04/2019, Volume 6, Issue 2, pp. 123 - 130
Aim Senior surgeons in Japan who participated in “cadaver‐based educational seminar for trauma surgery (CESTS)” subsequently stated their interest in seminars...
Advanced seminar | saturated salt solution | surgical skills training | cadaver‐based educational seminar for trauma surgery | self‐assessment of confidence levels | Seminars | Ostomy | Pulmonary arteries | Skills | Surgery | Liver | Questionnaires | Trauma | Veins & arteries | Abdomen
Advanced seminar | saturated salt solution | surgical skills training | cadaver‐based educational seminar for trauma surgery | self‐assessment of confidence levels | Seminars | Ostomy | Pulmonary arteries | Skills | Surgery | Liver | Questionnaires | Trauma | Veins & arteries | Abdomen
Journal Article
Photosynthesis Research, ISSN 0166-8595, 10/2007, Volume 94, Issue 1, pp. 23 - 30
In order to evaluate genotypic variation, we measured leaf photosynthetic rate (Pn) and its associated factors for the rice diversity research set of germplasm...
Life Sciences | Carbon isotope discrimination | Indica | C i /C a : gas conductance | Genotype groups | Oryza sativa L | Nitrogen concentration | Plant Physiology | Japonica | gas conductance | indica | QTL ANALYSIS | CARBON-ISOTOPE DISCRIMINATION | genotype groups | LEAVES | carbon isotope discrimination | japonica | VARIETIES | USE EFFICIENCY | conductance | PLANT SCIENCES | ORYZA-SATIVA L | nitrogen concentration | STOMATAL CONDUCTANCE | NITROGEN-CONTENT | C-i/C-a : gas | Oryza - genetics | Plant Leaves - genetics | Plant Leaves - metabolism | Oryza - metabolism | Genotype | Photosynthesis | Oryza - cytology | Genotype & phenotype
Life Sciences | Carbon isotope discrimination | Indica | C i /C a : gas conductance | Genotype groups | Oryza sativa L | Nitrogen concentration | Plant Physiology | Japonica | gas conductance | indica | QTL ANALYSIS | CARBON-ISOTOPE DISCRIMINATION | genotype groups | LEAVES | carbon isotope discrimination | japonica | VARIETIES | USE EFFICIENCY | conductance | PLANT SCIENCES | ORYZA-SATIVA L | nitrogen concentration | STOMATAL CONDUCTANCE | NITROGEN-CONTENT | C-i/C-a : gas | Oryza - genetics | Plant Leaves - genetics | Plant Leaves - metabolism | Oryza - metabolism | Genotype | Photosynthesis | Oryza - cytology | Genotype & phenotype
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2016, Volume 6, Issue 1
Journal Article
16.
Full Text
Saturated salt solution method: A useful cadaver embalming for surgical skills training
Medicine (United States), ISSN 0025-7974, 12/2014, Volume 93, Issue 27, p. e196
This article evaluates the suitability of cadavers embalmed by the saturated salt solution (SSS) method for surgical skills training (SST). SST courses using...
PRESERVATION | ANATOMY | RESIDENTS | MEDICINE, GENERAL & INTERNAL | PLACEMENT | FORMALIN | CATHETERS | FRESH-FROZEN CADAVER | VASCULAR-SURGERY | THIEL | PARAVERTEBRAL PUNCTURE | Embalming - methods | Sodium Chloride | Quality Improvement | Humans | Range of Motion, Articular | Aged, 80 and over | Disinfection | Female | Male | Organ Preservation Solutions | General Surgery - education | Cadaver
PRESERVATION | ANATOMY | RESIDENTS | MEDICINE, GENERAL & INTERNAL | PLACEMENT | FORMALIN | CATHETERS | FRESH-FROZEN CADAVER | VASCULAR-SURGERY | THIEL | PARAVERTEBRAL PUNCTURE | Embalming - methods | Sodium Chloride | Quality Improvement | Humans | Range of Motion, Articular | Aged, 80 and over | Disinfection | Female | Male | Organ Preservation Solutions | General Surgery - education | Cadaver
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 02/2013, Volume 36, Issue 2, p. 215
Photodynamic therapy (PDT) induces selective cell death of neoplastic tissue and connecting vasculature by combining photosensitizers with light. Here we...
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2008, Volume 283, Issue 35, pp. 23533 - 23541
Halobacterium salinarum sensory rhodopsin I ( HsSRI), a dual receptor regulating both negative and positive phototaxis in haloarchaea, transmits light signals...
MUTATION ANALYSIS | CHARGED RESIDUES | HALOBACTERIUM-HALOBIUM | RETINAL PROTEIN | STRUCTURAL-CHANGES | COGNATE TRANSDUCER | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSIENT MOVEMENT | PHARAONIS PHOBORHODOPSIN | TRANSDUCER PROTEIN | NATRONOBACTERIUM-PHARAONIS | Archaeal Proteins - metabolism | Recombinant Proteins - metabolism | Gene Expression | Bacterial Proteins - genetics | Recombinant Proteins - genetics | Genome, Bacterial - physiology | Sensory Rhodopsins - genetics | Archaea - metabolism | Bacteroidetes - metabolism | Escherichia coli - genetics | Halobacterium salinarum - genetics | Archaeal Proteins - genetics | Bacterial Proteins - metabolism | Halobacterium salinarum - metabolism | Signal Transduction - physiology | Archaea - genetics | Bacteroidetes - genetics | Sensory Rhodopsins - metabolism | Membrane Transport, Structure, Function, and Biogenesis
MUTATION ANALYSIS | CHARGED RESIDUES | HALOBACTERIUM-HALOBIUM | RETINAL PROTEIN | STRUCTURAL-CHANGES | COGNATE TRANSDUCER | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSIENT MOVEMENT | PHARAONIS PHOBORHODOPSIN | TRANSDUCER PROTEIN | NATRONOBACTERIUM-PHARAONIS | Archaeal Proteins - metabolism | Recombinant Proteins - metabolism | Gene Expression | Bacterial Proteins - genetics | Recombinant Proteins - genetics | Genome, Bacterial - physiology | Sensory Rhodopsins - genetics | Archaea - metabolism | Bacteroidetes - metabolism | Escherichia coli - genetics | Halobacterium salinarum - genetics | Archaeal Proteins - genetics | Bacterial Proteins - metabolism | Halobacterium salinarum - metabolism | Signal Transduction - physiology | Archaea - genetics | Bacteroidetes - genetics | Sensory Rhodopsins - metabolism | Membrane Transport, Structure, Function, and Biogenesis
Journal Article
Virology, ISSN 0042-6822, 2010, Volume 410, Issue 1, pp. 38 - 47
Abstract To identify the host factors implicated in the regulation of hepatitis C virus (HCV) genome replication, we performed comparative proteome analyses of...
Infectious Disease | Chaperonin | Replication | Hepatitis C virus | Non-structural protein | HSP90 | COMPLEX | DEPENDENT RNA-POLYMERASE | SUBGENOMIC REPLICON | UBIQUITIN LIGASE | REVERSE-TRANSCRIPTASE | SHOCK COGNATE PROTEIN | VIROLOGY | IN-VIVO | HCV REPLICATION | EXPRESSION | Gene Expression Regulation, Viral - physiology | Humans | Hepacivirus - genetics | Viral Nonstructural Proteins - genetics | Chaperonins - metabolism | RNA, Viral - genetics | Viral Core Proteins - genetics | Viral Core Proteins - metabolism | Cell Line, Tumor | Hepatocytes - virology | Hepacivirus - physiology | Viral Nonstructural Proteins - metabolism | RNA, Viral - metabolism | Virus Replication - physiology | Proteins | Synthesis | RNA | Hepatitis C | Genomics
Infectious Disease | Chaperonin | Replication | Hepatitis C virus | Non-structural protein | HSP90 | COMPLEX | DEPENDENT RNA-POLYMERASE | SUBGENOMIC REPLICON | UBIQUITIN LIGASE | REVERSE-TRANSCRIPTASE | SHOCK COGNATE PROTEIN | VIROLOGY | IN-VIVO | HCV REPLICATION | EXPRESSION | Gene Expression Regulation, Viral - physiology | Humans | Hepacivirus - genetics | Viral Nonstructural Proteins - genetics | Chaperonins - metabolism | RNA, Viral - genetics | Viral Core Proteins - genetics | Viral Core Proteins - metabolism | Cell Line, Tumor | Hepatocytes - virology | Hepacivirus - physiology | Viral Nonstructural Proteins - metabolism | RNA, Viral - metabolism | Virus Replication - physiology | Proteins | Synthesis | RNA | Hepatitis C | Genomics
Journal Article
Sarcoidosis Vasculitis and Diffuse Lung Diseases, ISSN 1124-0490, 2017, Volume 34, Issue 1, pp. 85 - 90