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PLoS ONE, ISSN 1932-6203, 09/2009, Volume 4, Issue 9, p. e6963
Background: Inflammation followed by fibrosis is a component of islet dysfunction in both rodent and human type 2 diabetes. Because islet inflammation may... 
NADPH OXIDASE | GOTO-KAKIZAKI RAT | PANCREATIC-ISLETS | RENIN-ANGIOTENSIN SYSTEM | INTERLEUKIN-1 RECEPTOR ANTAGONIST | NITRIC-OXIDE SYNTHASE | BIOLOGY | CARDIOVASCULAR-DISEASE | NECROSIS-FACTOR-ALPHA | BETA-CELL MASS | HEME OXYGENASE-1 | Interleukin-1 - metabolism | Oxidative Stress | Rats, Wistar | Antioxidants - metabolism | Gene Expression Regulation | Rats | Male | Inflammation | Diabetes Mellitus, Type 2 - metabolism | Animals | Endothelial Cells - cytology | Models, Biological | Interleukin 1 Receptor Antagonist Protein - metabolism | Islets of Langerhans - cytology | Diabetes Mellitus, Experimental - metabolism | Type 2 diabetes | Interleukins | RNA | Genes | Angiotensin | Genetic research | Gene expression | Vascular endothelial growth factor | Endothelium | Oxidative stress | Laboratories | Interleukin | Biology | Activation | Interleukin 1 receptors | Kinases | Epoxide hydrolase | Cell adhesion & migration | Vascularization | Proteins | Angiogenesis | Signal transduction | Cell activation | Hyperglycemia | Rodents | Atherosclerosis | Interleukin 1 | Angiotensinogen | Trends | Pancreas | Immune system | Cardiovascular system | Hypertension | Cytokines | Interleukin 1 receptor antagonist | Diabetes mellitus | Metabolism | Apolipoproteins | Fibrinolysis | Cholesterol | Endothelial cells | Polymerase chain reaction | Pathology | Arachidonate 12-lipoxygenase | Arteriosclerosis | Fibrosis | Insulin resistance | Islets of Langerhans | Diabetes | Lipoxygenase | Endocrinology
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e90045
Regenerating (REG) proteins are associated with islet development, beta-cell damage, diabetes and pancreatitis. Particularly, REG-1 and REG-3-beta are involved... 
ISLET INFLAMMATION | STONE PROTEIN/REGENERATING PROTEIN | OXIDATIVE STRESS | REG3-BETA GENES | MULTIDISCIPLINARY SCIENCES | BETA-CELL | REG GENE | KNOCKOUT MICE | UP-REGULATION | SPONTANEOUS MODEL | FAMILY | Antigens, Neoplasm - genetics | Chemokines - blood | Chemokines - secretion | Rats, Wistar | Diabetes Mellitus, Type 2 - genetics | Gene Expression Regulation | Lithostathine - genetics | Rats | Male | Diabetes Mellitus, Type 2 - metabolism | Lectins, C-Type - genetics | Pancreatitis-Associated Proteins | Lectins, C-Type - metabolism | Lithostathine - metabolism | Diabetes Mellitus, Type 2 - blood | Macrophages - metabolism | Animals | Islets of Langerhans - metabolism | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Biomarkers, Tumor - genetics | Diabetes Mellitus, Type 2 - pathology | Proteins | Immunohistochemistry | Type 2 diabetes | Interleukins | RNA | MHC antibodies | Genes | Pancreatitis | Inflammation | Gene expression | Cell culture | Interleukin | Antibodies | Homeostasis | Paraffin | Macrophages | Experiments | Interleukin 6 | Angiogenesis | Hyperglycemia | Cell growth | Rodents | Tumor necrosis factor-TNF | Pancreas | Localization | Vascular endothelial growth factor | Acinar cells | Medical research | Cell survival | Cytokines | Secretion | Diabetes mellitus | Insulin | Medicine | Polymerase chain reaction | Major histocompatibility complex | Ligands | Infiltration | Islets of Langerhans | Diabetes | Histocompatibility | Chemokines | Life Sciences | Human health and pathology
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 06/2006, Volume 55, Issue 6, pp. 1625 - 1633
Journal Article
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 2011, Volume 1812, Issue 6, pp. 699 - 702
Diabetes mellitus is associated with increased risk for cardiovascular disorders, which are major causes of mortality in this disease. Hyperhomocysteinemia,... 
Type 2 diabetes | Cystathionine beta synthase | Goto–Kakizaki rat | Homocysteine | Prediabetes | Glutathione | Goto-Kakizaki rat | OXIDATIVE STRESS | HYPERHOMOCYSTEINEMIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MELLITUS | GK RAT | BIOPHYSICS | METABOLISM | DIET | INSULIN-RESISTANCE | LIVER | BETA-CELL | SERUM HOMOCYSTEINE | Life Sciences | Biochemistry, Molecular Biology
Journal Article
ILAR journal / National Research Council, Institute of Laboratory Animal Resources, ISSN 1084-2020, 2004, Volume 45, Issue 3, pp. 237 - 258
Type 1 diabetes (T1D) is a T cell-mediated autoimmune disease in which insulin-producing beta cells of the pancreatic islets of Langerhans are destroyed. The... 
Autoantigens - analysis | Animals | Diabetes Mellitus, Type 1 - etiology | Autoimmunity - immunology | Humans | Diabetes Mellitus, Type 1 - pathology | Neurosecretory Systems - immunology | Autoimmunity - genetics | Female | Male | Mice, Inbred NOD | Mice
Journal Article
Review of Diabetic Studies, ISSN 1613-6071, 03/2010, Volume 7, Issue 1, pp. 36 - 44
Journal Article
Experimental Neurology, ISSN 0014-4886, 2010, Volume 222, Issue 1, pp. 125 - 134
Journal Article
Brain Research, ISSN 0006-8993, 2002, Volume 957, Issue 2, pp. 345 - 353
Journal Article