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Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7654, pp. 305 - 310
Cerebral cavernous malformations (CCMs) are a cause of stroke and seizure for which no effective medical therapies yet exist. CCMs arise from the loss of an... 
BACTERIA | ANGIOGENESIS | MEKK3 | DISEASE | RECEPTOR | COMMUNITIES | PROTEINS | ENDOGENOUS LIGANDS | EXPRESSION | LPS | INTERFACE | STABILITY | MULTIDISCIPLINARY SCIENCES | GENES | LIPOPOLYSACCHARIDE | HOST | INSIGHTS | Injections, Intravenous | Humans | Lipopolysaccharides - administration & dosage | Male | Hemangioma, Cavernous, Central Nervous System - immunology | Gram-Negative Bacteria - immunology | Lipopolysaccharides - immunology | Lipopolysaccharide Receptors - metabolism | Toll-Like Receptor 4 - deficiency | Female | Toll-Like Receptor 4 - antagonists & inhibitors | Disease Susceptibility | Hemangioma, Cavernous, Central Nervous System - microbiology | Signal Transduction | Endothelial Cells - metabolism | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - immunology | Immunity, Innate | Animals | Hemangioma, Cavernous, Central Nervous System - pathology | Germ-Free Life | Lipopolysaccharide Receptors - genetics | Anti-Bacterial Agents - pharmacology | Mice | Gastrointestinal Microbiome - immunology | Anti-Bacterial Agents - administration & dosage | Toll-like receptors | Physiological aspects | Health aspects | Hemangioma, Cavernous | Brain | Stroke | Gnotobiotics | Pathogenesis | Pharmacology | TLR4 protein | Gene expression | CD14 antigen | Endothelial cells | Proteins | Signal transduction | Signaling | Stimulants | Antibiotics | Bacteria | Gram-negative bacteria | Lung Kruppel-like factor | Brain diseases | Immune system | Index Medicus
Journal Article
Chemistry of Materials, ISSN 0897-4756, 03/2012, Volume 24, Issue 6, pp. 1198 - 1204
Journal Article
Cell Reports, ISSN 2211-1247, 02/2018, Volume 22, Issue 6, pp. 1545 - 1559
Yin yang 1 (YY1) is a ubiquitous transcription factor and mammalian polycomb group protein (PcG) with important functions to regulate embryonic development,... 
YY1 | hematopoietic stem cell | quiescence | c-Kit | cell cycle | polycomb group protein | PROGENITOR CELLS | RECRUITMENT | MAINTENANCE | CYCLE REGULATION | YIN-YANG-1 | REPRESSION | IN-VIVO | COMPLEXES | SELF-RENEWAL | DIFFERENTIATION | CELL BIOLOGY
Journal Article
Science Translational Medicine, ISSN 1946-6234, 11/2019, Volume 11, Issue 520, p. eaaw3521
Cerebral cavernous malformation (CCM) is a genetic, cerebrovascular disease. Familial CCM is caused by genetic mutations in KRIT1, CCM2, or PDCD10. Disease... 
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2014, Volume 193, Issue 2, pp. 797 - 806
Journal Article
Cancer Research, ISSN 0008-5472, 12/2000, Volume 60, Issue 24, pp. 7084 - 7093
Journal Article
by Melander, A and Olsson, J and Lindberg, G and Salzman, A and Howard, T and Stang, P and Lydick, E and Emslie-Smith, A and Boyle, D I. R and Evans, J M. M and Macdonald, T M and Bain, J and Sullivan, F and Juhl, C and Pørksen, N and Sturis, J and Hollingdal, M and Pincus, S and Veldhuis, J and Dejgaard, A and Schmitz, O and Kristensen, J S and Frandsen, K B and Bayer, Th and Müller, P and Dunning, B E and Paladini, S and Gutierrez, C and Deacon, R and Valentin, M and Grunberger, G and Weston, W M and Patwardhan, R and Rappaport, E B and Sargeant, L A and Wareham, N J and Khaw, K T and Zethelius, Björn and Lithell, Hans and Hales, C Nicholas and Berne, Christian and Lakka, H.-M and Oksanen, L and Tuomainen, T.-P and Kontula, K and Salonen, J T and Dekker, J M and de Boks, P and de Vegt, F and Stehouwer, C D. A and Nijpels, G and Bouter, L M and Heine, R J and Bruno, G and Cavallo-Perin, P and Bargero, G and D’Errico, N and Borra, M and Macchia, G and Pagano, G and Newton, R W and Ruta, D A and New, J P and Wallace, C and Roxburgh, M A and Young, R J and Vaughan, N J. A and Elliott, P and Brennan, G and Devers, M and MacAlpine, R and Steinke, D and Lawson, D H and Decallonne, B and Casteels, K and Gysemans, C and Bouillon, R and Mathieu, C and Linn, Thomas and Strate, Christine and Schneider, Kerstin and Funda, D P and Jirsa Jr, M and Kozáková, H and Kaas, A and Kofronová, O and Tlaskalová-Hogenová, H and Buschard, K and Wanka, H and Hartmann, A and Kuttler, B and Rasmussen, S B and Sørensen, T S and Markholst, H and Petersen, J S and Karounos, D and Dyrberg, T and Mabley, J G and Haskó, G and Szabó, C and ... and IMDIAB Study Group and Osaka IDDM Study Group and European Group for the Study of Insulin Resistance (EGIR) and Screen-Pol Study Group and Northern Diabetic Pregnancy Survey and Brazilian Gestational Diabetes Study Group and UK Prospective Diabetes Study Group and Hungarian HbA1c Screening Study Group and Croatian Study Group for Diabetic Amyotrophy and EURODIAB IDDM Study Group and Neuropathy Study Group of the Italian Society of the Study of Diabetes and Pittsburgh Epidemiology of Diabetes Complications (EDC) Study and HOE 901/3003 study group and German Working Group on Quality Control and Turkish Diabetes Epidemiology Group and Mauritian NCD group and D.I.O.R. study group and Lithuanian Collaborative Group for the Epidemiology of Diabetes and DARTS/MEMO Collaboration and Cerivastatin/Bezafibrate Latin America Study Group and Pramlintide Type 1 Study Group and Non-Invasive Task Force and Childhood Diabetes in Finland Study Group and German Pediat. Working Group and EURODIAB Complications Study Group and Hvidøre Study group on Childhood Diabetes and EURODIAB Prospective Complications Study (PCS) Group and WHO/IDF Patient Empowerment Workshop and AD Morris for the DARTS/MEMO Collaboration and Pramlintide Type 2 Study Group and Finnish Diabetes Prevention Study Group and Service of internal medecine - diabetologia - vascular diseases and UKPDS Group and IGT Research Group and DAIS Project Group and KANWU study group and Cerivastatin Combination Therapy Study Group and GENEDIAB Study Group and TARDIS Steering Committee and UK centres and Rosiglitazone Study Group and GEDEC study group and HIDM investigators and US Study Group of Insulin Glargine in Type 2 DM and European Insulin Aspart Study Group and The TARDIS Steering Committee and UK centres and The Turkish Diabetes Epidemiology Group and The EURODIAB Prospective Complications Study (PCS) Group and The Pittsburgh Epidemiology of Diabetes Complications (EDC) Study and The Finnish Diabetes Prevention Study Group
Diabetologia, ISSN 0012-186X, 8/1999, Volume 42, Issue S1, pp. A1 - A330
Journal Article
by Gerstein, Hertzel C and Colhoun, Helen M and Dagenais, Gilles and Dagenais, Gilles R and Diaz, Rafael and Diaz, Sarahy and Lakshmanan, Mark and Pais, Prem and Probstfield, Jeffrey and Riesmeyer, Jeffrey S and Riddle, Matthew C and Rydén, Lars and Xavier, Denis and Atisso, Charles Messan and Dyal, Leanne and Hall, Stephanie and Hall, Charles and Rao-Melacini, Purnima and Wong, Gloria and Avezum, Alvaro and Basile, Jan and Chung, Ming-Min and Chung, Namsik and Chung, Jin-Wook and Conget, Ignacio and Cushman, William C and Franek, Edward and Hancu, Nicolae and Hanefeld, Christoph and Hanefeld, Markolf and Holt, Shaun and Jansky, Petr and Keltai, Matyas and Keltai, Katalin and Lanas, Fernando and Leiter, Lawrence A and Lopez-Jaramillo, Patricio and Cardona Munoz, Ernesto German and Pirags, Valdis and Pogosova, Nana and Raubenheimer, Peter J and Shaw, Jonathan E and Sheu, Wayne H-H and Temelkova-Kurktschiev, Theodora and Abella, Mercedes and Alebuena, Andrea and Almagro, Sandra and Amoroso, Eduardo and Anadon, Paula and Andreu, Elizabeth and Aristimuño, Guillermo and Arzadun, Maria and Barbieri, Maria and Barcudi, Raul and Bartolacci, Ines and Bolobanich, Gabriel and Bordonava, Anselmo and Bustamante Labarta, Miguel and Bustos, Betina and Caccavo, Alberto and Camino, Alejandra and Cantero, Maria and Carignano, Maria and Cartasegna, Luis and Cipullo, Marcela and Commendatore, Víctor and Conosciuto, Victoria and Costamagna, Osvaldo and Crespo, Claudia and Cuello, Jose and Cuneo, Carlos and Cusimano, Sandra and Dean, Sofia and Dituro, Claudio and Dominguez, Andrea and Farah, Miguel and Fernandez, Alberto and Fernandez, Florencia and Ferrari, Adriana and Flammia, Patricia and Fuentealba, Jose and Gallardo, Karina Beatriz and Garcia, Mar and Garcia, Celso and Garcia, Maria and Garcia Duran, Ruben and Garrido, Marcelo and Gavicola, Rodolfo and Gerbaudo, Claudio and Gilli, Graciela and Giotto, Ana Paula and Godoy Bolzán, Pedro and Gomez Vilamajo, Oscar and Guerlloy, Fernando and Guridi, Cristian and Gutierrez Garrido, Narcisa and Hasbani, Eduardo and Hermida, Sonia and Hominal, Miguel and Hrabar, Adrian and ... and REWIND Investigators
The Lancet, ISSN 0140-6736, 07/2019, Volume 394, Issue 10193, pp. 121 - 130
Journal Article
by Kato, Norihiro and Loh, Marie and Takeuchi, Fumihiko and Verweij, Niek and Wang, Xu and Zhang, Weihua and NKelly, Tanika and Saleheen, D and Lehne, Benjamin and Leach, Irene Mateo and ng, Alexander and Abbott, James and Wahl, Simone and Tan, Sian-Tsung and Scott, William R and Campanella, Gianluca and Chadeau-Hyam, Marc and Afzal, Uzma and Ahluwalia, Tarunveer Singh and Bonder, Marc and Chen, Ping and Dehghan, Abbas and Edwards, Todd L and Esko, Tõnu and Go, Min Jin and Harris, Sarah and Hartiala, Jaana and Kasela, Silva and Kasturiratne, Anuradhani and Khor, C.C and Kleber, Marcus and Li, Huaixing and Mok, Zuan Yu and Nakatochi, Masahiro and Sapari, Nur Sabrina and Saxena, Richa and Stewart, Alexane F and Stolk, Lisette and Tabara, Yasuharu and Teh, Ai Ling and Wu, Ying and Wu, Jer-Yuarn and Zhang, Yi and Aits, Imke and Da Silva Couto Alves, Alexessander and Das, Shikta and Dorajoo, Rajkumar and CHopewell, Jemma and Kim, Yun Kyoung and WKoivula, Robert and Luan, Jian'An and Lyytikäinen, Leo-Pekka and NNguyen, Quang and Pereira, Mark A and Postmus, Douwe and TRaitakari, Olli and Scannell Bryan, Molly and Scott, Robert and Sorice, R and Tragante, Vinicius and Traglia, Michela and White, Jon and Yamamoto, Ken and Zhang, Yonghong and Adair, Linda and Ahmed, Alauddin and Akiyama, Koichi and Asif, Rasheed and Aung, Tin and Barroso, Inês and Bjonnes, Anew and Braun, Timothy R and Cai, Hui and Chang, Li-Ching and Chen, C.-H and Cheng, Ching-Yu and Chong, Yap-Seng and Collins, Francis and Courtney, Regina and Davies, Gail and Delgado, G and Do, Loi D and Doevendans, Pieter and Gansevoort, Ron and Gao, Ying and Grammer, Tanja B and Grarup, Niels and Grewal, Jagvir and Gu, D and SWander, Gurpreet and Hartikainen, A.L and Hazen, Stanley and He, Jing and Heng, Chew-Kiat and Hixso, E. James Ames and Hofman, Albert and Hsu, Chris and Huang, Wei and Husemoen, Lise Lotte and Hwang, Joo-Yeon and ... and InterAct Consortium and BIOS-consortium and LifeLines Cohort Study and CARDIo GRAMplusCD and The InterAct Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Umeå universitet
Nature Genetics, ISSN 1061-4036, 11/2015, Volume 47, Issue 11, pp. 1282 - 1293
Journal Article