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1. Full Text Bronchoskopische Thermoablation bei Patienten mit schwerem heterogenem Lungenemphysem: 12-Monats-Daten
by Gompelmann, D and Eberhardt, R and Snell, G and Hopkins, P and Baker, K and Witt, C and Valipour, A and Wagner, M and Stanzel, F and Egan, J and Ernst, A and Kesten, S and Herth, FJF
Pneumologie, ISSN 0934-8387, 02/2012
Conference Proceeding
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2. Full Text Salt Sensitivity of Blood Pressure Is Associated With Polymorphisms in the Sodium-Bicarbonate Cotransporter
by Carey, Robert M and Schoeffel, Cynthia D and Gildea, John J and Jones, John E and McGrath, Helen E and Gordon, Lindsay N and Park, Min Jeong and Sobota, Rafal S and Underwood, Patricia C and Williams, Jonathan and Sun, Bei and Raby, Benjamin and Lasky-Su, Jessica and Hopkins, Paul N and Adler, Gail K and Williams, Scott M and Jose, Pedro A and Felder, Robin A
Hypertension (Dallas, Tex. 1979), ISSN 0194-911X, 11/2012, Volume 60, Issue 5, pp. 1359 - 1366
blood pressure | genetics | hypertension | salt sensitivity | sodium-bicarbonate cotransporter | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Biological and medical sciences | Arterial hypertension. Arterial hypotension | Medical sciences | Clinical manifestations. Epidemiology. Investigative techniques. Etiology | Blood and lymphatic vessels | Meta-Analysis as Topic | Outcome Assessment (Health Care) | Blood Pressure - genetics | Humans | Middle Aged | Sodium-Bicarbonate Symporters - genetics | Sodium Chloride, Dietary - administration & dosage | Male | Hypertension - etiology | Dose-Response Relationship, Drug | Adult | Female | Blood Pressure - physiology | Hypertension - genetics | Odds Ratio | Body Mass Index | Genetic Predisposition to Disease - genetics | Gene Frequency | Sodium Chloride, Dietary - adverse effects | Aldosterone - blood | Genotype | Logistic Models | Renin - blood | Hypertension - physiopathology | Diet | Polymorphism, Single Nucleotide | Index Medicus
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3. Full Text Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10
by Maeder, Morgan L and Stefanidakis, Michael and Wilson, Christopher J and Baral, Reshica and Barrera, Luis Alberto and Bounoutas, George S and Bumcrot, David and Chao, Hoson and Ciulla, Dawn M and DaSilva, Jennifer A and Dass, Abhishek and Dhanapal, Vidya and Fennell, Tim J and Friedland, Ari E and Giannoukos, Georgia and Gloskowski, Sebastian W and Glucksmann, Alexandra and Gotta, Gregory M and Jayaram, Hariharan and Haskett, Scott J and Hopkins, Bei and Horng, Joy E and Joshi, Shivangi and Marco, Eugenio and Mepani, Rina and Reyon, Deepak and Ta, Terence and Tabbaa, Diana G and Samuelsson, Steven J and Shen, Shen and Skor, Maxwell N and Stetkiewicz, Pam and Wang, Tongyao and Yudkoff, Clifford and Myer, Vic E and Albright, Charles F and Jiang, Haiyan
Nature medicine, ISSN 1078-8956, 02/2019, Volume 25, Issue 2, pp. 229 - 233
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Retinal degeneration | Care and treatment | Genetic aspects | Research | Gene mutations | Staphylococcus aureus | Explants | CRISPR | Blindness | Retina | Genomes | Dystrophy | Nuclease | Mutation | Gene expression | Genetic modification | Index Medicus
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4. Full Text The Fok1 vitamin D receptor gene polymorphism is associated with plasma renin activity in Caucasians
by Vaidya, Anand and Sun, Bei and Forman, John P and Hopkins, Paul N and Brown, Nancy J and Kolatkar, Nikheel S and Williams, Gordon H and Williams, Jonathan S
Clinical endocrinology (Oxford), ISSN 0300-0664, 06/2011, Volume 74, Issue 6, pp. 783 - 790
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Endocrinopathies | Medical sciences | Vertebrates: endocrinology | European Continental Ancestry Group - genetics | Cross-Sectional Studies | Gene Frequency | Humans | Middle Aged | Sodium Chloride, Dietary - adverse effects | Sodium Chloride, Dietary - administration & dosage | Genotype | Linear Models | Male | Renin - blood | Receptors, Calcitriol - genetics | Hypertension - etiology | Linkage Disequilibrium | Vitamin D - blood | Hypertension - blood | Adult | Female | Vitamin D - analogs & derivatives | Blood Pressure - drug effects | Polymorphism, Single Nucleotide | Hypertension - genetics | Hypertension | Medical colleges | Vitamin D | Analysis | Genetic research | Calcifediol | Genetic aspects | Alfacalcidol | Diabetes | Index Medicus | polymorphism | VDR | vitamin D | renin | Fok1
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5. Full Text Replication and meta-analysis of the gene-environment interaction between body mass index and the interleukin-6 promoter polymorphism with higher insulin resistance
by Underwood, Patricia C and Chamarthi, Bindu and Williams, Jonathan S and Sun, Bei and Vaidya, Anand and Raby, Benjamin A and Lasky-Su, Jessica and Hopkins, Paul N and Adler, Gail K and Williams, Gordon H
Metabolism, clinical and experimental, ISSN 0026-0495, 2012, Volume 61, Issue 5, pp. 667 - 671
Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Feeding. Feeding behavior | Biological and medical sciences | Vertebrates: anatomy and physiology, studies on body, several organs or systems | Body Mass Index | Interleukin-6 - genetics | Humans | Middle Aged | Homeostasis | Male | Insulin - blood | Obesity - genetics | Promoter Regions, Genetic - genetics | Polymorphism, Genetic | Phenotype | Insulin Resistance - physiology | Insulin Resistance - genetics | Environment | Female | Polymorphism, Single Nucleotide | Blood Glucose - metabolism | Hypertension | Type 2 diabetes | Body mass index | Interleukins | Analysis | Genes | Insulin resistance | Genetic aspects | Glucose | Diabetes | Dextrose | Index Medicus | Evaluation | Obesity | Fasting | Meta analysis | Diabetes mellitus | Environmental factors | Hormones | Gene polymorphism | Insulin | Blood | Homozygotes | Interleukin 6 | Reviews | Body mass | Sodium | Genetics | Replication | Models | Interleukin-6 gene | Insulin Resistance
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6. Full Text The association of the angiotensinogen gene with insulin sensitivity in humans: a tagging single nucleotide polymorphism and haplotype approach
by Underwood, Patricia C and Sun, Bei and Williams, Jonathan S and Pojoga, Luminita H and Raby, Benjamin and Lasky-Su, Jessica and Hunt, Steven and Hopkins, Paul N and Jeunemaitre, Xavier and Adler, Gail K and Williams, Gordon H
Metabolism, clinical and experimental, ISSN 0026-0495, 2011, Volume 60, Issue 8, pp. 1150 - 1157
Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Feeding. Feeding behavior | Biological and medical sciences | Vertebrates: anatomy and physiology, studies on body, several organs or systems | Haplotypes | Genetic Association Studies | Gene Frequency | Humans | Middle Aged | Genotype | Male | Hypertension - metabolism | Angiotensinogen - genetics | Insulin - metabolism | Alleles | Insulin Resistance - genetics | Adult | Female | Polymorphism, Single Nucleotide | Hypertension - genetics | Mutation | Insulin - genetics | Hypertension | Analysis | Angiotensin | Genetic research | Insulin resistance | Genetic aspects | Insulin | Sex | Homeostasis | Single-nucleotide polymorphism | Regression analysis | Population genetics | angiotensinogen | Body mass index | Genotyping | AGT gene | Models | Age | Siblings | Index Medicus
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7. Full Text Lysine-Specific Demethylase 1: An Epigenetic Regulator of Salt-Sensitive Hypertension
by Williams, Jonathan S and Chamarthi, Bindu and Goodarzi, Mark O and Pojoga, Luminita H and Sun, Bei and Garza, Amanda E and Raby, Benjamin A and Adler, Gail K and Hopkins, Paul N and Brown, Nancy J and Jeunemaitre, Xavier and Ferri, Claudio and Fang, Rui and Leonor, Thiago and Cui, Jinrui and Guo, Xiuqing and Taylor, Kent D and Chen, Yii-Der Ida and Xiang, Anny and Raffel, Leslie J and Buchanan, Thomas A and Rotter, Jerome I and Williams, Gordon H and Shi, Yujiang
American journal of hypertension, ISSN 0895-7061, 7/2012, Volume 25, Issue 7, pp. 812 - 817
salt-sensitivity | blood pressure | genetics | LSD-1 | epigenetic | hypertension | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Biological and medical sciences | Arterial hypertension. Arterial hypotension | Medical sciences | Clinical manifestations. Epidemiology. Investigative techniques. Etiology | Blood and lymphatic vessels | Oxidoreductases, N-Demethylating - genetics | Epigenesis, Genetic | Humans | Kidney - enzymology | Sodium Chloride, Dietary - administration & dosage | African Americans - genetics | Histone Demethylases - genetics | Hypertension - etiology | Phenotype | Animals | Blood Pressure - physiology | Mice | Hypertension - genetics | Hypertension | Sodium in the body | Covalent modifications | Development and progression | Genetic aspects | Health aspects | Index Medicus | Genetics | Epigenetic | Salt-sensitivity | LSD1
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8. Full Text Variants in Striatin Gene Are Associated With Salt-Sensitive Blood Pressure in Mice and Humans
by Garza, Amanda E and Rariy, Chevon M and Sun, Bei and Williams, Jonathan S and Lasky-Su, Jessica and Baudrand, Rene and Yao, Tham and Moize, Burhanuddin and Hafiz, Wan M and Romero, Jose R and Adler, Gail K and Ferri, Claudio and Hopkins, Paul N and Pojoga, Luminita H and Williams, Gordon H
Hypertension (Dallas, Tex. 1979), ISSN 0194-911X, 01/2015, Volume 65, Issue 1, pp. 211 - 217
Blood Pressure | Striatin Protein | Mouse | Single Nucleotide | Polymorphism | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Calmodulin-Binding Proteins - genetics | Sodium, Dietary - adverse effects | Blood Pressure - genetics | Membrane Proteins - genetics | Humans | RNA, Messenger - genetics | Gene Expression Regulation | Genotype | Signal Transduction - genetics | Nerve Tissue Proteins - genetics | Blotting, Western | Hypertension - physiopathology | Hypertension - metabolism | Mice, Knockout | Membrane Proteins - biosynthesis | Phenotype | Animals | Calmodulin-Binding Proteins - biosynthesis | Nerve Tissue Proteins - biosynthesis | Polymerase Chain Reaction | Mice | Hypertension - genetics | Disease Models, Animal | Index Medicus | salt-sensitivity | blood pressure | Striatin | mineralocorticoid receptor | SNP | aldosterone
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9. Full Text Variants of the Caveolin-1 Gene: A Translational Investigation Linking Insulin Resistance and Hypertension
by Pojoga, Luminita H and Underwood, Patricia C and Goodarzi, Mark O and Williams, Jonathan S and Adler, Gail K and Jeunemaitre, Xavier and Hopkins, Paul N and Raby, Benjamin A and Lasky-Su, Jessica and Sun, Bei and Cui, Jinrui and Guo, Xiuqing and Taylor, Kent D and Chen, Yii-Der Ida and Xiang, Anny and Raffel, Leslie J and Buchanan, Thomas A and Rotter, Jerome I and Williams, Gordon H
The journal of clinical endocrinology and metabolism, ISSN 0021-972X, 08/2011, Volume 96, Issue 8, pp. E1288 - E1292
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | European Continental Ancestry Group - genetics | Hispanic Americans - genetics | Humans | Translational Medical Research | Caveolin 1 - genetics | Male | Signal Transduction - genetics | Genetic Markers | Insulin - blood | Hypertension - physiopathology | Hypertension - metabolism | Mice, Knockout | Caveolin 1 - metabolism | Genetic Variation | Phenotype | Animals | Insulin Resistance - genetics | Mice | Polymorphism, Single Nucleotide | Fasting - metabolism | Hypertension - genetics | Hypertension | Translation | Fasting | Calcium channels (voltage-gated) | biomarkers | Single-nucleotide polymorphism | Gene polymorphism | Insulin | Glucose tolerance | Homozygotes | Body mass index | caveolin-1 | Reviews | Blood pressure | Age | Siblings | Index Medicus | Abridged Index Medicus | 100 | Brief Reports | 4 | 500 | 16 | JCEM Online
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10. Full Text Polymorphisms in the serum- and glucocorticoid-inducible kinase 1 gene are associated with blood pressure and renin response to dietary salt intake
by Rao, A.D and Sun, B and Saxena, A and Hopkins, P.N and Jeunemaitre, X and Brown, N.J and Adler, G.K and Williams, J.S
Journal of human hypertension, ISSN 0950-9240, 03/2013, Volume 27, Issue 3, pp. 176 - 180
Renin | Salt sensitivity | SGK1 | Polymorphism | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | United States - epidemiology | Blood Pressure - genetics | Humans | Middle Aged | Sodium Chloride, Dietary - administration & dosage | Male | Hypertension - blood | Renin-Angiotensin System | Adult | Female | Hypertension - enzymology | Hypertension - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Gene Frequency | Sodium Chloride, Dietary - adverse effects | Protein-Serine-Threonine Kinases - genetics | Europe - epidemiology | Linear Models | Logistic Models | Biomarkers - blood | Chi-Square Distribution | Renin - blood | Hypertension - physiopathology | Linkage Disequilibrium | Phenotype | Immediate-Early Proteins - genetics | Hypertension - ethnology | Polymorphism, Single Nucleotide | Animal experimentation | Hypertension | Salt | Usage | Care and treatment | Physiological aspects | Blood pressure | Genetic aspects | Research | Health aspects | Phosphotransferases | Genetic polymorphisms | Index Medicus | polymorphism | renin | salt sensitivity
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11. Full Text Lysine-specific demethylase-1 modifies the age effect on blood pressure sensitivity to dietary salt intake
by Krug, Alexander W and Krug, Alexander W and Tille, Eric and Tille, Eric and Sun, Bei and Sun, Bei and Pojoga, Luminita and Pojoga, Luminita and Williams, Jonathan and Williams, Jonathan and Chamarthi, Bindu and Chamarthi, Bindu and Lichtman, Andrew H and Lichtman, Andrew H and Hopkins, Paul N and Hopkins, Paul N and Adler, Gail K and Adler, Gail K and Williams, Gordon H and Williams, Gordon H
AGE, ISSN 0161-9152, 10/2013, Volume 35, Issue 5, pp. 1809 - 1820
Life Sciences | Geriatrics/Gerontology | Dietary salt | Age-associated blood pressure regulation | LSD1 | Molecular Medicine | Epigenetic regulation | Cell Biology | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Sodium, Dietary - adverse effects | Humans | Middle Aged | Aging - drug effects | Male | Hypertension - physiopathology | Hypertension - etiology | Hypertension - metabolism | Dose-Response Relationship, Drug | Young Adult | Histone Demethylases - metabolism | Animals | Aging - physiology | Adult | Female | Sodium, Dietary - administration & dosage | Aged | Blood Pressure - drug effects | Mice | Oxidoreductases, N-Demethylating - metabolism | Disease Models, Animal | Physiological aspects | Epigenetic inheritance | Blood pressure | Genetic aspects | Research | Lysine | Studies | Medical research | Salt | Gerontology | Statistical analysis | Diet | Aging | Polymorphism | Index Medicus
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