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JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 04/2019, Volume 81, p. 36
In 1889, Stephen Paget first proposed that organ distribution of metastases is a non-random event, yet metastatic organotropism remains one of the greatest... 
Brain | Profiling | Epithelial cells | Brain tumors | Liver | Lung cancer | Kupffer cells | Metastasis | Exosomes | Metastases | Blood plasma | Homing | Proteins | Fibroblasts | Bioindicators | Signatures | Computational fluid dynamics | Tumor cells | Invasiveness | Breast cancer | Patients | Endothelial cells | Body fluids | Hepatocytes | Biopsy | Pancreatic cancer | Proteomics | Cell lines | Biomarkers | Organotropism | Cell migration | Niches | Cancer | Tumors | Integrins
Journal Article
Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7660, pp. 609 - 610
The growth factor MIDKINE, which is secreted by skin tumours called melanomas, stimulates the formation of lymphatic vessels at distant lymph nodes and organ... 
Lymphatic system | Vessels | Melanoma | Metastasis | Paving | Lymph nodes | Metastases | Proteins | Researchers | Medical prognosis | Skin | Growth factors | Midkine | Cancer | Tumors | Lymph
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 06/2015, Volume 17, Issue 6, pp. 816 - 826
Journal Article
by Hoshino, Ayuko and Costa-Silva, Bruno and Shen, Tang-Long and Rodrigues, Goncalo and Hashimoto, Ayako and Tesic Mark, Milica and Molina, Henrik and Kohsaka, Shinji and Di Giannatale, Angela and Ceder, Sophia and Singh, Swarnima and Williams, Caitlin and Soplop, Nadine and Uryu, Kunihiro and Pharmer, Lindsay and King, Tari and Bojmar, Linda and Davies, Alexander E and Ararso, Yonathan and Zhang, Tuo and Zhang, Haiying and Hernandez, Jonathan and Weiss, Joshua M and Dumont-Cole, Vanessa D and Kramer, Kimberly and Wexler, Leonard H and Narendran, Aru and Schwartz, Gary K and Healey, John H and Sandstrom, Per and Jørgen Labori, Knut and Kure, Elin H and Grandgenett, Paul M and Hollingsworth, Michael A and De Sousa, Maria and Kaur, Sukhwinder and Jain, Maneesh and Mallya, Kavita and Batra, Surinder K and Jarnagin, William R and Brady, Mary S and Fodstad, Oystein and Muller, Volkmar and Pantel, Klaus and Minn, Andy J and Bissell, Mina J and Garcia, Benjamin A and Kang, Yibin and Rajasekhar, Vinagolu K and Ghajar, Cyrus M and Matei, Irina and Peinado, Hector and Bromberg, Jacqueline and Lyden, David and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States) and Weill Cornell Medicine, New York, NY (United States) and Memorial Sloan Kettering Cancer Center, New York, NY (United States) and Medicinska fakulteten and Region Östergötland and Kirurgiska kliniken US and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Avdelningen för kliniska vetenskaper and Centrum för kirurgi, ortopedi och cancervård
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7578, pp. 329 - 335
Ever since Stephen Paget's 1889 hypothesis, metastatic organotropism has remained one of cancer's greatest mysteries. Here we demonstrate that exosomes from... 
CELLS | BONE METASTASES | VESICLES | BREAST-CANCER METASTASIS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GROWTH | NICHE | MICROVESICLES | PROTEINS | PROTEOMICS | Exosomes - metabolism | Tropism | Phosphorylation | Epithelial Cells - metabolism | Receptors, Vitronectin - antagonists & inhibitors | Humans | Lung - cytology | Integrin beta4 - metabolism | Integrins - metabolism | Brain - metabolism | Integrin alpha6beta1 - metabolism | S100 Proteins - genetics | Neoplasm Metastasis - prevention & control | Female | Kupffer Cells - metabolism | Lung - metabolism | Receptors, Vitronectin - metabolism | Epithelial Cells - cytology | Integrin alpha6beta4 - metabolism | Fibroblasts - metabolism | Biomarkers - metabolism | Brain - cytology | Kupffer Cells - cytology | Endothelial Cells - metabolism | Liver - metabolism | Mice, Inbred C57BL | Integrin alpha6beta4 - antagonists & inhibitors | Organ Specificity | Animals | Endothelial Cells - cytology | Neoplasm Metastasis - pathology | Cell Line, Tumor | Integrin beta Chains - metabolism | Fibroblasts - cytology | Liver - cytology | Mice | Genes, src | Integrins - antagonists & inhibitors | Complications and side effects | Development and progression | Cell organelles | Metastasis | Health aspects | Integrins | Tumors | Studies | Microscopy | Liver | Melanoma | Fibroblasts | Breast cancer | Chemokines | Index Medicus | mechanisms of disease | cancer microenvironment | BASIC BIOLOGICAL SCIENCES | metastasis | 60 APPLIED LIFE SCIENCES | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Nature Medicine, ISSN 1078-8956, 06/2012, Volume 18, Issue 6, pp. 883 - 891
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2018, Volume 20, Issue 3, pp. 332 - 343
Journal Article
Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7660, pp. 609 - 610
Journal Article
PloS one, ISSN 1932-6203, 2019, Volume 14, Issue 3, pp. e0214826 - e0214826
[This corrects the article DOI: 10.1371/journal.pone.0199012.]. 
Endocytosis | Cyclodextrin | Breast cancer | Cyclodextrins | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2018, Volume 13, Issue 7, pp. e0199012 - e0199012
Most breast cancer deaths are caused by metastasis and treatment options beyond radiation and cytotoxic drugs, which have severe side effects, and hormonal... 
METHYL-BETA-CYCLODEXTRIN | CELLS | PROTEIN | METASTASIS | CHOLESTEROL | MULTIDISCIPLINARY SCIENCES | LIPID RAFTS | ALPHA-V-BETA-3 INTEGRIN | EXOSOMES | RISK | GENOME-WIDE ASSOCIATION | Genome-Wide Association Study | Phosphoric Monoester Hydrolases - genetics | alpha-Cyclodextrins - metabolism | Humans | Triple Negative Breast Neoplasms - drug therapy | alpha-Cyclodextrins - administration & dosage | Acyltransferases - genetics | Breast Neoplasms - drug therapy | Breast Neoplasms - metabolism | Breast Neoplasms - genetics | Phospholipid Transfer Proteins - genetics | Triple Negative Breast Neoplasms - genetics | Breast Neoplasms - pathology | Triple Negative Breast Neoplasms - metabolism | 2-Hydroxypropyl-beta-cyclodextrin - therapeutic use | Triple Negative Breast Neoplasms - pathology | Polymorphism, Single Nucleotide - genetics | Female | Adenosine Triphosphatases - genetics | Endocytosis - genetics | ATP Binding Cassette Transporter 1 - genetics | Care and treatment | Usage | Endocytosis | Oncology, Experimental | Development and progression | Breast cancer | Genetic aspects | Cyclodextrins | Research | Health aspects | Cancer | Pediatrics | Leukocyte migration | Mesenchyme | Estrogens | Epilepsy | Genes | Radiation | Medical services | Clinical trials | Cytotoxicity | AKT protein | Lipids | Genomes | Phospholipids | Single-nucleotide polymorphism | Statistical methods | Metastasis | Exosomes | Exocytosis | Cancer therapies | DNA repair | Metastases | ABCA1 protein | Phosphatidylinositol | Genetics | Medical research | Phenotypes | Statistical analysis | Developmental biology | Tumor cells | Gene expression | Cholesterol | Studies | Autism | Side effects | Cyclodextrin | Computer applications | Packaging | Breast | ATP-binding protein | Product development | Cell migration | Ototoxicity | Integrins | Index Medicus
Journal Article