Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 5, pp. 680 - 691
To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC), we pooled data from multiple genome-wide genotyping...
BREAST-CANCER | COMMON VARIANTS | METAANALYSIS | CLEAR-CELL | ALGORITHM | GENETICS & HEREDITY | RISK | ASSOCIATION | CARCINOMA | ENDOMETRIOSIS | TELOMERE LENGTH | Neoplasms, Glandular and Epithelial - pathology | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Meta-Analysis as Topic | Humans | Risk Factors | Genetic Loci - genetics | Ovarian Neoplasms - pathology | Genotype | Ovarian Neoplasms - genetics | BRCA1 Protein - genetics | Neoplasms, Glandular and Epithelial - genetics | Telomere-Binding Proteins - genetics | Alleles | Carcinoma, Ovarian Epithelial | Female | Polymorphism, Single Nucleotide | Mutation | BRCA2 Protein - genetics | Genetic susceptibility | Physiological aspects | Genetic aspects | Single nucleotide polymorphisms | Identification and classification | Health aspects | Risk factors | Ovarian cancer | Carriers | Medical research | Ovarian carcinoma | Genes | Gene regulation | Genomes | Breast cancer | Loci | Cancer | Life Sciences | Human health and pathology | Genetics | Medical and Health Sciences | Medicin och hälsovetenskap
BREAST-CANCER | COMMON VARIANTS | METAANALYSIS | CLEAR-CELL | ALGORITHM | GENETICS & HEREDITY | RISK | ASSOCIATION | CARCINOMA | ENDOMETRIOSIS | TELOMERE LENGTH | Neoplasms, Glandular and Epithelial - pathology | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Meta-Analysis as Topic | Humans | Risk Factors | Genetic Loci - genetics | Ovarian Neoplasms - pathology | Genotype | Ovarian Neoplasms - genetics | BRCA1 Protein - genetics | Neoplasms, Glandular and Epithelial - genetics | Telomere-Binding Proteins - genetics | Alleles | Carcinoma, Ovarian Epithelial | Female | Polymorphism, Single Nucleotide | Mutation | BRCA2 Protein - genetics | Genetic susceptibility | Physiological aspects | Genetic aspects | Single nucleotide polymorphisms | Identification and classification | Health aspects | Risk factors | Ovarian cancer | Carriers | Medical research | Ovarian carcinoma | Genes | Gene regulation | Genomes | Breast cancer | Loci | Cancer | Life Sciences | Human health and pathology | Genetics | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 04/2015, Volume 100, Issue 4, pp. L36 - L36
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 06/2015, Volume 100, Issue 6, pp. L47 - L48
Journal Article
2000, ISBN 1853177555, x, 253
Book
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2011, Volume 128, Issue 2, pp. 360 - 365.e4
Background Partially hydrolyzed whey formula (pHWF) has been recommended for infants with a family history of allergic disease at the cessation of exclusive...
Allergy and Immunology | infant formulas | Allergy prevention | eczema | asthma | allergic rhinitis | randomized control trial | conventional cow's milk formulas | partially hydrolyzed whey formula | FOOD ALLERGY | TOLERANCE | PREVENTION | IMMUNOLOGY | BETA-LACTOGLOBULIN | ATOPIC-DERMATITIS | MILK FORMULA | ALLERGY | NUTRITIONAL INTERVENTION | MANIFESTATIONS | LIFE | Single-Blind Method | Hypersensitivity - prevention & control | Milk Proteins - analysis | Skin Tests | Weaning | Humans | Infant Food | Child, Preschool | Infant | Infant Formula - chemistry | Risk | Hydrolysis | Milk Proteins - administration & dosage | Animals | Cattle | Hypersensitivity - diagnosis | Whey Proteins | Child | Infant Formula - administration & dosage | Infant, Newborn | Allergy | Baby foods industry | Infants | Children | Breast feeding | Allergic reaction | Risk factors | Diseases | Infection control | Studies | Babies | Food allergies | Allergies | Eczema | Milk
Allergy and Immunology | infant formulas | Allergy prevention | eczema | asthma | allergic rhinitis | randomized control trial | conventional cow's milk formulas | partially hydrolyzed whey formula | FOOD ALLERGY | TOLERANCE | PREVENTION | IMMUNOLOGY | BETA-LACTOGLOBULIN | ATOPIC-DERMATITIS | MILK FORMULA | ALLERGY | NUTRITIONAL INTERVENTION | MANIFESTATIONS | LIFE | Single-Blind Method | Hypersensitivity - prevention & control | Milk Proteins - analysis | Skin Tests | Weaning | Humans | Infant Food | Child, Preschool | Infant | Infant Formula - chemistry | Risk | Hydrolysis | Milk Proteins - administration & dosage | Animals | Cattle | Hypersensitivity - diagnosis | Whey Proteins | Child | Infant Formula - administration & dosage | Infant, Newborn | Allergy | Baby foods industry | Infants | Children | Breast feeding | Allergic reaction | Risk factors | Diseases | Infection control | Studies | Babies | Food allergies | Allergies | Eczema | Milk
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2011, Volume 128, Issue 4, pp. 782 - 788.e9
Background Identification of children at risk of developing asthma provides a window of opportunity for risk-reducing interventions. Allergen sensitization...
Allergy and Immunology | eczema | Birth cohort | asthma | sensitization | house dust mite | wheeze | ALLERGEN EXPOSURE | EARLY-CHILDHOOD | RISK | IMMUNOLOGY | CHILDREN | PATHOGENESIS | ALLERGY | DISEASE | AEROALLERGENS | BIRTH-COHORT | ATOPIC SENSITIZATION | Allergens - adverse effects | Predictive Value of Tests | Skin Tests | Age Factors | Follow-Up Studies | Eczema - immunology | Humans | Hypersensitivity | Child, Preschool | Infant | Male | Australia - epidemiology | Eczema - etiology | Animals | Eczema - epidemiology | Allergens - immunology | Female | Pyroglyphidae | Respiratory Sounds | Child | Infant, Newborn | Allergens | Allergy | Children | Asthma in children | Health aspects | Allergic reaction | Food allergies | Allergies | Age | Food
Allergy and Immunology | eczema | Birth cohort | asthma | sensitization | house dust mite | wheeze | ALLERGEN EXPOSURE | EARLY-CHILDHOOD | RISK | IMMUNOLOGY | CHILDREN | PATHOGENESIS | ALLERGY | DISEASE | AEROALLERGENS | BIRTH-COHORT | ATOPIC SENSITIZATION | Allergens - adverse effects | Predictive Value of Tests | Skin Tests | Age Factors | Follow-Up Studies | Eczema - immunology | Humans | Hypersensitivity | Child, Preschool | Infant | Male | Australia - epidemiology | Eczema - etiology | Animals | Eczema - epidemiology | Allergens - immunology | Female | Pyroglyphidae | Respiratory Sounds | Child | Infant, Newborn | Allergens | Allergy | Children | Asthma in children | Health aspects | Allergic reaction | Food allergies | Allergies | Age | Food
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 12/2006, Volume 21, pp. P22 - P22
Biochemical measurements of bone turnover provide an objective assessment of disease activity and the response to treatment. Alkaline phosphatase is the best...
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 03/2011, Volume 103, Issue 5, pp. 425 - 435
Background Genome-wide association studies have identified several common genetic variants associated with breast cancer risk. It is likely, however, that a...
COMMON VARIANTS | WOMEN | IDENTIFIES 2 | ONCOLOGY | MENARCHE | COLORECTAL-CANCER | CONFER SUSCEPTIBILITY | RISK | RS6983267 | POLYMORPHISM | AGE | Humans | Middle Aged | DNA Repair Enzymes - genetics | Gene Expression Regulation, Neoplastic | Case-Control Studies | Actins - genetics | Adult | Female | Surveys and Questionnaires | Odds Ratio | Breast Neoplasms - ethnology | Quality Control | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Risk Factors | Genotype | Logistic Models | United Kingdom | Chromosomes, Human, Pair 9 | Chromosomes, Human, Pair 6 | DNA-Binding Proteins - genetics | Linkage Disequilibrium | Breast Neoplasms - genetics | Aged | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 10 | Kruppel-Like Transcription Factors - genetics | Development and progression | Disease susceptibility | Breast cancer | Genetic aspects | Research | Risk factors | Etiology | Introns | Estrogens | Genetic diversity | Mapping | Deserts | Cancer
COMMON VARIANTS | WOMEN | IDENTIFIES 2 | ONCOLOGY | MENARCHE | COLORECTAL-CANCER | CONFER SUSCEPTIBILITY | RISK | RS6983267 | POLYMORPHISM | AGE | Humans | Middle Aged | DNA Repair Enzymes - genetics | Gene Expression Regulation, Neoplastic | Case-Control Studies | Actins - genetics | Adult | Female | Surveys and Questionnaires | Odds Ratio | Breast Neoplasms - ethnology | Quality Control | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Risk Factors | Genotype | Logistic Models | United Kingdom | Chromosomes, Human, Pair 9 | Chromosomes, Human, Pair 6 | DNA-Binding Proteins - genetics | Linkage Disequilibrium | Breast Neoplasms - genetics | Aged | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 10 | Kruppel-Like Transcription Factors - genetics | Development and progression | Disease susceptibility | Breast cancer | Genetic aspects | Research | Risk factors | Etiology | Introns | Estrogens | Genetic diversity | Mapping | Deserts | Cancer
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 02/2011, Volume 26, Issue 2, pp. 242 - 251
The selective cathepsin K inhibitor odanacatib (ODN) progressively increased bone mineral density (BMD) and decreased bone‐resorption markers during 2 years of...
CLINICAL TRIAL | BONE MINERAL DENSITY | ODANACATIB | CATHEPSIN K | POSTMENOPAUSAL WOMEN | OSTEOPOROSIS | PHASE 2B | TARGET | RESORPTION | TURNOVER | OSTEOCLASTS | ALENDRONATE | IN-VIVO | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | BALICATIB | CATHEPSIN-K INHIBITOR | Bone Resorption | Bone Density | Bone and Bones - physiology | Collagen Type I - metabolism | Double-Blind Method | Humans | Middle Aged | Hip - pathology | Biphenyl Compounds - therapeutic use | Osteoporosis, Postmenopausal - drug therapy | Peptides - metabolism | Time Factors | Placebos | Female | Aged | Lumbar Vertebrae - pathology
CLINICAL TRIAL | BONE MINERAL DENSITY | ODANACATIB | CATHEPSIN K | POSTMENOPAUSAL WOMEN | OSTEOPOROSIS | PHASE 2B | TARGET | RESORPTION | TURNOVER | OSTEOCLASTS | ALENDRONATE | IN-VIVO | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | BALICATIB | CATHEPSIN-K INHIBITOR | Bone Resorption | Bone Density | Bone and Bones - physiology | Collagen Type I - metabolism | Double-Blind Method | Humans | Middle Aged | Hip - pathology | Biphenyl Compounds - therapeutic use | Osteoporosis, Postmenopausal - drug therapy | Peptides - metabolism | Time Factors | Placebos | Female | Aged | Lumbar Vertebrae - pathology
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 09/2011, Volume 26, Issue 9, pp. 2261 - 2270
Two trials have shown that a single 5‐mg infusion of zoledronic acid achieves much higher response rates in Paget disease of bone than risedronate. The...
BISPHOSPHONATES | PAGET DISEASE | RISEDRONATE | QUALITY OF LIFE | BONE TURNOVER MARKERS | CONTROLLED-TRIAL | RESPONSES | ENDOCRINOLOGY & METABOLISM | BONE TURNOVER | Bone and Bones - pathology | Recurrence | Osteitis Deformans - diagnostic imaging | Humans | Alkaline Phosphatase - metabolism | Imidazoles - administration & dosage | Bone Remodeling - drug effects | Bone and Bones - drug effects | Bone and Bones - diagnostic imaging | Diphosphonates - therapeutic use | Imidazoles - therapeutic use | Diphosphonates - adverse effects | Biomarkers - metabolism | Osteitis Deformans - drug therapy | Bone Density Conservation Agents - adverse effects | Imidazoles - adverse effects | Kaplan-Meier Estimate | Bone Density Conservation Agents - therapeutic use | Treatment Outcome | Diphosphonates - administration & dosage | Imidazoles - pharmacology | Bone Density Conservation Agents - administration & dosage | Remission Induction | Bone Density Conservation Agents - pharmacology | Randomized Controlled Trials as Topic | Bone and Bones - physiopathology | Osteitis Deformans - physiopathology | Radionuclide Imaging | Quality of Life | Aged | Infusions, Intravenous | Diphosphonates - pharmacology
BISPHOSPHONATES | PAGET DISEASE | RISEDRONATE | QUALITY OF LIFE | BONE TURNOVER MARKERS | CONTROLLED-TRIAL | RESPONSES | ENDOCRINOLOGY & METABOLISM | BONE TURNOVER | Bone and Bones - pathology | Recurrence | Osteitis Deformans - diagnostic imaging | Humans | Alkaline Phosphatase - metabolism | Imidazoles - administration & dosage | Bone Remodeling - drug effects | Bone and Bones - drug effects | Bone and Bones - diagnostic imaging | Diphosphonates - therapeutic use | Imidazoles - therapeutic use | Diphosphonates - adverse effects | Biomarkers - metabolism | Osteitis Deformans - drug therapy | Bone Density Conservation Agents - adverse effects | Imidazoles - adverse effects | Kaplan-Meier Estimate | Bone Density Conservation Agents - therapeutic use | Treatment Outcome | Diphosphonates - administration & dosage | Imidazoles - pharmacology | Bone Density Conservation Agents - administration & dosage | Remission Induction | Bone Density Conservation Agents - pharmacology | Randomized Controlled Trials as Topic | Bone and Bones - physiopathology | Osteitis Deformans - physiopathology | Radionuclide Imaging | Quality of Life | Aged | Infusions, Intravenous | Diphosphonates - pharmacology
Journal Article
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, ISSN 1073-449X, 06/2014, Volume 189, Issue 11, pp. 1351 - 1358
Rationale: Better characterization of childhood wheeze phenotypes using newer statistical methods provides a basis for addressing the heterogeneity of...
RISK-FACTORS | ADULTHOOD | LUNG-FUNCTION | respiratory function | SPIROMETRY | asthma | CHILDREN | PEDIATRIC ASTHMA | birth cohort | RESPIRATORY SYSTEM | 1ST 6 YEARS | LIFE | CRITICAL CARE MEDICINE | Asthma - diagnosis | Spirometry | Prognosis | Prospective Studies | Asthma - physiopathology | Follow-Up Studies | Humans | Risk Factors | Male | Respiratory Sounds - etiology | Respiratory Sounds - physiopathology | Asthma - genetics | Australia - epidemiology | Disease Progression | Forced Expiratory Volume | Phenotype | Time Factors | Asthma - complications | Adolescent | Hypersensitivity - diagnosis | Female | Surveys and Questionnaires | Child | Asthma - epidemiology
RISK-FACTORS | ADULTHOOD | LUNG-FUNCTION | respiratory function | SPIROMETRY | asthma | CHILDREN | PEDIATRIC ASTHMA | birth cohort | RESPIRATORY SYSTEM | 1ST 6 YEARS | LIFE | CRITICAL CARE MEDICINE | Asthma - diagnosis | Spirometry | Prognosis | Prospective Studies | Asthma - physiopathology | Follow-Up Studies | Humans | Risk Factors | Male | Respiratory Sounds - etiology | Respiratory Sounds - physiopathology | Asthma - genetics | Australia - epidemiology | Disease Progression | Forced Expiratory Volume | Phenotype | Time Factors | Asthma - complications | Adolescent | Hypersensitivity - diagnosis | Female | Surveys and Questionnaires | Child | Asthma - epidemiology
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 12/2014, Volume 99, Issue 12, pp. 4408 - 4422
Objective: The aim of this guideline was to formulate practice guidelines for the diagnosis and treatment of Paget's disease of the bone. Participants: The...
ZOLEDRONIC ACID | OSTEITIS DEFORMANS | HEARING-LOSS | BIOCHEMICAL MARKERS | GIANT-CELL TUMOR | ALKALINE-PHOSPHATASE | BISPHOSPHONATE THERAPY | ENDOCRINOLOGY & METABOLISM | DIPHOSPHONATE TREATMENT | TURNOVER MARKERS | ASSESSING RESPONSE | Osteitis Deformans - complications | Reproducibility of Results | Humans | Biomarkers - analysis | Osteitis Deformans - diagnosis | Evidence-Based Medicine | Consensus | Osteitis Deformans - therapy
ZOLEDRONIC ACID | OSTEITIS DEFORMANS | HEARING-LOSS | BIOCHEMICAL MARKERS | GIANT-CELL TUMOR | ALKALINE-PHOSPHATASE | BISPHOSPHONATE THERAPY | ENDOCRINOLOGY & METABOLISM | DIPHOSPHONATE TREATMENT | TURNOVER MARKERS | ASSESSING RESPONSE | Osteitis Deformans - complications | Reproducibility of Results | Humans | Biomarkers - analysis | Osteitis Deformans - diagnosis | Evidence-Based Medicine | Consensus | Osteitis Deformans - therapy
Journal Article
Journal of Pediatrics, The, ISSN 0022-3476, 2014, Volume 164, Issue 2, pp. 289 - 294.e2
Objective To define longitudinal childhood wheeze phenotypes and identify their early-life risk factors. Study design Current wheeze was recorded 23 times up...
Pediatrics | Body mass index | Melbourne Atopy Cohort Study | MACS | LRTI | LCA | Latent class analysis | BMI | Lower respiratory tract infection | Relative risk | INFECTIONS | SENSITIZATION | ECZEMA | DISEASE | LUNG-FUNCTION | ASTHMA | PEDIATRICS | ASSOCIATION | CHILDREN | HISTORY | Body Mass Index | Respiratory Sounds - genetics | Allergens - adverse effects | Prognosis | Humans | Risk Factors | Child, Preschool | Infant | Male | Hypersensitivity - complications | Respiratory Sounds - etiology | Respiratory Tract Infections - genetics | Disease Progression | Phenotype | Tobacco Smoke Pollution - adverse effects | Time Factors | Female | Hypersensitivity - genetics | Respiratory Tract Infections - complications | Child | Wheeze | Genetic aspects | Medicine, Preventive | Risk factors | Preventive health services
Pediatrics | Body mass index | Melbourne Atopy Cohort Study | MACS | LRTI | LCA | Latent class analysis | BMI | Lower respiratory tract infection | Relative risk | INFECTIONS | SENSITIZATION | ECZEMA | DISEASE | LUNG-FUNCTION | ASTHMA | PEDIATRICS | ASSOCIATION | CHILDREN | HISTORY | Body Mass Index | Respiratory Sounds - genetics | Allergens - adverse effects | Prognosis | Humans | Risk Factors | Child, Preschool | Infant | Male | Hypersensitivity - complications | Respiratory Sounds - etiology | Respiratory Tract Infections - genetics | Disease Progression | Phenotype | Tobacco Smoke Pollution - adverse effects | Time Factors | Female | Hypersensitivity - genetics | Respiratory Tract Infections - complications | Child | Wheeze | Genetic aspects | Medicine, Preventive | Risk factors | Preventive health services
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2008, Volume 121, Issue 5, pp. 1190 - 1195
Background The atopic march hypothesis suggests that infants with eczema are at increased risk of asthma. Others argue that eczema is not a risk factor for...
Allergy and Immunology | Atopic march | eczema | allergy prevention | asthma | DERMATITIS | RISK | PREVALENCE | IMMUNOLOGY | ALLERGY | SENSITIZATION | atopic march | YOUNG-CHILDREN | ONSET | LIFE | Skin Tests | Humans | Risk Factors | Child, Preschool | Infant | Male | Dermatitis, Atopic - complications | Asthma - complications | Age of Onset | Sex Factors | Female | Infant, Newborn | Asthma - epidemiology | Studies | Food allergies | Hypotheses | Statistical analysis | Eczema | Families & family life | Allergies | Age | Girls | Asthma
Allergy and Immunology | Atopic march | eczema | allergy prevention | asthma | DERMATITIS | RISK | PREVALENCE | IMMUNOLOGY | ALLERGY | SENSITIZATION | atopic march | YOUNG-CHILDREN | ONSET | LIFE | Skin Tests | Humans | Risk Factors | Child, Preschool | Infant | Male | Dermatitis, Atopic - complications | Asthma - complications | Age of Onset | Sex Factors | Female | Infant, Newborn | Asthma - epidemiology | Studies | Food allergies | Hypotheses | Statistical analysis | Eczema | Families & family life | Allergies | Age | Girls | Asthma
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Full Text
Childhood wheeze phenotypes show less than expected growth in FEV 1 across adolescence
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 06/2014, Volume 189, Issue 11, pp. 1351 - 1358
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2008, Volume 121, Issue 3, pp. 731 - 736
Background Understanding predictors of clinical remission would assist in clinical management of peanut allergy. Objective We sought to determine the early...
Allergy and Immunology | peanut-specific IgE | sesame | skin prick test | clinical predictors | tree nut | Peanut allergy | TESTS | MANAGEMENT | IGE | RESOLUTION | PREVALENCE | IMMUNOLOGY | SKIN PRICK | NATURAL-HISTORY | peanut allergy | ALLERGY | FOOD CHALLENGES | TREE NUT ALLERGY | YOUNG-CHILDREN | Skin Tests | Humans | Child, Preschool | Infant | Male | Peanut Hypersensitivity - immunology | Food Hypersensitivity - epidemiology | Immunoglobulin E - blood | Eczema - epidemiology | Peanut Hypersensitivity - blood | Female | Remission, Spontaneous | Respiratory Function Tests | Longitudinal Studies | Food allergies | Nuts | Peanuts | Allergies | Children & youth
Allergy and Immunology | peanut-specific IgE | sesame | skin prick test | clinical predictors | tree nut | Peanut allergy | TESTS | MANAGEMENT | IGE | RESOLUTION | PREVALENCE | IMMUNOLOGY | SKIN PRICK | NATURAL-HISTORY | peanut allergy | ALLERGY | FOOD CHALLENGES | TREE NUT ALLERGY | YOUNG-CHILDREN | Skin Tests | Humans | Child, Preschool | Infant | Male | Peanut Hypersensitivity - immunology | Food Hypersensitivity - epidemiology | Immunoglobulin E - blood | Eczema - epidemiology | Peanut Hypersensitivity - blood | Female | Remission, Spontaneous | Respiratory Function Tests | Longitudinal Studies | Food allergies | Nuts | Peanuts | Allergies | Children & youth
Journal Article