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Journal of Nuclear Medicine, ISSN 0161-5505, 05/2015, Volume 56, Issue 5, pp. 778 - 778
One of the most prominent cell populations playing a role in rheumatoid arthritis (RA) is activated fibroblast-like synoviocytes. Among many other proteins,... 
Journal Article
Cancer Cell, ISSN 1535-6108, 03/2017, Volume 31, Issue 3, pp. 396 - 410
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2016, Volume 22, Issue 13, pp. 3286 - 3297
Journal Article
FASEB Journal, ISSN 0892-6638, 08/2006, Volume 20, Issue 10, pp. 1599 - 1610
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 01/2015, Volume 56, pp. 66 - 80
Regulatory T cells (Tregs) expressing FOXP3 are essential for the maintenance of self-tolerance and are deficient in many common autoimmune diseases. Immune... 
Autoimmunity | Graft versus host disease | IL-2 fusion proteins | Regulatory T cells | Cytokine therapy
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 05/2016, Volume 15, Issue 5, pp. 946 - 957
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2014, Volume 56, pp. 66 - 80
Abstract Regulatory T cells (Tregs) expressing FOXP3 are essential for the maintenance of self-tolerance and are deficient in many common autoimmune diseases.... 
Allergy and Immunology | Autoimmunity | Graft versus host disease | IL-2 fusion proteins | Regulatory T cells | Cytokine therapy | NONHUMAN-PRIMATES | IMMUNITY | LOW-DOSE INTERLEUKIN-2 | RECOMBINANT INTERLEUKIN-2 | IMMUNOLOGY | FOXP3 | THERAPY | PHARMACOKINETICS | EXPANSION | EXPRESSION | IMMUNODEFICIENCY | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | Eosinophilia - chemically induced | Recombinant Fusion Proteins - pharmacology | Humans | Macaca fascicularis | Male | T-Lymphocytes, Regulatory - immunology | Dose-Response Relationship, Drug | STAT5 Transcription Factor - metabolism | Forkhead Transcription Factors - metabolism | T-Lymphocyte Subsets - drug effects | Female | Interleukin-2 - analogs & derivatives | Phosphorylation - drug effects | Biomarkers - metabolism | Interleukin-2 - metabolism | Interleukin-2 Receptor alpha Subunit - deficiency | CTLA-4 Antigen - metabolism | Recombinant Proteins - pharmacology | Mice, Knockout | Phenotype | T-Lymphocytes, Regulatory - drug effects | Animals | Interleukin-2 Receptor alpha Subunit - metabolism | Signal Transduction - drug effects | T-Lymphocyte Subsets - metabolism | Interleukin-2 - pharmacology | Lymphocyte Count | Protein Binding | Mice | Proteins | Epigenetic inheritance | T cells | Immunoglobulin G | Medical genetics | PK, pharmacokinetics | GVHD, graft versus host disease
Journal Article
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 12/2018, Volume 95, pp. 1 - 14
Susceptibility to multiple autoimmune diseases is associated with common gene polymorphisms influencing IL-2 signaling and T function, making T -specific... 
Autoimmunity | IL-2 mutein | Cytokine therapy | Immunotherapy | Treg expansion | T(reg) expansion | expansion | FOXP3 EXPRESSION | HOMEOSTASIS | STIMULATION | LOW-DOSE INTERLEUKIN-2 | RECEPTOR | SELF | IMMUNOLOGY | EFFECTOR | RESPONSES | T-reg expansion | EXPANSION | TIGIT | Killer cells | T cells | Immunoglobulin G
Journal Article
SCIENCE TRANSLATIONAL MEDICINE, ISSN 1946-6234, 06/2019, Volume 11, Issue 496, p. eaav5989
Endogenous costimulatory molecules on T cells such as 4-1BB (CD137) can be leveraged for cancer immunotherapy. Systemic administration of agonistic anti-4-1BB... 
PATHWAYS | MEDICINE, RESEARCH & EXPERIMENTAL | IGG | COSTIMULATION | ANTI-CD137 | CARCINOEMBRYONIC ANTIGEN | INDUCTION | MODEL | LYMPHOCYTES | CELL BIOLOGY
Journal Article
Protein Science, ISSN 0961-8368, 01/2006, Volume 15, Issue 1, pp. 14 - 27
Engineered antibodies and their fragments are invaluable tools for a vast range of biotechnological and pharmaceutical applications. However, they are facing... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 11/2006, Volume 108, Issue 11, pp. 4527 - 4527
Abstract Novel in vitro methods for screening of antibody libraries against disease-related antigens have led to the development of powerful protein-based... 
Journal Article
The Journal of Nuclear Medicine, ISSN 0161-5505, 05/2015, Volume 56, Issue 5, p. 778
  One of the most prominent cell populations playing a role in rheumatoid arthritis (RA) is activated fibroblast-like synoviocytes. Among many other proteins,... 
Proteins | Nuclear medicine | Rheumatoid arthritis | Tomography | Protein expression
Journal Article
Journal Article