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Breast Cancer Research and Treatment, ISSN 0167-6806, 7/2019, Volume 176, Issue 1, pp. 141 - 148
To improve breast cancer risk stratification to enable more targeted early detection/prevention strategies that will better balance risks and benefits of... 
Polygenic risk score | Pathology | Mammographic density | Medicine & Public Health | SNPs | Oncology | Breast cancer | Early detection | ONCOLOGY | GENOME-WIDE ASSOCIATION | Prevention | Oncology, Experimental | Mammography | Research | Diagnosis | Health aspects | Risk factors | Cancer | Clinical Trial
Journal Article
Neurobiology of aging, ISSN 0197-4580, 04/2019
The brain's structures and functions arise from a combination of developmental processes and interaction with environmental experiences, beginning in utero and... 
Journal Article
Genetics in medicine : official journal of the American College of Medical Genetics, ISSN 1098-3600, 09/2019
Neurofibromatosis 1 (NF1) is an autosomal dominant condition caused by pathogenic variants of the NF1 gene. A markedly increased risk of breast cancer is... 
Journal Article
Brain research bulletin, ISSN 0361-9230, 4/2016, Volume 122, pp. 1 - 11
Genetic mouse models for Alzheimer’s disease (AD) have been widely used to understand aspects of the biology of the disease, but have had limited success in... 
genetic model | preclinical model | Alzheimer’s disease | mouse model | neuroinflammation | biomarkers | genomics | translational assays
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 05/2017, Volume 114, Issue 19, p. E3839
Journal Article
PLoS Biology, ISSN 1544-9173, 10/2015, Volume 13, Issue 10
  Aging is the major risk factor for neurodegenerative diseases such as Alzheimer's disease, but little is known about the processes that lead to age-related... 
Automation | Physical fitness | Activities of daily living | Exercise | Older people | Aging | Running | Population | Behavior | Alzheimers disease | Experiments | Age
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 2014, Volume 51, Issue 9, pp. 623 - 634
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P1402 - P1402
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P212 - P213
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2017, Volume 114, Issue 19, p. E3839
Various immune response pathways are altered during early, predegenerative stages of glaucoma; however, whether the early immune responses occur secondarily to... 
Glaucoma | Immune response | Profiling | Optic nerve | Transcription | Epidermal growth factor receptors | Astrocytes | Medical treatment | Retina | Complement | Complement component C1q | Retinal ganglion cells | Signal transduction | Elevation | Pathways | Rodents | Complement component C3 | Wld protein | Eye (anatomy) | Mice | Intraocular pressure | Immune system
Journal Article
Brain Research Bulletin, ISSN 0361-9230, 2015, Volume 122, pp. 1 - 11
Highlights • Mouse models have improved our understanding of early-onset Alzheimer's disease. • The field lacks useful models of the more common late-onset... 
Neurology | Genetic model | Alzheimer’s disease | Genomics | Biomarkers | Translational assays | Neuroinflammation | Mouse model | Preclinical model | Alzheimer's disease | Mice | Animals | Alzheimer Disease - genetics | Genetic Testing - methods | Biomarkers - analysis | Disease Models, Animal | Animal behavior | Analysis
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2015
Abstract Evidence suggests that multiple genetic and environmental factors conspire together to increase susceptibility to Alzheimer’s disease (AD). The... 
Neurology | Internal Medicine
Journal Article
Breast Cancer Research, ISSN 1465-5411, 02/2013, Volume 15, Issue 1, pp. 401 - 401
In the previous issue of Breast Cancer Research, Rhiem and colleagues report contralateral breast cancer risks in relatives of BRCA1/2 mutation carriers as... 
ONCOLOGY | BRCA1 Protein - genetics | Genetic Predisposition to Disease | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Pedigree | Humans | Risk Factors | Family | Female | Breast Neoplasms - diagnosis | BRCA2 Protein - genetics | Letter
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 07/2013, Volume 140, Issue 1, p. 135
BRCA1/2 mutation carriers with breast cancer are at high risk of contralateral disease. Such women often elect to have contralateral risk-reducing mastectomy... 
Women | Breast cancer | Analysis | Surgery
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 7/2013, Volume 140, Issue 1, pp. 135 - 142
Journal Article
Journal Article
Annual Review of Neuroscience, ISSN 0147-006X, 07/2012, Volume 35, pp. 153 - 153
Glaucoma is a complex neurodegenerative disorder that is expected to affect 80 million people by the end of this decade. Retinal ganglion cells (RGCs) are the... 
Eye | Glaucoma | Axons | Retinal ganglion cells | Optic nerve | Reviews | Neurodegenerative diseases | Etiology | Nervous system | Pressure | Risk factors
Journal Article
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