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1. Full Text Taxanes versus S-1 as the first-line chemotherapy for metastatic breast cancer (SELECT BC): an open-label, non-inferiority, randomised phase 3 trial
by Takashima, Tsutomu, MD and Mukai, Hirofumi, Dr and Hara, Fumikata, MD and Matsubara, Nobuaki, MD and Saito, Tsuyoshi, MD and Takano, Toshimi, MD and Park, Youngjin, Prof and Toyama, Tatsuya, Prof and Hozumi, Yasuo, MD and Tsurutani, Junji, MD and Imoto, Shigeru, Prof and Watanabe, Takanori, MD and Sagara, Yoshiaki, MD and Nishimura, Reiki, MD and Shimozuma, Kojiro, Prof and Ohashi, Yasuo, Prof and SELECT BC study group and SELECT BC Study Grp and SELECT BC Study Group
The lancet oncology, ISSN 1470-2045, 2016, Volume 17, Issue 1, pp. 90 - 98
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Breast Neoplasms - surgery | Follow-Up Studies | Humans | Middle Aged | Fatigue - chemically induced | Receptors, Estrogen - analysis | Receptors, Progesterone - analysis | Taxoids - therapeutic use | Female | Antineoplastic Agents, Phytogenic - therapeutic use | Liver Neoplasms - secondary | Neutropenia - chemically induced | Taxoids - adverse effects | Antineoplastic Agents, Phytogenic - adverse effects | Tegafur - adverse effects | Tegafur - therapeutic use | Paclitaxel - adverse effects | Survival Rate | Breast Neoplasms - drug therapy | Paclitaxel - therapeutic use | Disease Progression | Oxonic Acid - adverse effects | Disease-Free Survival | Antimetabolites, Antineoplastic - therapeutic use | Oxonic Acid - therapeutic use | Breast Neoplasms - pathology | Antimetabolites, Antineoplastic - adverse effects | Aged | Edema - chemically induced | Receptor, ErbB-2 - analysis | Health Status | Drug Combinations | Antimitotic agents | Medical colleges | Chemotherapy | Product development | Breast cancer | Metastasis | Antineoplastic agents | Cancer | Index Medicus
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2. Full Text Participants in a randomized controlled trial had longer overall survival than non-participants: a prospective cohort study
by Ohno, Shinji and Mukai, Hirofumi and Narui, Kazutaka and Hozumi, Yasuo and Miyoshi, Yasuo and Yoshino, Hiroshi and Doihara, Hiroyoshi and Suto, Akihiko and Tamura, Motoshi and Morimoto, Takashi and Zaha, Hisamitsu and Chishima, Takashi and Nishimura, Reiki and Ishikawa, Takashi and Uemura, Yukari and Ohashi, Yasuo
Breast cancer research and treatment, ISSN 0167-6806, 8/2019, Volume 176, Issue 3, pp. 631 - 635
Medicine & Public Health | Prospective cohort study | Trial effect | Oncology | SELECT BC | Overall survival | Randomized control trial | Life Sciences & Biomedicine | Science & Technology | Humans | Middle Aged | Patient Participation | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Biomarkers, Tumor | Neoplasm Metastasis | Adult | Female | Outcome Assessment, Health Care | Kaplan-Meier Estimate | Survival Rate | Treatment Outcome | Combined Modality Therapy | Oxonic Acid - administration & dosage | Breast Neoplasms - drug therapy | Randomized Controlled Trials as Topic | Taxoids - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Tegafur - administration & dosage | Breast Neoplasms - mortality | Aged | Breast Neoplasms - diagnosis | Neoplasm Staging | Bridged-Ring Compounds - administration & dosage | Drug Combinations | Medical research | Care and treatment | Chemotherapy | Prognosis | Patient outcomes | Clinical trials | Medicine, Experimental | Metastasis | Research | Comparative analysis | Cancer | Index Medicus
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3. Full Text Health-related quality of life, psychological distress, and adverse events in postmenopausal women with breast cancer who receive tamoxifen, exemestane, or anastrozole as adjuvant endocrine therapy: National Surgical Adjuvant Study of Breast Cancer 04 (N-SAS BC 04)
by Takei, Hiroyuki and Ohsumi, Shozo and Shimozuma, Kojiro and Takehara, Megumi and Suemasu, Kimito and Ohashi, Yasuo and Hozumi, Yasuo
Breast cancer research and treatment, ISSN 0167-6806, 5/2012, Volume 133, Issue 1, pp. 227 - 236
Medicine & Public Health | Anastrozole | Adverse event | Oncology | Breast cancer | Exemestane | Tamoxifen | Quality of life | Life Sciences & Biomedicine | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Chemotherapy | Miscellaneous | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Pharmacology. Drug treatments | Psychopathology. Psychiatry | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | Breast Neoplasms - surgery | Triazoles - administration & dosage | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Tamoxifen - administration & dosage | Nitriles - administration & dosage | Depression - chemically induced | Postmenopause | Female | Surveys and Questionnaires | Maintenance Chemotherapy | Chemotherapy, Adjuvant | Carcinoma - drug therapy | Neoplasms, Hormone-Dependent - surgery | Stress, Psychological - chemically induced | Carcinoma - surgery | Treatment Outcome | Breast Neoplasms - drug therapy | Carcinoma - psychology | Androstadienes - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - psychology | Neoplasms, Hormone-Dependent - psychology | Quality of Life | Aged | Neoplasms, Hormone-Dependent - drug therapy | Care and treatment | Oncology, Experimental | Adjuvant treatment | Postmenopausal women | Research | Stress (Psychology) | Cancer | Index Medicus
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4. Full Text Adjuvant tamoxifen and exemestane in early breast cancer (TEAM): a randomised phase 3 trial
by van de Velde, Cornelis JH, Prof and Rea, Daniel, MD and Seynaeve, Caroline, MD and Putter, Hein, Prof and Hasenburg, Annette, Prof and Vannetzel, Jean-Michel, MD and Paridaens, Robert, Prof and Markopoulos, Christos, Prof and Hozumi, Yasuo, MD and Hille, Elysee TM, PhD and Kieback, Dirk G, MD and Asmar, Lina, PhD and Smeets, Jan, BSc and Nortier, Johan WR, Prof and Hadji, Peyman, Prof and Bartlett, John MS, PhD and Jones, Stephen E, MD
The Lancet (British edition), ISSN 0140-6736, 2011, Volume 377, Issue 9762, pp. 321 - 331
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Biological and medical sciences | General aspects | Medical sciences | Tumors | Receptors, Estrogen - metabolism | Adenocarcinoma - pathology | Humans | Middle Aged | Breast Neoplasms - metabolism | Receptors, Progesterone - metabolism | Breast Neoplasms - therapy | Disease-Free Survival | Adenocarcinoma - metabolism | Adenocarcinoma - therapy | Breast Neoplasms - pathology | Antineoplastic Agents, Hormonal - therapeutic use | Tamoxifen - therapeutic use | Aged, 80 and over | Postmenopause | Adult | Breast Neoplasms - mortality | Female | Aged | Androstadienes - therapeutic use | Early Diagnosis | Adenocarcinoma - mortality | Disease | Womens health | Meetings | Data collection | Breast cancer | Mammography | Family medical history | Clinical medicine | Cancer therapies | Index Medicus | Abridged Index Medicus | Ethics | Side effects | Hospitals | thromboembolism | survival | musculoskeletal system | post-menopause | Cancer
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5. Full Text Randomized phase III trial of trastuzumab monotherapy followed by trastuzumab plus docetaxel versus trastuzumab plus docetaxel as first-line therapy in patients with HER2-positive metastatic breast cancer: the JO17360 Trial Group
by Inoue, Kenichi and Inoue, Kenichi and Nakagami, Kazuhiko and Nakagami, Kazuhiko and Mizutani, Mitsuhiro and Mizutani, Mitsuhiro and Hozumi, Yasuo and Hozumi, Yasuo and Fujiwara, Yasuhiro and Fujiwara, Yasuhiro and Masuda, Norikazu and Masuda, Norikazu and Tsukamoto, Fumine and Tsukamoto, Fumine and Saito, Mitsue and Saito, Mitsue and Miura, Shigeto and Miura, Shigeto and Eguchi, Kenji and Eguchi, Kenji and Shinkai, Tetsu and Shinkai, Tetsu and Ando, Masashi and Ando, Masashi and Watanabe, Toru and Watanabe, Toru and Masuda, Noriyuki and Masuda, Noriyuki and Ohashi, Yasuo and Ohashi, Yasuo and Sano, Muneaki and Sano, Muneaki and Noguchi, Shinzaburo and Noguchi, Shinzaburo
Breast cancer research and treatment, ISSN 0167-6806, 1/2010, Volume 119, Issue 1, pp. 127 - 136
Medicine & Public Health | First-line therapy | Docetaxel | Oncology | Metastatic breast cancer | Combination therapy | Trastuzumab | Life Sciences & Biomedicine | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Biological and medical sciences | Medical sciences | Tumors | Receptor, ErbB-2 - biosynthesis | Drug Administration Schedule | Humans | Middle Aged | Proportional Hazards Models | Breast Neoplasms - drug therapy | Disease Progression | Breast Neoplasms - metabolism | Antibodies, Monoclonal, Humanized | Disease-Free Survival | Taxoids - administration & dosage | Neoplasm Metastasis | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Aged, 80 and over | Adult | Female | Aged | Antimitotic agents | Care and treatment | Clinical trials | Breast cancer | Product development | Metastasis | Toy industry | Antineoplastic agents | Index Medicus
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6. Full Text Cost-effectiveness analysis of the introduction of S-1 therapy for first-line metastatic breast cancer treatment in Japan: Results from the randomized phase III SELECT BC trial
by Shiroiwa, Takeru and Fukuda, Takashi and Shimozuma, Kojiro and Mouri, Mitsuko and Hagiwara, Yasuhiro and Kawahara, Takuya and Ohsumi, Shozo and Hozumi, Yasuo and Sagara, Yoshiaki and Ohashi, Yasuo and Mukai, Hirofumi
BMC cancer, ISSN 1471-2407, 11/2017, Volume 17, Issue 1, pp. 773 - 773
Cost-effectiveness analysis | Quality-adjusted life years | Breast neoplasms | Taxoids | Randomized controlled trial | S-1 | Life Sciences & Biomedicine | Oncology | Science & Technology | Evaluation | Care and treatment | Breast cancer | Medical care, Cost of | Index Medicus
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7. Full Text Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics
by Akaike, Takaaki and Ida, Tomoaki and Wei, Fan-Yan and Nishida, Motohiro and Kumagai, Yoshito and Alam, Md. Morshedul and Ihara, Hideshi and Sawa, Tomohiro and Matsunaga, Tetsuro and Kasamatsu, Shingo and Nishimura, Akiyuki and Morita, Masanobu and Tomizawa, Kazuhito and Nishimura, Akira and Watanabe, Satoshi and Inaba, Kenji and Shima, Hiroshi and Tanuma, Nobuhiro and Jung, Minkyung and Fujii, Shigemoto and Watanabe, Yasuo and Ohmuraya, Masaki and Nagy, Péter and Feelisch, Martin and Fukuto, Jon M and Motohashi, Hozumi
Nature communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1177 - 15
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Recombinant Proteins - metabolism | Cysteine - analogs & derivatives | Oxidation-Reduction | Humans | Hydrogen Sulfide - chemistry | Sulfides - chemistry | Mitochondria - metabolism | Cysteine - chemistry | Mice, Knockout | Tandem Mass Spectrometry | Animals | Energy Metabolism | Disulfides - chemistry | Computer Simulation | Escherichia coli - metabolism | Sulfhydryl Compounds - chemistry | Mice | Protein Processing, Post-Translational | Amino Acyl-tRNA Synthetases - metabolism | Sulfide | Enzymes | Oxidative stress | Cysteine | Translation | Biosynthesis | tRNA Cys | Mammals | Mammalian cells | Hydrogen sulfide | Proteins | Signaling | Mitochondria | Bioenergetics | E coli | Post-translation | Physiology | Disruption | Aberration | Chemical synthesis | Cysteine-tRNA ligase | Index Medicus
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8. Probiotic beverage with soy isoflavone consumption for breast cancer prevention: A case-control study
by Toi, Masakazu and Hirota, Saya and Tomotaki, Ai and Sato, Nobuaki and Hozumi, Yasuo and Anan, Keisei and Nagashima, Takeshi and Tokuda, Yutaka and Masuda, Norikazu and Ohsumi, Shozo and Ohno, Shinji and Takahashi, Masato and Hayashi, Hironori and Yamamoto, Seiichiro and Ohashi, Yasuo
Current nutrition and food science, ISSN 1573-4013, 2013, Volume 9, Issue 3, pp. 194 - 200
Breast cancer | Soy isoflavones | Lactobacillus casei shirota | Probiotic beverage
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9. Full Text Anastrozole versus tamoxifen as adjuvant therapy for Japanese postmenopausal patients with hormone-responsive breast cancer: efficacy results of long-term follow-up data from the N-SAS BC 03 trial
by Aihara, Tomohiko and Yokota, Isao and Hozumi, Yasuo and Aogi, Kenjiro and Iwata, Hiroji and Tamura, Motoshi and Fukuuchi, Atsushi and Makino, Haruhiko and Kim, Ryungsa and Andoh, Masashi and Tsugawa, Koichiro and Ohno, Shinji and Yamaguchi, Takuhiro and Ohashi, Yasuo and Watanabe, Toru and Takatsuka, Yuichi and Mukai, Hirofumi
Breast cancer research and treatment, ISSN 0167-6806, 11/2014, Volume 148, Issue 2, pp. 337 - 343
Medicine & Public Health | Anastrozole | Oncology | Breast cancer | Tamoxifen | Adjuvant therapy | Hormonal therapy | Life Sciences & Biomedicine | Science & Technology | Receptors, Estrogen - metabolism | Prognosis | Follow-Up Studies | Humans | Middle Aged | Receptor, ErbB-2 - metabolism | Neoplasm Recurrence, Local - drug therapy | Neoplasm Recurrence, Local - mortality | Immunoenzyme Techniques | Receptors, Progesterone - metabolism | Neoplasm Recurrence, Local - pathology | Antineoplastic Agents, Hormonal - therapeutic use | Aged, 80 and over | Biomarkers, Tumor - metabolism | Adult | Female | Triazoles - therapeutic use | Survival Rate | Breast Neoplasms - drug therapy | Breast Neoplasms - pathology | Tamoxifen - therapeutic use | Breast Neoplasms - mortality | Aged | Neoplasm Staging | Nitriles - therapeutic use | Care and treatment | Adjuvant treatment | Postmenopausal women | Hormones | Comparative analysis | Health aspects | Cancer | Index Medicus
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10. Full Text Health-related quality of life and psychological distress of breast cancer patients after surgery during a phase III randomized trial comparing continuation of tamoxifen with switching to anastrozole after adjuvant tamoxifen for 1–4 years: N-SAS BC 03
by Ohsumi, Shozo and Shimozuma, Kojiro and Ohashi, Yasuo and Shinji, Megumi and Hozumi, Yasuo and Mukai, Hirofumi and Takatsuka, Yuichi and Aihara, Tomohiko
Breast cancer research and treatment, ISSN 0167-6806, 5/2011, Volume 127, Issue 1, pp. 143 - 152
Aromatase inhibitor | Medicine & Public Health | Oncology | Breast cancer | Adjuvant endocrine therapy | Tamoxifen | Quality of life | Life Sciences & Biomedicine | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Miscellaneous | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Psychopathology. Psychiatry | Biological and medical sciences | Medical sciences | Tumors | Breast Neoplasms - surgery | Humans | Middle Aged | Treatment Outcome | Breast Neoplasms - drug therapy | Breast Neoplasms - psychology | Antineoplastic Agents, Hormonal - therapeutic use | Tamoxifen - therapeutic use | Quality of Life | Female | Aged | Nitriles - therapeutic use | Triazoles - therapeutic use | Care and treatment | Cancer patients | Adjuvant treatment | Postmenopausal women | Product development | Stress (Psychology) | Cancer | Index Medicus
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11. Full Text Overall survival of participants compared to non-participants in a randomized-controlled trial (SELECT BC): A prospective cohort study
by Narui, Kazutaka and Ohno, Shinji and Mukai, Hirofumi and Hozumi, Yasuo and Miyoshi, Yasuo and Yoshino, Hiroshi and Doihara, Hiroyoshi and Suto, Akihiko and Tamura, Motoshi and Morimoto, Takashi and Zaha, Hisamitsu and Chishima, Takashi and Nishimura, Reiki and Ishikawa, Takashi and Uemura, Yukari and Ohashi, Yasuo and SELECT BC study group
Journal of clinical oncology, ISSN 0732-183X, 05/2016, Volume 34, Issue 15_suppl, pp. 2527 - 2527
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12. Full Text Factors affecting enrollment in randomized controlled trials conducted for patients with metastatic breast cancer
by Ohsumi, Shozo and Mukai, Hirofumi and Takahashi, Masato and Hozumi, Yasuo and Akabane, Hiromitsu and Park, Youngjin and Tokunaga, Eriko and Takashima, Tsutomu and Watanabe, Takanori and Sagara, Yoshiaki and Kaneko, Tetsuji and Ohashi, Yasuo
Japanese journal of clinical oncology, ISSN 0368-2811, 08/2020, Volume 50, Issue 8, pp. 873 - 881
Life Sciences & Biomedicine | Oncology | Science & Technology | Index Medicus
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