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Nature Biotechnology, ISSN 1087-0156, 01/2010, Volume 28, Issue 1, pp. 63 - 70
Phosphodiesterase 4 (PDE4), the primary cAMP-hydrolyzing enzyme in cells, is a promising drug target for a wide range of conditions. Here we present seven... 
CAMP-SPECIFIC PHOSPHODIESTERASE | PHOSPHORYLATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROTEIN-KINASE | GENE COMPOSER | SUNCUS-MURINUS | AMP-SPECIFIC PHOSPHODIESTERASE | INHIBITORS | CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE | ROLIPRAM BINDING | ANTIDEPRESSANT DRUGS | Phosphodiesterase Inhibitors - therapeutic use | Phosphodiesterase Inhibitors - adverse effects | Humans | Molecular Sequence Data | Crystallography, X-Ray | Structure-Activity Relationship | Benzhydryl Compounds - chemistry | Benzhydryl Compounds - adverse effects | Phenylurea Compounds - adverse effects | Phenylurea Compounds - chemistry | Drug Design | Phosphodiesterase 4 Inhibitors | Behavior, Animal - drug effects | Biological Assay | Phosphodiesterase Inhibitors - chemistry | Benzhydryl Compounds - therapeutic use | Cyclic Nucleotide Phosphodiesterases, Type 4 - chemistry | Disease Models, Animal | Allosteric Regulation - drug effects | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Catalytic Domain | Models, Molecular | Phenylurea Compounds - therapeutic use | Phosphodiesterase Inhibitors - pharmacology | Vomiting - drug therapy | Cognition - drug effects | Animals | Benzhydryl Compounds - pharmacology | Mice | Phenylurea Compounds - pharmacology | Kinetics | Care and treatment | Schizophrenia | Physiological aspects | Genetic aspects | Cellular signal transduction | Cyclic adenylic acid | Research | Phosphodiesterases | Enzymes | Biotechnology | Cellular biology | Molecular biology | Cognitive ability | Crystal structure | Index Medicus
Journal Article
Analytical and Bioanalytical Chemistry, ISSN 1618-2642, 1/2012, Volume 402, Issue 3, pp. 1183 - 1198
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 08/2000, Volume 182, Issue 15, p. 4198
  In bacteria, phospholipids are synthesized on the inner leaflet of the cytoplasmic membrane and must translocate to the outer leaflet to propagate a bilayer.... 
Proteins | Enzymes | Membranes | Microbiology | Lipids | Bacteria | Metabolism | Cells
Journal Article
Journal Article
01/2000, ISBN 0599782323
In bacteria, phospholipids are synthesized on the inner leaflet of the cytoplasmic membrane and must translocate to the outer leaflet to create a bilayer. We... 
Cellular biology | Molecular biology
Dissertation
Thesis (Ph. D.)--University of Wisconsin--Madison, 2000. Includes bibliographical references. Also available on the Internet. 
Dissertation
Thesis (Ph. D.)--University of Wisconsin--Madison, 2000. eContent provider-neutral record in process. Description based on print version record. Includes... 
Dissertation
Current Biology, ISSN 0960-9822, 03/2000, Volume 10, Issue 5, pp. 241 - 252
Background: A long-standing problem in understanding the mechanism by which the phospholipid bilayer of biological membranes is assembled concerns how... 
Journal Article
Biochemistry, ISSN 0006-2960, 04/1997, Volume 36, Issue 16, pp. 4969 - 4978
Journal Article
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