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Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 14
Hematopoietic stem cell (HSC) gene therapy is being evaluated for hemoglobin disorders including sickle cell disease (SCD). Therapeutic globin vectors have... 
CD34 antigen | Splicing | Stem cells | Disorders | Hemoglobin | Gene therapy | Ribonucleic acid--RNA | Gene expression | Sickle cell disease | Hematopoietic stem cells | Hemopoiesis
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 03/2018, Volume 19, Issue 3, p. 681
Journal Article
British Journal of Haematology, ISSN 0007-1048, 10/2019, Volume 187, Issue 1, pp. 117 - 123
Summary Vibration controlled transient elastography (VCTE) is validated for the evaluation of hepatic fibrosis in different liver diseases. Sickle cell liver... 
vibration controlled transient elastography | liver biopsy | sickle cell liver disease | sickle cell hepatopathy | sickle cell disease | Sickle cell anemia | Liver diseases | Evaluation | Vibration | Hepatocytes | Biopsy | Correlation analysis | Liver | Fibrosis | Histology | Sickle cell disease | Disease control
Journal Article
by Abolfathi, Bela and Aguado, D.S and Aguilar, Gabriela and Prieto, Carlos Allende and Almeida, Andres and Ananna, Tonima Tasnim and Anders, Friedrich and Anderson, Scott F and Andrews, Brett H and Anguiano, Borja and Aragón-Salamanca, Alfonso and Argudo-Fernández, Maria and Armengaud, Eric and Ata, Metin and Aubourg, Eric and Avila-Reese, Vladimir and Badenes, Carles and Bailey, Stephen and Balland, Christophe and Barger, Kathleen A and Barrera-Ballesteros, Jorge and Bartosz, Curtis and Bastien, Fabienne and Bates, Dominic and Baumgarten, Falk and Bautista, Julian and Beaton, Rachael and Beers, Timothy C and Belfiore, Francesco and Bender, Chad F and Bernardi, Mariangela and Bershady, Matthew A and Beutler, Florian and Bird, Jonathan C and Bizyaev, Dmitry and Blanc, Guillermo A and Blanton, Michael R and Blomqvist, Michael and Bolton, Adam S and Boquien, Médéric and Borissova, Jura and Bovy, Jo and Bradna Diaz, Christian Andres and Nielsen Brandt, William and Brinkmann, Jonathan and Brownstein, Joel R and Bundy, Kevin and Burgasser, Adam J and Burtin, Etienne and Busca, Nicolás G and Canãs, Caleb I and Cano-Diáz, Mariana and Cappellari, Michele and Carrera, Ricardo and Casey, Andrew R and Sodi, Bernardo Cervantes and Chen, Yanping and Cherinka, Brian and Chiappini, Cristina and Choi, Peter Doohyun and Chojnowski, Drew and Chuang, Chia-Hsun and Chung, Haeun and Clerc, Nicolas and Cohen, Roger E and Comerford, Julia M and Comparat, Johan and Do Nascimento, Janaina Correa and Da Costa, Luiz and Cousinou, Marie-Claude and Covey, Kevin and Crane, Jeffrey D and Cruz-Gonzalez, Irene and Cunha, Katia and Ilha, Gabriele Da Silva and Damke, Guillermo J and Darling, Jeremy and Davidson, James W and Dawson, Kyle and De Icaza Lizaola, Miguel Angel C and MacOrra, Axel De La and De La Torre, Sylvain and De Lee, Nathan and Sainte Agathe, Victoria De and Deconto MacHado, Alice and Dell'Agli, Flavia and Delubac, Timotheé and Diamond-Stanic, Aleksandar M and Donor, John and Downes, Juan José and Drory, Niv and Mas Des Bourboux, Hélion Du and Duckworth, Christopher J and Dwelly, Tom and Dyer, Jamie and Ebelke, Garrett and Eigenbrot, Arthur Davis and Eisenstein, Daniel J and Elsworth, Yvonne P and Emsellem, Eric and ... and Brookhaven National Laboratory (BNL), Upton, NY (United States)
Astrophysical Journal, Supplement Series, ISSN 0067-0049, 04/2018, Volume 235, Issue 2, p. 42
The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since 2014 July. This paper describes the second data release from this... 
surveys | catalogs | atlases | NEARBY GALAXIES | HISTORIES | SPIDERS | TELESCOPE | METALLICITY | SDSS-IV MANGA | PIPE3D | ASTRONOMY & ASTROPHYSICS | MASS | PIPELINE | Cosmology and Extra-Galactic Astrophysics | Physics | Astrophysics | Surveys | ASTRONOMY AND ASTROPHYSICS | Atlases
Journal Article
Blood Cells, Molecules and Diseases, ISSN 1079-9796, 07/2019, Volume 77, pp. 12 - 16
Benign ethnic neutropenia (BEN), defined by neutrophil count <1.5 k/μL in the absence of other causes, is an asymptomatic condition more commonly observed in... 
Leukopenia | DARC | Benign ethnic neutropenia BEN | BONE-MARROW | SEX | HEMATOLOGY | AGE | Hypertension | Aged | Clinics | Neutropenia
Journal Article
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, ISSN 1083-8791, 3/2016, Volume 22, Issue 3, pp. 397 - 398
Journal Article
Experimental Hematology, ISSN 0301-472X, 06/2018, Volume 62, pp. 7 - 16.e1
Journal Article
Gastroenterology, ISSN 0016-5085, 05/2018, Volume 154, Issue 6, pp. S-1216 - S-1217
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 1172 - 1172
Abstract Ameliorating hemoglobin disorders such as sickle cell disease (SCD) using hematopoietic stem cell (HSC) gene therapy is under development. Unlike in... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 3404 - 3404
Abstract Abstract Background: Hematopoietic progenitor cell (HPC) transplantation can cure sickle cell disease (SCD). Anonmyeloablative conditioning regimen... 
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e104022
Efficient ex vivo transduction of hematopoietic stem cells (HSCs) is encumbered by differentiation which reduces engraftment. We hypothesized that inhibiting... 
FETAL-HEMOGLOBIN LEVELS | REPOPULATING CELLS | MULTIDISCIPLINARY SCIENCES | HEMATOPOIETIC STEM-CELLS | IN-VIVO | DISEASE | SELF-RENEWAL | GENE-THERAPY | MYELODYSPLASTIC SYNDROMES | IMMUNODEFICIENCY | VECTOR | Humans | Male | Transplantation, Heterologous | DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors | Hematopoietic Stem Cells - immunology | Antigens, CD34 - immunology | Antimetabolites, Antineoplastic - pharmacology | Lentivirus - genetics | Hematopoietic Stem Cell Mobilization | Hematopoietic Stem Cells - drug effects | Gene Expression | Transduction, Genetic | Azacitidine - analogs & derivatives | Graft Survival | Mice, SCID | Azacitidine - pharmacology | DNA (Cytosine-5-)-Methyltransferases - genetics | Granulocyte Colony-Stimulating Factor - pharmacology | Animals | Cell Differentiation - drug effects | Hematopoietic Stem Cells - cytology | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | Hematopoietic Stem Cell Transplantation - methods | Primary Cell Culture | DNA (Cytosine-5-)-Methyltransferases - immunology | Genetic Vectors | Antigens, CD34 - genetics | Cell proliferation | Heart | Flow cytometry | Severe combined immunodeficiency | Xenotransplantation | Differentiation (biology) | Stem cell transplantation | Transplantation | Hematopoietic stem cells | Cell adhesion & migration | Allografts | Efficiency | Consent | Rodents | Human immunodeficiency virus--HIV | Xenografts | DNA methylation | Inhibition | Pretreatment | Sickle cell disease | Deoxyribonucleic acid--DNA | CD34 antigen | Cytokines | Hematology | Research & development--R&D | Exposure | Cell differentiation | Equivalence | Plasmids | Stem cells | Epigenetics | DNA methyltransferase | Diabetes | Kidney diseases | 5-aza-2'-deoxycytidine | Research & development | Deoxyribonucleic acid | R&D | HIV | DNA | Human immunodeficiency virus
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 3506 - 3506
Abstract Current gene therapy approaches for treatment of hemoglobinopathies involve viral transduction of hematopoietic stem cells with antisickling globin... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 2483 - 2483
Abstract Hematopoietic stem cell transplantation (HSCT) is the only curative option for patients with sickle cell disease (SCD). HLA-matched sibling HSCT has... 
Journal Article
Experimental Hematology, ISSN 0301-472X, 02/2016, Volume 44, Issue 2, p. 106
Unlike cell lines, human hematopoietic stem cells (HSCs) are less efficiently transduced with HIV-1 vectors, potentially limiting this approach. To investigate... 
Health aspects | Hematopoietic stem cells
Journal Article
20.