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Clinical Cancer Research, ISSN 1078-0432, 07/2017, Volume 23, Issue 14, pp. 3711 - 3720
Purpose: To explore whether a cross-talk exists between PARP inhibition and PD-L1/PD-1 immune checkpoint axis, and determine whether blockade of PD-L1/PD-1... 
CELL LUNG-CANCER | BREAST-CANCER | OVEREXPRESSION | ACTIVATION | THERAPY | PEMBROLIZUMAB | ONCOLOGY | OVARIAN-CANCER | PROVIDES | COMBINATION | CHEMOTHERAPY | Tumor Microenvironment - drug effects | Poly (ADP-Ribose) Polymerase-1 - immunology | Breast Neoplasms - immunology | Humans | Poly(ADP-ribose) Polymerase Inhibitors - immunology | Lymphocytes, Tumor-Infiltrating - drug effects | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Breast Neoplasms - drug therapy | Poly (ADP-Ribose) Polymerase-1 - antagonists & inhibitors | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | Tumor Microenvironment - immunology | Xenograft Model Antitumor Assays | Immunosuppression | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Female | Mice | Gene Expression Regulation, Neoplastic - drug effects | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Cell culture | Flow cytometry | Biotechnology | Animal models | PD-1 protein | Immunoblotting | Lymphocytes T | Immunity | Anticancer properties | Lymphocytes | Xenografts | Tumor-infiltrating lymphocytes | Tumor cells | Poly(ADP-ribose) polymerase | Breast cancer | Tumor cell lines | Inhibitors | Immune checkpoint | Experimental design | PD-L1 protein | Cell lines | Breast | In vivo methods and tests | Tumors | Cancer
Journal Article
Nature Communications, ISSN 2041-1723, 08/2016, Volume 7, Issue 1, p. 12632
Extracellular interaction between programmed death ligand-1 (PD-L1) and programmed cell death protein-1 (PD-1) leads to tumour-associated immune escape. Here... 
EPITHELIAL-MESENCHYMAL TRANSITION | B7 FAMILY-MEMBER | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | N-LINKED GLYCANS | DEGRADATION | PROMOTES TUMORIGENESIS | PD-1 | CANCER | EXPRESSION | Phosphorylation | Breast Neoplasms - immunology | Humans | Antineoplastic Agents - therapeutic use | Lymphocyte Activation - immunology | Ubiquitination | beta-Transducin Repeat-Containing Proteins - metabolism | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Female | Antineoplastic Agents - pharmacology | Gefitinib | Breast - pathology | Tumor Escape - immunology | Programmed Cell Death 1 Receptor - metabolism | Epidermal Growth Factor - metabolism | Glycosylation | B7-H1 Antigen - immunology | Breast Neoplasms - drug therapy | Glycogen Synthase Kinase 3 beta - metabolism | Immunologic Surveillance - immunology | Xenograft Model Antitumor Assays | B7-H1 Antigen - metabolism | Animals | Breast Neoplasms - pathology | Quinazolines - therapeutic use | Protein Stability - drug effects | Cell Line, Tumor | T-Lymphocytes - immunology | Mice | Mice, Inbred BALB C | Quinazolines - pharmacology | Animal models | PD-1 protein | Lymphocytes T | Kinases | Inactivation | Immunity | Proteins | Signal transduction | Epidermal growth factor | Growth factors | Deactivation | Glycogen | Mortality | Glycogen synthase kinase 3 | Breast cancer | Immunosuppression | Cell death | PD-L1 protein | Ligands | Cancer | Tumors | Apoptosis
Journal Article
Biogeosciences Discussions, ISSN 1810-6285, 01/2018, pp. 1 - 41
Abstract. Observations show that soil microorganisms can survive periods of aridity and recover rapidly after wetting events. This behavior can be explained by... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2019, Volume 294, Issue 43, pp. 15711 - 15723
Journal Article
Journal of the American Geriatrics Society, ISSN 0002-8614, 12/2019, Volume 67, Issue 12, pp. 2482 - 2489
OBJECTIVES Polypharmacy may affect frailty, a common and costly condition among older adults. Frailty prevalence is elevated among racial/ethnic minorities and... 
aging health | frailty | epidemiology | cohort study | polypharmacy
Journal Article
Astrophysical Journal, Supplement Series, ISSN 0067-0049, 08/2013, Volume 207, Issue 2, pp. 24 - 23
Journal Article