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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2010, Volume 107, Issue 22, pp. 10280 - 10284
Although multiple follicles are present in mammalian ovaries, most of them remain dormant for years or decades. During reproductive life, some follicles are... 
Kidneys | Germ cells | Developmental biology | Granulosa cells | Transplantation | Mice | Ovaries | Follicles | Oocytes | Tissue grafting | Phosphatidylinositol-3-kinase | Phosphatase with TENsin homology deleted in chromosome 10 | Intracellular signaling | Infertility treatment | Oocyte maturation | phosphatase with TENsin homology deleted in chromosome 10 | OOCYTE GROWTH | INITIATES FOLLICULOGENESIS | RAT | phosphatidylinositol-3-kinase | MULTIDISCIPLINARY SCIENCES | PTEN | PRIMORDIAL FOLLICLES | TRANSPLANTATION | TRANSITION | CELL FACTOR | MOUSE OOCYTES | intracellular signaling | oocyte maturation | IN-VITRO FERTILIZATION | infertility treatment | Animals, Newborn | Humans | Male | Transplantation, Heterologous | Phosphatidylinositol 3-Kinases - metabolism | Pregnancy | Oocytes - cytology | PTEN Phosphohydrolase - antagonists & inhibitors | Ovarian Follicle - drug effects | Animals | Oocytes - physiology | Signal Transduction - drug effects | Embryo Transfer | Forkhead Transcription Factors - metabolism | Ovarian Follicle - physiology | Oocytes - drug effects | Female | Ovary - transplantation | Forkhead Box Protein O3 | In Vitro Techniques | Ovarian Follicle - cytology | Proto-Oncogene Proteins c-akt - metabolism | Organometallic Compounds - pharmacology | Physiological aspects | Research | Ovulation | Stem cells | Biological Sciences
Journal Article
Endocrine Reviews, ISSN 0163-769X, 2000, Volume 21, Issue 2, pp. 200 - 214
Journal Article
Current Biology, ISSN 0960-9822, 11/2014, Volume 24, Issue 21, pp. R1040 - R1042
Activation of a limited pool of diminishing ovarian follicles determines women's reproductive lifespan. A recent rodent study describes the role of mTOR... 
ACTIVATION | OVARIAN-FOLLICLES | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRIMORDIAL FOLLICLES | GROWTH-FACTOR | FOLLICULOGENESIS | MOUSE OVARY | CELL BIOLOGY | Female | Animals | Oocytes - growth & development | Ovarian Follicle - physiology
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 03/2004, Volume 18, Issue 3, pp. 653 - 665
Growth differentiation factor-9 (GDF-9) is an oocyte-derived growth factor and a member of the TGF-β superfamily that includes TGF-β, activin, and bone... 
ALK7 SIGNALS | BONE MORPHOGENETIC PROTEIN | MAD-RELATED PROTEIN | ENDOCRINOLOGY & METABOLISM | OSTEOGENIC PROTEIN-1 | FOLLICULAR-GROWTH | TGF-BETA RECEPTOR | OVARIAN GRANULOSA-CELLS | IDENTIFICATION | HOMOLOG GDF-9B | LUTEAL CELLS | Phosphorylation | Receptors, Transforming Growth Factor beta - genetics | Trans-Activators - drug effects | Protein-Serine-Threonine Kinases | Activin Receptors - drug effects | Activins - metabolism | COS Cells - drug effects | Activin Receptors - genetics | Granulosa Cells - drug effects | Granulosa Cells - metabolism | COS Cells - metabolism | DNA-Binding Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Bone Morphogenetic Proteins - metabolism | Growth Differentiation Factor 9 | Trans-Activators - genetics | Female | Smad7 Protein | Promoter Regions, Genetic | Signal Transduction | Smad6 Protein | Cells, Cultured | DNA-Binding Proteins - drug effects | Rats | Activin Receptors, Type I - metabolism | DNA-Binding Proteins - genetics | Activin Receptors, Type I - genetics | Rats, Sprague-Dawley | Activin Receptors, Type I - drug effects | Transforming Growth Factor beta - pharmacology | Bone Morphogenetic Protein 15 | Smad3 Protein | Activin Receptors - metabolism | Animals | Activins - pharmacology | Receptors, Transforming Growth Factor beta - drug effects | Receptors, Transforming Growth Factor beta - metabolism | Intercellular Signaling Peptides and Proteins - pharmacology | Smad Proteins | Trans-Activators - metabolism | RNA, Small Interfering | Transforming Growth Factor beta - metabolism | Smad2 Protein
Journal Article
Science, ISSN 0036-8075, 11/2005, Volume 310, Issue 5750, pp. 996 - 999
Journal Article
Journal Article
Journal Article
Current Opinion in Obstetrics and Gynecology, ISSN 1040-872X, 06/2016, Volume 28, Issue 3, pp. 217 - 222
Journal Article
Journal Article
Science, ISSN 0036-8075, 1/2002, Volume 295, Issue 5555, pp. 671 - 674
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e49328
Studies using animal models demonstrated the importance of autocrine/paracrine factors secreted by preimplantation embryos and reproductive tracts for... 
HUMAN OOCYTES | PREIMPLANTATION EMBRYO | FERTILIZATION | IMPLANTATION | NEUROTROPHIC FACTOR | MULTIDISCIPLINARY SCIENCES | RANDOMIZED CLINICAL-TRIAL | MOUSE EMBRYOS | IVF | ALPHA | EXPRESSION | Zygote - cytology | Humans | Blastocyst - metabolism | Gene Expression Regulation, Developmental - drug effects | Intercellular Signaling Peptides and Proteins - genetics | Receptors, Cell Surface - metabolism | Blastocyst - cytology | Autocrine Communication - drug effects | Nuclear Transfer Techniques | Blastocyst - drug effects | Intercellular Signaling Peptides and Proteins - metabolism | Zygote - drug effects | Cryopreservation | Intercellular Signaling Peptides and Proteins - pharmacology | Paracrine Communication - drug effects | Culture Media - pharmacology | Fluorescent Antibody Technique | Adult | Female | Ligands | Zygote - growth & development | Embryonic Development - drug effects | Endometrium - metabolism | Embryonic stem cells | Embryonic development | Epidermal growth factor | Reproductive health | In vitro fertilization | Cell culture | Brain | Embryo cells | Neuronal-glial interactions | Signal transduction | Fibroblasts | Growth factors | Medical treatment | Gynecology | Cultures | Blastocysts | Gene expression | Insulin | Embryos | Embryonic growth stage | Embryo transfer | Human performance | Infertility | Stem cells | Combined treatment | Animal models | Media (culture) | Insulin-like growth factor I | Clinical trials | Biology | Insulin-like growth factors | Promotion | Macrophages | Oocytes | Embryogenesis | Allografts | Granulocytes | Colony-stimulating factor |