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Nature Genetics, ISSN 1061-4036, 07/2009, Volume 41, Issue 7, pp. 783 - 792
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2006, Volume 103, Issue 45, pp. 16870 - 16875
It is generally believed that shutting down the kinase activity of BCR-ABL by imatinib will completely inhibit its functions, leading to inactivation of its... 
Myeloid cells | Leukemia | Medical treatment | Stem cells | Cultured cells | Mice | Blast crisis | Chronic myeloid leukemia | Medical cures | Blood | Dasatinib | Imatinib | SRC kinases | CHRONIC MYELOGENOUS LEUKEMIA | GRANULOCYTE-MACROPHAGE PROGENITORS | ABL TYROSINE KINASE | BLAST-CRISIS | MULTIDISCIPLINARY SCIENCES | imatinib | CHRONIC MYELOID-LEUKEMIA | dasatinib | PHILADELPHIA-CHROMOSOME | ACUTE LYMPHOBLASTIC-LEUKEMIA | CLINICAL RESISTANCE | INHIBITOR | MUTANT BCR-ABL | Burkitt Lymphoma - enzymology | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Antineoplastic Agents - therapeutic use | Thiazoles - therapeutic use | src-Family Kinases - deficiency | Blast Crisis - enzymology | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | src-Family Kinases - metabolism | Burkitt Lymphoma - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - enzymology | B-Lymphocytes - enzymology | Mice, Inbred C57BL | Piperazines - therapeutic use | Cell Transformation, Neoplastic - metabolism | Imatinib Mesylate | Mice, Knockout | Animals | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Fusion Proteins, bcr-abl - antagonists & inhibitors | Cell Line, Tumor | Mice, Inbred BALB C | Benzamides | src-Family Kinases - genetics | Neoplastic Stem Cells - enzymology | Kinases | Rodents | Cells | Biological Sciences
Journal Article
Nature Genetics, ISSN 1061-4036, 05/2004, Volume 36, Issue 5, pp. 453 - 461
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2006, Volume 1, Issue 1, p. e18
Background. A somatic activating mutation (V617F) in the JAK2 tyrosine kinase was recently discovered in the majority of patients with polycythemia vera (PV),... 
BIOLOGY | Erythropoiesis | Humans | Polycythemia Vera - blood | Polycythemia Vera - genetics | Primary Myelofibrosis - pathology | Janus Kinase 2 - metabolism | Bone Marrow Transplantation | Janus Kinase 2 - antagonists & inhibitors | Disease Models, Animal | Recombinant Proteins - metabolism | Transduction, Genetic | Mice, Inbred C57BL | Janus Kinase 2 - genetics | Primary Myelofibrosis - etiology | Polycythemia Vera - enzymology | Leukocytosis - etiology | Recombinant Proteins - genetics | Mice, Knockout | Point Mutation | Animals | Platelet Count | Protein Kinase Inhibitors - therapeutic use | Polycythemia Vera - drug therapy | Mice | Mice, Inbred BALB C | Enzyme Activation | Leukocytosis - blood | Amino Acid Substitution | Tyrosine | Erythropoietin | Polycythemia | Bone marrow | Hemoglobin | Transplantation | Therapy | Splenomegaly | Laboratories | Syngeneic grafts | Pathogenesis | Leukemia | Hematocrit | Bone marrow transplantation | Oncology | Polycythemia vera | Kinases | Bleeding | Signal transduction | Granulocytes | Janus kinase 2 | Thrombocytosis | Inbreeding | Megakaryocytes | Protein-tyrosine kinase | Hck protein | Spleen | Imatinib | Myelofibrosis | Complications | Colonies | Abnormalities | Patients | Thrombosis | Hemopoiesis | Leukocytosis | Inhibitors | Fibrosis | Neutrophilia | Mutation | Hematopoietic system | Platelets | Cancer
Journal Article
MATEC Web of Conferences, ISSN 2261-236X, 10/2016, Volume 80, p. 2015
Multi-level approach has been used to simulate the thermal deformation of aluminium alloy at different temperature and strain rate. The crystal plasticity... 
Stress concentration | Aluminum base alloys | Constitutive relationships | Computer simulation | Deformation mechanisms | Tensile tests | Finite element method | Simulation | Evolution | Plastic properties | Mathematical models | Continuum damage mechanics | Thermodynamic properties | Damage | Strain concentration | Constitutive equations | Strain rate | Shear strain
Conference Proceeding
Cell Death and Differentiation, ISSN 1350-9047, 2019, Volume 26, Issue 10, pp. 1929 - 1941
Journal Article
by Zhu, JM and Hong, YG and Zada, S and Hu, Z and Wang, H
FRONTIERS IN MICROBIOLOGY, ISSN 1664-302X, 10/2018, Volume 9, p. 2503
Phytoplankton and bacterioplankton play significant roles in estuarine systems. It is important to demonstrate the spatial variability of bacterial and... 
BACTERIA | MICROBIOLOGY | co-acclimation | FRESH-WATER | SEA | network | BIOGEOCHEMICAL CYCLES | SALINITY GRADIENT | estuary | bacterioplankton | phytoplankton | DYNAMICS | NITROGEN | SP-NOV | DIVERSITY | COASTAL WATERS | Estuaries | Phytoplankton | Research | Microbial colonies
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 10/2018, Volume 19, Issue 10, p. 2940
Journal Article