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Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2019, Volume 517, Issue 1, p. 77
Intra-neuronal [alpha]-synuclein ([alpha]SNCA) aggregation are the leading cause of dopaminergic neuron degeneration in Parkinson's disease (PD). Most PD... 
Electrical engineering | Anopheles | Genetic vectors | Gene mutations | Neurons | Genes | Genetic research | Research institutes | Gene therapy | Gene expression | Health aspects | Medical imaging equipment
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2017, Volume 19, Issue suppl_6, pp. vi51 - vi51
The microenvironment of malignant glioma is characterized by a series of reactive stromal cells with an abundance of inflammatory mediators, and proteolytic... 
Abstracts
Journal Article
Journal Article
Nanoscale, ISSN 2040-3364, 01/2019, Volume 11, Issue 17, pp. 8102 - 8109
The proof-of-concept strategy in this study based on biodegradable and biocompatible self-assembling fluorescent virus-like particle/RNAi nanocomplexes... 
Bioengineering | Brain | Peptides | Biodegradability | Escherichia coli | Brain cancer | Fluorescence | Viruses | DNA repair | Chemotherapy | Biocompatibility | Repair | Growth factors | Deoxyribonucleic acid--DNA | Tumors
Journal Article
Biomaterials, ISSN 0142-9612, 2012, Volume 34, Issue 8, pp. 2142 - 2155
Abstract Current chemotherapeutic agents do not only kill tumor cells but also induce systemic toxicity that significantly limits their dosage. Focused... 
Advanced Basic Science | Dentistry | Focused ultrasound (FUS) | Blood–brain barrier (BBB) | Chemotherapy | Targeting microbubble | Glioblastoma multiforme (GBM) | Antiangiogenic therapy | Blood-brain barrier (BBB) | MOUSE-BRAIN | CELLS | MATERIALS SCIENCE, BIOMATERIALS | GENE DELIVERY | GLIOBLASTOMA-MULTIFORME | ENGINEERING, BIOMEDICAL | TUMOR ANGIOGENESIS | BLOOD-BRAIN-BARRIER | CONTRAST AGENT | DISRUPTION | THERAPY | ENDOTHELIAL GROWTH-FACTOR | Ethidium - metabolism | Antineoplastic Agents - therapeutic use | Brain Neoplasms - blood supply | Drug Delivery Systems | Brain - metabolism | Angiogenesis Inhibitors - administration & dosage | Carmustine - therapeutic use | Glioma - therapy | Angiogenesis Inhibitors - therapeutic use | Microbubbles | Antineoplastic Agents - pharmacology | Vascular Endothelial Growth Factor A - pharmacology | Carmustine - adverse effects | Cell Survival - drug effects | Liver - metabolism | Vascular Endothelial Growth Factor A - therapeutic use | Angiogenesis Inhibitors - pharmacology | Rats | Treatment Outcome | Carmustine - pharmacology | Brain Neoplasms - drug therapy | Blood-Brain Barrier - drug effects | Rats, Sprague-Dawley | Ultrasonics | Glioma - blood supply | Blood-Brain Barrier - pathology | Magnetic Resonance Imaging | Animals | Contrast Media | Tumor Burden - drug effects | Brain Neoplasms - therapy | Fluorescent Antibody Technique | Survival Analysis | Brain - pathology | Cell Line, Tumor | Toxicity Tests | Glioma - drug therapy | Microscopy, Fluorescence | Carmustine - administration & dosage | Drugs | Drug delivery systems | Biological products | Gliomas | Brain tumors | Development and progression | Drug therapy | Vehicles | Cancer | Index Medicus | Brain | Biomedical materials | Blood-brain barrier | Toxicity | Biocompatibility | Strategy | Ultrasound | Tumors
Journal Article
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2010, Volume 107, Issue 34, pp. 15205 - 15210
The superparamagnetic properties of magnetic nanoparticles (MNPs) allow them to be guided by an externally positioned magnet and also provide contrast for MRI.... 
Nanoparticles | Brain | Medical treatment | Imaging | Central nervous system | Brain neoplasms | Magnetic fields | Blood brain barrier | Magnets | Tumors | Magnetic targeting | Focused ultrasound | Blood-brain barrier | Magnetic nanoparticles | Brain drug delivery | blood-brain barrier | GLIOMAS | magnetic targeting | PERMEABILITY | DRUG-DELIVERY | MULTIDISCIPLINARY SCIENCES | MOUSE | TUMOR | brain drug delivery | magnetic nanoparticles | CHEMOTHERAPY | BARRIER DISRUPTION | ISSUES | CENTRAL-NERVOUS-SYSTEM | TECHNOLOGY | focused ultrasound | Microscopy, Electron, Transmission | Metal Nanoparticles - therapeutic use | Rats | Brain Neoplasms - blood supply | Epirubicin - administration & dosage | Brain Neoplasms - drug therapy | Magnetics | Rats, Sprague-Dawley | Antibiotics, Antineoplastic - administration & dosage | Magnetic Resonance Imaging | Animals | Contrast Media | Metal Nanoparticles - administration & dosage | Antibiotics, Antineoplastic - therapeutic use | Ultrasonic Therapy | Epirubicin - therapeutic use | Brain Neoplasms - ultrastructure | Drug Delivery Systems - methods | Blood-Brain Barrier | Metal Nanoparticles - ultrastructure | Drugs | Drug delivery systems | Magnetic resonance imaging | Ultrasonics in medicine | Dosage and administration | Research | Properties | Methods | Central nervous system agents | Vehicles | Pathology | Magnetism | Nuclear magnetic resonance--NMR | Index Medicus | N.M.R | Chemotherapy | nanoparticles | Macromolecules | Ultrasound | Biological Sciences | blood–brain barrier
Journal Article
Journal of neurosurgery, ISSN 0022-3085, 01/2019, pp. 1 - 12
OBJECTIVEDespite intensive medical treatment, patients with glioblastoma (grade IV glioma [GBM]) have a low 5-year survival rate of 5.5%. In this study, the... 
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e58995 - e58995
The purpose of this study is to assess the preclinical therapeutic efficacy of magnetic resonance imaging (MRI)-monitored focused ultrasound (FUS)-induced... 
ANTITUMOR AGENT TEMOZOLOMIDE | RECURRENT MALIGNANT GLIOMA | DISRUPTION | HUMAN PLASMA | RAT | PERMEABILITY | MULTIDISCIPLINARY SCIENCES | DOXORUBICIN | TUMOR | CHEMOTHERAPY | ADJUVANT TEMOZOLOMIDE | Glioblastoma - diagnosis | Dacarbazine - therapeutic use | Brain Neoplasms - diagnosis | Rats | Male | Antineoplastic Agents, Alkylating - pharmacokinetics | Sound | Brain Neoplasms - drug therapy | Blood-Brain Barrier - metabolism | Antineoplastic Agents, Alkylating - therapeutic use | Magnetic Resonance Imaging | Animals | Dacarbazine - analogs & derivatives | Blood-Brain Barrier - radiation effects | Brain - pathology | Cell Line, Tumor | Dacarbazine - pharmacokinetics | Brain Neoplasms - mortality | Drug Evaluation, Preclinical | Glioblastoma - drug therapy | Glioblastoma - mortality | Disease Models, Animal | Brain | Development and progression | Temozolomide | Health aspects | Glioblastoma multiforme | Brain tumors | Neuroimaging | Nuclear magnetic resonance--NMR | Dyes | Brain cancer | Glioblastoma | Parenchyma | Clinical trials | Cerebrospinal fluid | Neurosurgery | Cancer therapies | Molecular weight | FUS protein | Ultrasonic imaging | Blood-brain barrier | Glioma cells | Animal tissues | Ultrasound | Electrical engineering | Medical imaging | Histology | Permeability | Survival | Chemotherapy | Brain research | Magnetic resonance imaging | Spectrophotometry | Tumors | Index Medicus | Nuclear magnetic resonance | NMR
Journal Article