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Advances in experimental medicine and biology, ISSN 0065-2598, 2019, Volume 1210, p. 319
The PI3K signaling pathway is activated in a majority of cancer types. It promotes tumorigenesis by regulating nutrient metabolism, cell proliferation,... 
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 12/2015, Volume 14, Issue 12 Supplement 2, pp. LB-A25 - LB-A25
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 01/2018, Volume 28, Issue 2, pp. 141 - 163
Aims: Microglia-mediated neuroinflammation plays an important role in focal ischemic stroke, a disorder with no effective therapeutic agents. Since microglial... 
Original Research Communications | AMPK | neuroinflammation | Nrf2 | stroke | microglia polarization | OXIDATIVE STRESS | PROTEIN-KINASE | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOCAL CEREBRAL-ISCHEMIA | RECEPTOR BLOCKERS | PERITONEAL-MACROPHAGES | MICROGLIA/MACROPHAGE POLARIZATION | SIGNALING PATHWAY | ANTIOXIDANT DEFENSE | ENDOCRINOLOGY & METABOLISM | NF-KAPPA-B | Microglia - metabolism | AMP-Activated Protein Kinases - metabolism | Brain Ischemia | Stroke - complications | NF-E2-Related Factor 2 - agonists | PPAR gamma - metabolism | Antioxidants | Microglia - immunology | Neuroprotective Agents - pharmacology | Encephalitis - metabolism | Microglia - pathology | Female | Neurons - metabolism | Neurons - drug effects | Macrophages - immunology | Disease Models, Animal | Neuroprotective Agents - chemistry | alpha-Defensins - chemistry | Rats | Encephalitis - immunology | Macrophage Activation | alpha-Defensins - pharmacology | Macrophages - metabolism | Animals | Cerebral Infarction | NF-E2-Related Factor 2 - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Kinase - metabolism | Macrophages - drug effects | Mice | Encephalitis - etiology | Brain | Care and treatment | Inflammation | Research | Health aspects | Protein kinases | Benzoic acid | Neuroprotection | Polarization | Oxidative stress | Stroke | Hybrids | AMP | Toxicity | Innovations | Pyruvic acid | Radioactive half-life | Activation | Pharmacology | Kinases | Neuroprotective agents | AMP-activated protein kinase | Chemical compounds | Microglia | Neurological diseases | Ischemia | Rodents | Index Medicus
Journal Article
亚洲男性学杂志:英文版, ISSN 1008-682X, 2013, Issue 6, pp. 703 - 704
The androgen receptor (AR) is a pleio-trophic transcription factor that regu-lates expression of a large number of genes involved in many diverse cellular... 
前列腺癌 | 抑制剂 | OT | 转录因子 | 基因抑制 | 雄激素受体 | 骨架 | 附着
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 1805 - 1805
Journal Article
Nature Communications, ISSN 2041-1723, 05/2014, Volume 5, Issue 1, p. 3930
Journal Article
Applied Surface Science, ISSN 0169-4332, 11/2019, Volume 494, p. 430
Monodisperse Cu nanoparticles @ MoS.sub.2 nanosheets were prepared via a facile in-situ reduction method. The anchored Cu nanoparticles with average diameters... 
Nanoparticles | Lubrication and lubricants | X-ray spectroscopy | Tribology
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 2011, Volume 1813, Issue 11, pp. 1961 - 1964
Journal Article
Cancer Research, ISSN 0008-5472, 08/2017, Volume 77, Issue 16, pp. 4328 - 4341
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2017, Volume 23, Issue 9, pp. 1055 - 1062
Bromodomain and extraterminal domain (BET) protein inhibitors are emerging as promising anticancer therapies. The gene encoding the E3 ubiquitin ligase... 
SELECTIVE-INHIBITION | TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | ANDROGEN RECEPTOR | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACUTE MYELOID-LEUKEMIA | ENHANCERS | CELL BIOLOGY | RNA-SEQ | BROMODOMAIN INHIBITION | MUTATIONS | BRD4 | Prostatic Neoplasms - metabolism | Immunoprecipitation | TOR Serine-Threonine Kinases - metabolism | Humans | Drug Resistance, Neoplasm | Male | Gene Expression Profiling | Molecular Targeted Therapy | Mechanistic Target of Rapamycin Complex 1 | Transcription Factors - drug effects | Multiprotein Complexes - metabolism | Prostatic Neoplasms - genetics | Proteasome Endopeptidase Complex - drug effects | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Nuclear Proteins - drug effects | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | TOR Serine-Threonine Kinases - drug effects | Multiprotein Complexes - drug effects | Prostatic Neoplasms - drug therapy | Protein-Serine-Threonine Kinases - metabolism | Repressor Proteins - metabolism | RNA-Binding Proteins - antagonists & inhibitors | Triazoles - therapeutic use | Cell Survival | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Azepines - therapeutic use | RNA-Binding Proteins - drug effects | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Nuclear Proteins - antagonists & inhibitors | Protein-Serine-Threonine Kinases - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Mutation | RNA-Binding Proteins - metabolism | rac1 GTP-Binding Protein - metabolism | Proto-Oncogene Proteins c-akt - drug effects | rac1 GTP-Binding Protein - genetics | Gene mutations | Physiological aspects | Genetic aspects | Research | Drug resistance | Drug therapy | Prostate cancer | Ubiquitin | Inhibitor drugs | Stabilization | AKT protein | Activation | Biosynthesis | Degradation | Proteins | Ubiquitination | Transcription activation | Ubiquitin-protein ligase | Binding | Rac1 protein | Tumor cell lines | Gene expression | Cholesterol | Mutants | Inhibitors | Proteasomes | Biomarkers | Bet protein | Prostate | Cancer | Guanosinetriphosphatase
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 04/2017, Volume 36, Issue 8, pp. 995 - 1010
Journal Article
Sensors (Basel, Switzerland), ISSN 1424-8220, 11/2019, Volume 19, Issue 22, p. 5000
The detection of defects on irregular surfaces with specular reflection characteristics is an important part of the production process of sanitary equipment.... 
SYSTEM | CHEMISTRY, ANALYTICAL | INSTRUMENTS & INSTRUMENTATION | defect detection | feature fusion | VISION | K-Means | CLASSIFICATION | irregular surfaces | ENGINEERING, ELECTRICAL & ELECTRONIC | k-means
Journal Article
Journal of Food Science, ISSN 0022-1147, 10/2018, Volume 83, Issue 10, pp. 2662 - 2668
Journal Article
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