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Journal Article
by Heerspink, Hiddo J L and Parving, Hans-Henrik and Andress, Dennis L and Bakris, George and Correa-Rotter, Ricardo and Hou, Fan-Fan and Hou, Fanfan and Kitzman, Dalane W and Kohan, Donald and Makino, Shinya and Makino, Hirofumi and McMurray, John J V and Melnick, Joel Z and Miller, Michael G and Miller, Alan and Miller, Steven and Pergola, Pablo E and Pergola, Pablo and Perkovic, Vlado and Tobe, Sheldon and Yi, Joo Hark and Yi, Tingting and Wigderson, Melissa and de Zeeuw, Dick and Elbert, Alicia and Vallejos, Augusto and Alvarisqueta, Andres and Maffei, Laura and Juncos, Luis and de Arteaga, Javier and Greloni, Gustavo and Farias, Eduardo and Zucchini, Alfredo and Vogel, Daniel and Cusumano, Ana and Santos, Juan and Fraenkel, Margaret and Gallagher, Martin and Davis, Tim and Acharya, Shamasunder and Cooke, Duncan and Suranyi, Michael and Roger, Simon and Toussaint, Nigel and Pollock, Carol and Chan, Doris and Stranks, Stephen and MacIsaac, Richard and Endre, Zoltan and Schmidt, Alice and Schmidt, Rebecca and Prager, Rudolf and Mayer, Gert and Warling, Xavier and Jadoul, Michel and Hougardy, Jean and Vercammen, Chris and Van Vlem, Bruno and Gillard, Pieter and Costa e Forti, Adriana and Borges, Joao Lindolfo and Santos Canani, Luis and Eliaschewitz, Freddy and Leite, Silmara and Fraige Filho, Fadlo and Paschoalin, Raphael and Moura Neto, Jose Andrade and Deboni, Luciane and de Lourdes Noronha, Irene and Cercato, Cintia and Prompt, Carlos Alberto and Zanella, Maria and Rassi, Nelson and D'Avila, Domingos and Milagres, Rosangela and Felicio, Joao and Pecoits Filho, Roberto and Riella, Miguel Carlos and Salles, Joao and Keitel, Elizete and Draibe, Sergio and Amodeo, Celso and Youmbissi, Joseph and Roy, Louise and Cournoyer, Serge and Jolly, Shivinder and Pichette, Vincent and Nesrallah, Gihad and Bajaj, Harpreet Singh and Khandwala, Hasnain and Aronson, Ronnie and Goluch, Richard and Tam, Paul and Rabbat, Christian and Bailey, Gordon and Chow, Stephen and Castillo, Alvaro and Danin Vargas, Alfredo and Gonzalez, Fernando and Munoz, Rodrigo and ... and SONAR Comm Investigators and SONAR Committees and Investigators
The Lancet, ISSN 0140-6736, 05/2019, Volume 393, Issue 10184, pp. 1937 - 1947
Short-term treatment for people with type 2 diabetes using a low dose of the selective endothelin A receptor antagonist atrasentan reduces albuminuria without... 
MEDICINE, GENERAL & INTERNAL | INHIBITION | ENDOTHELIN | ALBUMINURIA | NEPHROPATHY | Humans | Middle Aged | Male | Diabetic Nephropathies - blood | Serum Albumin, Human - urine | Young Adult | Aged, 80 and over | Adult | Female | Diabetic Nephropathies - prevention & control | Endothelin A Receptor Antagonists - therapeutic use | Diabetic Nephropathies - urine | Glomerular Filtration Rate | Double-Blind Method | Endothelin A Receptor Antagonists - administration & dosage | Administration, Oral | Treatment Outcome | Creatinine - urine | Renal Insufficiency, Chronic - blood | Renal Insufficiency, Chronic - prevention & control | Atrasentan - therapeutic use | Creatinine - blood | Aged | Atrasentan - administration & dosage | Diabetes Mellitus, Type 2 - drug therapy | Renal Insufficiency, Chronic - urine | Short term | Enrichment | End-stage renal disease | Renal function | Endothelin | Heart attacks | Peptides | Clinical trials | Cardiovascular disease | Transplantation | Retention | Randomization | Renin | Motivation | Hemoglobin | Blood pressure | Safety | Diabetes mellitus (non-insulin dependent) | Heart diseases | Drug dosages | Heart failure | Urine | Creatinine | Enzymes | Kidneys | Epidermal growth factor receptors | Anemia | Diabetes mellitus | Health risks | Patients | Disease control | Glomerular filtration rate | Sodium | Angiotensin | Renal failure | Dialysis | Kidney diseases | Diabetes | Surface area | Potassium | Kidney transplantation | Long-term effects
Journal Article
Journal of Endocrinology, ISSN 0022-0795, 2016, Volume 231, Issue 2, pp. 109 - 120
Obesity is a risk factor that promotes progressive kidney disease. Studies have shown that an adipocytokine imbalance contributes to impaired renal function in... 
Adipocytokine | Visceral fat | Podocytopathy | Adipocytes | High-fat diet | adipocytokine | METABOLIC SYNDROME | ALBUMINURIA | ABDOMINAL OBESITY | OBESITY-RELATED GLOMERULOPATHY | ADIPONECTIN | INSULIN-RESISTANCE | high-fat diet | IMAGE-ANALYSIS | ENDOCRINOLOGY & METABOLISM | podocytopathy | HEMODIALYSIS-PATIENTS | CHRONIC KIDNEY-DISEASE | adipocytes | visceral fat | CARDIOVASCULAR RISK-FACTORS | Biomarkers - urine | Kidney Cortex - metabolism | Renal Insufficiency, Chronic - diagnostic imaging | Diet, High-Fat - adverse effects | Kidney Cortex - physiopathology | Male | Intra-Abdominal Fat - secretion | Renal Insufficiency, Chronic - metabolism | Adiposity | Obesity - etiology | Disease Models, Animal | Biomarkers - metabolism | Cell Line | Microscopy, Electron, Transmission | Kidney Cortex - ultrastructure | Podocytes - metabolism | Gene Expression Regulation | Insulin Resistance | Organ Size | Kidney Cortex - pathology | Obesity - physiopathology | Adipocytes, White - secretion | Biomarkers - blood | Podocytes - pathology | 3T3-L1 Cells | Intra-Abdominal Fat - metabolism | Rats, Sprague-Dawley | Renal Insufficiency, Chronic - physiopathology | Disease Progression | Renal Insufficiency, Chronic - pathology | Culture Media, Conditioned | Podocytes - ultrastructure | Adipocytes, White - pathology | Animals | Mice | Intra-Abdominal Fat - pathology | Adipocytes, White - metabolism
Journal Article
Endocrinology, ISSN 0013-7227, 01/2011, Volume 152, Issue 2, pp. 384 - 393
Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme catabolism, has antioxidant, antiinflammatory, and antiapoptotic effects in many physiological... 
1-Phosphatidylinositol 3-kinase
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 06/2013, Volume 709, Issue 1-3, pp. 85 - 92
The mechanisms underlying insulin sensitivity and fat tissue distribution in chronic renal insufficiency remain unclear. Previous studies have shown the... 
Visceral fat | Adipocytokine | Chronic kidney disease | Angiotensin II receptor blocker | Insulin sensitivity | METABOLIC SYNDROME | DIABETIC-NEPHROPATHY | ATHEROSCLEROSIS MIA SYNDROME | ADIPONECTIN LEVELS | NUTRITIONAL-STATUS | REDUCED GENE-EXPRESSION | INSULIN-RESISTANCE | HEMODIALYSIS-PATIENTS | CARDIOVASCULAR MORTALITY | PHARMACOLOGY & PHARMACY | CHRONIC KIDNEY-DISEASE | Kidney - pathology | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Kidney - immunology | Male | Protective Agents - therapeutic use | Hypertension - etiology | Renal Insufficiency, Chronic - drug therapy | Renal Insufficiency, Chronic - metabolism | Adipokines - genetics | Hypertension - prevention & control | Intra-Abdominal Fat - drug effects | Kidney - physiopathology | Disease Models, Animal | Intra-Abdominal Fat - immunology | Adiposity - drug effects | Kidney - drug effects | Cell Size - drug effects | Cells, Cultured | Insulin Resistance | Rats | Adipokines - metabolism | Antihypertensive Agents - therapeutic use | Intra-Abdominal Fat - metabolism | Rats, Sprague-Dawley | Renal Insufficiency, Chronic - physiopathology | Adipokines - antagonists & inhibitors | Renal Insufficiency, Chronic - pathology | Gene Expression Regulation - drug effects | Animals | Nephrectomy - adverse effects | Losartan - therapeutic use | Intra-Abdominal Fat - pathology | Hypertension
Journal Article
Taiwanese Journal of Obstetrics & Gynecology, ISSN 1028-4559, 10/2018, Volume 57, Issue 5, pp. 696 - 704
Hyperandrogenism is the hallmark of polycystic ovary syndrome (PCOS). The use of dehydroepiandrosterone (DHEA)-treated rats is thought to be a suitable animal... 
DHEA | Polycystic ovary syndrome | Insulin sensitivity | CELLS | PRASTERONE | INSULIN-RESISTANCE | DYSFUNCTION | SECRETION | GLUCOSE-UPTAKE | EXPRESSION | OBSTETRICS & GYNECOLOGY | Complications and side effects | Metabolic diseases | Models | Research | Stein-Leventhal syndrome | Risk factors
Journal Article
Terrestrial, Atmospheric and Oceanic Sciences, ISSN 1017-0839, 12/2011, Volume 22, Issue 6, pp. 613 - 632
Journal Article
Biology of Reproduction, ISSN 0006-3363, 07/2007, Volume 77, Issue Suppl_1, pp. 136 - 137
Journal Article
Endocrinology, ISSN 0013-7227, 04/2007, Volume 148, Issue 4, pp. 1835 - 1842
Adiponectin, which is specifically and highly expressed in adipose tissue, has pleiotropic insulin-sensitizing effects. Endothelin-1 (ET-1) is a potent... 
Journal Article
The Chinese journal of physiology, ISSN 0304-4920, 06/2012, Volume 55, Issue 3, pp. 178 - 183
"We undertook this study to investigate the adequate oxygen concentration that can be applied safely to the treatment of pneumothorax. Complete unilateral... 
Rabbits | Pneumothorax | Animals | Lung | Interleukin-1beta | Interleukin-8 | Oxygen - blood
Journal Article
American Journal of Physiology, ISSN 0193-1849, 03/2008, Volume 294, Issue 3, p. E481
¬† Leptin, one of the adipocyte-secreted peptides, is involved in the control of appetite and body weight. Several studies have demonstrated that plasma leptin... 
Proteins | Peptides | Endocrine system | Hormones | Muscular system | Cells | Weight
Journal Article
American Journal of Physiology: Endocrinology and Metabolism, ISSN 0193-1849, 03/2008, Volume 294, Issue 3, pp. E481 - E487
Leptin, one of the adipocyte-secreted peptides, is involved in the control of appetite and body weight. Several studies have demonstrated that plasma leptin... 
Journal Article
Journal Article