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Clinical and Translational Science, ISSN 1752-8054, 12/2008, Volume 1, Issue 3, pp. 187 - 187
The Food and Drug Administration's (FDA's) Critical Path Initiative is a broad effort to update and streamline the development, production, and evaluation of... 
MEDICINE, RESEARCH & EXPERIMENTAL | Industry | United States | Critical Pathways | Humans | United States Food and Drug Administration | Precision Medicine | Index Medicus
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 07/2019, Volume 106, Issue 1, pp. 10 - 18
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 01/2019, Volume 108, Issue 1, pp. 18 - 20
Model-based analyses have been applied to influence various drug development and regulatory decisions in the last 2 decades. Applied models range from... 
pharmacokinetic/pharmacodynamic (PK/PD) modeling | regulatory science | physiologically based pharmacokinetic (PBPK) modeling | clinical trial simulation(s) | ADME | computational | CHEMISTRY, MEDICINAL | PHARMACOLOGY & PHARMACY | SCIENCE | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
2006, Drugs and the Pharmaceutical Sciences, ISBN 9780824725389, Volume 162., xiii, 332
The international popularity of herbal remedies has recently outpaced quality information on the utilization and dosing of these compounds. This book fills a... 
Drug-herb interactions | Consumer protection -- Law and legislation | Herbs -- Therapeutic use -- Side effects | Medicine, Herbal - legislation & jurisprudence | Herbs | Consumer protection
Book
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 07/2019, Volume 106, Issue 1, pp. 67 - 71
Real-world data (RWD; e.g., data from healthcare records, claims databases, and registries) have been used to generate real-world evidence (RWE) and to provide... 
PHARMACOLOGY & PHARMACY
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 11/2018, Volume 104, Issue 5, pp. 766 - 771
The past few years have ushered in a wealth of new information on transporter biology, ranging from the publication of new crystal structures of the human... 
PHARMACOLOGY & PHARMACY | Index Medicus | Abridged Index Medicus
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 03/2014, Volume 42, Issue 3, pp. 318 - 322
Journal Article
Clinical Pharmacology and Therapeutics, ISSN 0009-9236, 2018, Volume 105, Issue 5, pp. 1067 - 1070
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 04/2019, Volume 105, Issue 4, pp. 899 - 911
Model‐informed drug development (MIDD) refers to the application of a wide range of quantitative models in drug development to facilitate the decision‐making... 
FDA | THOROUGH QT | PHARMACOLOGY | DISEASE | EDITOR STATISTICAL ISSUES | PHARMACOLOGY & PHARMACY | SCIENCE | OPPORTUNITIES
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 07/2019, Volume 106, Issue 1, pp. 91 - 93
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. 2569 - 2569
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 03/2010, Volume 9, Issue 3, pp. 175 - 176
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 11/2018, Volume 104, Issue 5, pp. 793 - 796
Transporters can affect a drug's pharmacokinetics (PK) by controlling absorption, distribution, and elimination processes. They can also affect a drug's... 
PHARMACOLOGY & PHARMACY | IN-VITRO | DABIGATRAN | VIVO | P-GLYCOPROTEIN | Index Medicus | Abridged Index Medicus
Journal Article
Clinical Pharmacology and Therapeutics, ISSN 0009-9236, 2002, Volume 71, Issue 6, pp. 414 - 420
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 01/2019, Volume 108, Issue 1, pp. 21 - 25
This commentary provides an update on the status of physiologically based pharmacokinetic modeling and simulation at the U.S. Food and Drug Administration's... 
clinical pharmacokinetics | drug-drug interaction(s) | in silico modeling | regulatory science | physiologically based pharmacokinetic (PBPK) modeling | CHEMISTRY, MEDICINAL | SUBMISSIONS | MEMBRANE | PBPK | INDUCTION | SIMULATION | RENAL IMPAIRMENT | CHEMISTRY, MULTIDISCIPLINARY | PREDICTION | EFFLUX TRANSPORTERS | INHIBITION | SUBSTRATE | PHARMACOLOGY & PHARMACY
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 759 - 759
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 09/2019, Volume 59, Issue S1, pp. S56 - S69
Developmental changes in the biological processes involved in the disposition of drugs, such as membrane transporter expression and activity, may alter the... 
model‐informed drug development | transporters | children | physiologically based pharmacokinetic modeling | PBPK | ontogeny | pediatric | Pediatrics | Developmental biology | Ontogeny | Exposure | Pharmacology | Drug development | Biological activity | Prescription drugs | Developmental stages | Intestine | Predictions | Collaborative work | Modelling | Children | Transporter | Index Medicus
Journal Article
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