X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (327) 327
Patent (140) 140
Dissertation (31) 31
Magazine Article (28) 28
Conference Proceeding (14) 14
Publication (14) 14
Book / eBook (1) 1
Book Review (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (50) 50
chemistry (44) 44
metallurgy (43) 43
physics (41) 41
human necessities (39) 39
humans (33) 33
animals (30) 30
performing operations (25) 25
transporting (25) 25
measuring (22) 22
testing (22) 22
mice (20) 20
microbiology (20) 20
hygiene (18) 18
medical or veterinary science (18) 18
biochemistry (17) 17
cell biology (17) 17
foods or foodstuffs (17) 17
their treatment, not covered by other classes (17) 17
wine (17) 17
beer (16) 16
compositions based thereon (16) 16
enzymology (16) 16
female (16) 16
foods, foodstuffs, or non-alcoholic beverages, not covered bysubclasses a23b - a23j (16) 16
investigating or analysing materials by determining theirchemical or physical properties (16) 16
mutation or genetic engineering (16) 16
organic macromolecular compounds (16) 16
preservation of foods or foodstuffs, in general (16) 16
spirits (16) 16
their preparation or chemical working-up (16) 16
their preparation or treatment, e.g. cooking, modification ofnutritive qualities, physical treatment (16) 16
vinegar (16) 16
cancer (15) 15
male (15) 15
calculating (14) 14
computing (14) 14
counting (14) 14
compositions or test papers therefor (13) 13
condition-responsive control in microbiological orenzymological processes (13) 13
measuring or testing processes involving enzymes, nucleicacids or microorganisms (13) 13
processes of preparing such compositions (13) 13
conveying (12) 12
electricity (12) 12
handling thin or filamentary material (12) 12
packing (12) 12
polysaccharides (12) 12
signal transduction (12) 12
storing (12) 12
cell line, tumor (11) 11
derivatives thereof (11) 11
mutation (11) 11
genes (9) 9
genetic aspects (9) 9
kinases (9) 9
chemical aspects of bandages, dressings, absorbent pads, orsurgical articles (8) 8
disinfection, sterilisation, or deodorisation of air (8) 8
expression (8) 8
genetics & heredity (8) 8
materials for bandages, dressings, absorbent pads, or surgicalarticles (8) 8
materials science, multidisciplinary (8) 8
methods or apparatus for sterilising materials or objects ingeneral (8) 8
research (8) 8
studies (8) 8
tumors (8) 8
四轮驱动 (8) 8
accessories, closures, or fittings therefor (7) 7
aged (7) 7
analysis (7) 7
biochemistry & molecular biology (7) 7
containers for storage or transport of articles or materials,e.g. bags, barrels, bottles, boxes, cans, cartons, crates,drums, jars, tanks, hoppers, forwarding containers (7) 7
differentiation (7) 7
electric communication technique (7) 7
electric digital data processing (7) 7
molecular sequence data (7) 7
multidisciplinary sciences (7) 7
neurosciences (7) 7
oncology (7) 7
packages (7) 7
packaging elements (7) 7
preparations for medical, dental, or toilet purposes (7) 7
proteins (7) 7
transmission of digital information, e.g. telegraphiccommunication (7) 7
article (6) 6
fixed constructions (6) 6
mice, inbred c57bl (6) 6
middle aged (6) 6
phosphorylation (6) 6
activation (5) 5
amino acid sequence (5) 5
chemistry, multidisciplinary (5) 5
compositions of macromolecular compounds (5) 5
data processing systems or methods, specially adapted foradministrative, commercial, financial, managerial, supervisoryor forecasting purposes (5) 5
diagnosis (5) 5
general tagging of cross-sectional technologies spanning over several sections of the ipc (5) 5
general tagging of new technological developments (5) 5
genomics (5) 5
melanoma (5) 5
mri (5) 5
neuroimaging (5) 5
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature, ISSN 0028-0836, 03/2012, Volume 483, Issue 7387, pp. 100 - 104
Inhibition of the BRAF(V600E) oncoprotein by the small-molecule drug PLX4032 (vemurafenib) is highly effective in the treatment of melanoma(1). However, colon... 
PANITUMUMAB | TARGET | CETUXIMAB | MELANOMA | BRAF MUTATIONS | MULTIDISCIPLINARY SCIENCES | PAPILLARY THYROID-CARCINOMA | KRAS | METASTATIC COLORECTAL-CANCER | Erlotinib Hydrochloride | Receptor, Epidermal Growth Factor - agonists | Apoptosis - drug effects | Colorectal Neoplasms - genetics | Humans | Antineoplastic Agents - therapeutic use | Antibodies, Monoclonal, Humanized | Receptor, Epidermal Growth Factor - metabolism | RNA Interference | Colorectal Neoplasms - drug therapy | HEK293 Cells | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Cetuximab | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Melanoma - metabolism | Colorectal Neoplasms - enzymology | Antibodies, Monoclonal - pharmacology | Enzyme Activation - drug effects | Sulfonamides - pharmacology | Drug Synergism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Sulfonamides - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Quinazolines - therapeutic use | Melanoma - drug therapy | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Feedback, Physiological - drug effects | Indoles - therapeutic use | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Colorectal Neoplasms - pathology | Quinazolines - pharmacology | Drug Resistance, Neoplasm - drug effects | Proteins | Library collections | Studies | Phosphorylation | Kinases | Tumors | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 1, pp. 118 - 122
Treatment of BRAF(V600E) mutant melanoma by small molecule drugs that target the BRAF or MEK kinases can be effective, but resistance develops invariably(1,2).... 
GROWTH-FACTOR RECEPTOR | BRAF INHIBITOR | RAF INHIBITION | CELLS | MULTIDISCIPLINARY SCIENCES | IMPROVED SURVIVAL | DIFFERENTIATION | C-JUN | CANCER | EXPRESSION | EGFR | Receptor, Epidermal Growth Factor - genetics | Humans | Receptor Protein-Tyrosine Kinases - biosynthesis | Cellular Senescence - drug effects | Melanoma - enzymology | Antineoplastic Agents - administration & dosage | Receptor, Platelet-Derived Growth Factor beta - genetics | Indoles - administration & dosage | Mitogen-Activated Protein Kinase Kinases - metabolism | Receptor, Epidermal Growth Factor - metabolism | Flow Cytometry | Melanoma - genetics | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | SOXE Transcription Factors - deficiency | Proto-Oncogene Proteins B-raf - metabolism | Receptor, Platelet-Derived Growth Factor beta - metabolism | Receptor, Epidermal Growth Factor - biosynthesis | Gene Library | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Melanoma - pathology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Transforming Growth Factor beta - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Signal Transduction - drug effects | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering | Transforming Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor beta - biosynthesis | Sulfonamides - administration & dosage | Drug Resistance, Neoplasm - drug effects | SOXE Transcription Factors - genetics | Proteins | Biopsy | Rodents | Genes | Melanoma | Mutation | Kinases | Drug resistance | Patients | Tumors | Index Medicus
Journal Article
Cell Reports, ISSN 2211-1247, 10/2014, Volume 7, Issue 1, pp. 86 - 93
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2015, Volume 25, Issue 4, pp. 445 - 458
Recurrent inactivating mutations in components of SWI/SNF chromatin-remodeling complexes have been identified across cancer types, supporting their roles as... 
ALK | 抑制剂 | 肿瘤抑制 | 表皮生长因子 | 非小细胞肺癌 | MET | EGFR | SMARCE1 | EGFR signaling | RNAi screening | Drug resistance | SWI/SNF | ACTIVATION | BRAF(V600E) INHIBITION | GERM-LINE | REMODELING GENE ARID1A | SOMATIC MUTATIONS | CELL BIOLOGY | SMALL-CELL CARCINOMA | HYPERCALCEMIC TYPE | RESISTANCE | drug resistance | DIFFERENTIATION | HSNF5/INI1 | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Humans | Lung Neoplasms - pathology | Polycomb Repressive Complex 1 - biosynthesis | Chromosomal Proteins, Non-Histone - biosynthesis | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Quinazolines - administration & dosage | Gene Expression Regulation, Neoplastic - drug effects | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Receptor, Epidermal Growth Factor - biosynthesis | Carcinoma, Non-Small-Cell Lung - genetics | Proto-Oncogene Proteins c-met - antagonists & inhibitors | DNA-Binding Proteins - genetics | Chromosomal Proteins, Non-Histone - genetics | Proto-Oncogene Proteins c-met - genetics | Drug Resistance, Neoplasm - genetics | Receptor Protein-Tyrosine Kinases - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | DNA-Binding Proteins - biosynthesis | Drug Resistance, Neoplasm - drug effects | Index Medicus | SWI | SNF | Original
Journal Article
Journal of Pharmacological Sciences, ISSN 1347-8613, 09/2016, Volume 132, Issue 1, pp. 15 - 23
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, pp. e75139 - e75139
Resveratrol, a natural polyphenol compound, has broad effects on critical events, including inflammation, oxidation, cancer and aging. However, the function... 
EXPLANATION | WINE | DEACETYLATION | ACETYLATION | MULTIDISCIPLINARY SCIENCES | MICE | MECHANISMS | SACCHAROMYCES-CEREVISIAE | FRENCH PARADOX | PROTECTS | P53 | Sirtuin 1 - metabolism | Arthritis, Experimental - drug therapy | Immunoprecipitation | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Stilbenes - pharmacology | CD4-Positive T-Lymphocytes - pathology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Arthritis, Experimental - metabolism | Cell Nucleus - metabolism | Arthritis, Experimental - chemically induced | Collagen - toxicity | Mice, Inbred DBA | Enzyme-Linked Immunosorbent Assay | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Blotting, Western | Mice, Knockout | Gene Expression Regulation - drug effects | Acetylation - drug effects | Animals | Lymphocyte Activation - drug effects | Cell Proliferation - drug effects | Mice | CD4-Positive T-Lymphocytes - drug effects | Transcription factors | Cardiovascular disease | Activation | Lymphocytes T | Biology | Arthritis | Kinases | Signal transduction | Cell activation | Cell growth | Lymphocytes | Rodents | Resveratrol | Aging | Oxidation | Acetylation | Translocation | Medical research | Immunoglobulins | c-Jun protein | T cell receptors | SIRT1 protein | CD4 antigen | Studies | Molecular modelling | Collagen | Aging (natural) | Laboratory animals | Cancer | Index Medicus
Journal Article
Antonie van Leeuwenhoek, ISSN 0003-6072, 6/2019, Volume 112, Issue 6, pp. 927 - 933
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 42, pp. 15155 - 15160
Journal Article
Applied and Environmental Microbiology, ISSN 0099-2240, 2016, Volume 82, Issue 13, pp. 3892 - 3899
Journal Article