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Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7576, pp. 100 - 104
Journal Article
Cancer Research, ISSN 0008-5472, 08/2011, Volume 71, Issue 15, pp. 5182 - 5193
Both betulinic acid (BA) and mithramycin A (MIT) exhibit potent antitumor activity through distinct mechanisms of Sp1 inhibition. However, it is unknown... 
TRANSCRIPTION FACTORS | FACTOR FAMILY | IN-VITRO | ONCOLOGY | DUCTAL ADENOCARCINOMA | FACTOR EXPRESSION | CURATIVE RESECTION | VASCULAR-PERMEABILITY FACTOR | IMPROVES SURVIVAL | CELL-LINES | ENDOTHELIAL GROWTH-FACTOR | Adenocarcinoma - pathology | Triterpenes - pharmacology | Humans | Pancreatic Neoplasms - blood supply | Cell Line, Tumor - drug effects | Gene Expression Profiling | Vascular Endothelial Growth Factor A - genetics | Promoter Regions, Genetic - genetics | Pancreatic Neoplasms - drug therapy | Laminin | Plicamycin - administration & dosage | Female | Adenocarcinoma - genetics | Gene Expression Regulation, Neoplastic - drug effects | Recombinant Fusion Proteins - biosynthesis | Proteoglycans | Neoplasm Invasiveness | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Plicamycin - pharmacology | Adenocarcinoma - drug therapy | Cell Division - drug effects | Adenocarcinoma - blood supply | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Sp1 Transcription Factor - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Neovascularization, Pathologic - drug therapy | Collagen | Mice | Mice, Inbred BALB C | Triterpenes - administration & dosage | Drug Combinations | Drug Screening Assays, Antitumor | Index Medicus | mithramycin A | betulinic acid | Sp1 | angiogenesis | VEGF
Journal Article
Nanchang Daxue Xuebao-Gongke Ban = Journal of Nanchang University, ISSN 1006-0456, 01/2018, Issue 2
In order to analyze fatigue behavior of notched specimen under the change of geometric structure and its size,fatigue life tests of notched specimens of Q235... 
Fatigue tests | Stress concentration | Fatigue life | Load distribution (forces) | Tensile stress | Stress distribution | Mathematical analysis | Cyclic loads | Surface properties | Killed steels | Materials fatigue | Dimensional changes
Journal Article
Cancer Cell, ISSN 1535-6108, 04/2017, Volume 31, Issue 4, pp. 591 - 606.e6
The dynamic and reversible -methyladenosine (m A) RNA modification installed and erased by -methyltransferases and demethylases regulates gene expression and... 
ALKBH5 | m6A modification | glioblastoma | FOXM1 | A modification | Index Medicus
Journal Article
Genes & Diseases, ISSN 2352-3042, 03/2016, Volume 3, Issue 1, pp. 41 - 47
Many cancers have similar aberrations in various signaling cascades with crucial roles in cellular proliferation, differentiation, and morphogenesis.... 
β-catenin | Tumorigenicity | Glioma stem cell | Wnt | Cell signaling
Journal Article
Current Molecular Medicine, ISSN 1566-5240, 06/2009, Volume 9, Issue 5, pp. 626 - 633
Metastasis is a major cause of morbidity and mortality in patients with cancer. The molecular mechanisms that control metastasis are related to alterations in... 
Angiogenesis | Metastasis | Transcription factor | Invasion | STAT3 | MEDICINE, RESEARCH & EXPERIMENTAL | CONSTITUTIVE ACTIVATION | G-QUARTET OLIGONUCLEOTIDES | DNA-BINDING ACTIVITY | POTENT ANTITUMOR-ACTIVITY | MOLECULAR TARGETS | EPIDERMAL-GROWTH-FACTOR | PROSTATE-CANCER CELLS | ENDOTHELIAL-CELLS | SQUAMOUS-CELL CARCINOMA | SIGNAL TRANSDUCER
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 4996 - 4996
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0173962
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5566 - 5566
Pyruvate kinase M2 (PKM2) is expressed at high levels during embryonic development and tumour progression and is important for cell growth. However, it is not... 
ACTIVATION | INHIBITION | METABOLISM | MULTIDISCIPLINARY SCIENCES | PYRUVATE-KINASE M2 | DEGRADATION | ISOFORM | BETA-CATENIN | PROMOTES | LIGHT-CHAIN PHOSPHORYLATION | GENE-TRANSCRIPTION | Cell Cycle - genetics | Phosphorylation | Proto-Oncogene Proteins p21(ras) | Aurora Kinase B - metabolism | Myosin Light Chains - genetics | Humans | Gene Expression Regulation, Neoplastic | ras Proteins - metabolism | rho-Associated Kinases - antagonists & inhibitors | Receptor, Epidermal Growth Factor - metabolism | RNA Interference | rho-Associated Kinases - metabolism | Cell Transformation, Neoplastic - genetics | Cytokinesis - physiology | Membrane Proteins - metabolism | Cardiac Myosins - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Amides - pharmacology | Proto-Oncogene Proteins - metabolism | Cell Proliferation - genetics | Pyruvate Kinase - metabolism | Membrane Proteins - genetics | Cardiac Myosins - genetics | HCT116 Cells | Carrier Proteins - antagonists & inhibitors | Brain Neoplasms - genetics | Thyroid Hormones - genetics | Carrier Proteins - genetics | Leupeptins - pharmacology | Pyruvate Kinase - antagonists & inhibitors | Animals | Carrier Proteins - metabolism | Membrane Proteins - antagonists & inhibitors | Mitosis - physiology | Mice, Nude | Thyroid Hormones - metabolism | Cell Line, Tumor | Mice | Myosin Light Chains - metabolism | Pyridines - pharmacology | RNA, Small Interfering | Pyruvate Kinase - genetics | Index Medicus
Journal Article
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4475 - 17
Journal Article