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science & technology (50) 50
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1. Full Text Interactions between cancer stem cells and their niche govern metastatic colonization
by Malanchi, Ilaria and Santamaria-Martínez, Albert and Susanto, Evelyn and Peng, Hong and Lehr, Hans-Anton and Delaloye, Jean-Francois and Huelsken, Joerg
Nature (London), ISSN 0028-0836, 01/2012, Volume 481, Issue 7379, pp. 85 - 91
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Medical sciences | Dissemination | Tumor cell | Tumors | Cell Adhesion Molecules - genetics | Mice, Inbred C57BL | Stromal Cells - metabolism | Cell Adhesion Molecules - metabolism | Animals | Lung Neoplasms - secondary | Neoplastic Stem Cells - metabolism | Breast Neoplasms - pathology | Neoplasm Metastasis - pathology | Neoplastic Stem Cells - pathology | Female | Stem Cell Niche - physiology | Mice | Wnt Signaling Pathway | Lung cancer | Stem cells | Cancer cells | Physiological aspects | Metastasis | Research | Properties | Experiments | Breast cancer | Index Medicus
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2. Full Text Wnt/β-Catenin Is Essential for Intestinal Homeostasis and Maintenance of Intestinal Stem Cells
by Tea Fevr and Sylvie Robine and Daniel Louvard and Joerg Huelsken
Molecular and Cellular Biology, ISSN 0270-7306, 11/2007, Volume 27, Issue 21, pp. 7551 - 7559
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Biomarkers - metabolism | Cell Proliferation | Intestinal Mucosa - ultrastructure | Signal Transduction | Down-Regulation | beta Catenin - deficiency | Homeostasis | Intestines - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Wnt Proteins - metabolism | beta Catenin - metabolism | Intestinal Mucosa - cytology | Intestines - ultrastructure | Cell Lineage | Animals | Mice, Mutant Strains | Cell Death | Transcription, Genetic | Cell Differentiation | Mice | Intestines - physiology | Intestines - cytology | Index Medicus
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3. Full Text Metastasis: New insights into organ-specific extravasation and metastatic niches
by Irmisch, Anja and Huelsken, Joerg
Experimental cell research, ISSN 0014-4827, 07/2013, Volume 319, Issue 11, pp. 1604 - 1610
Cancer stem cell | Niche | Metastasis | Extravasation | Colonization | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasm Metastasis | Animals | Neoplasms - pathology | Organ Specificity | Humans | Disease Progression | Stem cells | Medical research | Cellular biology | Pathogenesis | Index Medicus
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4. Full Text The Wnt signalling pathway
by Huelsken, Joerg and Behrens, Juergen
Journal of cell science, ISSN 0021-9533, 11/2002, Volume 115, Issue 21, pp. 3977 - 3978
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Proto-Oncogene Proteins - metabolism | Animals | Humans | Zebrafish Proteins | Eukaryotic Cells - metabolism | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | Wnt Proteins | Calcium Signaling - genetics | Index Medicus
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5. Full Text Requirement for β-Catenin in Anterior-Posterior Axis Formation in Mice
by Joerg Huelsken and Regina Vogel and Volker Brinkmann and Bettina Erdmann and Carmen Birchmeier and Walter Birchmeier
The Journal of cell biology, ISSN 0021-9525, 2/2000, Volume 148, Issue 3, pp. 567 - 578
Ectoderm | Complementary DNA | Cell adhesion | Mesoderm | Embryonic cells | Embryos | Genetic mutation | Endoderm | Cells | Eggs | Anterior visceral endoderm | Wnt/wingless pathway | Plakoglobin | Armadillo | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phenotype | Animals | beta Catenin | Cytoskeletal Proteins - genetics | Ectoderm - ultrastructure | Trans-Activators | Mice | Cytoskeletal Proteins - physiology | Ectoderm - physiology | Embryonic and Fetal Development - physiology | Body Patterning - physiology | Animal reproduction | Cellular biology | Rodents | Lim1 gene | b-catenin | hex gene | plakoglobin | anterior-posterior axis | cerberus-like gene | hesx1 gene | Index Medicus | anterior visceral endoderm | cell adhesion | armadillo | Wnt | wingless pathway | Original
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6. Full Text A Subset of Cancer-Associated Fibroblasts Determines Therapy Resistance
by Huelsken, Joerg and Hanahan, Douglas
Cell (Cambridge), ISSN 0092-8674, 02/2018, Volume 172, Issue 4, pp. 643 - 644
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Fibroblasts | Tumor Microenvironment | Signal Transduction | Carcinogenesis | Humans | Cancer-Associated Fibroblasts | Cancer | Index Medicus
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7. Full Text β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
by Huelsken, Joerg and Vogel, Regina and Erdmann, Bettina and Cotsarelis, George and Birchmeier, Walter
Cell (Cambridge), ISSN 0092-8674, 2001, Volume 105, Issue 4, pp. 533 - 545
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | beta Catenin | Cytoskeletal Proteins - genetics | Trans-Activators | Keratinocytes - cytology | Stem Cells - cytology | Viral Proteins | Stem Cells - metabolism | Cell Lineage - physiology | Mice, Knockout | Gene Expression Regulation, Enzymologic | Hair Follicle - cytology | Keratin-14 | Phenotype | Animals | Keratinocytes - metabolism | Gene Deletion | Cytoskeletal Proteins - metabolism | Mice | Hair Follicle - embryology | Keratins - genetics | Mutagenesis, Insertional - physiology | Cell Differentiation - physiology | Integrases - genetics | Morphogenesis | Cell research | Gene mutations | Analysis | Stem cells | Physiological aspects | Epidermis | Genetic aspects | Hair follicles | b-Catenin | Index Medicus
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8. Full Text HOXA5 Counteracts Stem Cell Traits by Inhibiting Wnt Signaling in Colorectal Cancer
by Ordóñez-Morán, Paloma and Dafflon, Caroline and Imajo, Masamichi and Nishida, Eisuke and Huelsken, Joerg
Cancer cell, ISSN 1535-6108, 12/2015, Volume 28, Issue 6, pp. 815 - 829
β-catenin | cancer stem cells | MYC | retinoids | Retinoids | Cancer stem cells | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Intestinal Mucosa - metabolism | Cell Proliferation | Neoplastic Stem Cells - drug effects | Colorectal Neoplasms - genetics | Homeodomain Proteins - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Phosphoproteins - metabolism | Neoplasm Metastasis | Transfection | Neoplastic Stem Cells - metabolism | RNA Interference | Time Factors | Cell Transformation, Neoplastic - genetics | Colorectal Neoplasms - drug therapy | Aged, 80 and over | Neoplastic Stem Cells - pathology | Female | Antineoplastic Agents - pharmacology | Cell Differentiation | Tumor Cells, Cultured | Colorectal Neoplasms - metabolism | Caco-2 Cells | Tissue Culture Techniques | HCT116 Cells | Mice, Inbred C57BL | Mice, Transgenic | Phosphoproteins - genetics | Cell Transformation, Neoplastic - metabolism | Homeodomain Proteins - genetics | HT29 Cells | Feedback, Physiological | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Aged | Cell Transformation, Neoplastic - pathology | Colorectal Neoplasms - pathology | Retinoids - pharmacology | Intestinal Mucosa - pathology | Development and progression | Developmental biology | Colorectal cancer | Stem cells | Prevention | Resveratrol | Transplantation | Metastasis | Cancer | Index Medicus
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9. Full Text Long-Term Engraftment of Primary Bone Marrow Stromal Cells Repairs Niche Damage and Improves Hematopoietic Stem Cell Transplantation
by Abbuehl, Jean-Paul and Tatarova, Zuzana and Held, Werner and Huelsken, Joerg
Cell stem cell, ISSN 1934-5909, 08/2017, Volume 21, Issue 2, pp. 241 - 255.e6
hematopoiesis | skeletal stem cells | hematopoietic stem cells | MSC | bone marrow transplantation | Cell & Tissue Engineering | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Mesenchymal Stromal Cells - radiation effects | Stem Cell Niche - radiation effects | Cell Count | Multipotent Stem Cells - metabolism | Male | Gene Expression Profiling | Mesenchymal Stromal Cells - cytology | Time Factors | Hematopoietic Stem Cells - radiation effects | B-Lymphocytes - metabolism | Radiation, Ionizing | Green Fluorescent Proteins - metabolism | B-Lymphocytes - cytology | Lymphopoiesis - radiation effects | B-Lymphocytes - radiation effects | Mice, Inbred C57BL | Cells, Cultured | Hematopoietic Stem Cell Transplantation | Mesenchymal Stromal Cells - metabolism | Hematopoietic Stem Cells - metabolism | Phenotype | Animals | Multipotent Stem Cells - cytology | Hematopoietic Stem Cells - cytology | Mesenchymal Stem Cell Transplantation | Multipotent Stem Cells - radiation effects | Index Medicus
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10. Full Text New aspects of Wnt signaling pathways in higher vertebrates
by Huelsken, Joerg and Birchmeier, Walter
2001, Volume 11, Issue 5, 7
Wnt | patterning | [beta]-catenin | mesoderm | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Proto-Oncogene Proteins - metabolism | Signal Transduction | beta Catenin | Trans-Activators | Vertebrates - embryology | Zebrafish Proteins | Stem Cells - cytology | Wnt Proteins | Stem Cells - metabolism | Embryonic and Fetal Development | Animals | Body Patterning | Cytoskeletal Proteins - metabolism | Cell Differentiation | Mesoderm - metabolism | Vertebrates - metabolism | Wnt protein | Index Medicus
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