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Science, ISSN 0036-8075, 8/2008, Volume 321, Issue 5889, pp. 691 - 696
MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1Rs). MyD88 deficiency in mice leads to susceptibility to... 
Receptors | Phenotypes | Transfection | Cytokines | HEK293 cells | Genes | Cell lines | Fibroblasts | Agonists | Reports | Children | MYD88-DEFICIENT MICE | HERPES-SIMPLEX-VIRUS | PROTECTIVE IMMUNITY | MYELOID DIFFERENTIATION FACTOR-88 | PSEUDOMONAS-AERUGINOSA | MULTIDISCIPLINARY SCIENCES | HUMORAL IMMUNITY | STAPHYLOCOCCUS-AUREUS | AERUGINOSA LUNG INFECTION | HOST RESPONSE | CUTTING EDGE | Humans | Child, Preschool | Male | Mutation, Missense | Bacterial Infections - genetics | Pneumococcal Infections - immunology | Bacterial Infections - immunology | Gene Deletion | Pneumococcal Infections - genetics | Female | Toll-Like Receptors - metabolism | Child | Staphylococcal Infections - genetics | Disease Susceptibility | Cytokines - metabolism | Signal Transduction | Staphylococcal Infections - immunology | Receptors, Interleukin-1 - immunology | Toll-Like Receptors - immunology | Myeloid Differentiation Factor 88 - genetics | Immunity, Innate | Pseudomonas Infections - genetics | Pseudomonas Infections - immunology | Receptors, Interleukin-1 - metabolism | Animals | Myeloid Differentiation Factor 88 - deficiency | Adolescent | Mice | Myeloid Differentiation Factor 88 - metabolism | Cell Line, Transformed | Genetic aspects | Bacterial infections | Pediatrics | Bacteria | Biomedical research | Genetic disorders | Immunology | Pneumococcal Infections | Life Sciences | Toll-Like Receptors | Bacterial Infections | Myeloid Differentiation Factor 88 | Bacteriology | Staphylococcal Infections | Microbiology and Parasitology | Pseudomonas Infections | Receptors, Interleukin-1
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 01/2007, Volume 44, Issue 1, pp. 16 - 23
Background: About 2% of childhood episodes of invasive pneumococcal disease (IPD) are recurrent, and most remain unexplained. Objective: To report two cases of... 
RECEPTOR-ASSOCIATED KINASE-4 | ESSENTIAL MODULATOR MUTATION | C2 DEFICIENCY | STREPTOCOCCUS-PNEUMONIAE | INHERITED DISORDERS | BACTERIAL-INFECTIONS | ANHIDROTIC ECTODERMAL DYSPLASIA | GENETICS & HEREDITY | CONGENITAL ASPLENIA | IMMUNE-DEFICIENCY | SICKLE-CELL-DISEASE | Pneumococcal Infections - drug therapy | Interleukin-1 Receptor-Associated Kinases - metabolism | Recurrence | Interleukin-1 Receptor-Associated Kinases - genetics | Exons | Humans | NF-kappa B - immunology | Child, Preschool | Male | Streptococcus pneumoniae - immunology | Anti-Bacterial Agents - therapeutic use | Pneumococcal Infections - immunology | Streptococcus pneumoniae - chemistry | I-kappa B Kinase - metabolism | Pneumococcal Infections - genetics | Interleukin-1 - immunology | Polymerase Chain Reaction | Child | Signal Transduction | Introns | Pneumococcal Infections - pathology | I-kappa B Kinase - genetics | Ceftriaxone - therapeutic use | Antibody Formation | Immunologic Deficiency Syndromes - genetics | Pneumococcal Vaccines - immunology | DNA, Complementary | Genetic aspects | Children | Research | Gene mutations | Health aspects | Pneumococcal infections | Carbohydrates | Pneumonia | Immunoglobulins | Congenital diseases | Vaccines | Patients | Defects | Streptococcus infections | Genotype & phenotype | Infectious diseases | Immunology | Human immunodeficiency virus--HIV | Meningitis | Mutation | Original
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 10/2007, Volume 204, Issue 10, pp. 2407 - 2422
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2011, Volume 128, Issue 3, pp. 610 - 617.e4
Journal Article
Journal of Urology, The, ISSN 0022-5347, 2009, Volume 181, Issue 4, pp. 1571 - 1580
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 11/2005, Volume 41, Issue Supplement_7, pp. S436 - S439
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 11/2005, Volume 41, pp. S436 - S439
Septicemia is a life-threatening condition that may lead to sepsis and even septic shock. This cascade is usually accompanied by a pronounced inflammatory... 
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 11/2005, Volume 41, Issue 10, p. S436
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 01/2007, Volume 44, Issue 1, pp. 16 - 23
BACKGROUND: About 2% of childhood episodes of invasive pneumococcal disease (IPD) are recurrent, and most remain unexplained. OBJECTIVE: To report two cases of... 
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 10/2007, Volume 204, Issue 10, pp. 2407 - 2422
Human interleukin (IL) 1 receptor-associated kinase 4 (IRAK-4) deficiency is a recently discovered primary immunodeficiency that impairs Toll/IL-1R immunity,... 
Journal Article
Journal of Endotoxin Research, ISSN 0968-0519, 2005, Volume 11, Issue 4, pp. 220 - 224
Journal Article
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