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1. Full Text Comprehensive analyses of tumor immunity: Implications for cancer immunotherapy
by Li, Bo and Severson, Eric and Pignon, Jean-Christophe and Zhao, Haoquan and Li, Taiwen and Novak, Jesse and Jiang, Peng and Shen, Hui and Aster, Jon C and Rodig, Scott and Signoretti, Sabina and Liu, Jun S and Liu, X.Shirley
Genome Biology, ISSN 1474-7596, 08/2016, Volume 17, Issue 1, pp. 174 - 174
Cancer immunotherapies | Cancer vaccine | Tumor immune infiltration | Cancer immunity | Checkpoint blockade | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Neoplasms - metabolism | Immunotherapy - methods | Disease Susceptibility | Signal Transduction | Humans | Gene Expression Regulation, Neoplastic | Databases, Genetic | Immune System - cytology | Molecular Targeted Therapy | Biomarkers, Tumor | Immunity | Genetic Variation | Neoplasms - therapy | Neoplasms - genetics | Immune System - metabolism | Models, Biological | Neoplasms - immunology | Immune System - immunology | Lymphocytes, Tumor-Infiltrating - metabolism | Lymphocytes, Tumor-Infiltrating - immunology | CD8 antigen | Genomics | Genomes | Lymphocytes T | Vaccines | Drug resistance | Metastases | Ovarian cancer | Cancer vaccines | CTLA-4 protein | Lymphocytes | Immunotherapy | Genetic analysis | Cell cycle | DNA methylation | Immune system | Dendritic cells | Tumor-infiltrating lymphocytes | Neutrophils | Melanoma | Non-small cell lung carcinoma | Breast cancer | Gene expression | Ribonucleic acid--RNA | Lymphoma | Immune checkpoint | Medical prognosis | Computer applications | Methods | Index Medicus
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2. Full Text Genome-Wide and Organ-Specific Landscapes of Epigenetic Modifications and Their Relationships to mRNA and Small RNA Transcriptomes in Maize
by Xiangfeng Wang and Axel A. Elling and Xueyong Li and Ning Li and Zhiyu Peng and Guangming He and Hui Sun and Yijun Qi and X. Shirley Liu and Xing Wang Deng
The Plant cell, ISSN 1040-4651, 4/2009, Volume 21, Issue 4, pp. 1053 - 1069
MicroRNA | DNA | Genes | Small interfering RNA | Corn | Epigenetics | Histones | Genomes | Nucleotides | Methylation | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Cell Biology | Zea mays - genetics | Epigenesis, Genetic | MicroRNAs - metabolism | Gene Expression Profiling | Genome, Plant | RNA, Messenger - metabolism | RNA, Plant - metabolism | RNA, Small Interfering - chemistry | DNA Methylation | Sequence Analysis, RNA | RNA, Plant - chemistry | Gene Expression Regulation, Plant | RNA, Messenger - chemistry | Histones - metabolism | Zea mays - metabolism | Nucleic Acid Conformation | MicroRNAs - chemistry | RNA, Small Interfering - metabolism | Epigenetic inheritance | Genetic aspects | Research | Plant genetics | Index Medicus
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3. Full Text Viral Etiology of Acute Exacerbations of COPD in Hong Kong
by Ko, Fanny W.S and Ip, Margaret and Chan, Paul K.S and Chan, Michael C.H and To, Kin-Wang and Ng, Susanna S.S and Chau, Shirley S.L and Tang, Julian W and Hui, David S.C
Chest, ISSN 0012-3692, 09/2007, Volume 132, Issue 3, pp. 900 - 908
acute exacerbation | viruses | COPD | Acute exacerbation | Viruses | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Cardiology. Vascular system | Biological and medical sciences | Medical sciences | Chronic obstructive pulmonary disease, asthma | Pneumology | Pulmonary Disease, Chronic Obstructive - mortality | Acute Disease | RNA Viruses - isolation & purification | Prospective Studies | Follow-Up Studies | Forced Expiratory Volume - physiology | Hong Kong | Humans | Pulmonary Disease, Chronic Obstructive - virology | Male | Hospitalization | Pulmonary Disease, Chronic Obstructive - physiopathology | Positive-Pressure Respiration | Nasopharynx - virology | Polymerase Chain Reaction | Aged, 80 and over | Female | Aged | Polymerase chain reaction | Lung diseases, Obstructive | Usage | Causes of | Research | Identification and classification | Index Medicus | Abridged Index Medicus | NPPV, noninvasive positive pressure ventilation | GOLD, Global Initiative for Chronic Obstructive Lung Disease | MDCK, Mardin Darby canine kidney | AECOPD, acute exacerbations of COPD | CXR, chest radiograph | PCR, polymerase chain reaction | NPA, nasopharyngeal aspirate | RSV, respiratory syncytial virus
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4. Full Text Chromatin structure analyses identify miRNA promoters
by Ozsolak, Fatih and Poling, Laura L and Wang, Zhengxin and Liu, Hui and Liu, X. Shirley and Roeder, Robert G and Zhang, Xinmin and Song, Jun S and Fisher, David E
Genes & development, ISSN 0890-9369, 11/2008, Volume 22, Issue 22, pp. 3172 - 3183
Promoter | Chromatin | MicroRNA | Transcription | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Luciferases - metabolism | Humans | Gene Expression Regulation, Neoplastic | Nucleosomes - genetics | Promoter Regions, Genetic - genetics | Recombinant Fusion Proteins - metabolism | Luciferases - genetics | Transfection | Chromatin Immunoprecipitation | RNA Interference | Cloning, Molecular | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Transcription, Genetic | MicroRNAs - genetics | HeLa Cells | Chromatin - genetics | Promoters (Genetics) | RNA | Analysis | Research | Genetic transcription | Structure | Index Medicus | microRNA | Research Paper | promoter | chromatin
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5. Full Text New mechanistic insights into osmium-based tamoxifen derivatives
by Shirley Lee, Hui Zhi and Chau, François and Top, Siden and Jaouen, Gérard and Vessières, Anne and Labbé, Eric and Buriez, Olivier
Electrochimica acta, ISSN 0013-4686, 04/2019, Volume 302, pp. 130 - 136
Cyclic voltammetry | Anti-cancer | Tamoxifen | Osmium | Bioorganometallic | Electrochemistry | Physical Sciences | Science & Technology | Electrochemical reactions | Derivatives (Financial instruments) | Analysis | Quinone | Electrochemical analysis | Oxidation | Derivatives | Chemical Sciences
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6. Full Text NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity
by Moriyama, Takaya and Nishii, Rina and Perez-Andreu, Virginia and Yang, Wenjian and Klussmann, Federico Antillon and Zhao, Xujie and Lin, Ting-Nien and Hoshitsuki, Keito and Nersting, Jacob and Kihira, Kentaro and Hofmann, Ute and Komada, Yoshihiro and Kato, Motohiro and McCorkle, Robert and Li, Lie and Koh, Katsuyoshi and Najera, Cesar Rolando and Kham, Shirley Kow-Yin and Isobe, Tomoya and Chen, Zhiwei and Chiew, Edwynn Kean-Hui and Bhojwani, Deepa and Jeffries, Cynthia and Lu, Yan and Schwab, Matthias and Inaba, Hiroto and Pui, Ching-Hon and Relling, Mary V and Manabe, Atsushi and Hori, Hiroki and Schmiegelow, Kjeld and Yeoh, Allen E.J and Evans, William E and Yang, Jun J
Nature genetics, ISSN 1061-4036, 03/2016, Volume 48, Issue 4, pp. 367 - 373
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Pyrophosphatases - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Antimetabolites, Antineoplastic - therapeutic use | Genetic Association Studies | Mercaptopurine - therapeutic use | Humans | Antimetabolites, Antineoplastic - adverse effects | Mercaptopurine - adverse effects | Pyrophosphatases - genetics | Polymorphism, Single Nucleotide | Hematopoiesis - drug effects | Drug metabolism | Purines | Genetic aspects | Properties | Health aspects | Genetic polymorphisms | Haplotypes | Pediatrics | Medical research | Toxicity | Genes | Leukemia | Clinical trials | Cytotoxicity | Genomes | Metabolism | Lymphoma | Children & youth | Proteins | Studies | Consortia | Hospitals | Metabolites | Drug dosages | Deoxyribonucleic acid--DNA | Cancer | Index Medicus
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7. Full Text Intracellular Localization of an Osmocenyl‐Tamoxifen Derivative in Breast Cancer Cells Revealed by Synchrotron Radiation X‐ray Fluorescence Nanoimaging
by Fus, Florin and Yang, Yang and Lee, Hui Zhi Shirley and Top, Siden and Carriere, Marie and Bouron, Alexandre and Pacureanu, Alexandra and da Silva, Julio Cesar and Salmain, Michèle and Vessières, Anne and Cloetens, Peter and Jaouen, Gérard and Bohic, Sylvain
Angewandte Chemie (International ed.), ISSN 1433-7851, 03/2019, Volume 58, Issue 11, pp. 3461 - 3465
osmium | bioorganometallic chemistry | X-ray fluorescence | synchrotron | elemental tomography | Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Fluorescence | Breast cancer | X-ray spectroscopy | Tamoxifen | Cancer cells | Radiation | Membranes | Metals | Iron | Mapping | Electrostatic properties | Lipophilic | X radiation | Intracellular | Localization | Synchrotron radiation | Cancer | Index Medicus | Life Sciences | Cellular Biology | Chemical Sciences | Coordination chemistry | Radiochemistry
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8. Full Text Genome-Wide Analysis of Histone Modifications： H3K4me2, H3K4me3, H3K9ac, and H3K27ac in Oryza sativa L. Japonica
by Zhou Du Hui Li Qiang Wei Xin Zhao Chunchao Wang Qilin Zhu Xin Yi Wenying Xua X. Shirley Liu Weiwei Jin Zhen Su
Molecular plant, ISSN 1674-2052, 2013, Volume 6, Issue 5, pp. 1463 - 1472
组蛋白修饰 | 转录因子结合位点 | 转录起始位点 | 粳稻 | 基因转录 | 基因组分析 | 水稻基因组 | 染色质免疫沉淀 | genomics | chromatin structure and remodeling | rice | gene regulation | epigenetics | bioinformatics | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Reproducibility of Results | Genome, Plant - genetics | Oryza - metabolism | Molecular Sequence Annotation | Molecular Sequence Data | Binding Sites - genetics | Sequence Analysis, DNA | Deoxyribonucleases - metabolism | Transcription Factors - metabolism | Oryza - genetics | Genes, Plant - genetics | Base Sequence | Transcription Initiation Site | DNA Transposable Elements - genetics | Transcription, Genetic | Lysine - metabolism | Protein Processing, Post-Translational | Histones - metabolism | Studies | Chromatin | Transcription factors | Genomes | Gene expression | Rice | Index Medicus
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9. Full Text Prospective comparison of three predictive rules for assessing severity of community-acquired pneumonia in Hong Kong
by Shin, Yan Man and Lee, Nelson and Ip, Margaret and Antonio, Gregory E and Chau, Shirley S.L and Mak, Paulina and Graham, Colin A and Zhang, Mingdong and Lui, Grace and Chan, Paul K. S and Ahuja, Anil T and Hui, David S and Sung, Joseph J. Y and Rainer, Timothy H
Thorax, ISSN 0040-6376, 04/2007, Volume 62, Issue 4, pp. 348 - 353
Life Sciences & Biomedicine | Respiratory System | Science & Technology | Biological and medical sciences | Medical sciences | Pneumology | Community-Acquired Infections - diagnosis | Severity of Illness Index | Community-Acquired Infections - mortality | Predictive Value of Tests | Prognosis | Prospective Studies | Humans | Middle Aged | Male | Pneumonia - mortality | Hong Kong - epidemiology | Pneumonia - diagnosis | Adolescent | Aged, 80 and over | Adult | Female | Aged | Pneumonia | Hong Kong | Bacterial pneumonia | Patient outcomes | Mortality | Development and progression | Research | Index Medicus | Respiratory Infection
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10. Full Text Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
by Chouchani, Edward T and Pell, Victoria R and Gaude, Edoardo and Aksentijević, Dunja and Sundier, Stephanie Y and Robb, Ellen L and Logan, Angela and Nadtochiy, Sergiy M and Ord, Emily N. J and Smith, Anthony C and Eyassu, Filmon and Shirley, Rachel and Hu, Chou-Hui and Dare, Anna J and James, Andrew M and Rogatti, Sebastian and Hartley, Richard C and Eaton, Simon and Costa, Ana S. H and Brookes, Paul S and Davidson, Sean M and Duchen,