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by Adema, Coen M and Hillier, LaDeana W and Jones, Catherine S and Loker, Eric S and Knight, Matty and Minx, Patrick and Oliveira, Guilherme and Raghavan, Nithya and Shedlock, Andrew and do Amaral, Laurence Rodrigues and Arican-Goktas, Halime D and Assis, Juliana G and Baba, Elio Hideo and Baron, Olga L and Bayne, Christopher J and Bickham-Wright, Utibe and Biggar, Kyle K and Blouin, Michael and Bonning, Bryony C and Botka, Chris and Bridger, Joanna M and Buckley, Katherine M and Buddenborg, Sarah K and Lima Caldeira, Roberta and Carleton, Julia and Carvalho, Omar S and Castillo, Maria G and Chalmers, Iain W and Christensens, Mikkel and Clifton, Sandra and Cosseau, Celine and Coustau, Christine and Cripps, Richard M and Cuesta-Astroz, Yesid and Cummins, Scott F and di Stefano, Leon and Dinguirard, Nathalie and Duval, David and Emrich, Scott and Feschotte, Cédric and Feyereisen, Rene and FitzGerald, Peter and Fronick, Catrina and Fulton, Lucinda and Galinier, Richard and Gava, Sandra G and Geusz, Michael and Geyer, Kathrin K and Giraldo-Calderón, Gloria I and de Souza Gomes, Matheus and Gordy, Michelle A and Gourbal, Benjamin and Grunau, Christoph and Hanington, Patrick C and Hoffmann, Karl F and Hughes, Daniel and Humphries, Judith and Jackson, Daniel J and Jannotti-Passos, Liana K and de Jesus Jeremias, Wander and Jobling, Susan and Kamel, Bishoy and Kapusta, Aurélie and Kaur, Satwant and Koene, Joris M and Kohn, Andrea B and Lawson, Dan and Lawton, Scott P and Liang, Di and Limpanont, Yanin and Liu, Sijun and Lockyer, Anne E and Lovato, TyAnna L and Ludolf, Fernanda and Magrini, Vince and McManus, Donald P and Medina, Monica and Misra, Milind and Mitta, Guillaume and Mkoji, Gerald M and Montague, Michael J and Montelongo, Cesar and Moroz, Leonid L and Munoz-Torres, Monica C and Niazi, Umar and Noble, Leslie R and Oliveira, Francislon S and Pais, Fabiano S and Papenfuss, Anthony T and Peace, Rob and Pena, Janeth J and Pila, Emmanuel A and Quelais, Titouan and Raney, Brian J and Rast, Jonathan P and Rollinson, David and Rosse, Izinara C and Rotgans, Bronwyn and Routledge, Edwin J and Ryan, Kathryn M and ...
Nature communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, p. 15451
Journal Article
by Jones, Gregory T and Tromp, Gerard and Kuivaniemi, Helena and Gretarsdottir, Solveig and Baas, Annette F and Giusti, Betti and Strauss, Ewa and van‘t Hof, Femke N.G and Webb, Thomas R and Erdman, Robert and Ritchie, Marylyn D and Elmore, James R and Verma, Anurag and Pendergrass, Sarah and Kullo, Iftikhar J and Ye, Zi and Peissig, Peggy L and Gottesman, Omri and Verma, Shefali S and Malinowski, Jennifer and Rasmussen-Torvik, Laura J and Borthwick, Kenneth M and Smelser, Diane T and Crosslin, David R and de Andrade, Mariza and Ryer, Evan J and McCarty, Catherine A and Böttinger, Erwin P and Pacheco, Jennifer A and Crawford, Dana C and Carrell, David S and Gerhard, Glenn S and Franklin, David P and Carey, David J and Phillips, Victoria L and Williams, Michael J.A and Wei, Wenhua and Blair, Ross and Hill, Andrew A and Vasudevan, Thodor M and Lewis, David R and Thomson, Ian A and Krysa, Jo and Hill, Geraldine B and Roake, Justin and Merriman, Tony R and Oszkinis, Grzegorz and Galora, Silvia and Saracini, Claudia and Abbate, Rosanna and Pulli, Raffaele and Pratesi, Carlo and Saratzis, Athanasios and Verissimo, Ana R and Bumpstead, Suzannah and Badger, Stephen A and Clough, Rachel E and Cockerill, Gillian and Hafez, Hany and Scott, D. Julian A and Futers, T. Simon and Romaine, Simon P.R and Bridge, Katherine and Griffin, Kathryn J and Bailey, Marc A and Smith, Alberto and Thompson, Matthew M and van Bockxmeer, Frank M and Matthiasson, Stefan E and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Blankensteijn, Jan D and Teijink, Joep A.W and Wijmenga, Cisca and de Graaf, Jacqueline and Kiemeney, Lambertus A and Lindholt, Jes S and Hughes, Anne and Bradley, Declan T and Stirrups, Kathleen and Golledge, Jonathan and Norman, Paul E and Powell, Janet T and Humphries, Steve E and Hamby, Stephen E and Goodall, Alison H and Nelson, Christopher P and Sakalihasan, Natzi and Courtois, Audrey and Ferrell, Robert E and Eriksson, Per and Folkersen, Lasse and Franco-Cereceda, Anders and Eicher, John D and Johnson, Andrew D and Betsholtz, Christer and Ruusalepp, Arno and Franzén, Oscar and Schadt, Eric E and Björkegren, Johan L.M and ... and Cardiogenics Consortium and Int Consortium Blood Pressure
Circulation research, ISSN 1524-4571, 2017, Volume 120, Issue 2, pp. 341 - 353
Journal Article
by Franceschini, Nora and Giambartolomei, Claudia and de Vries, Paul S and Finan, Chris and Bis, Joshua C and Huntley, Rachael P and Lovering, Ruth C and Tajuddin, Salman M and Winkler, Thomas W and Graff, Misa and Kavousi, Maryam and Dale, Caroline and Smith, Albert V and Hofer, Edith and van Leeuwen, Elisabeth M and Nolte, Ilja M and Lu, Lingyi and Scholz, Markus and Sargurupremraj, Muralidharan and Pitkänen, Niina and Franzén, Oscar and Joshi, Peter K and Noordam, Raymond and Marioni, Riccardo E and Hwang, Shih-Jen and Musani, Solomon K and Schminke, Ulf and Palmas, Walter and Isaacs, Aaron and Correa, Adolfo and Zonderman, Alan B and Hofman, Albert and Teumer, Alexander and Cox, Amanda J and Uitterlinden, André G and Wong, Andrew and Smit, Andries J and Newman, Anne B and Britton, Annie and Ruusalepp, Arno and Sennblad, Bengt and Hedblad, Bo and Pasaniuc, Bogdan and Penninx, Brenda W and Langefeld, Carl D and Wassel, Christina L and Tzourio, Christophe and Fava, Cristiano and Baldassarre, Damiano and O’Leary, Daniel H and Teupser, Daniel and Kuh, Diana and Tremoli, Elena and Mannarino, Elmo and Grossi, Enzo and Boerwinkle, Eric and Schadt, Eric E and Ingelsson, Erik and Veglia, Fabrizio and Rivadeneira, Fernando and Beutner, Frank and Chauhan, Ganesh and Heiss, Gerardo and Snieder, Harold and Campbell, Harry and Völzke, Henry and Markus, Hugh S and Deary, Ian J and Jukema, J. Wouter and de Graaf, Jacqueline and Price, Jacqueline and Pott, Janne and Hopewell, Jemma C and Liang, Jingjing and Thiery, Joachim and Engmann, Jorgen and Gertow, Karl and Rice, Kenneth and Taylor, Kent D and Dhana, Klodian and Kiemeney, Lambertus A. L. M and Lind, Lars and Raffield, Laura M and Launer, Lenore J and Holdt, Lesca M and Dörr, Marcus and Dichgans, Martin and Traylor, Matthew and Sitzer, Matthias and Kumari, Meena and Kivimaki, Mika and Nalls, Mike A and Melander, Olle and Raitakari, Olli and Franco, Oscar H and Rueda-Ochoa, Oscar L and Roussos, Panos and Whincup, Peter H and Amouyel, Philippe and Giral, Philippe and ... and MEGASTROKE Consortium and Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap and Göteborgs universitet and Gothenburg University and Institute of Biomedicine, Department of Pathology and Core Facilities, Bioinformatics and Sahlgrenska Academy and Institutionen för biomedicin, avdelningen för patologi and Sahlgrenska akademin and Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 5141 - 14
Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and coronary heart... 
HEART | METAANALYSIS | VARIANTS | INTEGRATIVE ANALYSIS | MULTIDISCIPLINARY SCIENCES | CORONARY-ARTERY-DISEASE | GENE-PRODUCT | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease - genetics | Plaque, Atherosclerotic - genetics | Carotid Intima-Media Thickness | Humans | Risk Factors | ADAMTS9 Protein - genetics | Lod Score | Amino Acid Oxidoreductases - genetics | Coronary Disease - pathology | Coronary Disease - genetics | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Plaque, Atherosclerotic - pathology | Quantitative Trait Loci - genetics | Heart | Stroke | Genes | Cardiovascular disease | Genomes | Regression analysis | Tissues | Loci | Coronary artery disease | Ischemia | Arteriosclerosis | Atherosclerosis | Regulatory mechanisms (biology) | Carotid artery | Cardiovascular diseases | Heart diseases | coronary artery disease | B scan | single nucleotide polymorphism | ischemic heart disease | heart atrium appendage | genetic regulation | STEAP2-AS1 gene | epigenetics | carotid atherosclerosis | protein | genetic risk | genetic correlation | genetic susceptibility | PIK3CG gene | cell component | cardiovascular system | brain ischemia | CFDP1-TMEM170A gene | gene | TMCO5B gene | ADAMTS9 protein | human cell | chromosome 8 | cerebrovascular accident | internal mammary artery | adipose derived stem cell | expression quantitative trait locus | genetic analysis | chromosome 7 | clinical outcome | apolipoprotein E | nonhuman | gene expression | unclassified drug | EDNRA gene | Article | cell | gene control | Medicinsk genetik | Medical Genetics | artery wall | regulatory mechanism | cell adhesion | genomics | tibial artery | loxl4 protein | human | cardiovascular disease | mesenchymal stem cell | stroke | disease association | arterial wall thickness | gene frequency | genetic epidemiology | genetic variability | gene locus | genome-wide association study
Journal Article
by Schmidt, Amand F and Swerdlow, Daniel I and Holmes, Michael V and Patel, Riyaz S and Fairhurst-Hunter, Zammy and Lyall, Donald M and Hartwig, Fernando Pires and Horta, Bernardo Lessa and Hyppönen, Elina and Power, Christine and Moldovan, Max and van Iperen, Erik and Hovingh, G Kees and Demuth, Ilja and Norman, Kristina and Steinhagen-Thiessen, Elisabeth and Demuth, Juri and Bertram, Lars and Liu, Tian and Coassin, Stefan and Willeit, Johann and Kiechl, Stefan and Willeit, Karin and Mason, Dan and Wright, John and Morris, Richard and Wanamethee, Goya and Whincup, Peter and Ben-Shlomo, Yoav and McLachlan, Stela and Price, Jackie F and Kivimaki, Mika and Welch, Catherine and Sanchez-Galvez, Adelaida and Marques-Vidal, Pedro and Nicolaides, Andrew and Panayiotou, Andrie G and Onland-Moret, N Charlotte and van der Schouw, Yvonne T and Matullo, Giuseppe and Fiorito, Giovanni and Guarrera, Simonetta and Sacerdote, Carlotta and Wareham, Nicholas J and Langenberg, Claudia and Scott, Robert and Luan, Jian'an and Bobak, Martin and Malyutina, Sofia and Pająk, Andrzej and Kubinova, Ruzena and Tamosiunas, Abdonas and Pikhart, Hynek and Husemoen, Lise Lotte Nystrup and Grarup, Niels and Pedersen, Oluf and Hansen, Torben and Linneberg, Allan and Simonsen, Kenneth Starup and Cooper, Jackie and Humphries, Steve E and Brilliant, Murray and Kitchner, Terrie and Hakonarson, Hakon and Carrell, David S and McCarty, Catherine A and Kirchner, H Lester and Larson, Eric B and Crosslin, David R and de Andrade, Mariza and Roden, Dan M and Denny, Joshua C and Carty, Cara and Hancock, Stephen and Attia, John and Holliday, Elizabeth and O'Donnell, Martin and Yusuf, Salim and Chong, Michael and Pare, Guillaume and van der Harst, Pim and Said, M Abdullah and Eppinga, Ruben N and Verweij, Niek and Snieder, Harold and Christen, Tim and Mook-Kanamori, Dennis O and Gustafsson, Stefan and Lind, Lars and Ingelsson, Erik and Pazoki, Raha and Franco, Oscar and Hofman, Albert and Uitterlinden, Andre and Dehghan, Abbas and Teumer, Alexander and Baumeister, Sebastian and Dörr, Marcus and Lerch, Markus M and Völker, Uwe and ... and UCLEB consortium and LifeLines Cohort study group and UCLEB Consortium and LifeLines Cohort Study Grp
The lancet. Diabetes & endocrinology, ISSN 2213-8587, 2017, Volume 5, Issue 2, pp. 97 - 105
Journal Article
by Locke, Adam E and Kahali, Bratati and Berndt, Sonja I and Justice, Anne E and Pers, Tune H and Day, Felix R and Powell, Corey and Vedantam, Sailaja and Buchkovich, Martin L and Yang, Jian and Croteau-Chonka, Damien C and Esko, Tonu and Fall, Tove and Ferreira, Teresa and Gustafsson, Stefan and Kutalik, Zoltán and Luan, Jian’an and Mägi, Reedik and Randall, Joshua C and Winkler, Thomas W and Wood, Andrew R and Workalemahu, Tsegaselassie and Faul, Jessica D and Smith, Jennifer A and Hua Zhao, Jing and Zhao, Wei and Chen, Jin and Fehrmann, Rudolf and Hedman, Åsa K and Karjalainen, Juha and Schmidt, Ellen M and Absher, Devin and Amin, Najaf and Anderson, Denise and Beekman, Marian and Bolton, Jennifer L and Bragg-Gresham, Jennifer L and Buyske, Steven and Demirkan, Ayse and Deng, Guohong and Ehret, Georg B and Feenstra, Bjarke and Feitosa, Mary F and Fischer, Krista and Goel, Anuj and Gong, Jian and Jackson, Anne U and Kanoni, Stavroula and Kleber, Marcus E and Kristiansson, Kati and Lim, Unhee and Lotay, Vaneet and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Medland, Sarah E and Nalls, Michael A and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Peters, Marjolein J and Prokopenko, Inga and Shungin, Dmitry and Stančáková, Alena and Strawbridge, Rona J and Ju Sung, Yun and Tanaka, Toshiko and Teumer, Alexander and Trompet, Stella and van der Laan, Sander W and van Setten, Jessica and Van Vliet-Ostaptchouk, Jana V and Wang, Zhaoming and Yengo, Loïc and Zhang, Weihua and Isaacs, Aaron and Albrecht, Eva and Ärnlöv, Johan and Arscott, Gillian M and Attwood, Antony P and Bandinelli, Stefania and Barrett, Amy and Bas, Isabelita N and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blagieva, Roza and Blüher, Matthias and Böhringer, Stefan and Bonnycastle, Lori L and Böttcher, Yvonne and Boyd, Heather A and Bruinenberg, Marcel and Caspersen, Ida H and Ida Chen, Yii-Der and Clarke, Robert and Warwick Daw, E and de Craen, Anton J. M and Delgado, Graciela and Dimitriou, Maria and ... and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GLGC and The GENIE Consortium and The AGEN-BMI Working Group and The MIGen Consortium and The MuTHER Consortium and The LifeLines Cohort Study and ADIPOGen Consortium and PAGE Consortium and LifeLines Cohort Study and MIGen Consortium and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and CKDGen Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and AGEN-BMI Working Grp and GLGC and International Endogene Consortium and AGEN-BMI Working Group
Nature (London), ISSN 1476-4687, 2015, Volume 518, Issue 7538, pp. 197 - 206
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and... 
INDIVIDUALS | PROVIDES INSIGHTS | METAANALYSIS | VARIANTS | MULTIDISCIPLINARY SCIENCES | HIPPOCAMPAL | GLYCEMIC TRAITS | ARCHITECTURE | TOPIRAMATE | LOCI | GENOME-WIDE ASSOCIATION | Body Mass Index | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Age Factors | Humans | Male | Continental Population Groups - genetics | Adiposity - genetics | Obesity - genetics | Europe - ethnology | Obesity - metabolism | Insulin - metabolism | Synapses - metabolism | Polymorphism, Single Nucleotide - genetics | Female | Glutamic Acid - metabolism | Energy Metabolism - genetics | Adipogenesis - genetics | Insulin Secretion | Quantitative Trait Loci - genetics | Body mass index | Obesity | Genetic research | Genetic aspects | Research | Diabetes | Gene expression | Health aspects | Studies | Genomics | Genetics | Biology | Genomes | Metabolic disorders | Meta-analysis | Medical and Health Sciences | Insulin: metabolism | Medicin och hälsovetenskap | Obesity: genetics | Europe: ethnology | Glutamic Acid: metabolism | Genetic Predisposition to Disease: genetics | Single Nucleotide: genetics | Klinisk medicin | Synapses: metabolism | Adiposity: genetics | Obesity: metabolism | Clinical Medicine | Energy Metabolism: genetics | Endokrinologi och diabetes | Quantitative Trait Loci: genetics | Insulin: secretion | Adipogenesis: genetics | Polymorphism | Continental Population Groups: genetics | Endocrinology and Diabetes
Journal Article
Arthritis & rheumatology (Hoboken, N.J.), ISSN 2326-5191, 2016, Volume 68, Issue 8, pp. 1887 - 1898
Journal Article
by Franceschini, Nora and Giambartolomei, C and Vries, Paul and Finan, Chris and Bis, Joshua and Huntley, R.P and Lovering, R.C and Tajuddin, S.M and Winkler, Thomas W and Graff, M and Kavousi, Maryam and Dale, C and Smith, Albert and Hofer, Edith and Leeuwen, Elisa and Nolte, Ilja and Lu, L and Scholz, Markus and Sargurupremraj, M and Pitkanen, Niina and Franzén, O and Joshi, Peter and Noordam, R and Marioni, Riccardo and Hwang, S.-J and Musani, S.K and Schminke, Ulf and Palmas, Walter and Isaacs, Aaron and Correa, D.D and Zonderman, A.B and Hofman, Albert and Teumer, Alexander and Cox, A.J and Uitterlinden, Ané and Wong, A and Smit, Anies and Newman, Anne B and Britton, A.R and Ruusalepp, A and Sennblad, Bengt and Hedblad, Bo and Pasaniuc, B and Penninx, Brenda and Langefeld, C.D and Wassel, Christina and Tzourio, Christophe and Fava, Cristiano and Baldassarre, Damiano and O’Leary, D.H and Teupser, Daniel and Kuh, D and Tremoli, Elena and Mannarino, Elmo and Grossi, E and Boerwinkle, Eric and Schadt, E.E and Ingelsson, Erik and Veglia, Fabrizio and Rivadeneira Ramirez, Fernando and Beutner, Frank and Chauhan, G and Heiss, Gerardo and Snieder, Harold and Campbell, Harry and Völzke, Henry and Markus, Hugh and Deary, Ian J and Jukema, Jan Wouter and Graaf, Jacqueline and Price, J and Pott, J and Hopewell, J and Liang, J and Thiery, Joachim and Engmann, Jorgen and Gertow, Karl and Rice, Kenneth and Taylor, Kent and Dhana, Klodian and Kiemeney, L.A.L.M and Kao, Wen and Raffield, L.M and Launer, Lenore and Holdt, Lesca and Dörr, Marcus and Kubisch, Christian and Traylor, Matthew and Sitzer, Matthias and Kumari, M and Kivimaki, Mika and Nalls, Michael and Melander, O and Raitakari, Olli and Franco, Oscar and Rueda-Ochoa, O.L and Roussos, Alexana and Whincup, Peter and Amouyel, Philippe and Giral, P and ... and et al
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1
textabstractCarotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and... 
Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article