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1. Full Text Electrokinetic diffusioosmosis of viscoelastic Phan-Thien–Tanner liquids in slit microchannels
by Huang, Hsin-Fu and Yao, Cheng-Hung
Journal of non-Newtonian fluid mechanics, ISSN 0377-0257, 04/2014, Volume 206, pp. 1 - 10
Concentration gradient driven | Electrical double layers | Simplified Phan-Thien–Tanner model | Electrokinetic diffusioosmosis | Viscoelastic liquids | High zeta potentials | Simplified phan-thien-tanner model | Mechanics | Technology | Science & Technology | Liquids | Flow rate | Zeta potential | Flow velocity | Mathematical models | Lubrication | Deborah number | Walls
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2. Targeting virulence: A new paradigm for antimicrobial therapy
by Clatworthy, Anne E and Pierson, Emily and Hung, Deborah T
Nature chemical biology, ISSN 1552-4450, 2007, Volume 3, Issue 9, pp. 541 - 548
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Virulence - drug effects | Genes, Bacterial | Quorum Sensing - drug effects | Virulence - genetics | Anti-Infective Agents - pharmacology | Anti-Infective Agents - therapeutic use | Bacterial Adhesion - drug effects | Virulence Factors - antagonists & inhibitors | Drug Delivery Systems | Biochemistry | Infections | Biomedical research | Microbiology | Drug resistance | Alternatives | Infection | Reviews | Antibiotics | Antibiotic resistance | Antimicrobial agents | Drug development | virulence factors
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3. Full Text scDual-Seq: Mapping the gene regulatory program of Salmonella infection by host and pathogen single-cell RNA-sequencing
by Avital, Gal and Avraham, Roi and Fan, Amy and Hashimshony, Tamar and Hung, Deborah T and Yanai, Itai
Genome Biology, ISSN 1474-7596, 10/2017, Volume 18, Issue 1, pp. 200 - 200
Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Sequence Analysis, RNA - methods | Macrophages - metabolism | Animals | Salmonella typhimurium - genetics | Mice, Inbred C57BL | Gene Expression Regulation | Gene Expression Profiling - methods | Mice | Single-Cell Analysis | Macrophages - microbiology | Subpopulations | Salmonella | Pathogens | Stem cells | Infections | Genomes | Gene expression | Macrophages | Gene mapping | Ribonucleic acid--RNA | Deoxyribonucleic acid--DNA | Methods | Index Medicus
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4. Full Text Nucleic acid detection with CRISPR-Cas13a/C2c2
by Gootenberg, Jonathan S and Abudayyeh, Omar O and Lee, Jeong Wook and Essletzbichler, Patrick and Dy, Aaron J and Joung, Julia and Verdine, Vanessa and Donghia, Nina and Daringer, Nichole M and Freije, Catherine A and Myhrvold, Cameron and Bhattacharyya, Roby P and Livny, Jonathan and Regev, Aviv and Koonin, Eugene V and Hung, Deborah T and Sabeti, Pardis C and Collins, James J and Zhang, Feng
Science (American Association for the Advancement of Science), ISSN 0036-8075, 04/2017, Volume 356, Issue 6336, pp. 438 - 442
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Circulating Tumor DNA - analysis | Zika Virus - genetics | Circulating Tumor DNA - genetics | Ribonucleases - chemistry | Humans | Bacterial Proteins - chemistry | RNA, Viral - analysis | RNA Cleavage | Zika Virus - isolation & purification | Dengue Virus - genetics | Bacteria - isolation & purification | RNA, Viral - genetics | Zika Virus Infection - diagnosis | Neoplasms - genetics | Point-of-Care Systems | Clustered Regularly Interspaced Short Palindromic Repeats | DNA, Bacterial - analysis | Bacteria - pathogenicity | Dengue Virus - isolation & purification | Mutation | Dengue - diagnosis | Methods | Nucleotide sequencing | DNA sequencing | Vector-borne diseases | Pathogens | CRISPR | Target recognition | Nucleotide sequence | Dengue | Viruses | Zika virus | Nucleic acids | Ribonuclease | Recombinase | Ribonucleic acid--RNA | Sensitivity | Genotyping | Reagents | Bacteria | Deoxyribonucleic acid--DNA | Index Medicus | Amplification | Ribonucleic acids | Deoxyribonucleic acid
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5. Full Text Continuous and High-Throughput Electromechanical Lysis of Bacterial Pathogens Using Ion Concentration Polarization
by Kim, Minseok and Wu, Lidan and Kim, Bumjoo and Hung, Deborah T and Han, Jongyoon
Analytical chemistry (Washington), ISSN 0003-2700, 01/2018, Volume 90, Issue 1, pp. 872 - 880
Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Microfluidic Analytical Techniques - methods | Mycobacterium smegmatis - chemistry | Bacteriolysis | Microfluidic Analytical Techniques - instrumentation | Membranes, Artificial | Electrochemical Techniques - methods | Mechanical Phenomena | Electrochemical Techniques - instrumentation | Escherichia coli K12 - chemistry | Polarization (Electricity) | Nucleic acids | Cell death | Analysis | Water treatment | Ion concentration | Fluid dynamics | Energy recovery | Disinfection | Materials selection | Cells | Mammalian cells | Proteins | Field strength | Lysates | Metabolites | Food industry | Reagents | Lysis | Bacteria | Energy efficiency | Pharmaceutical industry | Electric fields | Index Medicus | ion concentration polarization | electroconvective vortex | disinfection | bacterial lysis | electromechanical lysis
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6. Full Text Small-Molecule Inhibitor of Vibrio cholerae Virulence and Intestinal Colonization
by Deborah T. Hung and Elizabeth A. Shakhnovich and Emily Pierson and John J. Mekalanos
Science (American Association for the Advancement of Science), ISSN 0036-8075, 10/2005, Volume 310, Issue 5748, pp. 670 - 674
Larvae | Microbial colonization | Insect larvae | Virulence | Bacteria | Reports | Infections | Cholera | Toxins | Fat body | Larval development | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Antibiotics (antibacterial agents, antifungal agents) | Microbiology | Applied microbiology | Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents | Virulence - drug effects | Cell Line | Butyrates - pharmacology | Intestine, Small - microbiology | Vibrio cholerae - pathogenicity | Naphthalimides | Transcription Factors - biosynthesis | Naphthalenes - pharmacology | Transcription Factors - drug effects | Bacterial Proteins - drug effects | Microbial Sensitivity Tests | Fimbriae, Bacterial - drug effects | Gene Expression Regulation, Bacterial - drug effects | Cholera Toxin - biosynthesis | Animals | Anti-Bacterial Agents - pharmacology | Bacterial Proteins - biosynthesis | Mice | Vibrio cholerae - drug effects | Cholera - microbiology | Virulence Factors - biosynthesis | Infection | Drug resistance in microorganisms | Care and treatment | Research | Drug therapy | Analysis | Molecules | Colon | Antibiotics | Drug resistance | Gene expression | Index Medicus
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7. Full Text A highly multiplexed and sensitive RNA-seq protocol for simultaneous analysis of host and pathogen transcriptomes
by Avraham, Roi and Haseley, Nathan and Fan, Amy and Bloom-Ackermann, Zohar and Livny, Jonathan and Hung, Deborah T
Nature protocols, ISSN 1754-2189, 08/2016, Volume 11, Issue 8, pp. 1477 - 1491
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Limit of Detection | Bone Marrow Cells - cytology | Salmonella - cytology | Salmonella - genetics | Salmonella - physiology | Gene Expression Profiling - methods | Host-Pathogen Interactions | Sequence Analysis, RNA - methods | Macrophages - metabolism | Animals | Time Factors | RNA, Bacterial - genetics | Mice | Macrophages - microbiology | RNA sequencing | Host-parasite relationships | Usage | Genetic transcription | Analysis | Index Medicus
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8. Full Text Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response
by Grant, Sarah Schmidt and Hung, Deborah T
Virulence, ISSN 2150-5594, 05/2013, Volume 4, Issue 4, pp. 273 - 283
antibiotic tolerance | persisters | persistent bacterial infections | small colony variants | biofilms | oxidative stress | Oxidative stress | Biofilms | Small colony variants | Antibiotic tolerance | Persistent bacterial infections | Persisters | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Oxidative Stress | Humans | Bacteria - drug effects | Anti-Bacterial Agents - metabolism | Bacterial Physiological Phenomena | Bacteria - pathogenicity | Bacterial Infections - microbiology | Index Medicus | Review
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9. Full Text Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses
by Avraham, Roi and Haseley, Nathan and Brown, Douglas and Penaranda, Cristina and Jijon, Humberto B and Trombetta, John J and Satija, Rahul and Shalek, Alex K and Xavier, Ramnik J and Regev, Aviv and Hung, Deborah T
Cell (Cambridge), ISSN 0092-8674, 09/2015, Volume 162, Issue 6, pp. 1309 - 1321
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Host-Pathogen Interactions | Salmonella typhimurium - physiology | Animals | Specific Pathogen-Free Organisms | Mice, Inbred C57BL | Salmonella Infections - immunology | Lipopolysaccharides - metabolism | Salmonella Infections - microbiology | Mice | Interferon Type I - immunology | Macrophages - immunology | Bacteria | Immune response | RNA | Gene expression | Gastrointestinal diseases | Index Medicus | host-pathogen interaction | macrophage | Single-cell RNA-seq | Salmonella typhimurium | Type I interferon response
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10. Full Text Definitions and guidelines for research on antibiotic persistence
by Balaban, Nathalie Q and Helaine, Sophie and Lewis, Kim and Ackermann, Martin and Alidge, Bree and Andersson, Dan I and Brynildsen, Mark P and Bumann, Dirk and Camilli, Anew and Collins, James J and Dehio, Christoph and Fortune, Sarah and Ghigo, Jean-Marc and Hardt, Wolf-Dietrich and Harms, Alexander and Heinemann, Matthias and Hung, Deborah T and Jenal, Urs and Levin, Bruce R and Michiels, Jan and Storz, Gisela and Tan, Man-Wah and Tenson, Tanel and Van Melderen, Laurence and Zinkernagel, Annelies
Nature reviews. Microbiology, ISSN 1740-1526, 07/2019, Volume 17, Issue 7, pp. 441 - 448
CELLS | BACTERIAL PERSISTENCE | INFECTIONS | TOLERANCE | ESCHERICHIA-COLI K-12 | FREQUENCY | RESISTANCE | SALMONELLA | PHENOTYPIC HETEROGENEITY | To be checked by Faculty | MOLECULAR-MECHANISMS | Life Sciences & Biomedicine | Microbiology | Science & Technology | Guidelines as Topic | Bacteria - drug effects | Drug Tolerance | Terminology as Topic | Biomedical Research - methods | Anti-Bacterial Agents - pharmacology | Biomedical Research - standards | Drug resistance in microorganisms | Microbiological research | Pharmacology, Experimental | Research | Heterogeneity | Antibiotics | Failure analysis | Antibiotic resistance | Guidelines | Index Medicus
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11. Full Text Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation
by Goldstein, Daniel and Moskowitz, Alan J and Gelijns, Annetine C and Ailawadi, Gorav and Parides, Michael K and Perrault, Louis P and Hung, Judy W and Voisine, Pierre and Dagenais, Francois and Gillinov, A. Marc and Thourani, Vinod and Argenziano, Michael and Gammie, James S and Mack, Michael and Demers, Philippe and Atluri, Pavan and Rose, Eric A and O’Sullivan, Karen and Williams, Deborah L and Bagiella, Emilia and Michler, Robert E and Weisel, Richard D and Miller, Marissa A and Geller, Nancy L and Taddei-Peters, Wendy C and Smith, Peter K and Moquete, Ellen and Overbey, Jessica R and Kron, Irving L and O’Gara, Patrick T and Acker, Michael A and CTSN
The New England journal of medicine, ISSN 0028-4793, 01/2016, Volume 374, Issue 4, pp. 344 - 353
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Recurrence | Heart Valve Prosthesis Implantation | Mitral Valve Insufficiency - surgery | Ventricular Function, Left | Humans | Mitral Valve - surgery | Hospitalization | Mitral Valve Insufficiency - mortality | Ventricular Remodeling | Heart Ventricles - physiopathology | Treatment Failure | Reoperation - statistics & numerical data | Heart Ventricles - anatomy & histology | Mitral Valve Insufficiency - complications | Quality of Life | Heart Failure - etiology | Treatment outcome | Care and treatment | Usage | Echocardiography | Analysis | Mitral valve repair | Mitral valve insufficiency | Heart | Ischemia | Heart surgery | Surgery | Regurgitation | Cardiovascular disease | Ventricle | Heart diseases | Survival | Patients | Clinical outcomes | Index Medicus | Abridged Index Medicus
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