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Nucleic Acids Research, ISSN 0305-1048, 10/2014, Volume 43, Issue 1, pp. 629 - 644
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 02/2014, Volume 50, Issue 14, pp. 1704 - 1707
We report here on the screening of a fragment library against a G-quadruplex element in the human c-MYC promoter. The ten fragment hits had significant... 
Models, Molecular | G-Quadruplexes | Proto-Oncogene Proteins c-myc - genetics | Promoter Regions, Genetic - genetics | Computer Simulation | Humans
Journal Article
Chemical Communications, ISSN 1359-7345, 02/2014, Volume 50, Issue 14, pp. 1704 - 1707
We report here on the screening of a fragment library against a G-quadruplex element in the human c-MYC promoter. The ten fragment hits had significant... 
KIT ONCOGENE | TELOMERIC DNA | HUMAN GENOME | FLUORESCENT INTERCALATOR | SMALL-MOLECULE | TRANSCRIPTION | GENE-EXPRESSION | PROMOTER | SELECTIVITY | CHEMISTRY, MULTIDISCIPLINARY | DISCOVERY | Index Medicus
Journal Article
by Clark, Andrew G and Eisen, Michael B and Smith, Douglas R and Bergman, Casey M and Oliver, Brian and Markow, Therese A and Kaufman, Thomas C and Kellis, Manolis and Gelbart, William and Iyer, Venky N and Pollard, Daniel A and Sackton, Timothy B and Larracuente, Amanda M and Singh, Nadia D and Abad, Jose P and Abt, Dawn N and Adryan, Boris and Aguade, Montserrat and Akashi, Hiroshi and Anderson, Wyatt W and Aquadro, Charles F and Ardell, David H and Arguello, Roman and Artieri, Carlo G and Barbash, Daniel A and Barker, Daniel and Barsanti, Paolo and Batterham, Phil and Batzoglou, Serafim and Begun, Dave and Bhutkar, Arjun and Blanco, Enrico and Bosak, Stephanie A and Bradley, Robert K and Brand, Adrianne D and Brent, Michael R and Brooks, Angela N and Brown, Randall H and Butlin, Roger K and Caggese, Corrado and Calvi, Brian R and Bernardo De Carvalho, A and Caspi, Anat and Castrezana, Sergio and Celniker, Susan E and Chang, Jean L and Chapple, Charles and Chatterji, Sourav and Chinwalla, Asif and Civetta, Alberto and Clifton, Sandra W and Comeron, Josep M and Costello, James C and Coyne, Jerry A and Daub, Jennifer and David, Robert G and Delcher, Arthur L and Delehaunty, Kim and Do, Chuong B and Ebling, Heather and Edwards, Kevin and Eickbush, Thomas and Evans, Jay D and Filipski, Alan and Findeiß, Sven and Freyhult, Eva and Fulton, Lucinda and Fulton, Robert and Garcia, Ana C. L and Gardiner, Anastasia and Garfield, David A and Garvin, Barry E and Gibson, Greg and Gilbert, Don and Gnerre, Sante and Godfrey, Jennifer and Good, Robert and Gotea, Valer and Gravely, Brenton and Greenberg, Anthony J and Griffiths-Jones, Sam and Gross, Samuel and Guigo, Roderic and Gustafson, Erik A and Haerty, Wilfried and Hahn, Matthew W and Halligan, Daniel L and Halpern, Aaron L and Halter, Gillian M and Han, Mira V and Heger, Andreas and Hillier, LaDeana and Hinrichs, Angie S and Holmes, Ian and Hoskins, Roger A and Hubisz, Melissa J and Hultmark, Dan and Huntley, Melanie A and Jaffe, David B and Jagadeeshan, Santosh and ... and Drosophila 12 Genomes Consor and Broad Inst Whole Genome Ass and Broad Inst Genome Sequencing and Drosophila 12 Genomes Consortium and Medicinska fakulteten and Umeå centrum för molekylär patogenes (UCMP) (Medicinska fakulteten) and Umeå universitet
Nature, ISSN 0028-0836, 11/2007, Volume 450, Issue 7167, pp. 203 - 218
Journal Article
by Gerstein, Hertzel C and Bosch, Jackie and Dagenais, Gilles R and Díaz, Rafael and Jung, Hyejung and Maggioni, Aldo P and Pogue, Janice and Probstfield, Jeffrey and Ramachandran, Ambady and Riddle, Matthew C and Rydén, Lars E and Yusuf, Salim and Richardson, L and Diaz, R and Johnston, P and Vige, R and Birkeland, K and Budaj, A and Cardona, E and Chazova, I and Commerford, P and Danilova, L and Davies, M and Fernando, R and Fodor, G and Gilbert, R and Gomis, R and Hâncu, N and Hanefeld, M and Hildebrandt, P and Kacerovsky-Bielesz, G and Keltai, M and Kim, J.H and Krum, H and Kültürsay, H and Lanas, F and Lewis, B.S and Lonn, E and López-Jaramillo, P and Marin-Neto, J and Marre, M and McKelvie, R and McQueen, M and Mendoza, I and Morillo, C and Pan, C and Pīrāgs, V and Profozic, V and Ratner, R and Richardson, L and Rosenstock, J and Spinas, G.A and Sreenan, S and Stoel, I and Syvänne, M and Yale, J.F and Avezum, A and Bahit, M.C and Bogaty, P and Bordeleau, L and Chacόn, C and Corson, M and Harper, W.L and Halon, D and Magloire, P and Mann, J and Pavlova, V and Punthakee, Z and Silva, J and Tsang, B and Yakubovich, N and Abdallah, A and Ahmad, S and Chandra, J and Chandra, R and Cukierman-Yaffee, T and Dyal, L and Joldersma, L and MacRae, L and MacRae, S and Malik, S and Mead, A and Pasha, F and Pazmino-Canizares, J and Pohl, K and Sakalas, A and Tyrwhitt, J and Ahuad Guerrero, R and Alebuena, A and Alvarez, N and Alzogaray, M and Amuchastegui, M and Andres, M and Angos, M and Baglivo, H and Barbieri, M and Bassi, F and Bello, F and Bono, J and Bustamante Labarta, M and ... and The ORIGIN Trial Investigators and ORIGIN Trial Investigators and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Centrum för klinisk forskning, Västerås
The New England Journal of Medicine, ISSN 0028-4793, 07/2012, Volume 367, Issue 4, pp. 319 - 328
In this study with a 2-by-2 factorial design, patients with cardiovascular risk factors and dysglycemia or type 2 diabetes received insulin glargine or... 
DIABETES-MELLITUS | MEDICINE, GENERAL & INTERNAL | GLYCEMIC CONTROL | THERAPY | GLARGINE | GLUCOSE CONTROL | DISEASE | RISK | PEOPLE | ENDOTHELIAL FUNCTION | BETA-CELL FUNCTION | Follow-Up Studies | Cardiovascular Diseases - prevention & control | Cholesterol - blood | Humans | Middle Aged | Male | Incidence | Glucose Intolerance - drug therapy | Cardiovascular Diseases - epidemiology | Female | Drug Therapy, Combination | Hypoglycemia - chemically induced | Diabetes Mellitus, Type 2 - complications | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Fasting | Blood Glucose - analysis | Double-Blind Method | Proportional Hazards Models | Hospitalization | Glucose Intolerance - complications | Insulin, Long-Acting - adverse effects | Insulin Glargine | Insulin, Long-Acting - therapeutic use | Intention to Treat Analysis | Triglycerides - blood | Fatty Acids, Omega-3 - therapeutic use | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Type 2 diabetes | Complications and side effects | Care and treatment | Insulin glargine | Patient outcomes | Causes of | Cardiovascular diseases | Risk factors | Myocardial infarction | Fees & charges | Cerebral infarction | Medical research | Stroke | Heart attacks | Statistical analysis | Diabetes mellitus | Glucose | Hypoglycemia | Fatty acids | Insulin | Glucose tolerance | Insulin resistance | Microvasculature | Diabetes | Diabetes mellitus (non-insulin dependent) | Heart diseases | Drug dosages | Index Medicus | Abridged Index Medicus | Cardiovascular Diseases | Insulin, Long-Acting | Blood Glucose | Triglycerides | Glucose Intolerance | Cholesterol | Life Sciences | Hypoglycemic Agents | Diabetes Mellitus, Type 2 | Fatty Acids, Omega-3 | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article