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Lancet, The, ISSN 0140-6736, 2014, Volume 383, Issue 9911, pp. 60 - 68
Summary Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to LDL receptors, leading to their degradation. Genetics studies have shown that... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | DENSITY-LIPOPROTEIN CHOLESTEROL | DOUBLE-STRANDED-RNA | PLASMA-CHOLESTEROL | METAANALYSIS | CARDIOVASCULAR-DISEASE | MONOCLONAL-ANTIBODY | HYPERCHOLESTEROLEMIA | STATINS | AMG 145 | ATORVASTATIN | Single-Blind Method | Serine Endopeptidases - biosynthesis | Humans | Middle Aged | RNA, Small Interfering - pharmacology | RNA, Small Interfering - adverse effects | Cholesterol, LDL - drug effects | Male | Healthy Volunteers | Proprotein Convertases - genetics | Dose-Response Relationship, Drug | Proprotein Convertases - biosynthesis | RNA Interference | Serine Endopeptidases - blood | Serine Endopeptidases - genetics | Adult | Cholesterol, LDL - blood | Female | Proprotein Convertases - blood | RNA, Small Interfering - administration & dosage | Genetic Therapy - adverse effects | Genetic Therapy - methods | Proprotein Convertase 9 | Enzymes | Research | Gene mutations | Properties | Gene expression | Identification and classification | Medical research | RNA | Low density lipoproteins | Anticholesteremic agents | Clinical trials | Aluminum compounds | Coronary heart disease | Cholesterol | Hypercholesterolemia | Analysis | Medicine, Experimental | Product development | Trans fatty acids | Blood proteins | Studies | Heart | Nanoparticles | Plasma | Nutrition research | Cardiovascular disease | Lipids | Mutation | Drug dosages | Statins | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2013, Volume 369, Issue 9, pp. 819 - 829
Journal Article
Cancer Discovery, ISSN 2159-8274, 04/2013, Volume 3, Issue 4, pp. 406 - 417
Journal Article
Circulation, ISSN 0009-7322, 12/2007, Volume 116, Issue 23, pp. 2678 - 2686
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 12/1991, Volume 50, Issue 6, pp. 695 - 701
The disposition of acetaminophen after oral administration was investigated in adults with cystic fibrosis (n = 5) and in age-matched healthy control subjects... 
Analysis of Variance | Administration, Oral | Cystic Fibrosis - metabolism | Humans | Acetaminophen - administration & dosage | Adult | Female | Male | Acetaminophen - pharmacokinetics | Chromatography, High Pressure Liquid
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2015, Volume 21, Issue 5, pp. 492 - 497
Journal Article
Journal Article
Molecular Therapy, ISSN 1525-0016, 08/2012, Volume 20, Issue 8, pp. 1582 - 1589
Journal Article
Journal Article
Silence, ISSN 1758-907X, 07/2010, Volume 1, Issue 1, pp. 14 - 14
Fire and Mello initiated the current explosion of interest in RNA interference (RNAi) biology with their seminal work in Caenorhabditis elegans. These... 
Physiological aspects | Genetic aspects | Genetic engineering | Messenger RNA | Drosophila | Analysis
Journal Article