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Pharmacological Research, ISSN 1043-6618, 2019, p. 104170
The past two decades of intense research have revealed a key role of the sphingolipid molecule sphingosine 1-phosphate (S1P) in regulating multiple... 
S1P receptor modulators | Inflammation | Fingolimod | Autoimmune diseases
Journal Article
Molecules, ISSN 1420-3049, 2018, Volume 23, Issue 1, p. 158
Peptide drug discovery may play a key role in the identification of novel medicinal agents. Here, we present the development of novel small peptides able to... 
Mesangial cells | Prostaglandin E2 | Inhibitors | Peptides | Secreted phospholipase A2 | Phospholipase | Phospholipase A2 | Rodents | Drug discovery | inhibitors | peptides | prostaglandin E2 | mesangial cells | secreted phospholipase A2
Journal Article
Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 01/2014, Volume 114, Issue 1, pp. 44 - 49
Journal Article
Science, ISSN 0036-8075, 6/2010, Volume 328, Issue 5983, pp. 1290 - 1294
During sepsis, activation of phagocytes leads to the overproduction of proinflammatory cytokines, causing systemic inflammation. Despite substantial... 
Bacteriophages | Cytokines | Antibiotics | REPORTS | Neutrophils | Small interfering RNA | Sepsis | Septic shock | Inflammation | Macrophages | Vehicles | ACTIVATION | THERAPY | CECAL LIGATION | INFLAMMATORY RESPONSES | MULTIDISCIPLINARY SCIENCES | RECEPTOR | FC-GAMMA-RI | SPHINGOSINE KINASE | CA2+ SIGNALS | MODULATION | PUNCTURE | Up-Regulation | Humans | Middle Aged | Endotoxins | Male | NF-kappa B - metabolism | Shock, Septic - immunology | Lipopolysaccharides - immunology | Young Adult | Sepsis - drug therapy | RNA Interference | Aged, 80 and over | Adult | Female | Bacterial Proteins - immunology | Macrophages - immunology | Cytokines - blood | Sepsis - immunology | Cytokines - metabolism | Neutrophils - enzymology | Signal Transduction | Enzyme Inhibitors - pharmacology | Macrophages, Peritoneal - enzymology | Neutrophils - immunology | Macrophages, Peritoneal - immunology | Phosphotransferases (Alcohol Group Acceptor) - genetics | Peritonitis - immunology | Enzyme Inhibitors - therapeutic use | Macrophages - enzymology | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Protein Kinase C-delta - metabolism | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Peritonitis - enzymology | Animals | Sepsis - enzymology | Adolescent | Aged | Mice | Shock, Septic - enzymology | Enzyme Activation | Lipoproteins - immunology | Phagocytes | Physiological aspects | Diagnosis | Research | Risk factors | Enzymes | Molecular biology | Immune system
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 04/2008, Volume 28, Issue 8, pp. 2608 - 2625
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 06/2016, Volume 6, Issue 1, p. 27594
Serum levels of the lipid mediator sphingosine-1-phosphate (S1P) are reduced in septic patients and are inversely associated with disease severity. We show... 
SPHINGOSINE 1-PHOSPHATE RECEPTORS | BETA-COMMON RECEPTOR | AKT ACTIVATION | KINASE TYPE-2 | MULTIDISCIPLINARY SCIENCES | IN-VIVO | ENDOTHELIAL-CELLS | SEPTIC SHOCK | INJURY | ORGAN DYSFUNCTION | HIGH-DENSITY-LIPOPROTEIN
Journal Article