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The New England journal of medicine, ISSN 1533-4406, 09/2017, Volume 377, Issue 12, pp. 1119 - 1131
Patients with myocardial infarction and a high-sensitivity CRP level of 2 mg or more per liter were assigned to one of three canakinumab doses or placebo. The... 
no | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Secondary Prevention | Infection - etiology | Incidence | Dose-Response Relationship, Drug | Anti-Inflammatory Agents - adverse effects | C-Reactive Protein - metabolism | Lipids - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Anti-Inflammatory Agents - administration & dosage | Female | Neutropenia - chemically induced | Interleukin-1beta - antagonists & inhibitors | Stroke - prevention & control | Atherosclerosis - drug therapy | Double-Blind Method | Interleukin-1beta - immunology | Atherosclerosis - blood | Myocardial Infarction - drug therapy | Antibodies, Monoclonal - administration & dosage | Aged | Myocardial Infarction - prevention & control | Myocardial infarction | Cerebral infarction | Stroke | Heart attacks | C-reactive protein | Cytokines | Clinical trials | Cardiovascular disease | Innate immunity | Inflammation | Angina | Angina pectoris | Thrombosis | Cholesterol | Disease prevention | Proteins | Arteriosclerosis | Atherosclerosis | Cardiovascular diseases | Health risk assessment | Drug therapy | Drug dosages | Index Medicus | Abridged Index Medicus | Klinisk medicin | Clinical Medicine
Journal Article
by Evangelou, Evangelos and Warren, Helen R and Mosen-Ansorena, David and Mifsud, Borbala and Pazoki, Raha and Gao, He and Ntritsos, Georgios and Dimou, Niki and Cabrera, Claudia P and Karaman, Ibrahim and Ng, Fu Liang and Evangelou, Marina and Witkowska, Katarzyna and Tzanis, Evan and Hellwege, Jacklyn N and Giri, Ayush and Velez Edwards, Digna R and Sun, Yan V and Cho, Kelly and Gaziano, J. Michael and Wilson, Peter W. F and Tsao, Philip S and Kovesdy, Csaba P and Esko, Tonu and Mägi, Reedik and Milani, Lili and Almgren, Peter and Boutin, Thibaud and Debette, Stéphanie and Ding, Jun and Giulianini, Franco and Holliday, Elizabeth G and Jackson, Anne U and Li-Gao, Ruifang and Lin, Wei-Yu and Luan, Jian’an and Mangino, Massimo and Oldmeadow, Christopher and Prins, Bram Peter and Qian, Yong and Sargurupremraj, Muralidharan and Shah, Nabi and Surendran, Praveen and Thériault, Sébastien and Verweij, Niek and Willems, Sara M and Zhao, Jing-Hua and Amouyel, Philippe and Connell, John and de Mutsert, Renée and Doney, Alex S. F and Farrall, Martin and Menni, Cristina and Morris, Andrew D and Noordam, Raymond and Paré, Guillaume and Poulter, Neil R and Shields, Denis C and Stanton, Alice and Thom, Simon and Abecasis, Gonçalo and Amin, Najaf and Arking, Dan E and Ayers, Kristin L and Barbieri, Caterina M and Batini, Chiara and Bis, Joshua C and Blake, Tineka and Bochud, Murielle and Boehnke, Michael and Boerwinkle, Eric and Boomsma, Dorret I and Bottinger, Erwin P and Braund, Peter S and Brumat, Marco and Campbell, Archie and Campbell, Harry and Chakravarti, Aravinda and Chambers, John C and Chauhan, Ganesh and Ciullo, Marina and Cocca, Massimiliano and Collins, Francis and Cordell, Heather J and Davies, Gail and de Borst, Martin H and de Geus, Eco J and Deary, Ian J and Deelen, Joris and Del Greco M, Fabiola and Demirkale, Cumhur Yusuf and Dörr, Marcus and Ehret, Georg B and Elosua, Roberto and Enroth, Stefan and Erzurumluoglu, A. Mesut and Ferreira, Teresa and Frånberg, Mattias and Franco, Oscar H and Gandin, Ilaria and ... and the Million Veteran Program and Million Vet Program and Million Veteran Program and The Million Veteran Program
Nature genetics, ISSN 1546-1718, 09/2018, Volume 50, Issue 10, pp. 1412 - 1425
Journal Article
by Warren, Helen R and Evangelou, Evangelos and Cabrera, Claudia P and Gao, He and Ren, Meixia and Mifsud, Borbala and Ntalla, Ioanna and Surendran, Praveen and Liu, Chunyu and Cook, James P and Kraja, Aldi T and Drenos, Fotios and Loh, Marie and Verweij, Niek and Marten, Jonathan and Karaman, Ibrahim and Lepe, Marcelo P Segura and O'Reilly, Paul F and Knight, Joanne and Snieder, Harold and Kato, Norihiro and He, Jiang and Tai, E Shyong and Said, M Abdullah and Porteous, David and Alver, Maris and Poulter, Neil and Farrall, Martin and Gansevoort, Ron T and Padmanabhan, Sandosh and Mägi, Reedik and Stanton, Alice and Connell, John and Bakker, Stephan J L and Metspalu, Andres and Shields, Denis C and Thom, Simon and Brown, Morris and Sever, Peter and Esko, Tõnu and Hayward, Caroline and van der Harst, Pim and Saleheen, Danish and Chowdhury, Rajiv and Chambers, John C and Chasman, Daniel I and Chakravarti, Aravinda and Newton-Cheh, Christopher and Lindgren, Cecilia M and Levy, Daniel and Kooner, Jaspal S and Keavney, Bernard and Tomaszewski, Maciej and Samani, Nilesh J and Howson, Joanna M M and Tobin, Martin D and Munroe, Patricia B and Ehret, Georg B and Wain, Louise V and The CHD Exome+ Consortium and The International Consortium of Blood Pressure (ICBP) 1000G Analyses and The International Genomics of Blood Pressure (iGEN-BP) Consortium and The UK Biobank CardioMetabolic Consortium BP working group and The Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium and The GoT2DGenes Consortium and The ExomeBP Consortium and The T2D-GENES Consortium and CHARGE BP Exome Consortium and UK Biobank CardioMetab Consortium and GoT2D Genes Consortium and Understanding Soc Sci Grp and Lifelines Cohort Study and Int Consortium Blood Pressure ICBP and BIOS Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-GENES Consortium and iGEN-BP Consortium and International Consortium of Blood Pressure (ICBP) 1000G Analyses and Understanding Society Scientific group and CHD Exome+ Consortium and Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium and International Genomics of Blood Pressure (iGEN-BP) Consortium and UK Biobank CardioMetabolic Consortium BP working group and GoT2DGenes Consortium
Nature genetics, ISSN 1546-1718, 01/2017, Volume 49, Issue 3, pp. 403 - 415
Journal Article
by van der Harst, Pim and van Setten, Jessica and Verweij, Niek and Vogler, Georg and Franke, Lude and Maurano, Matthew T and Wang, Xinchen and Mateo Leach, Irene and Eijgelsheim, Mark and Sotoodehnia, Nona and Hayward, Caroline and Sorice, Rossella and Meirelles, Osorio and Lyytikäinen, Leo-Pekka and Polašek, Ozren and Tanaka, Toshiko and Arking, Dan E and Ulivi, Sheila and Trompet, Stella and Müller-Nurasyid, Martina and Smith, Albert V and Dörr, Marcus and Kerr, Kathleen F and Magnani, Jared W and Del Greco M, Fabiola and Zhang, Weihua and Nolte, Ilja M and Silva, Claudia T and Padmanabhan, Sandosh and Tragante, Vinicius and Esko, Tõnu and Abecasis, Gonçalo R and Adriaens, Michiel E and Andersen, Karl and Barnett, Phil and Bis, Joshua C and Bodmer, Rolf and Buckley, Brendan M and Campbell, Harry and Cannon, Megan V and Chakravarti, Aravinda and Chen, Lin Y and Delitala, Alessandro and Devereux, Richard B and Doevendans, Pieter A and Dominiczak, Anna F and Ferrucci, Luigi and Ford, Ian and Gieger, Christian and Harris, Tamara B and Haugen, Eric and Heinig, Matthias and Hernandez, Dena G and Hillege, Hans L and Hirschhorn, Joel N and Hofman, Albert and Hubner, Norbert and Hwang, Shih-Jen and Iorio, Annamaria and Kähönen, Mika and Kellis, Manolis and Kolcic, Ivana and Kooner, Ishminder K and Kooner, Jaspal S and Kors, Jan A and Lakatta, Edward G and Lage, Kasper and Launer, Lenore J and Levy, Daniel and Lundby, Alicia and Macfarlane, Peter W and May, Dalit and Meitinger, Thomas and Metspalu, Andres and Nappo, Stefania and Naitza, Silvia and Neph, Shane and Nord, Alex S and Nutile, Teresa and Okin, Peter M and Olsen, Jesper V and Oostra, Ben A and Penninger, Josef M and Pennacchio, Len A and Pers, Tune H and Perz, Siegfried and Peters, Annette and Pinto, Yigal M and Pfeufer, Arne and Pilia, Maria Grazia and Pramstaller, Peter P and Prins, Bram P and Raitakari, Olli T and Raychaudhuri, Soumya and Rice, Ken M and Rossin, Elizabeth J and Rotter, Jerome I and Schafer, Sebastian and Schlessinger, David and Schmidt, Carsten O and ...
Journal of the American College of Cardiology, ISSN 0735-1097, 2016, Volume 68, Issue 13, pp. 1435 - 1448
Journal Article
by Munroe, Patricia B and Rice, Kenneth M and Johnson, Anew D and Verwoert, Germaine C and Hwang, Shih-Jen and Pihur, Vasyl and Vollenweider, Peter and Teumer, Alexander and Launer, Lenore and Zhao, Jing Hua and Aulchenko, Yurii and Parsa, Afshin and Arora, Pankaj and Zhang, Feng and Lucas, Gavin and Hicks, Anew A and Jackson, Anne U and Wild, Sarah H and Rudan, Igor and Milaneschi, Yuri and Fox, Ervin R and Kumari, Meena and Go, Min Jin and Vinay, D. G and Alexander, Myriam and Tabara, Yasuharu and Whincup, Peter H and Liu, Yongmei and Kuusisto, Johanna and Tayo, Bamidele and Seielstad, Mark and Sim, Xueling and Nguyen, Khanh-Dung Hoang and Wu, Ying and Gaunt, Tom R and Onland-Moret, N. Charlotte and Org, Elin and Hardy, Rebecca and Dahgam, Santosh and Kuznetsova, Tatiana and Uiterwaal, Cuno S. P. M and Adeyemo, Adebowale and Palmas, Walter and Campbell, Harry and Tomaszewski, Maciej and Tzoulaki, Ioanna and Palmer, Nicholette D and Aspelund, Thor and Garcia, Melissa and Chang, Yen-Pei C and O'Connell, Jeffrey R and Steinle, Nanette I and Arking, Dan E and Hernandez, Dena and Najjar, Samer and McArdle, Wendy L and Hadley, David and Brown, Morris J and Day, Ian N. M and Lawlor, Debbie A and Beilby, John P and Lawrence, Robert W and Clarke, Robert and Hopewell, Jemma C and isbach, Albert W and Young, J. Hunter and Kähönen, Mika and Lee, Nanette R and Olden, Matthias and Bolton, Judith A. Hoffman and Mooser, Vincent and Chaturvedi, Nish and Frayling, Timothy M and Jafar, Tazeen H and Kulkarni, Smita R and Bornstein, Stefan R and Grässler, Jürgen and Voight, Benjamin F and Howard, Philip and Taylor, Anew and Guarrera, Simonetta and Emilsson, Valur and Plump, Anew and Khaw, Kay-Tee and Weder, Alan B and Hunt, Steven C and Sun, Yan V and Bergman, Richard N and Collins, Francis S and Bonnycastle, Lori L and Scott, Laura J and Stringham, Heather M and Perola, Markus and Staessen, Jan A and Wang, Thomas J and Burton, Paul R and Artigas, Maria Soler and Dong, Yanbin and Snieder, Harold and Wang, Xiaoling and ... and The International Consortium for Blood Pressure Genome-Wide Association Studies and CHARGE-HF Consortium and EchoGen Consortium and KidneyGen Consortium and CARDIoGRAM Consortium and Int Consortium Blood Pressure Geno and CKDGen Consortium and International Consortium for Blood Pressure Genome-Wide Association Studies and EchoGen consortium and CHARGE-HF consortium and CARDIoGRAM consortium
Nature (London), ISSN 1476-4687, 09/2011, Volume 478, Issue 7367, pp. 103 - 109
Journal Article