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Cancer Science, ISSN 1347-9032, 12/2017, Volume 108, Issue 12, pp. 2470 - 2477
Journal Article
Anticancer Research, ISSN 0250-7005, 09/2018, Volume 38, Issue 9, p. 5057
Background/Aim: High expression of the Bcl-2-interacting cell death suppressor (BIS), an anti-apoptotic protein, in various human cancers is linked to a poor... 
CRISPR | Cell culture | Phenotypes | Wound healing | Mesenchyme | Bcl-2 protein | Invasiveness | Lung cancer | Non-small cell lung carcinoma | mRNA | E-cadherin | Gelatinase A | Proteins | Signal transduction | N-Cadherin | Depletion | Cell death | Synaptotagmin | Cell migration | Apoptosis
Journal Article
Anticancer Research, ISSN 0250-7005, 11/2018, Volume 38, Issue 11, p. 6309
Background/Aim: Patients with advanced non-small cell lung cancer (NSCLC) frequently face a dismal prognosis because of lack of curative therapies. We,... 
Cell proliferation | Lung cancer | Cyclin-dependent kinases | MiRNA | Non-small cell lung carcinoma | Gene expression | Kinases | Ribonucleic acid--RNA | Cyclin-dependent kinase | Cyclin-dependent kinase 2 | Cell growth | MicroRNAs | Combinatorial analysis | Cancer
Journal Article
Anticancer Research, ISSN 0250-7005, 08/2018, Volume 38, Issue 8, p. 4525
Background/Aim: High expression of the Bcl-2-interacting cell death suppressor (BIS), an anti-apoptotic protein, in various human cancers is linked to a poor... 
CRISPR | Cell culture | NF-κB protein | Phenotypes | Wound healing | Mesenchyme | Bcl-2 protein | Invasiveness | Lung cancer | Non-small cell lung carcinoma | mRNA | E-cadherin | Gelatinase A | Proteins | Signal transduction | N-Cadherin | Cell death | Synaptotagmin | Cell migration | Apoptosis
Journal Article
Journal Article
Journal of Experimental and Clinical Cancer Research, ISSN 1756-9966, 01/2018, Volume 37, Issue 1, pp. 4 - 12
Background: Pancreatic stellate cells (PSCs), a major component of the tumor microenvironment in pancreatic cancer, play roles in cancer progression as well as... 
Tumor microenvironment | Microchannel plate | EMT | Pancreatic cancer | Cancer-Stroma co-culture | CANCER CELLS | DUCTAL ADENOCARCINOMA | NAB-PACLITAXEL | MicroChannel plate | CULTURE | FIBROBLASTS | EPITHELIAL-MESENCHYMAL TRANSITION | IN-VITRO | MICROENVIRONMENT | ONCOLOGY | COLORECTAL-CANCER | PROGRESSION | Cell culture | Usage | Development and progression | Models | Research | Drug therapy | Methods | Microfluidics
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, p. e73345
Intrinsic drug resistance of pancreatic ductal adenocarcinoma (PDAC) warrants studies using models that are more clinically relevant for identifying novel... 
CELLS | MICROENVIRONMENT | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | SIZE | GROWTH | PENETRATION | 3-D | SCAFFOLDS | CANCER | CULTURE | Pancreatic Neoplasms - drug therapy | Antinematodal Agents - pharmacokinetics | Drug Screening Assays, Antitumor - instrumentation | Humans | Pancreatic Neoplasms - pathology | Spheroids, Cellular - pathology | Cell Line, Tumor | Spheroids, Cellular - drug effects | Antinematodal Agents - pharmacology | Equipment Design | Drugs | Fibronectins | Product/Service Evaluations | Dimethylpolysiloxane | Drug resistance | Antineoplastic agents | Transforming growth factors | Antimitotic agents | MicroRNA | Pancreatic cancer | Collagen | Stem cells | Diagnosis | Drug therapy | Cancer | Adenocarcinoma | Collagen (type I) | Silicone resins | Chemoresistance | Drug development | Drug screening | Polydimethyl siloxanes | Cancer therapies | Fibronectin | Anticancer properties | Necrosis | Proteins | Laminin | Polyethylene glycol | Cell cycle | Extracellular matrix | Polydimethylsiloxane | Growth factors | Biomedical engineering | Quantitative analysis | Medical research | Evaluation | Connective tissue growth factor | Gene expression | Spheroids | Medicine | Screening | Chemotherapy | MicroRNAs | Cell lines | Plates (structural members) | In vivo methods and tests | Viability | Three dimensional models | Acid phosphatase | Methods | Tumors
Journal Article
Journal Article
by Hwang, HJ and Oh, MS and Lee, DW and Kuh, HJ
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, ISSN 1756-9966, 06/2019, Volume 38, Issue 1, pp. 258 - 258
BackgroundPancreatic ductal adenocarcinoma (PDAC) is a stroma-rich carcinoma, and pancreatic stellate cells (PSCs) are a major component of this dense stroma.... 
MIGRATION | Cancer invasion | Tumor microenvironment | CULTURE | FIBROBLASTS | Pancreatic stellate cell | MICROENVIRONMENT | ONCOLOGY | PATHWAY | Paclitaxel | EXTRACELLULAR-MATRIX | 3D co-culture | Tumor spheroids | Matrix remodeling | PLASTICITY | Pancreatic cancer | Collagen | Fibroblasts | Extracellular matrix | Metastasis | Drug resistance | Growth factors | Spheroids | Tumors | Cell adhesion & migration
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 5789 - 5789
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 2114 - 2114
Journal Article
RSC Advances, 01/2018, Volume 8, Issue 9, pp. 4494 - 4502
Tumor spheroids are multicellular, three-dimensional (3D) cell culture models closely mimicking the microenvironments of human tumors in vivo, thereby... 
Proteins | Antibodies | Three dimensional models | Spheroids | Fragility
Journal Article