European Journal of Cancer, ISSN 0959-8049, 12/2018, Volume 105, pp. 61 - 70
Subcutaneous trastuzumab (H SC) is a valuable alternative to the intravenous formulation. This study assessed H SC safety and tolerability in human epidermal...
Early/locally advanced breast cancer | Subcutaneous trastuzumab | Cardiotoxicity | Safety | HER2 | ADJUVANT CHEMOTHERAPY | ONCOLOGY | PLUS | Antimitotic agents | Care and treatment | Safety and security measures | Analysis | Oncology, Experimental | Breast cancer | Research | Antineoplastic agents | Cancer | Slopes | Therapy | Intravenous administration | Injection | Congestive heart failure | Disease control | Patients | ErbB-2 protein | Heart rate | Chemotherapy | Epidermal growth factor | Anaphylaxis | Anthracycline | Pleuropericarditis | Ventricle | Taxanes | Growth factors | Trastuzumab | Ejection
Early/locally advanced breast cancer | Subcutaneous trastuzumab | Cardiotoxicity | Safety | HER2 | ADJUVANT CHEMOTHERAPY | ONCOLOGY | PLUS | Antimitotic agents | Care and treatment | Safety and security measures | Analysis | Oncology, Experimental | Breast cancer | Research | Antineoplastic agents | Cancer | Slopes | Therapy | Intravenous administration | Injection | Congestive heart failure | Disease control | Patients | ErbB-2 protein | Heart rate | Chemotherapy | Epidermal growth factor | Anaphylaxis | Anthracycline | Pleuropericarditis | Ventricle | Taxanes | Growth factors | Trastuzumab | Ejection
Journal Article
Hepatology, ISSN 0270-9139, 04/2015, Volume 61, Issue 4, pp. 1145 - 1153
Limited data are available about the efficacy of antiviral treatment in hepatitis C virus (HCV)–associated mixed cryoglobulinemia (MC), especially concerning...
B-CELLS | HEPATITIS-C VIRUS | ANTIVIRAL THERAPY | II CRYOGLOBULINEMIA | SUSTAINED RESPONSE | RITUXIMAB | INFECTED PATIENTS | VASCULITIS | LIVER-DISEASE | GASTROENTEROLOGY & HEPATOLOGY | INTERFERON THERAPY | Recombinant Proteins - therapeutic use | Prospective Studies | Hepatitis C - drug therapy | Antiviral Agents - therapeutic use | Humans | Middle Aged | Ribavirin - therapeutic use | Interferon-alpha - therapeutic use | Male | Cryoglobulinemia - virology | Cryoglobulinemia - complications | Polyethylene Glycols - therapeutic use | Time Factors | Female | Hepatitis C - complications | Drug Therapy, Combination | Hepacivirus | Cohort Studies | Hepatitis
B-CELLS | HEPATITIS-C VIRUS | ANTIVIRAL THERAPY | II CRYOGLOBULINEMIA | SUSTAINED RESPONSE | RITUXIMAB | INFECTED PATIENTS | VASCULITIS | LIVER-DISEASE | GASTROENTEROLOGY & HEPATOLOGY | INTERFERON THERAPY | Recombinant Proteins - therapeutic use | Prospective Studies | Hepatitis C - drug therapy | Antiviral Agents - therapeutic use | Humans | Middle Aged | Ribavirin - therapeutic use | Interferon-alpha - therapeutic use | Male | Cryoglobulinemia - virology | Cryoglobulinemia - complications | Polyethylene Glycols - therapeutic use | Time Factors | Female | Hepatitis C - complications | Drug Therapy, Combination | Hepacivirus | Cohort Studies | Hepatitis
Journal Article
Neurology, ISSN 0028-3878, 07/2014, Volume 83, Issue 3, pp. 215 - 220
OBJECTIVE:To assess in a noninterventional setting the prevalence and severity of fatigue in patients with Parkinson disease (PD). METHODS:This was a...
DEPRESSION | IMPACT | NONMOTOR SYMPTOMS | DISORDERS | PHYSICAL-ACTIVITY | QUALITY-OF-LIFE | CLINICAL NEUROLOGY | Severity of Illness Index | Depression - physiopathology | Depression - epidemiology | Prevalence | Age Factors | Cross-Sectional Studies | Humans | Middle Aged | Male | Parkinson Disease - physiopathology | Fatigue - epidemiology | Sleep Wake Disorders - epidemiology | Time Factors | Aged, 80 and over | Fatigue - physiopathology | Parkinson Disease - epidemiology | Adult | Female | Italy - epidemiology | Aged | Parkinson Disease - classification | Sleep Wake Disorders - physiopathology
DEPRESSION | IMPACT | NONMOTOR SYMPTOMS | DISORDERS | PHYSICAL-ACTIVITY | QUALITY-OF-LIFE | CLINICAL NEUROLOGY | Severity of Illness Index | Depression - physiopathology | Depression - epidemiology | Prevalence | Age Factors | Cross-Sectional Studies | Humans | Middle Aged | Male | Parkinson Disease - physiopathology | Fatigue - epidemiology | Sleep Wake Disorders - epidemiology | Time Factors | Aged, 80 and over | Fatigue - physiopathology | Parkinson Disease - epidemiology | Adult | Female | Italy - epidemiology | Aged | Parkinson Disease - classification | Sleep Wake Disorders - physiopathology
Journal Article
Gut, ISSN 0017-5749, 02/2013, Volume 62, Issue 2, pp. 290 - 298
Objective Treatment with peginterferon α-2a (PegIFN) for 48 weeks is the standard of care for selected HBeAg-negative patients chronically infected with...
Recombinant Proteins - therapeutic use | Humans | Middle Aged | Polyethylene Glycols - adverse effects | Male | Alanine Transaminase - blood | Recombinant Proteins - adverse effects | Polyethylene Glycols - therapeutic use | Lamivudine - adverse effects | Hepatitis B, Chronic - genetics | Time Factors | Lamivudine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Female | Hepatitis B, Chronic - blood | Drug Therapy, Combination | Hepatitis B virus - immunology | Antiviral Agents - therapeutic use | Anti-HIV Agents - adverse effects | Interferon-alpha - therapeutic use | Treatment Outcome | DNA, Viral - blood | Hepatitis B, Chronic - drug therapy | Antiviral Agents - adverse effects | Hepatitis B virus - genetics | Interferon-alpha - adverse effects | Hepatitis B e Antigens - blood
Recombinant Proteins - therapeutic use | Humans | Middle Aged | Polyethylene Glycols - adverse effects | Male | Alanine Transaminase - blood | Recombinant Proteins - adverse effects | Polyethylene Glycols - therapeutic use | Lamivudine - adverse effects | Hepatitis B, Chronic - genetics | Time Factors | Lamivudine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Female | Hepatitis B, Chronic - blood | Drug Therapy, Combination | Hepatitis B virus - immunology | Antiviral Agents - therapeutic use | Anti-HIV Agents - adverse effects | Interferon-alpha - therapeutic use | Treatment Outcome | DNA, Viral - blood | Hepatitis B, Chronic - drug therapy | Antiviral Agents - adverse effects | Hepatitis B virus - genetics | Interferon-alpha - adverse effects | Hepatitis B e Antigens - blood
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 56, Issue 5, pp. 1006 - 1011
Background & Aims It was recently demonstrated that none of the hepatitis B e antigen (HBeAg)-negative patients without any serum hepatitis B surface antigen...
Gastroenterology and Hepatology | Immunomodulator | HBV genotype | Nucleos(t)ide analogues | Quantitative HBsAg | HBV therapy | Peginterferon | LAMIVUDINE | ENTECAVIR | SUSTAINED RESPONSE | GENOTYPE | CHRONIC HEPATITIS-B | GASTROENTEROLOGY & HEPATOLOGY | Recombinant Proteins - therapeutic use | Predictive Value of Tests | Antiviral Agents - therapeutic use | Humans | Middle Aged | Interferon-alpha - therapeutic use | Genotype | Male | Treatment Outcome | Biomarkers - blood | Hepatitis B - blood | Withholding Treatment | Polyethylene Glycols - therapeutic use | Hepatitis B Surface Antigens - blood | DNA, Viral - blood | Dose-Response Relationship, Drug | Time Factors | Hepatitis B - drug therapy | Hepatitis B virus - genetics | Adult | Female | Retrospective Studies | Antigen-antibody reactions | Hepatitis | Antigens | Care and treatment | Heterocyclic compounds | DNA | Interferon | Hepatitis B
Gastroenterology and Hepatology | Immunomodulator | HBV genotype | Nucleos(t)ide analogues | Quantitative HBsAg | HBV therapy | Peginterferon | LAMIVUDINE | ENTECAVIR | SUSTAINED RESPONSE | GENOTYPE | CHRONIC HEPATITIS-B | GASTROENTEROLOGY & HEPATOLOGY | Recombinant Proteins - therapeutic use | Predictive Value of Tests | Antiviral Agents - therapeutic use | Humans | Middle Aged | Interferon-alpha - therapeutic use | Genotype | Male | Treatment Outcome | Biomarkers - blood | Hepatitis B - blood | Withholding Treatment | Polyethylene Glycols - therapeutic use | Hepatitis B Surface Antigens - blood | DNA, Viral - blood | Dose-Response Relationship, Drug | Time Factors | Hepatitis B - drug therapy | Hepatitis B virus - genetics | Adult | Female | Retrospective Studies | Antigen-antibody reactions | Hepatitis | Antigens | Care and treatment | Heterocyclic compounds | DNA | Interferon | Hepatitis B
Journal Article
GUT, ISSN 0017-5749, 02/2013, Volume 62, Issue 2, pp. 290 - 298
Objective Treatment with peginterferon alpha-2a (PegIFN) for 48 weeks is the standard of care for selected HBeAg-negative patients chronically infected with...
E-ANTIGEN | LAMIVUDINE | ENTECAVIR | INTERFERON-ALPHA | SUSTAINED RESPONSE | RETREATMENT | GASTROENTEROLOGY & HEPATOLOGY | EPIDEMIOLOGY
E-ANTIGEN | LAMIVUDINE | ENTECAVIR | INTERFERON-ALPHA | SUSTAINED RESPONSE | RETREATMENT | GASTROENTEROLOGY & HEPATOLOGY | EPIDEMIOLOGY
Journal Article
Neuroendocrinology, ISSN 0028-3835, 05/2018, Volume 106, Issue 4, pp. 307 - 311
Background: We previously presented data of this multicentric, phase II study showing that everolimus plus octreotide long-acting repeatable (LAR) for advanced...
Original Paper | Octreotide long-acting repeatable | Neuroendocrine tumor | Everolimus | LUNG | RADIANT-2 | BIOLOGY | ENDOCRINOLOGY & METABOLISM | SUNITINIB | AKT | PHASE-3 | NEUROSCIENCES | Humans | Middle Aged | Kaplan-Meier Estimate | Octreotide - adverse effects | Male | Treatment Outcome | Everolimus - administration & dosage | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Everolimus - adverse effects | Neuroendocrine Tumors - mortality | Neuroendocrine Tumors - drug therapy | Adult | Female | Aged | Octreotide - administration & dosage | Delayed-Action Preparations | Antimitotic agents | Care and treatment | Antineoplastic agents | Analysis | Tumors
Original Paper | Octreotide long-acting repeatable | Neuroendocrine tumor | Everolimus | LUNG | RADIANT-2 | BIOLOGY | ENDOCRINOLOGY & METABOLISM | SUNITINIB | AKT | PHASE-3 | NEUROSCIENCES | Humans | Middle Aged | Kaplan-Meier Estimate | Octreotide - adverse effects | Male | Treatment Outcome | Everolimus - administration & dosage | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Everolimus - adverse effects | Neuroendocrine Tumors - mortality | Neuroendocrine Tumors - drug therapy | Adult | Female | Aged | Octreotide - administration & dosage | Delayed-Action Preparations | Antimitotic agents | Care and treatment | Antineoplastic agents | Analysis | Tumors
Journal Article
Hepatology, ISSN 0270-9139, 04/2015, Volume 61, Issue 4, pp. 1145 - 1153
Journal Article
Gut, ISSN 0017-5749, 02/2013, Volume 62, Issue 2, p. 290
Objective Treatment with peginterferon α-2a (PegIFN) for 48 weeks is the standard of care for selected HBeAg-negative patients chronically infected with...
Care and treatment | Hepatitis associated antigen | Dosage and administration | Peginterferon alfa-2a | Research | Hepatitis B | Genotype & phenotype | Hepatitis | Liver diseases | Interferon | Infections | Clinical medicine | Liver cirrhosis | Patients | Deoxyribonucleic acid--DNA
Care and treatment | Hepatitis associated antigen | Dosage and administration | Peginterferon alfa-2a | Research | Hepatitis B | Genotype & phenotype | Hepatitis | Liver diseases | Interferon | Infections | Clinical medicine | Liver cirrhosis | Patients | Deoxyribonucleic acid--DNA
Journal Article
BMJ Open Gastroenterology, ISSN 2054-4774, 05/2016, Volume 3, Issue 1, p. e000092
IntroductionA study has been developed to assess the use and effectiveness of budesonide MMX for mild-to-moderate active ulcerative colitis (UC) in routine...
Inflammatory bowel disease | Studies | Questionnaires | Product development | Joint surgery | Colon | Endoscopy | Patient satisfaction | Quality of life | Life Sciences
Inflammatory bowel disease | Studies | Questionnaires | Product development | Joint surgery | Colon | Endoscopy | Patient satisfaction | Quality of life | Life Sciences
Journal Article
Radiotherapy and Oncology, ISSN 0167-8140, 2014, Volume 113, Issue 2, pp. 260 - 266
Abstract Background and purpose To compare volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT) plans for treatment of...
Hematology, Oncology and Palliative Medicine | Normal tissue sparing | Intensity modulated radiation therapy | Target coverage | Volumetric modulated arc therapy | Dosimetric comparison | Unresectable paranasal sinus cancer | HEAD | VMAT | IMRT | TUMORS | NECK-CANCER | NASOPHARYNGEAL CARCINOMA | ONCOLOGY | NASAL CAVITY | PARANASAL SINUS CANCER | UPDATE | HELICAL TOMOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Radiotherapy Dosage | Radiometry - methods | Paranasal Sinus Neoplasms - radiotherapy | Radiotherapy Planning, Computer-Assisted - methods | Humans | Radiotherapy, Intensity-Modulated - methods | Comparative analysis | Radiotherapy | Radiation | Cancer
Hematology, Oncology and Palliative Medicine | Normal tissue sparing | Intensity modulated radiation therapy | Target coverage | Volumetric modulated arc therapy | Dosimetric comparison | Unresectable paranasal sinus cancer | HEAD | VMAT | IMRT | TUMORS | NECK-CANCER | NASOPHARYNGEAL CARCINOMA | ONCOLOGY | NASAL CAVITY | PARANASAL SINUS CANCER | UPDATE | HELICAL TOMOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Radiotherapy Dosage | Radiometry - methods | Paranasal Sinus Neoplasms - radiotherapy | Radiotherapy Planning, Computer-Assisted - methods | Humans | Radiotherapy, Intensity-Modulated - methods | Comparative analysis | Radiotherapy | Radiation | Cancer
Journal Article
European Journal of Gastroenterology & Hepatology, ISSN 0954-691X, 04/2014, Volume 26, Issue 4, pp. 388 - 395
BACKGROUNDThis large prospective multicentre cohort study aimed to improve knowledge of therapy for chronic hepatitis C (CHC) in real clinical practice....
Italy | comorbidities | peginterferon a | special populations | sustained virological response | PLUS RIBAVIRIN | PEGINTERFERON ALPHA-2A | GASTROENTEROLOGY & HEPATOLOGY | peginterferon | Recombinant Proteins - therapeutic use | Recurrence | Prospective Studies | Humans | Middle Aged | Hepacivirus - genetics | Polyethylene Glycols - adverse effects | Male | RNA, Viral - blood | Recombinant Proteins - adverse effects | Polyethylene Glycols - therapeutic use | Viral Load | Young Adult | Time Factors | Aged, 80 and over | Adult | Female | Hepatitis C, Chronic - epidemiology | Drug Therapy, Combination | Hepacivirus - drug effects | Antiviral Agents - therapeutic use | Comorbidity | Ribavirin - therapeutic use | Interferon-alpha - therapeutic use | Genotype | Treatment Outcome | Hepatitis C, Chronic - diagnosis | Hepatitis C, Chronic - drug therapy | Remission Induction | Ribavirin - adverse effects | Antiviral Agents - adverse effects | Adolescent | Italy - epidemiology | Aged | Interferon-alpha - adverse effects
Italy | comorbidities | peginterferon a | special populations | sustained virological response | PLUS RIBAVIRIN | PEGINTERFERON ALPHA-2A | GASTROENTEROLOGY & HEPATOLOGY | peginterferon | Recombinant Proteins - therapeutic use | Recurrence | Prospective Studies | Humans | Middle Aged | Hepacivirus - genetics | Polyethylene Glycols - adverse effects | Male | RNA, Viral - blood | Recombinant Proteins - adverse effects | Polyethylene Glycols - therapeutic use | Viral Load | Young Adult | Time Factors | Aged, 80 and over | Adult | Female | Hepatitis C, Chronic - epidemiology | Drug Therapy, Combination | Hepacivirus - drug effects | Antiviral Agents - therapeutic use | Comorbidity | Ribavirin - therapeutic use | Interferon-alpha - therapeutic use | Genotype | Treatment Outcome | Hepatitis C, Chronic - diagnosis | Hepatitis C, Chronic - drug therapy | Remission Induction | Ribavirin - adverse effects | Antiviral Agents - adverse effects | Adolescent | Italy - epidemiology | Aged | Interferon-alpha - adverse effects
Journal Article
Liver International, ISSN 1478-3223, 01/2015, Volume 35, Issue 1, pp. 120 - 129
Background & Aims Hepatitis C virus (HCV) genotype 3 (G3) is common among HIV/HCV co‐infected individuals and associated with moderate sustained virological...
HIV infections | ribavirin | peginterferon alfa‐2a | hepatitis C | Peginterferon alfa-2a | Hepatitis C | Ribavirin | WEIGHT-BASED RIBAVIRIN | CHRONIC HEPATITIS-C | INCREASING BURDEN | HUMAN-IMMUNODEFICIENCY-VIRUS | NATURAL-HISTORY | LIVER-DISEASE | HCV INFECTION | HIV-INFECTED PATIENTS | peginterferon alfa-2a | PEGYLATED INTERFERON | ALPHA-2A PLUS RIBAVIRIN | GASTROENTEROLOGY & HEPATOLOGY | Recombinant Proteins - therapeutic use | Prospective Studies | Hepatitis C - drug therapy | Coinfection - drug therapy | Humans | Ribavirin - therapeutic use | Interferon-alpha - therapeutic use | Hepacivirus - genetics | Genotype | Hepatitis C - genetics | RNA, Viral - blood | Polyethylene Glycols - therapeutic use | Drug Therapy, Combination - methods | HIV Infections - complications | HIV Infections - drug therapy | Hepatitis C - complications | Italy | Odds Ratio
HIV infections | ribavirin | peginterferon alfa‐2a | hepatitis C | Peginterferon alfa-2a | Hepatitis C | Ribavirin | WEIGHT-BASED RIBAVIRIN | CHRONIC HEPATITIS-C | INCREASING BURDEN | HUMAN-IMMUNODEFICIENCY-VIRUS | NATURAL-HISTORY | LIVER-DISEASE | HCV INFECTION | HIV-INFECTED PATIENTS | peginterferon alfa-2a | PEGYLATED INTERFERON | ALPHA-2A PLUS RIBAVIRIN | GASTROENTEROLOGY & HEPATOLOGY | Recombinant Proteins - therapeutic use | Prospective Studies | Hepatitis C - drug therapy | Coinfection - drug therapy | Humans | Ribavirin - therapeutic use | Interferon-alpha - therapeutic use | Hepacivirus - genetics | Genotype | Hepatitis C - genetics | RNA, Viral - blood | Polyethylene Glycols - therapeutic use | Drug Therapy, Combination - methods | HIV Infections - complications | HIV Infections - drug therapy | Hepatitis C - complications | Italy | Odds Ratio
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 05/2014, Volume 9, Issue 5, pp. 733 - 737
The aim of the present study was to evaluate the efficacy and tolerability of vandetanib plus gemcitabine (V/G) compared with gemcitabine alone in elderly...
Non–small-cell lung cancer | Vandetanib | Gemcitabine | Elderly | Non-small-cell lung cancer | METAANALYSIS | KINASE INHIBITOR | DOCETAXEL | CHEMOTHERAPY | TRIAL | THERAPY | ONCOLOGY | RESPIRATORY SYSTEM | 2ND-LINE TREATMENT | DOUBLE-BLIND | Lung Neoplasms - drug therapy | Piperidines - administration & dosage | Double-Blind Method | Deoxycytidine - administration & dosage | Humans | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Survival Rate | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Piperidines - adverse effects | Quinazolines - adverse effects | Aged, 80 and over | Deoxycytidine - adverse effects | Female | Quinazolines - administration & dosage | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Deoxycytidine - analogs & derivatives | Placebos - administration & dosage
Non–small-cell lung cancer | Vandetanib | Gemcitabine | Elderly | Non-small-cell lung cancer | METAANALYSIS | KINASE INHIBITOR | DOCETAXEL | CHEMOTHERAPY | TRIAL | THERAPY | ONCOLOGY | RESPIRATORY SYSTEM | 2ND-LINE TREATMENT | DOUBLE-BLIND | Lung Neoplasms - drug therapy | Piperidines - administration & dosage | Double-Blind Method | Deoxycytidine - administration & dosage | Humans | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Survival Rate | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Piperidines - adverse effects | Quinazolines - adverse effects | Aged, 80 and over | Deoxycytidine - adverse effects | Female | Quinazolines - administration & dosage | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Deoxycytidine - analogs & derivatives | Placebos - administration & dosage
Journal Article
Antiviral Therapy, ISSN 1359-6535, 2015, Volume 20, Issue 1, pp. 39 - 48
Background: Until recently, recommendations for HCV treatment in HIV-coinfected patients have been combination therapy with pegylated interferon (PEG-IFN) and...
INFECTIOUS DISEASES | WEIGHT-BASED RIBAVIRIN | VIRUS-INFECTION | ANTIVIRAL THERAPY | COMBINATION THERAPY | CHRONIC HEPATITIS-C | ITPA GENE POLYMORPHISMS | SUSTAINED VIROLOGICAL RESPONSE | VIROLOGY | PEGINTERFERON ALPHA-2A | ALPHA-2A PLUS RIBAVIRIN | PHARMACOLOGY & PHARMACY | INFECTED PATIENTS | Hepatitis C, Chronic - pathology | Coinfection | Cell Count | Humans | Middle Aged | Hepatitis C, Chronic - virology | Polyethylene Glycols - adverse effects | Anemia - pathology | Male | Recombinant Proteins - adverse effects | HIV-1 - physiology | HIV Infections - pathology | Ribavirin - administration & dosage | Neutropenia - pathology | Adult | Female | Hepacivirus - physiology | Neutropenia - chemically induced | Hepacivirus - drug effects | HIV-1 - drug effects | HIV Infections - virology | Anemia - chemically induced | Thrombocytopenia - chemically induced | Hepatitis C, Chronic - drug therapy | Thrombocytopenia - pathology | Antiviral Agents - administration & dosage | Polyethylene Glycols - administration & dosage | Recombinant Proteins - administration & dosage | Interferon-alpha - administration & dosage | Ribavirin - adverse effects | Antiviral Agents - adverse effects | HIV Infections - drug therapy | Interferon-alpha - adverse effects | Viral Load - drug effects
INFECTIOUS DISEASES | WEIGHT-BASED RIBAVIRIN | VIRUS-INFECTION | ANTIVIRAL THERAPY | COMBINATION THERAPY | CHRONIC HEPATITIS-C | ITPA GENE POLYMORPHISMS | SUSTAINED VIROLOGICAL RESPONSE | VIROLOGY | PEGINTERFERON ALPHA-2A | ALPHA-2A PLUS RIBAVIRIN | PHARMACOLOGY & PHARMACY | INFECTED PATIENTS | Hepatitis C, Chronic - pathology | Coinfection | Cell Count | Humans | Middle Aged | Hepatitis C, Chronic - virology | Polyethylene Glycols - adverse effects | Anemia - pathology | Male | Recombinant Proteins - adverse effects | HIV-1 - physiology | HIV Infections - pathology | Ribavirin - administration & dosage | Neutropenia - pathology | Adult | Female | Hepacivirus - physiology | Neutropenia - chemically induced | Hepacivirus - drug effects | HIV-1 - drug effects | HIV Infections - virology | Anemia - chemically induced | Thrombocytopenia - chemically induced | Hepatitis C, Chronic - drug therapy | Thrombocytopenia - pathology | Antiviral Agents - administration & dosage | Polyethylene Glycols - administration & dosage | Recombinant Proteins - administration & dosage | Interferon-alpha - administration & dosage | Ribavirin - adverse effects | Antiviral Agents - adverse effects | HIV Infections - drug therapy | Interferon-alpha - adverse effects | Viral Load - drug effects
Journal Article
Journal of Women's Health, ISSN 1540-9996, 02/2015, Volume 24, Issue 2, pp. 159 - 164
Background: This was a post-hoc analysis of the Optimized Pegylated interferons Efficacy and anti-Retroviral Approach (OPERA) study, originally designed to...
Original Articles | VIRUS-INFECTION | CHRONIC HEPATITIS-C | LIVER FIBROSIS | NATURAL-HISTORY | OBSTETRICS & GYNECOLOGY | MEDICINE, GENERAL & INTERNAL | HEPATOCELLULAR-CARCINOMA | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | INSULIN-RESISTANCE | ESTROGEN | HCV | WOMEN'S STUDIES | MENOPAUSE | PROGRESSION | Recombinant Proteins - therapeutic use | Coinfection - drug therapy | Humans | Middle Aged | Hepatitis C, Chronic - virology | Male | RNA, Viral - blood | Hepatitis C, Chronic - complications | Polyethylene Glycols - therapeutic use | Viral Load | Time Factors | Ribavirin - administration & dosage | Aging | Adult | Female | Drug Therapy, Combination | Hepacivirus - drug effects | Hepacivirus - isolation & purification | Antiviral Agents - therapeutic use | HIV-1 - drug effects | HIV Infections - virology | Ribavirin - therapeutic use | Interferon-alpha - therapeutic use | RNA, Viral - analysis | Logistic Models | Treatment Outcome | Hepatitis C, Chronic - drug therapy | Antiviral Agents - administration & dosage | Polyethylene Glycols - administration & dosage | Recombinant Proteins - administration & dosage | Interferon-alpha - administration & dosage | HIV Infections - complications | Glucose - metabolism | HIV Infections - drug therapy | Italy
Original Articles | VIRUS-INFECTION | CHRONIC HEPATITIS-C | LIVER FIBROSIS | NATURAL-HISTORY | OBSTETRICS & GYNECOLOGY | MEDICINE, GENERAL & INTERNAL | HEPATOCELLULAR-CARCINOMA | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | INSULIN-RESISTANCE | ESTROGEN | HCV | WOMEN'S STUDIES | MENOPAUSE | PROGRESSION | Recombinant Proteins - therapeutic use | Coinfection - drug therapy | Humans | Middle Aged | Hepatitis C, Chronic - virology | Male | RNA, Viral - blood | Hepatitis C, Chronic - complications | Polyethylene Glycols - therapeutic use | Viral Load | Time Factors | Ribavirin - administration & dosage | Aging | Adult | Female | Drug Therapy, Combination | Hepacivirus - drug effects | Hepacivirus - isolation & purification | Antiviral Agents - therapeutic use | HIV-1 - drug effects | HIV Infections - virology | Ribavirin - therapeutic use | Interferon-alpha - therapeutic use | RNA, Viral - analysis | Logistic Models | Treatment Outcome | Hepatitis C, Chronic - drug therapy | Antiviral Agents - administration & dosage | Polyethylene Glycols - administration & dosage | Recombinant Proteins - administration & dosage | Interferon-alpha - administration & dosage | HIV Infections - complications | Glucose - metabolism | HIV Infections - drug therapy | Italy
Journal Article
Antiviral Therapy, ISSN 1359-6535, 2014, Volume 19, Issue 8, pp. 735 - 745
Background: The Optimized Pegylated interferons Efficacy and anti-Retroviral Approach (OPERA) study aimed to assess the efficacy and safety profile of...
ALPHA-2A | INFECTIOUS DISEASES | WEIGHT-BASED RIBAVIRIN | TELAPREVIR | COMBINATION THERAPY | CHRONIC HEPATITIS-C | HUMAN-IMMUNODEFICIENCY-VIRUS | SUSTAINED VIROLOGICAL RESPONSE | TRIAL
ALPHA-2A | INFECTIOUS DISEASES | WEIGHT-BASED RIBAVIRIN | TELAPREVIR | COMBINATION THERAPY | CHRONIC HEPATITIS-C | HUMAN-IMMUNODEFICIENCY-VIRUS | SUSTAINED VIROLOGICAL RESPONSE | TRIAL