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Neuron, ISSN 0896-6273, 2010, Volume 65, Issue 5, pp. 597 - 611
To investigate the role of microRNAs in regulating oligodendrocyte (OL) differentiation and myelination, we utilized transgenic mice in which microRNA... 
DEVBIO | MOLNEURO | TRANSCRIPTION FACTORS | NERVOUS-SYSTEM | GLIAL PROGENITOR-CELL | PROTEIN | CYCLE EXIT | NEURONS | GROWTH-FACTOR | IDENTIFICATION | MICRORNA EXPRESSION | LINEAGE | NEUROSCIENCES | Central Nervous System - metabolism | MicroRNAs - metabolism | Green Fluorescent Proteins - genetics | S100 Proteins - genetics | Oligodendroglia - drug effects | Basic Helix-Loop-Helix Transcription Factors - metabolism | Animals, Newborn | Basic Helix-Loop-Helix Transcription Factors - genetics | Receptor, Platelet-Derived Growth Factor alpha - metabolism | S100 Calcium Binding Protein beta Subunit | Oligonucleotide Array Sequence Analysis - methods | Rats | Mice, Transgenic | Oligodendrocyte Transcription Factor 2 | Myelin Proteins - genetics | Rats, Sprague-Dawley | Nerve Growth Factors - genetics | Mice | MicroRNAs - genetics | Myelin Proteins - metabolism | SOXD Transcription Factors - genetics | Optic Nerve - metabolism | Age Factors | SOXD Transcription Factors - metabolism | Gene Expression Regulation, Developmental - genetics | Sciatic Nerve - growth & development | Myelin Sheath - metabolism | Central Nervous System - growth & development | DNA-Binding Proteins - metabolism | Sciatic Nerve - metabolism | Oligodendroglia - physiology | Transfection | DEAD-box RNA Helicases - metabolism | Cell Differentiation - physiology | Optic Nerve - growth & development | Brain - cytology | 2',3'-Cyclic-Nucleotide Phosphodiesterases - genetics | Ribonuclease III - genetics | Ribonuclease III - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Profiling - methods | Transcription Factors - genetics | 2',3'-Cyclic-Nucleotide Phosphodiesterases - metabolism | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | DEAD-box RNA Helicases - genetics | Animals | Cell Differentiation - drug effects | Receptor, Platelet-Derived Growth Factor alpha - genetics | Stem Cells - drug effects | Stem Cells - physiology | Proteins | Genotype & phenotype | Gene expression | Experiments | Rodents | Cell cycle | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 06/2013, Volume 15, Issue 6, pp. 614 - 624
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 4, pp. e18088 - e18088
Differentiation of oligodendrocyte progenitor cells (OPCs) into mature oligodendrocytes requires extensive changes in gene expression, which are partly... 
HISTONE DEACETYLASE ACTIVITY | MESSENGER-RNA | MYELINATION | MULTIDISCIPLINARY SCIENCES | FUNCTIONAL GENOMIC ANALYSIS | CLUSTERING METHODS | REMYELINATION | CENTRAL-NERVOUS-SYSTEM | PROGENITOR DIFFERENTIATION | TRANSCRIPTION FACTOR | EXPRESSION | Oligodendroglia - metabolism | Gene Regulatory Networks - genetics | Oligonucleotide Array Sequence Analysis | Cells, Cultured | Rats | Gene Regulatory Networks - physiology | Reverse Transcriptase Polymerase Chain Reaction | Rats, Sprague-Dawley | Cell Differentiation - genetics | Animals | Chromatin Immunoprecipitation | Mice | Oligodendroglia - cytology | Cell Differentiation - physiology | Algorithms | RNA | Lysine | Analysis | Genes | Physiological aspects | Histones | Genetic transcription | DNA binding proteins | Histone deacetylase | Regulations | Cell culture | Neurosciences | Transcription factors | Gene regulation | Genomes | Biology | Glial stem cells | Datasets | Proteins | Engineering | Annotations | Oligodendrocytes | Cell cycle | Reaction kinetics | Post-translation | Clusters | Trichostatin A | Mathematical models | Lipid metabolism | RNA processing | Bioinformatics | Biomedical engineering | Overlaying | Enzymes | Data analysis | EGR-1 protein | Gene clusters | Gene expression | Clustering | Metabolism | Medicine | Gene silencing | Myelination | Ribonucleic acids | Cells (biology) | Epigenetics | Kinetics | Differentiation | Index Medicus | Waves
Journal Article
Molecular and Cellular Neuroscience, ISSN 1044-7431, 05/2012, Volume 50, Issue 1, pp. 45 - 57
Hypothyroidism is a well-described cause of hypomyelination. In addition, thyroid hormone (T3) has recently been shown to enhance remyelination in various... 
Thyroid hormone | BTEB1 | Oligodendrocyte | Cuprizone | Myelin | KLF9 | SPINAL-CORD DEMYELINATION | THYROID-HORMONE ACTION | ELEMENT-BINDING PROTEIN-1 | MAGNETIC-RESONANCE SPECTROSCOPY | NEUROSCIENCES | KRUPPEL-LIKE FACTOR-9 | IN-VIVO | CONGENITAL HYPOTHYROIDISM | CENTRAL-NERVOUS-SYSTEM | EXPERIMENTAL HYPOTHYROIDISM | RAT-BRAIN | Myelin Sheath - physiology | Oligonucleotide Array Sequence Analysis | Myelin Sheath - drug effects | Rats | Mice, Knockout | Transcription Factors - metabolism | Cell Differentiation - genetics | Animals | Oligodendroglia - physiology | Cuprizone - pharmacology | Gene Expression Regulation, Developmental | Kruppel-Like Transcription Factors - metabolism | Mice | RNA, Small Interfering | Oligodendroglia - cytology | Kruppel-Like Transcription Factors - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | Triiodothyronine - pharmacology | Platelet-derived growth factor | Analysis | Genes | Albumin | Fibroblast growth factors | DNA binding proteins | Genetic transcription | Thyroid hormones | Sulfates | Myelin proteins | Index Medicus | Animal models | Multiple sclerosis | Transcription factors | Demyelinating diseases | Central nervous system | Nervous system | Hairless | Hypothyroidism | Glial stem cells | Regeneration | Myelination | Demyelination | Oligodendrocytes | genomics | Helix-loop-helix proteins | Triiodothyronine | Differentiation
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2007, Volume 27, Issue 23, pp. 6185 - 6196
Journal Article
Developmental Cell, ISSN 1534-5807, 07/2015, Volume 34, Issue 2, pp. 152 - 167
Journal Article
Cell, ISSN 0092-8674, 12/2018, Volume 175, Issue 7, pp. 1811 - 1826.e21
Nervous system function depends on proper myelination for insulation and critical trophic support for axons. Myelination is tightly regulated spatially and... 
stress response | temporal and regional specificity | oligodendrocyte | myelination | CNS | transcription factor EB | PUMA | programmed cell death | AXONS | SURVIVAL | REGULATOR | BIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DYNAMICS | NEURONS | DIFFERENTIATION | GLIA | LINEAGE | PLASTICITY | CELL BIOLOGY | Medical colleges | Biochemistry | Gene expression | Neurophysiology | Apoptosis
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 08/2008, Volume 28, Issue 33, pp. 8294 - 8305
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2007, Volume 27, Issue 23, pp. 6185 - 6196
The intracellular molecular mechanism that controls the timing of oligodendrocyte differentiation remains unknown. Temple and Raff (1986) previously showed... 
Journal Article
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