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Cell Stem Cell, ISSN 1934-5909, 07/2019, Volume 25, Issue 1, pp. 1 - 2
Direct lineage conversion offers a fast and simple method to study mature neurons , but its utility for investigating neurodevelopment has remained unclear. In... 
HISTONE ACETYLATION | KINASE | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
Neuron, ISSN 0896-6273, 12/2014, Volume 84, Issue 6, pp. 1213 - 1225
Journal Article
Cell Stem Cell, ISSN 1934-5909, 08/2015, Volume 17, Issue 2, pp. 127 - 129
Direct lineage conversion could provide a rich source of somatic cell types for translational medicine, but concerns over the use of transgenic reprogramming... 
DEFINED FACTORS | CONVERSION | MOUSE | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cellular Reprogramming - drug effects | Small Molecule Libraries - pharmacology | Animals | Humans | Male | Neurons - cytology | Fibroblasts - cytology | Fibroblasts - pathology | Alzheimer Disease - pathology | Index Medicus
Journal Article
ISSN 0896-6273, 12/2014, Volume 84, Issue 6, p. 1213
  Expanded GGGGCC (G4C2) nucleotide repeats within theC9ORF72gene are the most common genetic mutation associated with both amyotrophic lateral sclerosis (ALS)... 
Proteins | Survival analysis | Hypotheses | Neurotoxicity | Microscopy | Neurodegeneration | Neurons | Rodents | Amyotrophic lateral sclerosis | Alzheimers disease | Gene expression | Patients
Journal Article
Neuron, ISSN 0896-6273, 12/2014, Volume 84, Issue 6, pp. 1213 - 1225
Expanded GGGGCC (G4C2) nucleotide repeats within the C9ORF72 gene are the most common genetic mutation associated with both amyotrophic lateral sclerosis (ALS)... 
Journal Article
Cell Stem Cell, ISSN 1934-5909, 11/2009, Volume 5, Issue 5, pp. 491 - 503
Journal Article
Nature Medicine, ISSN 1078-8956, 03/2018, Volume 24, Issue 3, pp. 313 - 325
An intronic GGGGCC repeat expansion in C9ORF72 is the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but the... 
MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | REPEAT EXPANSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FRONTOTEMPORAL DEMENTIA | ALS | TRAFFICKING | AMYOTROPHIC-LATERAL-SCLEROSIS | CELL BIOLOGY | IN-VIVO | HUMAN FIBROBLASTS | HEXANUCLEOTIDE REPEAT | GGGGCC REPEAT | C9orf72 Protein - genetics | Frontotemporal Dementia - genetics | Haploinsufficiency - genetics | rab5 GTP-Binding Proteins - genetics | Introns - genetics | Endosomes - genetics | DNA Repeat Expansion - genetics | Gene Expression Regulation - genetics | Amyotrophic Lateral Sclerosis - genetics | Humans | Nerve Degeneration - physiopathology | Nerve Degeneration - genetics | Motor Neurons - pathology | Motor Neurons - metabolism | Amyotrophic Lateral Sclerosis - pathology | Animals | Mutation | Disease Models, Animal | Frontotemporal Dementia - pathology | Care and treatment | Development and progression | Amyotrophic lateral sclerosis | Genetic aspects | Open reading frames | Gene expression | Frontotemporal dementia | Health aspects | Motor neurons | Animal models | Cell survival | Neurons | Trafficking | Motor ability | Glutamic acid receptors | Neuromodulation | Modulators | Sclerosis | Haploinsufficiency | Proteins | Receptors | Neurotoxicity | Neurodegeneration | Rodents | Excitotoxicity | Dementia disorders | Evolution | Expansion | Endosomes | Index Medicus
Journal Article
Nature Genetics, ISSN 1061-4036, 04/2018, Volume 50, Issue 4, pp. 603 - 612
Journal Article
Development (Cambridge, England), ISSN 0950-1991, 11/2018, Volume 145, Issue 22, p. dev168617
Advances in stemcell science allowthe production of different cell types in vitro either through the recapitulation of developmental processes, often termed... 
Directed differentiation | Motor neuron | Reprogramming | Lineage conversion | Embryonic stem cells | iPS cell | PATHWAYS | MOUSE | DIRECT CONVERSION | DEVELOPMENTAL BIOLOGY | INDUCTION | PLURIPOTENT | MAPS | HUMAN FIBROBLASTS | Index Medicus
Journal Article