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Journal of Clinical Investigation, ISSN 0021-9738, 01/2008, Volume 118, Issue 1, pp. 29 - 39
Adrenomedullin (AM) is a peptide involved both in the pathogenesis of cardiovascular diseases and in circulatory homeostasis. The high-affinity AM receptor is... 
MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVITY-MODIFYING PROTEINS | ENDOGENOUS ADRENOMEDULLIN | CARDIAC-HYPERTROPHY | ENDOTHELIAL-CELLS | GENE-EXPRESSION | SMOOTH-MUSCLE-CELLS | ANGIOTENSIN-II | KNOCKOUT MICE | INDUCED AIRWAY HYPERRESPONSIVENESS | TRANSGENIC MICE | Capillary Permeability - physiology | Embryonic Stem Cells - metabolism | Edema - genetics | Receptors, Calcitonin - metabolism | Tight Junctions - genetics | Humans | Male | Receptors, Calcitonin - genetics | Calcitonin Receptor-Like Protein | Cardiovascular Diseases - pathology | Cardiovascular Diseases - genetics | Receptors, Peptide - genetics | Arteries - metabolism | Embryo Loss - metabolism | Embryo Loss - pathology | Female | Embryo Loss - genetics | Intracellular Signaling Peptides and Proteins - genetics | Receptor Activity-Modifying Protein 2 | Tight Junctions - metabolism | Cardiovascular Diseases - metabolism | Membrane Proteins - genetics | Cells, Cultured | Receptors, Adrenomedullin | Adrenomedullin - metabolism | Arteries - pathology | Adrenomedullin - genetics | Mice, Knockout | Pregnancy | Edema - metabolism | Neovascularization, Physiologic - physiology | Membrane Proteins - biosynthesis | Animals | Endothelium, Vascular - metabolism | Homeostasis - physiology | Embryonic Stem Cells - pathology | Endothelium, Vascular - pathology | Receptor Activity-Modifying Proteins | Mice | Edema - pathology | Tight Junctions - pathology | Receptors, Peptide - metabolism | Proteins | Physiological aspects | Research | Peptides | Cardiovascular diseases | Index Medicus | Abridged Index Medicus
Journal Article
Endocrinology, ISSN 0013-7227, 05/2017, Volume 158, Issue 5, pp. 1194 - 1206
Journal Article
Endocrinology, ISSN 0013-7227, 05/2017, Volume 158, Issue 5, pp. 1359 - 1372
Neointimal hyperplasia is the primary lesion underlying atherosclerosis and restenosis after coronary intervention. We previously described the essential... 
PROGENITOR CELLS | ARTERIAL INJURY | VASCULAR INJURY | ACCELERATES REENDOTHELIALIZATION | NAD(P)H OXIDASE | HYPOTENSIVE PEPTIDE | ENDOCRINOLOGY & METABOLISM | ACTIVATED-RECEPTOR-GAMMA | NEOINTIMAL HYPERPLASIA | NECROSIS-FACTOR-ALPHA | SMOOTH-MUSCLE-CELLS | Femoral Artery - pathology | Vascular System Injuries - genetics | Humans | Mice, Inbred C57BL | Cells, Cultured | Male | Signal Transduction - genetics | Vascular System Injuries - prevention & control | Neointima - metabolism | Adrenomedullin - genetics | Mice, Knockout | Femoral Artery - injuries | Neointima - genetics | Animals | Adrenomedullin - physiology | Neointima - pathology | Femoral Artery - metabolism | Receptor Activity-Modifying Protein 2 - genetics | Cytoprotection - genetics | Mice | Endothelial Cells - physiology | Receptor Activity-Modifying Protein 2 - physiology | Cell proliferation | Oxidative stress | Leukocyte migration | Syngeneic grafts | Hyperplasia | Bone marrow transplantation | Adrenomedullin | Smooth muscle | Macrophages | Receptor activity modifying proteins | Angiogenesis | Vascular diseases | Clonal deletion | Rodents | Atherosclerosis | Bone marrow | Deletion | Injuries | Medical treatment | Muscles | Blood vessels | Transplants | Inflammation | Endothelial cells | Restenosis | Arteriosclerosis | Stem cells | Cells (biology) | Infiltration | Bone | Cell migration | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, pp. e87667 - e87667
Various bioactive peptides have been implicated in the homeostasis of organs and tissues. Adrenomedullin (AM) is a peptide with various bioactivities.... 
UNFOLDED PROTEIN RESPONSE | HYPOTENSIVE PEPTIDE | GENE | INDUCED APOPTOSIS | PLASMA-LEVELS | MULTIDISCIPLINARY SCIENCES | ENDOGENOUS ADRENOMEDULLIN | VASCULAR INTEGRITY | ENDOPLASMIC-RETICULUM STRESS | RENAL INJURY | CISPLATIN NEPHROTOXICITY | Antibiotics, Antineoplastic - pharmacology | eIF-2 Kinase - metabolism | Humans | Antibiotics, Antineoplastic - adverse effects | Kidney Glomerulus - injuries | Kidney Diseases - genetics | Cell Death - genetics | Kidney Diseases - chemically induced | Kidney Glomerulus - metabolism | Cell Death - drug effects | Streptozocin - adverse effects | Kidney Diseases - metabolism | eIF-2 Kinase - genetics | Cell Line | Kidney Tubules, Proximal - pathology | Kidney Diseases - pathology | Kidney Tubules, Proximal - injuries | Receptor Activity-Modifying Protein 2 - metabolism | Adrenomedullin - metabolism | Kidney Glomerulus - pathology | Streptozocin - pharmacology | Adrenomedullin - genetics | Mice, Knockout | Animals | Endoplasmic Reticulum Stress | Kidney Tubules, Proximal - metabolism | Receptor Activity-Modifying Protein 2 - genetics | Mice | Proteins | Blood sugar | Cell death | Genetically modified organisms | Biochemistry | Kidney diseases | Protein binding | Peptides | Syngeneic grafts | Epithelial cells | Streptozocin | Tunicamycin | Homeostasis | Adrenomedullin | Homology | Lethality | Glucose | Receptor activity modifying proteins | Ischemia | Rodents | Animal tissues | Calcitonin | Damage | Genetic modification | Injuries | University graduates | Chronic illnesses | Glucose transporter | Stresses | Stroke | Kidneys | Mortality | Organs | Tubules | Ribonucleic acid--RNA | Insulin | Embryos | Biological activity | Stress | Medicine | Ramps | Signaling | Protein kinase | Diabetes | Endoplasmic reticulum | Transporter | Kidney transplantation | Apoptosis | Index Medicus | RNA | Ribonucleic acid
Journal Article
The American Journal of Pathology, ISSN 0002-9440, 02/2019, Volume 189, Issue 2, pp. 449 - 466
Central retinal vein occlusion (CRVO) is an intractable disease that causes visual acuity loss with retinal ischemia, hemorrhage, and edema. In this study, we... 
RAMPS | ANGIOGENESIS | GROWTH | VEIN OCCLUSION | PATHOLOGY | HYPOXIA | RANIBIZUMAB
Journal Article
Journal of Atherosclerosis and Thrombosis, ISSN 1340-3478, 2015
Vascular endothelial cells play key roles in maintaining vascular and organ homeostasis. Adrenomedullin (AM), originally identified as a vasodilating peptide,... 
Adrenomedullin (AM) | Vascular endothelial cell | Receptor activity-modifying protein (RAMP) | Homeostasis | Vascular integrity
Journal Article
Journal of Atherosclerosis and Thrombosis, ISSN 1340-3478, 2015, Volume 22, Issue 7, pp. 647 - 653
Vascular endothelial cells play key roles in maintaining vascular and organ homeostasis. Adrenomedullin (AM), originally identified as a vasodilating peptide,... 
Journal Article
Journal of Hypertension, ISSN 0263-6352, 04/2018, Volume 36, Issue 4, pp. 876 - 891
Journal Article
Circulation, ISSN 0009-7322, 02/2013, Volume 127, Issue 7, pp. 842 - 853
Background-Revealing the mechanisms underlying the functional integrity of the vascular system could make available novel therapeutic approaches. We previously... 
endothelium | vasculature | arteriosclerosis | aging | edema | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | HYPOTENSIVE PEPTIDE | ENDOGENOUS PEPTIDE | BARRIER FUNCTION | ATHEROSCLEROSIS | CELL SENESCENCE | ISCHEMIA | GENE | PLASMA-LEVELS | PERIPHERAL VASCULAR DISEASE | RECEPTOR-LIKE RECEPTOR | Vasculitis - metabolism | Age Factors | Cadherins - metabolism | Kidney - pathology | Vasculitis - physiopathology | Oxidative Stress - physiology | Vasculitis - pathology | Fibrosis - metabolism | Antigens, CD - genetics | Antigens, CD - metabolism | Kidney - metabolism | Glomerulosclerosis, Focal Segmental - physiopathology | Cadherins - genetics | Kidney - physiopathology | Disease Models, Animal | Fibrosis - physiopathology | Arteriosclerosis - physiopathology | Endothelium, Vascular - physiopathology | Receptor Activity-Modifying Protein 2 - metabolism | Adrenomedullin - metabolism | Glomerulosclerosis, Focal Segmental - metabolism | Mice, Knockout | Edema - metabolism | Animals | Endothelium, Vascular - metabolism | Homeostasis - physiology | Receptor Activity-Modifying Protein 2 - genetics | Endothelium, Vascular - pathology | Arteriosclerosis - metabolism | Edema - physiopathology | Mice | Fibrosis - pathology | Arteriosclerosis - pathology | Edema - pathology | Leukocytes - metabolism | Glomerulosclerosis, Focal Segmental - pathology | Aging - metabolism | Homeostasis | Physiological aspects | Vascular endothelium | Research | Cellular control mechanisms | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2014, Volume 77, pp. 73 - 85
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2013, Volume 59, pp. 55 - 66
Journal Article