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Nature Chemistry, ISSN 1755-4330, 11/2016, Volume 8, Issue 11, pp. 1076 - 1082
Journal Article
ChemCatChem, ISSN 1867-3880, 06/2016, Volume 8, Issue 12, pp. 2023 - 2026
Biocatalysis employing imine reductases is a promising approach for the one‐step generation of chiral amines from ketones. The enzymes reported for this... 
amines | imine reductase | asymmetric synthesis | reductive amination | biocatalysis | TOOLBOX | CHEMISTRY, PHYSICAL | (S)-IMINE REDUCTASE | SELECTIVE REDUCTION | DEHYDROGENASE | ENZYME | SUBSTRATE | CHIRAL AMINE SYNTHESIS | (R)-IMINE REDUCTASE | OMEGA-TRANSAMINASES | CYCLIC IMINES | Enzymes | Synthesis | Amines | Catalysis | Ketones | Organic compounds
Journal Article
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 07/2008, Volume 73, Issue 13, pp. 4895 - 4902
A new, enantioselective synthesis of the influenza neuraminidase inhibitor prodrug oseltamivir phosphate 1 (Tamiflu) and its enantiomer ent-1 starting from... 
CHEMISTRY, ORGANIC | INHIBITOR OSELTAMIVIR | ANTIINFLUENZA | Dicarboxylic Acids - chemistry | Antiviral Agents - chemical synthesis | Molecular Structure | Oseltamivir - chemical synthesis | Phenols | Esters | Chemical properties | Hydrogenation | Analysis
Journal Article
ChemCatChem, ISSN 1867-3880, 04/2015, Volume 7, Issue 8, pp. 1302 - 1311
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2016, Volume 14, Issue 43, pp. 10249 - 10254
Journal Article
HETEROCYCLES, ISSN 0385-5414, 01/2017, Volume 95, Issue 2, pp. 1261 - 1271
The design of a recombinant whole-cell catalyst and its utilization in the asymmetric reduction of 1-methyl-3,4-dihydroisoquinoline chosen as a model substrate... 
KETONES | AMINATION | TOOLBOX | CHEMICALS | CHEMISTRY, ORGANIC | (R)-IMINE REDUCTASE | TRENDS
Journal Article
ChemBioChem, ISSN 1439-4227, 08/2015, Volume 16, Issue 12, pp. 1823 - 1823
Journal Article
Organic & Biomolecular Chemistry, ISSN 1477-0520, 11/2016, Volume 14, Issue 43, pp. 10249 - 10254
Application of amine transaminases (ATAs) for stereoselective amination of prochiral ketones represents an environmentally benign and economically attractive... 
Journal Article
ISSN 1477-0520, 11/2016, Volume 14, Issue 43, pp. 1249 - 1254
Application of amine transaminases (ATAs) for stereoselective amination of prochiral ketones represents an environmentally benign and economically attractive... 
Journal Article
ChemCatChem, ISSN 1867-3880, 06/2016, Volume 8, Issue 12, pp. 2171 - 2171
The cover shows the idea of the imine reductase‐catalyzed reductive amination of ketones: the direct preparation of chiral amines by merging ketones and... 
amines | imine reductase | asymmetric synthesis | reductive amination | biocatalysis
Journal Article
Organic Letters, ISSN 1523-7060, 09/2017, Volume 19, Issue 18, pp. 4806 - 4809
A highly efficient asymmetric synthesis of the Akt kinase inhibitor ipatasertib (1) is reported. The bicyclic pyrimidine 2 starting material was prepared via a... 
BIPHENYL SERIES | HYDROGENATION | ANALOGS | CHEMISTRY, ORGANIC | SCALE | IDENTIFICATION | DISCOVERY
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 12/2016, Volume 59, Issue 14, pp. 635 - 639
Journal Article
Organic Process Research & Development, ISSN 1083-6160, 03/2017, Volume 21, Issue 3, pp. 387 - 398
Journal Article
Nature Catalysis, ISSN 2520-1158, 01/2018, Volume 1, Issue 1, pp. 12 - 22
The past decade has seen a substantial increase in successful examples of the combination of chemo-and biocatalysis for multistep syntheses. This is driven by... 
ENZYMATIC RESOLUTION | LIGHT-DRIVEN BIOCATALYSIS | CASCADE REACTIONS | ASYMMETRIC-SYNTHESIS | AQUEOUS-MEDIA | CHEMISTRY, PHYSICAL | ARTIFICIAL METALLOENZYMES | STEREOSELECTIVE-SYNTHESIS | DIRECTED EVOLUTION | CATALYTIC RACEMIZATION | DYNAMIC KINETIC RESOLUTION
Journal Article
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