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Archives of Biochemistry and Biophysics, ISSN 0003-9861, 06/2015, Volume 576, pp. 1 - 1
Journal Article
Nature Cell Biology, ISSN 1465-7392, 08/2015, Volume 17, Issue 8, pp. 1049 - 1061
The TOR (target of rapamycin) kinase limits longevity by poorly understood mechanisms. Rapamycin suppresses the mammalian TORC1 complex, which regulates... 
EPITHELIAL-CELL LINE | GROWTH ARREST | DNA-DAMAGE | IN-VIVO | INFLAMMATORY CYTOKINE SECRETION | HUMAN FIBROBLASTS | TUMOR-CELLS | CANCER-THERAPY | REPLICATIVE SENESCENCE | P53 | CELL BIOLOGY | Up-Regulation | Fibroblasts - enzymology | Cell Proliferation | TOR Serine-Threonine Kinases - metabolism | Humans | Gene Expression Regulation, Neoplastic | Interleukin-1alpha - metabolism | Male | NF-kappa B - metabolism | RNA, Messenger - metabolism | Prostatic Neoplasms - secretion | Prostatic Neoplasms - immunology | Dose-Response Relationship, Drug | TOR Serine-Threonine Kinases - antagonists & inhibitors | Prostatic Neoplasms - genetics | TOR Serine-Threonine Kinases - genetics | Transfection | RNA Interference | Time Factors | Cellular Senescence | Inflammation Mediators - metabolism | Transcription, Genetic | Antineoplastic Agents - pharmacology | Interleukin-1alpha - genetics | Interleukin-6 - metabolism | Prostatic Neoplasms - drug therapy | Prostatic Neoplasms - pathology | Anti-Inflammatory Agents - pharmacology | Interleukin-1alpha - secretion | Sirolimus - metabolism | Tumor Burden | Mice, SCID | Sirolimus - pharmacology | Xenograft Model Antitumor Assays | Phenotype | Animals | Fibroblasts - drug effects | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Mitoxantrone - pharmacology | Interleukins | Aging | Genetic aspects | Properties | Phosphotransferases | Carcinogenesis | Health aspects | Cells
Journal Article
Journal of High Energy Physics, ISSN 1126-6708, 2018, Volume 2018, Issue 1, pp. 1 - 53
Journal Article
Aging Cell, ISSN 1474-9718, 08/2015, Volume 14, Issue 4, pp. 644 - 658
Summary The healthspan of mice is enhanced by killing senescent cells using a transgenic suicide gene. Achieving the same using small molecules would have a... 
dasatinib | plasminogen‐activated inhibitor | dependence receptors | quercetin | ephrins | PI3K delta | p21 | Dasatinib | Dependence receptors | Ephrins | Plasminogen-activated inhibitor | Quercetin | P21 | ENDOTHELIAL DYSFUNCTION | PLASMINOGEN-ACTIVATOR INHIBITOR-1 | EXPRESSION PROFILES | plasminogen-activated inhibitor | CELLULAR SENESCENCE | CANCER-THERAPY | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | LUNG-CANCER | SET ENRICHMENT ANALYSIS | GENE-EXPRESSION | IONIZING-RADIATION | TUMOR-GROWTH | Carotid Arteries - drug effects | Endonucleases - genetics | Plasminogen Activator Inhibitor 2 - genetics | Transcriptome | Gene Expression Profiling | Adipocytes - drug effects | Aging - genetics | Osteoporosis - metabolism | Ephrins - metabolism | Plasminogen Activator Inhibitor 2 - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Osteoporosis - genetics | Intervertebral Disc - pathology | Fibroblasts - metabolism | Endothelial Cells - metabolism | Intervertebral Disc - chemistry | Fibroblasts - pathology | Mesenchymal Stem Cells - pathology | Mice, Knockout | Dasatinib - pharmacology | Osteoporosis - pathology | Ephrins - genetics | Fibroblasts - drug effects | Mice | Endothelial Cells - pathology | bcl-X Protein - metabolism | Aging - metabolism | Aging - drug effects | bcl-X Protein - genetics | Cellular Senescence - drug effects | Phosphatidylinositol 3-Kinases - metabolism | Endonucleases - metabolism | DNA-Binding Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Mesenchymal Stem Cells - drug effects | Mesenchymal Stem Cells - metabolism | Heart - physiopathology | Cellular Senescence - genetics | Osteoporosis - prevention & control | DNA-Binding Proteins - genetics | Adipocytes - pathology | Aging - pathology | Phosphatidylinositol 3-Kinases - genetics | Animals | Quercetin - pharmacology | Adipocytes - metabolism | Heart - drug effects | Carotid Arteries - pathology | Intervertebral Disc - drug effects | Drug Combinations | Endothelial Cells - drug effects | Original
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2018, Volume 24, Issue 8, pp. 1246 - 1256
Journal Article
by Aaboud, M and Aad, G and Abbott, B and Abdinov, O and Abeloos, B and Abhayasinghe, D.K and Abidi, S.H and AbouZeid, O.S and Abraham, N.L and Abramowicz, H and Abreu, H and Abulaiti, Y and Acharya, B.S and Adachi, S and Adamczyk, L and Adelman, J and Adersberger, M and Adiguzel, A and Adye, T and Affolder, A.A and Afik, Y and Agheorghiesei, C and Aguilar-Saavedra, J.A and Ahmadov, F and Aielli, G and Akatsuka, S and Åkesson, T.P.A and Akilli, E and Akimov, A.V and Alberghi, G.L and Albert, J and Albicocco, P and Alconada Verzini, M.J and Alderweireldt, S and Aleksa, M and Aleksandrov, I.N and Alexa, C and Alexopoulos, T and Alhroob, M and Ali, B and Aliev, M and Alimonti, G and Alison, J and Alkire, S.P and Allaire, C and Allbrooke, B.M.M and Allen, B.W and Allport, P.P and Aloisio, A and Alonso, A and Alonso, F and Alpigiani, C and Alshehri, A.A and Alstaty, M.I and Alvarez Gonzalez, B and Álvarez Piqueras, D and Alviggi, M.G and Amadio, B.T and Amaral Coutinho, Y and Ambroz, L and Amelung, C and Amidei, D and Amor Dos Santos, S.P and Amoroso, S and Amrouche, C.S and Anastopoulos, C and Ancu, L.S and Andari, N and Andeen, T and Anders, J.K and Anders, C.F and Anderson, K.J and Andreazza, A and Andrei, V and Anelli, C.R and Angelidakis, S and Angelozzi, I and Angerami, A and Anisenkov, A.V and Annovi, A and Antel, C and Anthony, M.T and Antonelli, M and Antrim, D.J.A and Anulli, F and Aoki, M and Aperio Bella, L and Arabidze, G and Araque, J.P and Araujo Ferraz, V and Araujo Pereira, R and Arce, A.T.H and Ardell, R.E and Arduh, F.A and Arguin, J-F and Argyropoulos, S and Armbruster, A.J and Armitage, L.J and Armstrong, A and Arnaez, O and ... and ATLAS Collaboration and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States) and Partikel- och astropartikelfysik and Skolan för teknikvetenskap (SCI) and KTH and Fysik
Physics Letters B, ISSN 0370-2693, 09/2018, Volume 784, Issue C, pp. 173 - 191
The observation of Higgs boson production in association with a top quark pair ( ), based on the analysis of proton–proton collision data at a centre-of-mass... 
PHYSICS, NUCLEAR | SEARCH | ASTRONOMY & ASTROPHYSICS | PHYSICS, PARTICLES & FIELDS | Physics - High Energy Physics - Experiment | PHYSICS OF ELEMENTARY PARTICLES AND FIELDS | Fysik | Subatomär fysik | Physical Sciences | Subatomic Physics | Naturvetenskap | Natural Sciences
Journal Article