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biochemistry & molecular biology (10) 10
index medicus (9) 9
catalysis (7) 7
serine c-palmitoyltransferase - chemistry (7) 7
serine c-palmitoyltransferase - metabolism (7) 7
serine palmitoyltransferase (6) 6
animals (5) 5
biosynthesis (5) 5
sphingolipid synthesis (5) 5
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8-amino-7-oxononanoate synthase (4) 4
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acyltransferases - isolation & purification (3) 3
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palmitoyl coenzyme a - metabolism (3) 3
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research (3) 3
serine c-palmitoyltransferase (3) 3
sphingosine - metabolism (3) 3
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The Journal of Biochemistry, ISSN 0021-924X, 02/2019, Volume 165, Issue 2, pp. 185 - 195
Abstract Homoserine dehydrogenase from Thermus thermophilus (TtHSD) is a key enzyme in the aspartate pathway that catalyses the reversible conversion of... 
ACID | SPECIFICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | STEREOCHEMISTRY | RESOLUTION | catalytic residue | IDENTIFICATION | homoserine dehydrogenase | Thermus thermophilus | INHIBITION | ternary complex | LIVER ALCOHOL-DEHYDROGENASE | crystal structure | CATALYTIC MECHANISM | BINDING-SITES
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2016, Volume 113, Issue 10, pp. E1334 - E1342
We recently identified a previously unidentified sphingosine-1-phosphate (S1P) signaling mechanism that stimulates production of a key innate immune element,... 
Cathelicidin | ER stress | Innate immunity | Sphingosine-1-phosphate | Heat shock protein 90 | HSP90 | ACTIVATION | cathelicidin | MULTIDISCIPLINARY SCIENCES | KINASE | RECEPTOR | FACTOR-KAPPA-B | SPHINGOSINE 1-PHOSPHATE | UBIQUITINATION | innate immunity | DEGRADATION | sphingosine-1-phosphate | heat shock protein 90 | ENDOPLASMIC-RETICULUM ER | Lysophospholipids - metabolism | RNA-Binding Proteins - genetics | Humans | TNF Receptor-Associated Factor 2 - genetics | NF-kappa B - metabolism | Antimicrobial Cationic Peptides - metabolism | Nuclear Pore Complex Proteins - genetics | Sphingosine - metabolism | Antimicrobial Cationic Peptides - genetics | Receptors, Lysosphingolipid - metabolism | Cell Line | Signal Transduction | Nuclear Pore Complex Proteins - metabolism | Heat-Shock Proteins - metabolism | Cells, Cultured | TNF Receptor-Associated Factor 2 - metabolism | Phosphotransferases (Alcohol Group Acceptor) - genetics | Keratinocytes - cytology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Sphingosine - analogs & derivatives | Animals | Keratinocytes - metabolism | Endoplasmic Reticulum Stress | Cell Line, Tumor | Protein Binding | Microscopy, Fluorescence | RNA-Binding Proteins - metabolism | Physiological aspects | Cellular signal transduction | Peptides | Observations | Endoplasmic reticulum | Biological Sciences | PNAS Plus
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 14228 - 13
Journal Article
BBA - Proteins and Proteomics, ISSN 1570-9639, 2011, Volume 1814, Issue 11, pp. 1474 - 1480
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2009, Volume 284, Issue 23, pp. 15487 - 15495
Journal Article
The Journal of Nutrition, ISSN 0022-3166, 09/2017, Volume 147, Issue 9, p. 1631
Background: S-equol, which is enantioselectively produced from daidzein by gut microbiota, has been suggested as a chemopreventive agent against type 2... 
Physiological aspects | Hyperglycemia | Pancreatic beta cells | Cyclic adenylic acid
Journal Article
Journal of Nutrition, ISSN 0022-3166, 09/2017, Volume 147, Issue 9, pp. 1631 - 1639
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 08/2007, Volume 189, Issue 15, pp. 5749 - 5761
Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
SPHINGOMONAS-PAUCIMOBILIS | NKT CELLS | GEN-NOV | 8-AMINO-7-OXONONANOATE SYNTHASE | SPHINGOLIPID SYNTHESIS | CRYSTAL-STRUCTURE | KEY ENZYME | YEAST LCB1 | MICROBIOLOGY | 2-HYDROXY FATTY-ACID | HEREDITARY SENSORY NEUROPATHY | Serine C-Palmitoyltransferase - chemistry | Palmitoyl Coenzyme A - pharmacology | Sphingobacterium - enzymology | Bacterial Proteins - chemistry | Molecular Sequence Data | DNA, Bacterial - chemistry | Serine C-Palmitoyltransferase - genetics | Phylogeny | Microscopy, Immunoelectron | Cell Membrane - chemistry | Mass Spectrometry | Cloning, Molecular | Escherichia coli - metabolism | Conserved Sequence | Sphingosine - metabolism | Bdellovibrio - enzymology | Dimerization | Serine C-Palmitoyltransferase - isolation & purification | Eukaryotic Cells - enzymology | Amino Acid Sequence | Bacterial Proteins - antagonists & inhibitors | Gene Expression | Membrane Proteins - isolation & purification | Membrane Proteins - genetics | Bacterial Proteins - genetics | Catalytic Domain - genetics | Enzyme Inhibitors - pharmacology | Serine C-Palmitoyltransferase - antagonists & inhibitors | Sequence Analysis, DNA | Sequence Homology, Amino Acid | Sphingosine - analogs & derivatives | DNA, Bacterial - genetics | Membrane Proteins - antagonists & inhibitors | Membrane Proteins - chemistry | Escherichia coli - genetics | Kinetics | Spectrophotometry | Bacterial Proteins - isolation & purification | Biosynthesis | Research | Acetyl coenzyme A synthetase | Serine | Membrane proteins | Enzymes and Proteins
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2009, Volume 284, Issue 23, pp. 15487 - 15495
Journal Article
Biochimica et biophysica acta, ISSN 0006-3002, 11/2011, Volume 1814, Issue 11, p. 1474
Serine palmitoyltransferase, which is one of the α-oxamine synthase family enzymes, catalyzes the condensation reaction of L-serine and palmitoyl-CoA to form... 
Protons | Serine C-Palmitoyltransferase - chemistry | Carboxylic Acids - metabolism | Models, Molecular | Substrate Specificity | Serine C-Palmitoyltransferase - metabolism
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2008, Volume 283, Issue 12, pp. 7542 - 7553
Serine palmitoyltransferase (SPT) is a key enzyme of sphingolipid biosynthesis and catalyzes the pyridoxal 5'-phosphate (PLP)-dependent decarboxylative... 
8-AMINO-7-OXONONANOATE SYNTHASE | CLONING | LCB1 | SPHINGOLIPID SYNTHESIS | REACTION-MECHANISM | BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KEY ENZYME | COMPONENT | 5-AMINOLEVULINATE SYNTHASE | SACCHAROMYCES-CEREVISIAE
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2008, Volume 283, Issue 12, p. 7542
Serine palmitoyltransferase (SPT) is a key enzyme of sphingolipid biosynthesis and catalyzes the pyridoxal 5′-phosphate (PLP)-dependent decarboxylative... 
Journal Article
Journal Article
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