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1. Full Text Comprehensive genomic characterization of squamous cell lung cancers
by Hammerman, Peter S and Voet, Doug and Lawrence, Michael S and Voet, Doug and Jing, Rui and Cibulskis, Kristian and Sivachenko, Andrey and Stojanov, Petar and McKenna, Aaron and Lander, Eric S and Gabriel, Stacey and Getz, Gad and Imielinski, Marcin and Helman, Elena and Hernandez, Bryan and Pho, Nam H and Meyerson, Matthew and Chu, Andy and Hye-Chun, Jung E and Mungall, Andrew J and Pleasance, Erin and Robertson, A. Gordon and Sipahimalani, Payal and Stoll, Dominik and Balasundaram, Miruna and Birol, Inanc and Butterfield, Yaron S.N and Chuah, Eric and Coope, Robin J.N and Corbett, Richard and Dhalla, Noreen and Guin, Ranabir and He, An and Hirst, Carrie and Hirst, Martin and Holt, Robert A and Lee, Darlene and Li, Haiyan I and Mayo, Michael and Moore, Richard A and Mungall, Karen and Nip, Ka Ming and Olshen, Adam and Schein, Jacqueline E and Slobodan, Jared R and Tam, Angela and Thiessen, Nina and Varhol, Richard and Zeng, Thomas and Zhao, Yongjun and Jones, Steven J.M and Marra, Marco A and Saksena, Gordon and Cherniack, Andrew D and Schumacher, Stephen E and Tabak, Barbara and Carter, Scott L and Nguyen, Huy and Onofrio, Robert C and Crenshaw, Andrew and Ardlie, Kristin and Beroukhim, Rameen and Winckler, Wendy and Protopopov, Alexei and Zhang, Jianhua and Hadjipanayis, Angela and Lee, Semin and Xi, Ruibin and Yang, Lixing and Ren, Xiaojia and Zhang, Hailei and Shukla, Sachet and Chen, Peng-Chieh and Haseley, Psalm and Lee, Eunjung and Chin, Lynda and Park, Peter J and Kucherlapati, Raju and Socci, Nicholas D and Liang, Yupu and Schultz, Nikolaus and Borsu, Laetitia and Lash, Alex E and Viale, Agnes and Sander, Chris and Ladanyi, Marc and Auman, J. Todd and Hoadley, Katherine A and Wilkerson, Matthew D and Shi, Yan and Liquori, Christina and Meng, Shaowu and Li, Ling and Turman, Yidi J and Topal, Michael D and Tan, Donghui and Waring, Scot and Buda, Elizabeth and Walsh, Jesse and Jones, Corbin D and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and The Cancer Genome Atlas Research Network
Nature, ISSN 0028-0836, 09/2012, Volume 489, Issue 7417, pp. 519 - 525
Lung squamous cell carcinoma is a common type of lung cancer, causing approximately 400,000 deaths per year worldwide. Genomic alterations in squamous cell... 
GEFITINIB | ONCOGENE | AMPLIFICATION | GENE | LANDSCAPE | MULTIDISCIPLINARY SCIENCES | THERAPEUTIC TARGET | SENSITIVITY | MUTATIONS | COPY-NUMBER ALTERATION | CARCINOMA | Lung Neoplasms - genetics | Lung Neoplasms - drug therapy | Adenocarcinoma of Lung | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Genomics | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Mutation Rate | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Signal Transduction - genetics | Genes, p53 - genetics | Molecular Targeted Therapy | Mutation - genetics | Adenocarcinoma - drug therapy | Genes, p16 | Genome, Human - genetics | Adenocarcinoma - metabolism | Carcinoma, Squamous Cell - drug therapy | DNA Mutational Analysis | Gene Deletion | Adenocarcinoma - genetics | Squamous cell carcinoma | Lung cancer | Genetic research | Genetic aspects | Research | Observations | Genetic screening | Mortality | Cell cycle | DNA methylation | Genetics | Genomes | Mutation | Kinases | Chromosomes | Ovarian cancer
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2. Full Text Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
by Rudin, Charles M and Durinck, Steffen and Stawiski, Eric W and Poirier, John T and Modrusan, Zora and Shames, David S and Bergbower, Emily A and Guan, Yinghui and Shin, James and Guillory, Joseph and Rivers, Celina Sanchez and Foo, Catherine K and Bhatt, Deepali and Stinson, Jeremy and Gnad, Florian and Haverty, Peter M and Gentleman, Robert and Chaudhuri, Subhra and Janakiraman, Vasantharajan and Jaiswal, Bijay S and Parikh, Chaitali and Yuan, Wenlin and Zhang, Zemin and Koeppen, Hartmut and Wu, Thomas D and Stern, Howard M and Yauch, Robert L and Huffman, Kenneth E and Paskulin, Diego D and Illei, Peter B and Varella-Garcia, Marileila and Gazdar, Adi F and De Sauvage, Frederic J and Bourgon, Richard and Minna, John D and Brock, Malcolm V and Seshagiri, Somasekar
Nature Genetics, ISSN 1061-4036, 10/2012, Volume 44, Issue 10, pp. 1111 - 1116
Small-cell lung cancer (SCLC) is an exceptionally aggressive disease with poor prognosis. Here, we obtained exome, transcriptome and copy-number alteration... 
TARGET | NONSMALL CELL | COMPLEX | PATHWAY | KINASE | GROWTH | GENETICS & HEREDITY | MUTATIONS | DIFFERENTIATION | REARRANGEMENTS | CARCINOMA | Lung Neoplasms - genetics | Gene Expression | Genome-Wide Association Study | Protein Kinases - genetics | Humans | Lung Neoplasms - metabolism | Molecular Sequence Data | Small Cell Lung Carcinoma - genetics | DNA Copy Number Variations | SOXB1 Transcription Factors - metabolism | Exome | Small Cell Lung Carcinoma - metabolism | Gene Amplification | SOXB1 Transcription Factors - genetics | DNA Mutational Analysis | Oncogene Proteins, Fusion - genetics | Base Sequence | Cell Line, Tumor | High-Throughput Nucleotide Sequencing | Mutation | Physiological aspects | Lung cancer, Small cell | Genetic aspects | Research | Gene mutations | Protein kinases | Proteins | Genomes | Bioinformatics | Genes
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3. Full Text Napsin A and thyroid transcription factor-1 expression in carcinomas of the lung, breast, pancreas, colon, kidney, thyroid, and malignant mesothelioma
by Bishop, Justin A., MD and Sharma, Rajni, PhD and Illei, Peter B., MD
Human Pathology, ISSN 0046-8177, 2010, Volume 41, Issue 1, pp. 20 - 25
Summary Recent advances in the treatment of pulmonary adenocarcinoma have increased the need for accurate typing of non–small cell carcinomas.... 
Pathology | Napsin A | Thyroid transcription factor-1 (TTF-1) | Lung carcinoma | PULMONARY SURFACTANT | BEVACIZUMAB | ADENOCARCINOMA | TISSUE | TA02 | PLUS CARBOPLATIN | PATHOLOGY | TTF-1 | ASPARTIC PROTEINASE | CANCER | PACLITAXEL | Immunohistochemistry | Neoplasms - metabolism | Thyroid Nuclear Factor 1 | Pancreatic Neoplasms - metabolism | Tissue Array Analysis | Humans | Lung Neoplasms - metabolism | Nuclear Proteins - metabolism | Kidney Neoplasms - metabolism | Mesothelioma - diagnosis | Colonic Neoplasms - metabolism | Breast Neoplasms - metabolism | Transcription Factors - metabolism | Adenocarcinoma - diagnosis | Adenocarcinoma - metabolism | Mesothelioma - metabolism | Aspartic Acid Endopeptidases - metabolism | Biomarkers, Tumor - metabolism | Female | Lung Neoplasms - diagnosis | Thyroid Neoplasms - metabolism | Squamous cell carcinoma | Thyroid diseases | Respiratory agents | Breast cancer | Metastasis | Aspartic proteinases | Proteins | Thyroid cancer | Colon | Pancreas | Surfactants | Tumors | Skin cancer
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4. Full Text Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network
by Collisson, Eric A and Campbell, Joshua D and Brooks, Angela N and Berger, Alice H and Lee, William and Chmielecki, Juliann and Beer, David G and Cope, Leslie and Creighton, Chad J and Danilova, Ludmila and Ding, Li and Getz, Gad and Hammerman, Peter S and Hayes, D. Neil and Hernandez, Bryan and Herman, James G and Heymach, John V and Jurisica, Igor and Kucherlapati, Raju and Kwiatkowski, David and Ladanyi, Marc and Robertson, Gordon and Schultz, Nikolaus and Shen, Ronglai and Sinha, Rileen and Sougnez, Carrie and Tsao, Ming-Sound and Travis, William D and Weinstein, John N and Wigle, Dennis A and Wilkerson, Matthew D and Chu, Andy and Cherniack, Andrew D and Hadjipanayis, Angela and Rosenberg, Mara and Weisenberger, Daniel J and Laird, Peter W and Radenbaugh, Amie and Ma, Singer and Stuart, Joshua M and Byers, Lauren Averett and Baylin, Stephen B and Govindan, Ramaswamy and Meyerson, Matthew and Gabriel, Stacey B and Cibulskis, Kristian and Kim, Jaegil and Stewart, Chip and Lichtenstein, Lee and Lander, Eric S and Lawrence, Michael S and Getz, E and Fulton, Robert and Fulton, Lucinda L and McLellan, Michael D and Wilson, Richard K and Ye, Kai and Fronick, Catrina C and Maher, Christopher A and Miller, Christopher A and Wendl, Michael C and Cabanski, Christopher and Mardis, Elaine and Wheeler, David and Balasundaram, Miruna and Butterfield, Yaron S. N and Carlsen, Rebecca and Chuah, Eric and Dhalla, Noreen and Guin, Ranabir and Hirst, Carrie and Lee, Darlene and Li, Haiyan I and Mayo, Michael and Moore, Richard A and Mungall, Andrew J and Schein, Jacqueline E and Sipahimalani, Payal and Tam, Angela and Varhol, Richard and Robertson, A. Gordon and Wye, Natasja and Thiessen, Nina and Holt, Robert A and Jones, Steven J.M and Marra, Marco A and Imielinski, Marcin and Onofrio, Robert C and Hodis, Eran and Zack, Travis and Helman, Elena and Pedamallu, Chandra Sekhar and Mesirov, Jill and Saksena, Gordon and Schumacher, Steven E and Carter, Scott L and Garraway, Levi and Beroukhim, Rameen and Lee, Semin and Mahadeshwar, Harshad S and ...
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7511, pp. 543 - 550
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5. Full Text Exosomes from human saliva as a source of microRNA biomarkers
by Michael, A and Bajracharya, SD and Yuen, PST and Zhou, H and Star, RA and Illei, GG and Alevizos, I
Oral Diseases, ISSN 1354-523X, 01/2010, Volume 16, Issue 1, pp. 34 - 38
Objective:  The aim of this study was to examine the presence of microRNAs (miRNAs) within exosomes isolated from human saliva and to optimize and test methods... 
microRNA | biomarkers | salivary exosomes | Salivary exosomes | Biomarkers | MicroRNA | CELLS | SIGNATURES | RNAS | MICROVESICLES | DIAGNOSTIC BIOMARKERS | IMMUNOLOGY | URINARY EXOSOMES | DENTISTRY, ORAL SURGERY & MEDICINE | PROSTATE-CANCER | PROTEINS | EXPRESSION | MicroRNAs - isolation & purification | Oligonucleotide Array Sequence Analysis | Humans | Biomarkers - analysis | MicroRNAs - metabolism | Exosomes - chemistry | Saliva - chemistry | Case-Control Studies | Sjogren's Syndrome - genetics | Polymerase chain reaction | Biological markers | Kidney diseases
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6. Full Text GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas
by Cimino-Mathews, Ashley, MD and Subhawong, Andrea P., MD and Illei, Peter B., MD and Sharma, Rajni, PhD and Halushka, Marc K., MD, PhD and Vang, Russell, MD and Fetting, John H., MD and Park, Ben Ho, MD, PhD and Argani, Pedram, MD
Human Pathology, ISSN 0046-8177, 2013, Volume 44, Issue 7, pp. 1341 - 1349
Summary GATA3 plays an integral role in breast luminal cell differentiation and is implicated in breast cancer progression. GATA3 immunohistochemistry is a... 
Pathology | Breast carcinoma | Metaplastic carcinoma | GATA3 | Metastatic breast carcinoma | SURVIVAL | SUBTYPE | LUMINAL CELL FATE | PATHOLOGY | TUMORS | ESTROGEN-RECEPTOR | HETEROGENEITY | CANCER METASTASES | HORMONE RESPONSE | DIFFERENTIATION | MAMMARY-GLAND | Receptors, Estrogen - metabolism | Lymph Nodes - pathology | Tissue Array Analysis | Humans | Middle Aged | Receptor, ErbB-2 - metabolism | Phyllodes Tumor - metabolism | Lymphatic Metastasis | Breast Neoplasms - metabolism | Receptors, Progesterone - metabolism | Immunohistochemistry - methods | Breast Neoplasms - pathology | Biomarkers, Tumor - metabolism | Phyllodes Tumor - diagnosis | Adult | Female | Neoplasm Staging | Carcinoma, Ductal, Breast - metabolism | GATA3 Transcription Factor - metabolism | Carcinoma, Ductal, Breast - secondary | Immunohistochemistry | Carcinoma | Estrogen | Development and progression | Breast cancer | Metastasis | Progesterone | Cancer | Labeling | Patients | Tumors
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7. Full Text Deficient CD4+CD25high T Regulatory Cell Function in Patients with Active Systemic Lupus Erythematosus
by Valencia, Xavier and Yarboro, Cheryl and Illei, Gabor and Lipsky, Peter E
The Journal of Immunology, ISSN 0022-1767, 02/2007, Volume 178, Issue 4, pp. 2579 - 2588
CD4(+)CD25(+) T regulatory cells (Tregs) play an essential role in maintaining immunologic homeostasis and preventing autoimmunity. Systemic lupus... 
Forkhead Transcription Factors - immunology | Forkhead Transcription Factors - biosynthesis | T-Lymphocytes, Regulatory - metabolism | Cell Proliferation | Gene Expression Regulation - immunology | Humans | Middle Aged | Self Tolerance | Lupus Erythematosus, Systemic - metabolism | Male | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Lymphocyte Activation - immunology | Lupus Erythematosus, Systemic - immunology | Adult | Female | Aged | Lupus Erythematosus, Systemic - pathology | Cytokines - biosynthesis | Cytokines - immunology
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8. Full Text Urinary exosomal transcription factors, a new class of biomarkers for renal disease
by Zhou, Hua and Cheruvanky, Anita and Hu, Xuzhen and Matsumoto, Takayuki and Hiramatsu, Noriyuki and Cho, Monique E and Berger, Alexandra and Leelahavanichkul, Asada and Doi, Kent and Chawla, Lakhmir S and Illei, Gabor G and Kopp, Jeffrey B and Balow, James E and Austin, Howard A and Yuen, Peter S.T and Star, Robert A
Kidney International, ISSN 0085-2538, 09/2008, Volume 74, Issue 5, pp. 613 - 621
Urinary exosomes are excreted from all nephron segments and constitute a rich source of intracellular kidney injury biomarkers. To study whether they contain... 
FSGS | transcription factor | WT-1 | exosomes | ATF3 | AKI | Exosomes | Transcription factor | ACUTE KIDNEY INJURY | MESSENGER-RNA EXPRESSION | GELATINASE-ASSOCIATED LIPOCALIN | SERUM CREATININE | GLOMERULAR-FILTRATION-RATE | DIAGNOSTIC MARKER | CARDIAC-SURGERY | GENE-EXPRESSION | CYSTATIN-C | UROLOGY & NEPHROLOGY | ISCHEMIA-REPERFUSION | Acute Kidney Injury - urine | Biomarkers - urine | Glomerulosclerosis, Focal Segmental - urine | Humans | Middle Aged | Male | Kidney Diseases - urine | Case-Control Studies | Cisplatin - toxicity | Reperfusion Injury - urine | Gene Products, vpr - genetics | Adult | Acute Kidney Injury - chemically induced | Intracellular Signaling Peptides and Proteins - genetics | WT1 Proteins - urine | Membrane Proteins - genetics | Rats | Mice, Transgenic | Transcription Factors - urine | Podocytes - pathology | Kidney - injuries | Rats, Sprague-Dawley | Animals | Podocytes - drug effects | Podocytes - physiology | Activating Transcription Factor 3 - urine | Aged | Mice | Index Medicus | CKD
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9. Full Text Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer
by Zheng, Lei and Foley, Kelly and Huang, Lanqing and Leubner, Ashley and Mo, Guanglan and Olino, Kelly and Edil, Barish H and Mizuma, Masamichi and Sharma, Rajni and Le, Dung T and Anders, Robert A and Illei, Peter B and van Eyk, Jennifer E and Maitra, Anirban and Laheru, Daniel and Jaffee, Elizabeth M
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 4, p. e19390
The aggressiveness of pancreatic ductal adenocarcinoma (PDA) is characterized by its high metastatic potential and lack of effective therapies, which is the... 
THERAPY | PROTEIN | TUMOR VACCINE | IMMUNOTHERAPY | ADENOCARCINOMA | GROWTH | BIOLOGY | IMMUNE ACTIVATION | MESENCHYMAL TRANSITION | EXPRESSION | PROGRESSION | Liver - pathology | Phosphorylation | Pancreatic Neoplasms - metabolism | Humans | Epithelial-Mesenchymal Transition - drug effects | Neoplasms, Experimental - pathology | Neoplasm Metastasis | Liver - drug effects | RNA Interference | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Female | Cell Membrane - metabolism | Annexin A2 - immunology | Pancreatic Neoplasms - prevention & control | Tumor Cells, Cultured | Antibodies, Monoclonal - immunology | Antigens, Neoplasm - genetics | Antigens, Neoplasm - immunology | Neoplasm Invasiveness | Antibodies, Monoclonal - pharmacology | Liver - metabolism | Mice, Inbred C57BL | Pancreatic Neoplasms - pathology | Neoplasms, Experimental - prevention & control | Blotting, Western | Cancer Vaccines - immunology | Cell Movement - drug effects | Disease-Free Survival | Tyrosine - metabolism | Animals | Annexin A2 - genetics | Cell Line, Tumor | Biomarkers, Tumor - genetics | Mice | Neoplasms, Experimental - metabolism | Annexin A2 - metabolism | Biomarkers, Tumor - immunology | Tyrosine - genetics | Viral antibodies | Tyrosine | Antigens | Pancreatic cancer | Vaccination | Antibodies | Phenols | Vaccines | Metastasis | Transforming growth factors | Annexins | Protein binding | Adenocarcinoma | Animal models | Calcium | Mesenchyme | Physicians | Colorectal cancer | Clinical trials | Cytotoxicity | Oncology | Phospholipids | Drug development | Cell surface | Metastases | Proteins | Granulocytes | Listeria | Lymphocytes | Surgery | Localization | Cell survival | Cytokines | RNA-mediated interference | Gene expression | Ribonucleic acid--RNA | Survival | Medicine | Pathology | Nitric oxide | Cytoskeleton | Autoimmune diseases | Tumors | Cancer | Guanosinetriphosphatase | RNA | Ribonucleic acid
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10. Full Text Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas
by Cimino-Mathews, Ashley, MD and Subhawong, Andrea P., MD and Elwood, Hillary, MD and Warzecha, Hind Nassar, MD and Sharma, Rajni, PhD and Park, Ben Ho, MD, PhD and Taube, Janis M., MD and Illei, Peter B., MD and Argani, Pedram, MD
Human Pathology, ISSN 0046-8177, 2013, Volume 44, Issue 6, pp. 959 - 965
Summary The transcription factor Sox10 mediates the differentiation of neural crest–derived cells, and Sox10 labeling by immunohistochemistry (IHC) is used... 
Pathology | Breast carcinoma | Metaplastic carcinoma | Myoepithelial | Sox10 | Basal-like carcinoma | GENE | NEOPLASMS | MARKER | MOUSE | PATHOLOGY | CANCER