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by Ogihara, Toshio and Saruta, Takao and Rakugi, Hiromi and Saito, Ikuo and Shimamoto, Kazuaki and Matsuoka, Hiroaki and Shimada, Kazuyuki and Ito, Sadayoshi and Horiuchi, Masatsugu and Imaizumi, Tsutomu and Takishita, Shuichi and Higaki, Jitsuo and Katayama, Shigehiro and Kimura, Genjiroh and Umemura, Satoshi and Ura, Nobuyuki and Hayashi, Koichi and Odawara, Masato and Tanahashi, Norio and Ishimitsu, Toshihiko and Kashihara, Naoki and Morita, Satoshi and Teramukai, Satoshi and Anno, T and Aoyama, S and Arima, N and Bando, Y and Dohi, Y and Fujioka, H and Fukuda, M and Fukuda, S and Fukuta, M and Futamura, Y and Hirakawa, Y and Imaeda, K and Imai, H and Imamura, A and Ito, M and Ito, O and Ito, T and Iwa, T and Izumi, J and Kaga, Y and Kanematsu, K and Kato, Y and Kawata, Y and Kitamura, T and Kobayashi, K and Koyasu, M and Kuwabara, S and Kuzuya, M and Maekawa, M and Mihara, H and Mitsuguchi, F and Murohara, T and Narita, T and Negi, K and Numaguchi, Y and Ohya, T and Okayama, N and Okuma, K and Ozaki, N and Ozeki, N and Sato, K and Sawada, T and Seino, Y and Suezawa, M and Suzuki, T and Suzuki, Y and Takahashi, N and Takahashi, R and Tanaka, N and Wakida, Y and Watanuki, H and Watarai, M and Yamada, K and Yamashita, S and Yoshikane, M and Goto, M and Ishida, Y and Kimura, H and Takahashi, K and Yashima, N and Abe, Y and Fujiwara, S and Higashino, H and Kaizuka, M and Minami, O and Ogiu, Y and Osanai, T and Sasaki, T and Sato, A and Sugimoto, K and Takahashi, H and Tanabe, K and Azuma, D and Ibuki, C and Inoya, H and Iyo, T and Kusaka, M and ...
Journal of Hypertension, ISSN 0263-6352, 10/2014, Volume 32, Issue 10, pp. 2054 - 2063
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2017, Volume 25, Issue 14, pp. 3719 - 3735
With the aim to discover a gastric antisecretory agent more potent than the existing proton pump inhibitors, novel 3,4-dihydro-1... 
Potassium-competitive acid blockers | H+,K+-ATPase | Docking analysis | 3,4-Dihydro-1H-spiro[naphthalene-2,2′-piperidin]-1-one derivatives | S-Enantiomer | CHEMISTRY, MEDICINAL | GASTROESOPHAGEAL-REFLUX DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | 3,4-Dihydro-1H-spirotnaphthalene-2,2 '-piperidin]-1-one derivatives | Histamine - toxicity | Potassium - metabolism | Area Under Curve | Half-Life | Structure-Activity Relationship | Gastric Mucosa - metabolism | Gastric Acid - secretion | H(+)-K(+)-Exchanging ATPase - chemistry | Spiro Compounds - chemical synthesis | Gastric Mucosa - drug effects | Inhibitory Concentration 50 | Piperidines - pharmacokinetics | Proton Pump Inhibitors - chemical synthesis | Drug Evaluation, Preclinical | Binding Sites | Spiro Compounds - chemistry | Naphthalenes - chemistry | Piperidines - chemistry | H(+)-K(+)-Exchanging ATPase - metabolism | Rats | Piperidines - chemical synthesis | Spiro Compounds - pharmacokinetics | Potassium - chemistry | Administration, Intravenous | Animals | Proton Pump Inhibitors - chemistry | Proton Pump Inhibitors - pharmacokinetics | Gastric Mucosa - secretion | ROC Curve | Molecular Docking Simulation | Gastric Acid - metabolism | Antacids | Resveratrol | Gastroesophageal reflux | Dimethylformamide | Chemical tests and reagents | Lithium compounds | Cytokinins | Histamine | Proton pump inhibitors | Metallocenes | Derivatives (Financial instruments) | High performance liquid chromatography | Adenosine triphosphatase
Journal Article
by Wakai, Kenji and Hamajima, Nobuyuki and Okada, Rieko and Naito, Mariko and Morita, Emi and Hishida, Asahi and Kawai, Sayo and Nishio, Kazuko and Yin, Guang and Asai, Yatami and Matsuo, Keitaro and Hosono, Satoyo and Ito, Hidemi and Watanabe, Miki and Kawase, Takakazu and Suzuki, Takeshi and Tajima, Kazuo and Tanaka, Keitaro and Higaki, Yasuki and Hara, Megumi and Imaizumi, Takeshi and Taguchi, Naoto and Nakamura, Kazuyo and Nanri, Hinako and Sakamoto, Tatsuhiko and Horita, Mikako and Shinchi, Koichi and Kita, Yoshikuni and Turin, Tanvir Chowdhury and Rumana, Nahid and Matsui, Kenji and Miura, Katsuyuki and Ueshima, Hirotsugu and Takashima, Naoyuki and Nakamura, Yasuyuki and Suzuki, Sadao and Ando, Ryosuke and Hosono, Akihiro and Imaeda, Nahomi and Shibata, Kiyoshi and Goto, Chiho and Hattori, Nami and Fukatsu, Mitsuru and Yamada, Tamaki and Tokudome, Shinkan and Takezaki, Toshiro and Niimura, Hideshi and Hirasada, Kazuyo and Nakamura, Akihiko and Tatebo, Masaya and Ogawa, Shin and Tsunematsu, Noriko and Chiba, Shirabe and Mikami, Haruo and Kono, Suminori and Ohnaka, Keizo and Takayanagi, Ryoichi and Watanabe, Yoshiyuki and Ozaki, Etsuko and Shigeta, Masako and Kuriyama, Nagato and Yoshikawa, Aya and Matsui, Daisuke and Watanabe, Isao and Inoue, Kaoru and Ozasa, Kotaro and Mitani, Satoko and Arisawa, Kokichi and Uemura, Hirokazu and Hiyoshi, Mineyoshi and Takami, Hidenobu and Yamaguchi, Miwa and Nakamoto, Mariko and Takeda, Hideo and Kubo, Michiaki and Tanaka, Hideo and J-MICC Study Grp and J-MICC Study Group
Journal of Epidemiology, ISSN 0917-5040, 2011, Volume 21, Issue 3, pp. 223 - 235
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2017, Volume 25, Issue 13, pp. 3298 - 3314
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2018, Volume 115, Issue 29, pp. E6863 - E6870
Journal Article
JOURNAL OF PHYSICAL CHEMISTRY C, ISSN 1932-7447, 04/2019, Volume 123, Issue 16, pp. 10529 - 10535
A precise understanding of the near-field distributions of plasmonic nanostructures is indispensable for their practical applications. In this study, we... 
SURFACE-PLASMONS | NANOHOLE | FILMS | MATERIALS SCIENCE, MULTIDISCIPLINARY | FLUORESCENCE ENHANCEMENT | CHEMISTRY, PHYSICAL | LIGHT TRANSMISSION | NANOSCIENCE & NANOTECHNOLOGY | GENERATION | ARRAYS
Journal Article
Chemistry Letters, ISSN 0366-7022, 9/2019, Volume 48, Issue 9, pp. 1119 - 1121
We visualized spatial distributions of fluorescence excitation probability on a two-dimensional periodical gold nanohole array using an aperture-type scanning... 
Near-field imaging | Metallic nanohole array | PLASMON | ENHANCEMENT | Fluorescence | LIGHT TRANSMISSION | CHEMISTRY, MULTIDISCIPLINARY | MOLECULES
Journal Article
The Journal of Physical Chemistry C, ISSN 1932-7447, 04/2018, Volume 122, Issue 13, pp. 7399 - 7409
We investigated the spectral and spatial characteristics of plasmons induced in chemically synthesized triangular gold nano- and microplates by aperture-type... 
ENERGY-LOSS SPECTROSCOPY | LOCAL-DENSITY | SURFACE-PLASMONS | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | NANOSTRUCTURES | ANTENNAS | RESONANCES | EDGE
Journal Article
Chemical Physics Letters, ISSN 0009-2614, 02/2016, Volume 646, pp. 179 - 184
We performed dye-assisted two-photon-excitation imaging of plasmon modes in single gold nanoplates using a scanning near-field optical microscope. We observed... 
LOCAL-DENSITY | NANOPARTICLES | PHOTOLUMINESCENCE | FLUORESCENCE | LUMINESCENCE | AQUEOUS-SOLUTION APPROACH | ENHANCEMENT | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | SURFACE | CHEMISTRY, PHYSICAL | NANORODS | ABSORPTION
Journal Article
The Journal of Physical Chemistry C, ISSN 1932-7447, 07/2015, Volume 119, Issue 28, pp. 16215 - 16222
We applied time-resolved near-field optical microscopic measurements with ultrashort light pulses of ∼16 fs duration to observe plasmon dephasing processes in... 
PHOTOLUMINESCENCE | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOPARTICLE | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | ENHANCED RAMAN-SCATTERING | NANOANTENNAS | MODES | METALS | DYNAMICS | RESONANCES | NANOWIRES | SURFACE-PLASMON
Journal Article
The Journal of Physical Chemistry Letters, ISSN 1948-7185, 07/2018, Volume 9, Issue 14, pp. 4075 - 4081
Precise understanding of the spatiotemporal characteristics of plasmons is essential for the development of applications of plasmonic nanoparticles. In this... 
LOCAL-DENSITY | SPECTROSCOPY | PARTICLE | MATERIALS SCIENCE, MULTIDISCIPLINARY | LIGHT | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | TIME | NANORODS | RESONANCES | EDGE
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 06/2010, Volume 160, Issue 3, pp. 386 - 393
Summary Recent studies have demonstrated that the complement system participates in the regulation of T cell functions. To address the local biosynthesis of... 
Crohn's disease | IBD | ulcerative colitis | IL-17 | IL‐17 | Ulcerative colitis | CROHNS-DISEASE | FAMILY-MEMBERS | ULCERATIVE-COLITIS | KAPPA-B-ALPHA | IMMUNOLOGY | PROTEIN-KINASE KINASE | COLONIC SUBEPITHELIAL MYOFIBROBLASTS | INTESTINAL EPITHELIAL-CELLS | RESPONSES | GENE-EXPRESSION | T-CELLS | I-kappa B Proteins - immunology | Humans | Colitis, Ulcerative - genetics | Crohn Disease - metabolism | Colon - immunology | Male | Interleukin-17 - pharmacology | Colitis, Ulcerative - immunology | RNA, Messenger - biosynthesis | Time Factors | Intestinal Mucosa - immunology | Mitogen-Activated Protein Kinase 1 - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Complement C3 - genetics | Mitogen-Activated Protein Kinase 1 - immunology | NF-KappaB Inhibitor alpha | Transduction, Genetic | Colon - pathology | Colitis, Ulcerative - metabolism | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Interleukin-17 - genetics | Colitis, Ulcerative - pathology | Imidazoles - pharmacology | p38 Mitogen-Activated Protein Kinases - immunology | Colon - metabolism | Complement C3 - immunology | Flavonoids | Crohn Disease - pathology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mutation | Intestinal Mucosa - pathology | Mitogen-Activated Protein Kinase 1 - metabolism | Crohn Disease - genetics | RNA, Messenger - immunology | Intestinal Mucosa - metabolism | Adenoviridae | Interleukin-17 - immunology | I-kappa B Proteins - metabolism | I-kappa B Proteins - genetics | Dose-Response Relationship, Drug | Reverse Transcriptase Polymerase Chain Reaction - methods | Female | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | RNA, Messenger - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Interleukin-17 - biosynthesis | Crohn Disease - immunology | Gene Expression Regulation - drug effects | Complement C3 - biosynthesis | Pyridines - pharmacology | Cell research | Messenger RNA | Interleukins | T cells | Protein kinases | Enzyme-linked immunosorbent assay | Inflammatory bowel disease | Cytokines | Kinases | Rodents | Translational Studies
Journal Article