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JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 04/2019, Volume 81, p. 47
A pool of CD4+T cells harboring HIV-1 proviruses is established early during HIV-1 infection and persists despite years of suppressive combination... 
Antiretroviral drugs | Pathogenesis | Proviruses | Viruses | Lymphocytes T | Infections | Ribonucleic acid--RNA | Biological activity | Antiretroviral therapy | CD4 antigen | Proteins | Antiretroviral agents | Lymphocytes | Human immunodeficiency virus--HIV | Mutation
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 515, Issue 7525, pp. 138 - 142
The isolation of human monoclonal antibodies is providing important insights into the specificities that underlie broad neutralization of HIV-1 (reviewed in... 
B-CELLS | SPECIFICITIES | MULTIDISCIPLINARY SCIENCES | SERA | IMMUNODEFICIENCY-VIRUS TYPE-1 | ENV TRIMERS | VULNERABILITY | GP120 | HUMAN MONOCLONAL-ANTIBODIES | CLEAVAGE | DEPENDENT EPITOPE | Immunoglobulin Fab Fragments - ultrastructure | Antibody Specificity | Epitope Mapping | HIV Envelope Protein gp41 - immunology | Humans | AIDS Vaccines - immunology | Molecular Sequence Data | Leukocytes, Mononuclear | HIV Envelope Protein gp41 - chemistry | Virus Internalization - drug effects | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | Antibodies, Neutralizing - immunology | Receptors, CCR5 - metabolism | HIV Antibodies - immunology | Conserved Sequence | Inhibitory Concentration 50 | HIV Envelope Protein gp120 - chemistry | HIV Antibodies - pharmacology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Cell Line | Immunoglobulin Fab Fragments - genetics | HIV-1 - drug effects | Antibodies, Monoclonal - pharmacology | Models, Molecular | Antibodies, Neutralizing - pharmacology | Antibody Affinity | Antibodies, Neutralizing - genetics | HIV Antibodies - chemistry | AIDS Vaccines - chemistry | Antibodies, Monoclonal - genetics | HIV-1 - immunology | Antibodies, Neutralizing - chemistry | Immunoglobulin Fab Fragments - chemistry | Cell Membrane - virology | Epitopes - chemistry | HIV Antibodies - genetics | Immunoglobulin Fab Fragments - immunology | CD4 Antigens - metabolism | Viral antibodies | Care and treatment | Antibodies | Physiological aspects | Genetic aspects | Research | HIV infection | Antigenic determinants | Amino acids | Mutation | Vaccines | Human immunodeficiency virus--HIV | Binding sites | Index Medicus
Journal Article
Science Signaling, ISSN 1945-0877, 07/2017, Volume 10, Issue 488
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2014, Volume 10, Issue 1, p. e1003890
Despite antiretroviral therapy (ART), some HIV-infected persons maintain lower than normal CD4(+) T-cell counts in peripheral blood and in the gut mucosa. This... 
ACTIVATION | CD4(+) T-CELLS | RECEPTOR | MICROBIOLOGY | RESTORATION | MUCOSAL IMMUNE RECONSTITUTION | THERAPY | VIROLOGY | PLASMA-LEVELS | LYMPHOID-TISSUE | EXPANSION | TH17 | PARASITOLOGY | Inflammation - pathology | Intestinal Mucosa - metabolism | CD8-Positive T-Lymphocytes - pathology | Fibrin Fibrinogen Degradation Products - metabolism | Humans | Middle Aged | Colitis - pathology | Colon - immunology | Male | Monocytes - metabolism | Monocytes - immunology | CD4-Positive T-Lymphocytes - pathology | Interleukin-7 - administration & dosage | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | CD4-CD8 Ratio | Inflammation - metabolism | HIV Infections - pathology | Inflammation - drug therapy | Intestinal Mucosa - immunology | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | Colitis - drug therapy | Colitis - immunology | Integrins - biosynthesis | Fibrin Fibrinogen Degradation Products - immunology | Neutrophil Infiltration - drug effects | Neutrophils - pathology | HIV Infections - blood | Colon - pathology | Integrins - immunology | CD4-Positive T-Lymphocytes - metabolism | Neutrophils - immunology | Lipopolysaccharide Receptors - immunology | Inflammation - immunology | Colon - metabolism | Lipopolysaccharide Receptors - blood | Colitis - metabolism | HIV Infections - drug therapy | CD8-Positive T-Lymphocytes - immunology | Chronic Disease | Intestinal Mucosa - pathology | Prevention | Physiological aspects | Inflammation | Interleukins | HIV infection | Health aspects | Medical research | HIV | Pathogenesis | Biopsy | Mortality | Biomarkers | Infections | Human immunodeficiency virus | Drug therapy
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2017, Volume 7, Issue 1, p. 43441
Interleukin (IL)-27, a member of the IL-12 cytokine family, plays an important and diverse role in the function of the immune system. We have previously... 
Antiviral agents | Reactive oxygen species | Dendritic cells | Cytokines | Herpes simplex | Interleukin 12 | Superoxide dismutase | Superoxide | Macrophages | Interleukin 27 | NAD(P)H oxidase | Polymerase chain reaction | Monocytes | Influenza | Nitric oxide | Immune system
Journal Article
European Journal of Immunology, ISSN 0014-2980, 06/2008, Volume 38, Issue 6, pp. 1621 - 1630
IL‐15 is a member of the γ chain‐dependent cytokines and known to affect innate and CD8+ adaptive immune responses. Despite a growing interest in the use of... 
Immune regulation | Cytokines | Regulatory T cells | T cells | Regulatory T cels
Journal Article
Science signaling, ISSN 1945-0877, 07/2017, Volume 10, Issue 488, p. eaah5054
We previously identified Ku70, a subunit of a DNA repair protein complex, as a cytosolic DNA sensor that induces the production of interferon-λ1 (IFN-λ1) by... 
DNA, Viral - immunology | Humans | Interleukins - immunology | HEK293 Cells | Interferons - metabolism | Ku Autoantigen - metabolism | Membrane Proteins - metabolism | Immunity, Innate | Macrophages - immunology | Protein Transport
Journal Article
Journal Article