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Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1177 - 15
Journal Article
Journal of Epidemiology and Community Health, ISSN 0143-005X, 03/2011, Volume 65, Issue 3, pp. 230 - 240
BackgroundThe effects of coffee and green, black and oolong teas and caffeine intake on cardiovascular disease (CVD) mortality have not been well defined in... 
Hypertension | Tea | Body mass index | Green teas | Mortality | Research reports | Men | Cardiovascular diseases | Congenital heart defects | Research universities | Universities | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | MYOCARDIAL-INFARCTION | REDUCED RISK | DRINKING | JACC | REGRESSION-MODELS | GENDER | CORONARY-HEART-DISEASE | HYPERTENSION | CANCER | CYP1A2 GENOTYPE | Beverages - adverse effects | Japan - epidemiology | Multivariate Analysis | Caffeine - analysis | Confidence Intervals | Age Distribution | Beverages - utilization | Follow-Up Studies | Humans | Middle Aged | Male | Coffee - metabolism | Alcohol Drinking | Socioeconomic Factors | Tea - metabolism | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Adult | Female | Stroke - epidemiology | Surveys and Questionnaires | Retrospective Studies | Stroke - mortality | Caffeine - metabolism | Cardiovascular Diseases - etiology | Risk Factors | Diabetes Mellitus | Drinking Behavior | Stroke - etiology | Confounding Factors (Epidemiology) | Sex Factors | Aged | Demographic aspects | Patient outcomes | Japan | Research | Coffee habit | Health aspects | Studies | Womens health | Cardiovascular disease | Coffee | Health risk assessment | Index Medicus | Inventories | Stroke | green tea | Drinking | males | Coronary heart disease | Risk factors | tea | Beverages | Females | Caffeine | Cancer
Journal Article
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 05/2019, Volume 15, Issue 5, pp. 499 - 499
Time-resolved direct observations of proteins in action provide essential mechanistic insights into biological processes. Here, we present mechanisms of action... 
POSITION | PDI | BIOCHEMISTRY & MOLECULAR BIOLOGY | ERO1-ALPHA | CHAPERONE | BINDING | SCATTERING | B' DOMAIN | Atomic force microscopy | Hydrophobicity | Substrates | Biological activity | Proteins | Microscopy | Protein folding | Protein disulfide-isomerase | Dimers | Catalysis | Redox properties | Endoplasmic reticulum | Folding
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 3358 - 8
The stearoyl-CoA desaturase (SCD) family of enzymes catalyzes monounsaturated fatty acid synthesis by inserting a cis double bond at the Delta 9 position of... 
OCULAR SURFACE | PROTECTS MICE | DEFINITION | OXIDATION | DIAGNOSIS | INTERNATIONAL WORKSHOP | FILM | ATROPHY | DRY EYE | MULTIDISCIPLINARY SCIENCES | SECRETION | Enzymes | Phenotypes | Secretion | Glands | Lipids | Stearoyl-CoA desaturase | Conjunctiva | Desaturase | Metabolism | Fatty acids | Eye | Atrophy | Mucin | Rodents | Skin | Lipid metabolism
Journal Article
Journal of Vascular and Interventional Radiology, ISSN 1051-0443, 03/2019, Volume 30, Issue 3, pp. 446 - 452
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, pp. e99205 - e99205
Tear secretion is important as it supplies water to the ocular surface and keeps eyes moist. Both the parasympathetic and sympathetic pathways contribute to... 
SIGNAL-TRANSDUCTION | TYPE-3 | ROLES | CA2 | MULTIDISCIPLINARY SCIENCES | PROTEIN SECRETION | SJOGRENS-SYNDROME | LACRIMAL GLAND | Acinar Cells - metabolism | Acetylcholine - pharmacology | Tears - metabolism | Inflammation | Inositol 1,4,5-Trisphosphate Receptors - deficiency | Lacrimal Apparatus - metabolism | Mice, Knockout | Dry Eye Syndromes - pathology | Autoantibodies - immunology | Animals | Calcium Signaling - drug effects | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Dry Eye Syndromes - metabolism | Dry Eye Syndromes - veterinary | Immunoglobulins - blood | Ribonucleoproteins - immunology | Epithelium, Corneal - metabolism | Mice | Acinar Cells - drug effects | Lacrimal Apparatus - pathology | Epinephrine - pharmacology | Inositol 1,4,5-Trisphosphate Receptors - genetics | Epinephrine | Autoimmunity | Exhibitions | Inositol | Analysis | Neurosciences | Cornea | Sjogren's syndrome | Glands | Neurobiology | Science | Eye | Proteins | Tearing | Signal transduction | Receptors | Elevation | Histopathology | Pathways | Rodents | Eye (anatomy) | Inositol 1,4,5-trisphosphate receptors | Acinar cells | Immunoglobulins | Calcium (intracellular) | Autoantibodies | Secretion | Medicine | Brain research | Infiltration | Acetylcholine | Intracellular | Laboratory animals | Parasympathetic nervous system | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, pp. e99328 - e99328
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 04/2016, Volume 310, Issue 8, pp. H1003 - H1014
Caloric restriction (CR) confers cardioprotection against ischemia-reperfusion (I/R) injury. We previously found the essential roles of endothelial nitric... 
Ischemia-reperfusion | Complement | Sirt1 | Antioxidant | Sirtuin | Cardiomyocyte | antioxidant | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | NITRIC-OXIDE SYNTHASE | PROTEIN-KINASE | INJURY | ischemia-reperfusion | CELL-SURVIVAL | SIRTUINS | DIASTOLIC DYSFUNCTION | HEART | sirtuin | cardiomyocyte | PERIPHERAL VASCULAR DISEASE | MICE | complement | ISCHEMIA/REPERFUSION | Sirtuin 1 - metabolism | Phosphorylation | Complement Activation | Oxidative Stress | Ventricular Function, Left | Caloric Restriction | Stilbenes - pharmacology | Sirtuin 1 - genetics | Myocardial Reperfusion Injury - enzymology | Myocytes, Cardiac - enzymology | Myocardial Reperfusion Injury - pathology | Complement C3 - deficiency | Time Factors | Nitric Oxide Synthase Type III - metabolism | Sirtuin 1 - deficiency | Complement C3 - genetics | Myocardial Reperfusion Injury - genetics | Disease Models, Animal | Myocardial Reperfusion Injury - immunology | Complement C3 - metabolism | Isolated Heart Preparation | Mice, Inbred C57BL | Cells, Cultured | Genotype | Antioxidants - pharmacology | Rats, Sprague-Dawley | Myocardial Reperfusion Injury - physiopathology | Complement C3 - immunology | Mice, Knockout | Myocytes, Cardiac - pathology | Phenotype | Animals | Myocytes, Cardiac - drug effects | Myocardial Reperfusion Injury - prevention & control | Physiological aspects | Myocardial ischemia | Health aspects | Nitric oxide | Heart cells | Ischemia | Resveratrol | Heart | Cardiomyocytes | Rodents | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, pp. e33148 - e33148
Background: Decrease in lacrimal gland secretory function is related to age-induced dry eye disease. Lactoferrin, the main glycoprotein component of tears, has... 
OXIDATIVE DAMAGE | EPITHELIAL-CELLS | GASTROINTESTINAL-TRACT | DISEASE | BIOLOGY | RATS | TEAR FILM | IRON | PROTEIN PROFILES | DRY EYE SYNDROME | BOVINE LACTOFERRIN | Immunohistochemistry | Deoxyguanosine - blood | Gene Expression - drug effects | Anti-Infective Agents - pharmacology | Tumor Necrosis Factor-alpha - genetics | Male | Lactoferrin - administration & dosage | Lactoferrin - pharmacology | Aging | Lacrimal Apparatus Diseases - physiopathology | Deoxyguanosine - analogs & derivatives | Tears - drug effects | Microscopy, Electron, Transmission | Lacrimal Apparatus - drug effects | Administration, Oral | Lacrimal Apparatus - ultrastructure | Mice, Inbred C57BL | Chemokine CCL2 - genetics | Random Allocation | Lacrimal Apparatus - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Lacrimal Apparatus Diseases - prevention & control | Animals | Anti-Infective Agents - administration & dosage | Tears - secretion | Deoxyguanosine - metabolism | Mice | Dietary Supplements | Lacrimal Apparatus Diseases - pathology | Viral antibodies | Lysine | Lactoferrins | Antibodies | Eye diseases | Research | Gene expression | Euthanasia | Oxidative stress | Glands | Preserves | Lipid peroxidation | Lipids | Cardiovascular disease | Metastases | Eye | Proteins | Tearing | Lactoferrin | Rodents | Age | Deoxyribonucleic acid--DNA | Enzymes | Immunoglobulins | Internal medicine | Secretion | Glycoprotein | Oral administration | Inflammation | Tumor necrosis factor-α | Medicine | Lacrimal gland | Deoxyguanosine | Diet | Infiltration | Laboratory animals | Monocyte chemoattractant protein 1 | Tears | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article